Patents by Inventor Masaaki Mizuno

Masaaki Mizuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11977099
    Abstract: A method for manufacturing a semiconductor device in which probes and the layout of the electrode pads of a test element group (TEG) are associated is provided. As a semiconductor device is miniaturized, a scribe area on a wafer also tends to decrease. Accordingly, it is necessary to reduce the size of a TEG arranged in the scribe area, and efficiently arrange an electrode pad for probe contact. Thus, it is necessary to associate the probes and the layout of the electrode pad. According to the method, a layout of a TEG electrode pad corresponding to a plurality of probes arranged in a fan shape or probes manufactured by Micro Electro Mechanical Systems (MEMS) technology is provided.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: May 7, 2024
    Assignee: Hitachi High-Tech Corporation
    Inventors: Tomohisa Ohtaki, Takayuki Mizuno, Ryo Hirano, Toru Fujimura, Shigehiko Kato, Yasuhiko Nara, Katsuo Ohki, Akira Kageyama, Masaaki Komori
  • Publication number: 20220370510
    Abstract: The purpose of the present invention is to provide a novel medical application of pluripotent stem cells (muse cells) in regeneration medicine. The present invention provides a cell preparation and a pharmaceutical composition which are for amelioration and treatment of brain disorders resulting from fetal growth retardation, such as abnormal motor quality or abnormal neurological development, and which contain SSEA-3 positive pluripotent stem cells isolated from a mesenchymal tissue from a live body or cultured mesenchymal cells. It is assumed that this cell preparation is based on a mechanism where muse cells that are administered to objects having the disorders are engrafted on an impaired brain tissue, thereby ameliorating or treating the disorders.
    Type: Application
    Filed: July 29, 2022
    Publication date: November 24, 2022
    Applicants: National University Corporation Nagoya University, TOHOKU UNIVERSITY, NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, Life Science Institute, Inc.
    Inventors: Yoshiaki SATO, Yuma KITASE, Shinobu SHIMIZU, Masaaki MIZUNO, Masahiro HAYAKAWA, Mari DEZAWA, Masahiro TSUJI
  • Publication number: 20200197446
    Abstract: The purpose of the present invention is to provide a novel medical application of pluripotent stem cells (muse cells) in regeneration medicine. The present invention provides a cell preparation and a pharmaceutical composition which are for amelioration and treatment of brain disorders resulting from fetal growth retardation, such as abnormal motor quality or abnormal neurological development, and which contain SSEA-3 positive pluripotent stem cells isolated from a mesenchymal tissue from a live body or cultured mesenchymal cells. It is assumed that this cell preparation is based on a mechanism where muse cells that are administered to objects having the disorders are engrafted on an impaired brain tissue, thereby ameliorating or treating the disorders.
    Type: Application
    Filed: June 20, 2018
    Publication date: June 25, 2020
    Applicants: National University Corporation Nagoya University, TOHOKU UNIVERSITY, NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, Life Science Institute, Inc.
    Inventors: Yoshiaki SATO, Yuma KITASE, Shinobu SHIMIZU, Masaaki MIZUNO, Masahiro HAYAKAWA, Mari DEZAWA, Masahiro TSUJI
  • Publication number: 20190290702
    Abstract: The present invention addresses the problem of providing a novel use of pluripotent stem cells (Muse cells) for medical purposes in regenerative medicine. The present invention provides a cell preparation and a pharmaceutical composition both for ameliorating and treating perinatal brain damage including learning disability and motor disability, each of the cell preparation and the pharmaceutical composition containing SSEA-3-positive pluripotent stem cells isolated from a mesenchymal tissue collected from a living body or cultured mesenchymal cells. The cell preparation according to the present invention relies on a mechanism that Muse cells are administered to a subject having the above-mentioned damage to cause the engraftment of the Muse cells in a damaged brain tissue, thereby ameliorating and treating the damage.
    Type: Application
    Filed: May 16, 2017
    Publication date: September 26, 2019
    Applicants: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, LIFE SCIENCE INSTITUTE, INC.
    Inventors: Yoshiaki Sato, Toshihiko Suzuki, Shinobu Shimizu, Masaaki Mizuno, Masahiro Hayakawa, Mari Dezawa
  • Patent number: 10379008
    Abstract: A railway vehicle condition monitoring apparatus includes a detection device for detecting vehicle information represented by a wheel load or the like of a wheel included in a railway vehicle running on a railroad track, and a determination device including a classifier to which the vehicle information detected by the detection device is input and which outputs a vehicle condition such as the presence or absence of an abnormality of the railway vehicle. The classifier is generated by means of machine learning that uses training data of a railway vehicle of which the vehicle condition is known, the training data being the vehicle information and the vehicle condition which is known, the machine learning being performed so that when the vehicle information of the training data is input to the classifier, the classifier outputs the vehicle condition of the training data.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: August 13, 2019
    Assignees: NIPPON STEEL CORPORATION, THE UNIVERSITY OF TOKYO
    Inventors: Masaaki Mizuno, Masuhisa Tanimoto, Kensuke Nagasawa, Yoshihiro Suda, Shihpin Lin, Kensuke Kimoto
  • Publication number: 20190240262
    Abstract: The purpose of the present invention is to provide a novel medical use of pluripotent stem cells (Muse cells) in the regenerative medicine area. Provided are a cell preparation and a medicinal composition for ameliorating and treating chronic lung disease in newborns, said cell preparation and medicinal composition comprising SSEA-3-positive pluripotent stem cells isolated from a mesenchymal tissue in a living body or cultured mesenchymal cells. The cell preparation according to the present invention is based on a mechanism whereby the aforesaid disease is ameliorated and treated by administering Muse cells to a subject suffering from the disease and engrafting the cells in lung tissues.
    Type: Application
    Filed: August 3, 2017
    Publication date: August 8, 2019
    Applicants: National University Corporation Nagoya University, Life Science Institute, Inc., TOHOKU UNIVERSITY
    Inventors: Yoshiaki SATO, Toshihiko SUZUKI, Shinobu SHIMIZU, Masaaki MIZUNO, Masahiro HAYAKAWA, Mari DEZAWA
  • Publication number: 20180218780
    Abstract: A device, system, method, and computer program is provided that suppresses the disappearance of personal information in a handover process of personal information. A control unit of an information management device performs a process of receiving approval or disapproval of each user for each information system to use personal information of the user; in response to receiving disapproval of a first user for a first information system, a process of causing personal information of the first user stored in a first information server provided in the first information system to be sent from the first information server to a storage server; and in response to receiving approval of the first user for a second information system, a process of causing the personal information of the first user stored in the storage server to be sent from the storage server to a second information server provided in a second information system.
    Type: Application
    Filed: July 28, 2016
    Publication date: August 2, 2018
    Inventors: MASAAKI MIZUNO, AKITAKA SUGISHITA
  • Patent number: 9963157
    Abstract: A method of precisely measuring the track twist of a track on which a vehicle for commercial operation is travelling using this vehicle is to be provided. The method includes measuring a condition of a track (R) on which a vehicle for commercial operation (100) is travelling using this vehicle (100). The vehicle for commercial operation includes a bogie (10). The bogie includes four wheels (1) and primary springs (2) provided to correspond to the four wheels (1) and support the corresponding wheels (1), and is capable of measuring a wheel load of each of the four wheels (1). The method includes the steps of: measuring the wheel load of each wheel (1) (S13); calculating the displacement of each primary spring (2) based on the measured wheel load (S15); and calculating the track twist (h) of the track (R) based on the calculated displacements of the primary springs (2) (S18).
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: May 8, 2018
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Yohei Michitsuji, Ryo Matsui, Yasuhiro Sato, Hirotaka Mori, Makoto Shimizu, Jun Kurihara, Tomohiro Seki, Hiroshi Obayashi, Masaaki Mizuno, Masuhisa Tanimoto
  • Publication number: 20170363517
    Abstract: A railway vehicle condition monitoring apparatus includes a detection device for detecting vehicle information represented by a wheel load or the like of a wheel included in a railway vehicle running on a railroad track, and a determination device including a classifier to which the vehicle information detected by the detection device is input and which outputs a vehicle condition such as the presence or absence of an abnormality of the railway vehicle. The classifier is generated by means of machine learning that uses training data of a railway vehicle of which the vehicle condition is known, the training data being the vehicle information and the vehicle condition which is known, the machine learning being performed so that when the vehicle information of the training data is input to the classifier, the classifier outputs the vehicle condition of the training data.
    Type: Application
    Filed: December 15, 2015
    Publication date: December 21, 2017
    Inventors: Masaaki MIZUNO, Masuhisa TANIMOTO, Kensuke NAGASAWA, Yoshihiro SUDA, Shihpin LIN, Kensuke KIMOTO
  • Patent number: 9511783
    Abstract: A vehicle abnormality detecting apparatus 1 includes wheel load sensors 11 that are attached to right and left rails R constituting a track to measure wheel loads of wheels 3 provided in a vehicle 2; and a calculation unit 12 that is connected to the wheel load sensors 11. An index represented by wheel loads of a pair or more of right and left wheels 3 provided in at least one of bogies 4 and defined according to a type of vehicle abnormality as an index for detecting the vehicle abnormality is previously stored in the calculation unit 12. The calculation unit 12 calculates a value of the stored index from the wheel loads measured by the wheel load sensors 11 and transmitted from the wheel load sensors 11, and detects the abnormality of a running vehicle based on the calculated value of the index.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: December 6, 2016
    Assignees: NIPPON STEEL & SUMITOMO METAL CORPORATION, THE UNIVERSITY OF TOKYO
    Inventors: Yoshiyuki Shimokawa, Masaaki Mizuno, Yoshihiro Suda, Masahiko Aki, Hiroyuki Sugiyama, Koichi Ohtani, Masuhisa Tanimoto, Yoshifumi Komura, Jun Kurihara, Atsushi Iwamoto, Takuya Saito, Hiroshi Obayashi
  • Patent number: 9475507
    Abstract: To prevent separation of a truck frame and a wheel axle and to continue supporting a vehicle, even if damage has occurred to a steering device of a steering truck in which front-back support of a steering axle is performed only by a steering mechanism. A railway vehicle steering truck provided with an axle box suspension of a steering axle, which is designed to perform support in the front-back direction of an axle box which rotatably supports the steering axle, by means of a steering device having a steering link which is rotatably connected to the axle box, and a connecting link rotatably connected to a bolster, each of these being rotatably connected to a steering lever which is rotatably connected to the a truck frame.
    Type: Grant
    Filed: July 17, 2012
    Date of Patent: October 25, 2016
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Yoshiyuki Shimokawa, Masaaki Mizuno, Toshiyo Yamano, Tomoki Teramae
  • Patent number: 9452762
    Abstract: In the event that a steering device is damaged, the damaged component is prevented from dropping onto a surface of a track or prevented from making contact with a surface of a track, even if a component to prevent dropping is not newly installed. A railway vehicle steering truck having a steering device with a steering link which is rotatably connected to an axle box which supports a steering axle, and a connecting link rotatably connected to a bolster, and these are each rotatably connected to a steering lever which is rotatably connected to a truck frame. A length A1 or A2 from one center of rotation of the steering link is shorter than a radius B of a wheel that has reached a wear limit.
    Type: Grant
    Filed: July 17, 2012
    Date of Patent: September 27, 2016
    Assignee: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Yoshiyuki Shimokawa, Masaaki Mizuno, Toshiyo Yamano, Tomoki Teramae
  • Publication number: 20160194013
    Abstract: A method of precisely measuring the track twist of a track on which a vehicle for commercial operation is travelling using this vehicle is to be provided. The method includes measuring a condition of a track (R) on which a vehicle for commercial operation (100) is travelling using this vehicle (100). The vehicle for commercial operation includes a bogie (10). The bogie includes four wheels (1) and primary springs (2) provided to correspond to the four wheels (1) and support the corresponding wheels (1), and is capable of measuring a wheel load of each of the four wheels (1). The method includes the steps of: measuring the wheel load of each wheel (1) (S13); calculating the displacement of each primary spring (2) based on the measured wheel load (S15); and calculating the track twist (h) of the track (R) based on the calculated displacements of the primary springs (2) (S18).
    Type: Application
    Filed: September 4, 2014
    Publication date: July 7, 2016
    Inventors: Yohei MICHITSUJI, Ryo MATSUI, Yasuhiro SATO, Hirotaka MORI, Makoto SHIMIZU, Jun KURIHARA, Tomohiro SEKI, Hiroshi OBAYASHI, Masaaki MIZUNO, Masuhisa TANIMOTO
  • Publication number: 20150030693
    Abstract: An object of the present invention is to provide an antitumor aqueous solution and an anticancer agent, both of which can kill cancer cells while having virtually no effects on normal cells, and to provide methods for producing the antitumor aqueous solution and the anticancer agent. The method of the invention for producing an antitumor aqueous solution for killing cancer cells includes an aqueous solution preparation step of preparing an aqueous solution through addition, to water, of a solute containing at least one of disodium hydrogen phosphate (Na2HPO4), sodium hydrogen carbonate (NaHCO3), L-glutamine, L-histidine, and L-tyrosine disodium dihydrate (L-tyrosine.2Na.2H2O); and a plasma irradiation step of irradiating the aqueous solution with atmospheric pressure plasma generated in a plasma generation region by means of a plasma generator.
    Type: Application
    Filed: February 26, 2013
    Publication date: January 29, 2015
    Applicants: c/o NATONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, NU ECO ENGINEEERING CO., LTD.
    Inventors: Masaru Hori, Masaaki Mizuno, Fumitaka Kikkawa, Hiroaki Kajiyama, Fumi Utsumi, Kae Nakamura, Kenji Ishikawa, Keigo Takeda, Hiromasa Tanaka, Hiroyuki Kano
  • Publication number: 20150019071
    Abstract: A vehicle abnormality detecting apparatus 1 includes wheel load sensors 11 that are attached to right and left rails R constituting a track to measure wheel loads of wheels 3 provided in a vehicle 2; and a calculation unit 12 that is connected to the wheel load sensors 11. An index represented by wheel loads of a pair or more of right and left wheels 3 provided in at least one of bogies 4 and defined according to a type of vehicle abnormality as an index for detecting the vehicle abnormality is previously stored in the calculation unit 12. The calculation unit 12 calculates a value of the stored index from the wheel loads measured by the wheel load sensors 11 and transmitted from the wheel load sensors 11, and detects the abnormality of a running vehicle based on the calculated value of the index.
    Type: Application
    Filed: December 6, 2012
    Publication date: January 15, 2015
    Inventors: Yoshiyuki Shimokawa, Masaaki Mizuno, Yoshihiro Suda, Masahiko Aki, Hiroyuki Sugiyama, Koichi Ohtani, Masuhisa Tanimoto, Yoshifumi Komura, Jun Kurihara, Atsushi Iwamoto, Takuya Saito, Hiroshi Obayashi
  • Publication number: 20140158015
    Abstract: To prevent separation of a truck frame and a wheel axle and to continue supporting a vehicle, even if damage has occurred to a steering device of a steering truck in which front-back support of a steering axle is performed only by a steering mechanism. A railway vehicle steering truck 11 provided with an axle box suspension of a steering axle 2, which is designed to perform support in the front-back direction of an axle box 4 which rotatably supports the steering axle 2, by means of a steering device 3 having a steering link 2a which is rotatably connected to the axle box 4, and a connecting link 3c rotatably connected to a bolster 7, each of these being rotatably connected to a steering lever 3b which is rotatably connected to the a truck frame 6.
    Type: Application
    Filed: July 17, 2012
    Publication date: June 12, 2014
    Applicant: Nippon Steel & Sumitomo Metal Corporation
    Inventors: Yoshiyuki Shimokawa, Masaaki Mizuno, Toshiyo Yamano, Tomoki Teramae
  • Publication number: 20140137764
    Abstract: In the event that a steering device is damaged, the damaged component is prevented from dropping onto a surface of a track or prevented from making contact with a surface of a track, even if a component to prevent dropping is not newly installed. A railway vehicle steering truck having a steering device 1 with a steering link 1b which is rotatably connected to an axle box 4 which supports a steering axle 2, and a connecting link 1c rotatably connected to a bolster 5, and these are each rotatably connected to a steering lever 1a which is rotatably connected to a truck frame 3. A length A1 or A2 from one center of rotation of the steering link 1b is shorter than a radius B of a wheel that has reached a wear limit.
    Type: Application
    Filed: July 17, 2012
    Publication date: May 22, 2014
    Applicant: NIPPON STEEL & SUMITOMO METAL CORPORATION
    Inventors: Yoshiyuki Shimokawa, Masaaki Mizuno, Toshiyo Yamano, Tomoki Teramae
  • Patent number: 8075972
    Abstract: To provide an optical recording medium exhibiting favorable write/read characteristics in high-speed recording. In an optical recording medium including a reflective layer, a dye-containing recording layer, and a transparent resin layer on a substrate in this order, a barrier layer is disposed between the recording layer and the resin layer, where the barrier layer comprises a material having a bulk thermal conductivity M of 70 W/m·K or more at 300 K and has a thickness t less than 5 nm.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: December 13, 2011
    Assignee: Mitsubishi Kagaku Media Co., Ltd.
    Inventors: Shigeyuki Furomoto, Masaaki Mizuno, Naoyuki Uchida
  • Patent number: 7858167
    Abstract: A rewritable optical recording medium including: a substrate having a guide groove formed thereon, a phase-change type recording layer, a portion in a crystalline state of the phase-change type recording layer corresponds to an unrecorded or erased state, and a portion in an amorphous state of the phase-change type recording layer corresponds to a recorded state, so that an amorphous mark corresponding to the recorded state is formed upon irradiation with a recording laser beam. The phase-change type recording layer contains Sb as a main component, and further contains Ge and/or Te, a content of Ge is from 1 atomic % to 30 atomic %, and a content of Te is from 10 atomic % to 30 atomic %, and in the phase-change type recording layer, Sb/Te is at least 4.5, and the atomic ratio of Ge to Te is from 1:3 to 1:20.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: December 28, 2010
    Assignee: Mitsubishi Kagaku Media Co., Ltd.
    Inventors: Takashi Ohno, Masae Kubo, Michikazu Horie, Masaaki Mizuno, Hiroyuki Hoshino, Akio Okamuro
  • Patent number: 7609603
    Abstract: A rewritable optical recording medium includes a substrate and a phase-change type recording layer. A portion in a crystalline state corresponds to an unrecorded or erased state, and a portion in an amorphous state correspond to a recorded state, to record EFM modulated information by forming amorphous marks by irradiating the recording layer with a recording laser beam, and the recording is carried out by irradiating a recording laser beam having a wavelength of about 780 nm through an optical system having a numerical aperture NA of 0.5 or 0.55, at 24-times velocity or 32-times velocity of the reference velocity.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: October 27, 2009
    Assignee: Mitsubishi Kagaku Media Co., Ltd.
    Inventors: Takashi Ohno, Masae Kubo, Michikazu Horie, Masaaki Mizuno, Hiroyuki Hoshino, Akio Okamuro