Abstract: The present invention provides binding molecules that specifically bind to ILT3, e.g., human ILT3 (hILT3), on antigen presenting cells, such as for example, monocytes, macrophages and dendritic cells (DC), e.g., monocyte-derived dendritic cells (MDDC). Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof. Methods of using the binding molecules of the invention to detect human ILT3 or to modulate human ILT3 activity, either in vitro or in vivo, are also encompassed by the invention.

Abstract: One or more embodiments may include a method for remotely obtaining information about an energy source of a vehicle. Information identifying one or more vehicles and one or more drivers of the vehicles may be received at one or more computing devices remote from a vehicle. Instructions from the one or more remote computing devices may be transmitted requesting information from the identified vehicle(s) about a status of an energy source for the identified vehicle(s). The status information may be received at the remote computing device(s). Based on the energy source status information and the driver identifying information, a vehicle energy source status with respect to one or more attributes of the vehicle drivers may be calculated. Additionally, the vehicle energy source status may be displayed at the one or more devices.

Abstract: An iterative methodology and system (which can also be represented in software), with the option for continual improvement, for the interactive capture, merger, comparison, analysis, cloning and manipulation of anything in the unique universe medium or multiple universes mediums, be it real, virtual or imagined, including thought (of organic or non-organic or other nature), in real time or non-real time, where anything also includes anything infinitely small (or a small base volume of space known as a Senserom), to infinitely large (or a large encapsulating Senseroom volume known as a Senseverse) and can include multiple universes and Senserooms themselves impacting each other, static or dynamic changing over time periods, including the past, present and future. The full set of these infinite Senseroms and Senserooms is considered the Senseverse, which contains anything and/or everything real, virtual and imagined.

Abstract: One or more embodiments may include a method for remotely obtaining information about an energy source of a vehicle. Information identifying one or more vehicles and one or more drivers of the vehicles may be received at one or more computing devices remote from a vehicle. Instructions from the one or more remote computing devices may be transmitted requesting information from the identified vehicle(s) about a status of an energy source for the identified vehicle(s). The status information may be received at the remote computing device(s). Based on the energy source status information and the driver identifying information, a vehicle energy source status with respect to one or more attributes of the vehicle drivers may be calculated. Additionally, the vehicle energy source status may be displayed at the one or more devices.

Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.

Abstract: The present invention provides a candidate compound that is suitable for use in methods of treating animals (preferably mammals) and in the preparation of a medicament, wherein the candidate compound down regulates Cathepsin K activity.

Abstract: One or more embodiments may include a method for remotely obtaining information about an energy source of a vehicle. Information identifying one or more vehicles and one or more drivers of the vehicles may be received at one or more computing devices remote from a vehicle. Instructions from the one or more remote computing devices may be transmitted requesting information from the identified vehicle(s) about a status of an energy source for the identified vehicle(s). The status information may be received at the remote computing device(s). Based on the energy source status information and the driver identifying information, a vehicle energy source status with respect to one or more attributes of the vehicle drivers may be calculated. Additionally, the vehicle energy source status may be displayed at the one or more devices.

Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.

Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.

Abstract: The present invention relates generally to methods and devices for projecting articles. In particular, the present invention relates to a method and apparatus for projecting balls and like articles for interaction with a player where a player may, for example, be considered a human training for or playing a ball sport or, an animal such as a dog exercising by retrieving the projected article.

Abstract: A method for modifying plants by manipulating the activity of a combination of plant enzymes having starch synthase activity, in particular starch synthase II (SSII) and starch synthase III (SSIII). Modified plants, their use as food products and starch, in particular obtained from a modified potato plant, having novel properties and uses thereof are also disclosed.

Abstract: The present invention provides a candidate compound that is suitable for use in methods of treating animals (preferably mammals) and in the preparation of a medicament, wherein the candidate compound down regulates Cathepsin K activity.

Abstract: The invention is a modified withdrawal string for a tampon. The modified withdrawal string is nonabsorbant or monofilament string. The string has one or more anchor filaments at one or more locations along its length. Other attachments are a closed circumference at the end of the withdrawal string as well as a zigzag near the attachment end section of the string. The string can be textured nonabsorbant string.

Abstract: The present invention provides a candidate compound that is suitable for use in methods of treating animals (preferably mammals) and in the preparation of a medicament, wherein the candidate compound down regulates Cathepsin K activity.

Abstract: A mattress or surface protector is provided. The mattress or surface protector comprises a generally non-absorbent top layer and a waterproof/breathable bottom layer. The top layer and bottom layer are connected by borders providing a mechanism to inhibit spills from traversing the edges of the protector. The borders have straps that can be secured about the corners of the mattress or surface to anchor the protector.

Abstract: A concentrated cherry nutraceutical is prepared by extracting cherry juice from cherries and repeatedly freezing the cherry juice and separating cherry juice of increased concentration while maintaining the juice at freezing conditions.

Abstract: An expandable notebook for retaining and displaying papers or other materials includes a binder having a pair of decorative front and back covers connected to each other by an expandable spine. The spine is made of a plicated material for expansion and contraction, and has opposing slots on each side for receiving flexible, self-locking retainer straps which are adjustable for retaining various thicknesses of material. In a preferred embodiment each retainer strap is mounted through a pair of opposing slots formed on each side of the plicated spine, thereby surrounding the spine, and when locked in place the strap forms an adjustable loop which lies between the inner surfaces of the covers, to accommodate varied thicknesses of bound material within the loop and protected within the binder covers.

Abstract: This invention relates to a semidry or dry cherry product that retains the flavor and nutraceutical ingredients of the original cherries and also has extended shelf life.

Abstract: Compositions and methods for preventing hematophagous infestation of cattle are provided, directed at isolated proteins with antithrombin activity and nucleotide sequences encoding the proteins. The protein named thrombostasin is isolated from the salivary glands of Haematobia irritans. The compositions are useful as veterinary vaccines in prevention of blood-feeding in cattle by the infesting horn fly. The proteins of the invention are also useful in treatment of thrombosis.

Abstract: Resin modified elastomers, methods of making them and their uses. The method for making the elastomers comprises reacting in a diluent an ?SiH functional siloxane; a diene, diyne or ene-yne compound, a resin having the formula (R13SiO1/2)x(SiO4/2)y(R1SiO3/2)z where each R1 is independently a monovalent hydrocarbon group having 1 to 30 carbon atoms or an unsaturated hydrocarbon group having 2 to 30 carbon atoms x is ?1, y?0, z?0 and y+z?1.