Abstract: In an optical recording method used when information is recorded in a phase-change recording layer of a large-capacity rewritable optical recording medium such as a DVD-RW, one block pulse is used as a recording pulse for forming one recording mark when a recording velocity is higher than a recording linear velocity at which the rewritable optical recording medium can be rewritten, whereas a pulse train comprised of a plurality of short pulses is used as the recording pulse for forming one recording pulse when the recording velocity is within recording linear velocities at which the rewritable optical recording medium can be rewritten, whereby high-velocity recording is realized.

Abstract: To provide an optical recording medium exhibiting favorable write/read characteristics in high-speed recording. In an optical recording medium including a reflective layer, a dye-containing recording layer, and a transparent resin layer on a substrate in this order, a barrier layer is disposed between the recording layer and the resin layer, where the barrier layer comprises a material having a bulk thermal conductivity M of 70 W/m·K or more at 300 K and has a thickness t less than 5 nm.

Abstract: In an optical recording method used when information is recorded in a phase-change recording layer of a large-capacity rewritable optical recording medium such as a DVD-RW, one block pulse is used as a recording pulse for forming one recording mark when a recording velocity is higher than a recording linear velocity at which the rewritable optical recording medium can be rewritten, whereas a pulse train comprised of a plurality of short pulses is used as the recording pulse for forming one recording pulse when the recording velocity is within recording linear velocities at which the rewritable optical recording medium can be rewritten, whereby high-velocity recording is realized.

Abstract: The present invention provides CD-RW which makes high velocity recording at a level of at least 24-times velocity possible, rewritable DVD which makes high velocity recording at a level of at least 6-times velocity possible, and a recording method therefor, while maintaining interchangeability with conventional CD-RW standards and rewritable DVD standards. A rewritable optical recording medium comprising a substrate and a phase-change type recording layer, wherein a portion in a crystalline state corresponds to an unrecorded or erased state, and a portion in an amorphous state correspond to a recorded state, to record EFM modulated information by forming amorphous marks by irradiating the recording layer with a recording laser beam, and wherein recording is carried out by irradiating a recording laser beam having a wavelength of about 780 nm through an optical system having a numerical aperture NA of 0.5 or 0.

Abstract: A rewritable optical recording medium including: a substrate having a guide groove formed thereon, a phase-change type recording layer, a portion in a crystalline state of the phase-change type recording layer corresponds to an unrecorded or erased state, and a portion in an amorphous state of the phase-change type recording layer corresponds to a recorded state, so that an amorphous mark corresponding to the recorded state is formed upon irradiation with a recording laser beam. The phase-change type recording layer contains Sb as a main component, and further contains Ge and/or Te, a content of Ge is from 1 atomic % to 30 atomic %, and a content of Te is from 10 atomic % to 30 atomic %, and in the phase-change type recording layer, Sb/Te is at least 4.5, and the atomic ratio of Ge to Te is from 1:3 to 1:20.

Abstract: A rewritable optical recording medium includes a substrate and a phase-change type recording layer. A portion in a crystalline state corresponds to an unrecorded or erased state, and a portion in an amorphous state correspond to a recorded state, to record EFM modulated information by forming amorphous marks by irradiating the recording layer with a recording laser beam, and the recording is carried out by irradiating a recording laser beam having a wavelength of about 780 nm through an optical system having a numerical aperture NA of 0.5 or 0.55, at 24-times velocity or 32-times velocity of the reference velocity.

Abstract: In an optical recording method used when information is recorded in a phase-change recording layer of a large-capacity rewritable optical recording medium such as a DVD-RW, one block pulse is used as a recording pulse for forming one recording mark when a recording velocity is higher than a recording linear velocity at which the rewritable optical recording medium can be rewritten, whereas a pulse train comprised of a plurality of short pulses is used as the recording pulse for forming one recording pulse when the recording velocity is within recording linear velocities at which the rewritable optical recording medium can be rewritten, whereby high-velocity recording is realized.

Abstract: To obtain an optical information recording medium which is highly sensitive and excellent in durability against repeated recording and which is excellent in storage stability. An optical information recording medium is employed which comprises a substrate, a recording layer, a sulfur-containing protective layer, an interface layer in contact with the protective layer and a reflective layer in contact with the interface layer and containing Ag as the main component, wherein the interface layer contains Nb and/or Mo as the main component. By providing such an interface layer, the reaction between the reflective layer and the protective layer is effectively suppressed.

Abstract: In an optical recording method used when information is recorded in a phase-change recording layer of a large-capacity rewritable optical recording medium such as a DVD-RW, one block pulse is used as a recording pulse for forming one recording mark when a recording velocity is higher than a recording linear velocity at which the rewritable optical recording medium can be rewritten, whereas a pulse train comprised of a plurality of short pulses is used as the recording pulse for forming one recording pulse when the recording velocity is within recording linear velocities at which the rewritable optical recording medium can be rewritten, whereby high-velocity recording is realized.

Abstract: To obtain an optical information recording medium which is highly sensitive and excellent in durability against repeated recording and which is excellent in storage stability. An optical information recording medium is employed which comprises a substrate, a recording layer, a sulfur-containing protective layer, an interface layer in contact with the protective layer and a reflective layer in contact with the interface layer and containing Ag as the main component, wherein the interface layer contains Nb and/or Mo as the main component. By providing such an interface layer, the reaction between the reflective layer and the protective layer is effectively suppressed.

Abstract: The present invention provides CD-RW which makes high velocity recording at a level of at least 24-times velocity possible, rewritable DVD which makes high velocity recording at a level of at least 6-times velocity possible, and a recording method therefor, while maintaining interchangeability with conventional CD-RW standards and rewritable DVD standards.

Abstract: The use of recombinant adeno-associated virus (AAV) virions for the treatment of solid tumors is disclosed. The invention provides for the use of recombinant AAV virions to deliver an AAV vector containing a drug-susceptibility gene and a second gene capable of providing an ancillary effect to solid tumor cells. The second gene can be used to enhance the immunogenicity of the transduced tumor cell. Alternatively, the second gene can be used to provide a tumorstatic effect. The invention also provides for the use of recombinant AAV virions to deliver an interferon gene, or a tumor suppressor gene to provide a therapeutic effect in a transduced tumor cell.

Abstract: The use of recombinant adeno-associated virus (AAV) virions for the treatment of solid tumors is disclosed. The invention provides for the use of recombinant AAV virions to deliver an AAV vector containing a drug-susceptibility gene and a second gene capable of providing an ancillary effect to solid tumor cells. The second gene can be used to enhance the immunogenicity of the transduced tumor cell. Alternatively, the second gene can be used to provide a tumorstatic effect. The invention also provides for the use of recombinant AAV virions to deliver an interferon gene, or a tumor suppressor gene to provide a therapeutic effect in a transduced tumor cell.

Abstract: An optical phase-change disc comprises a substrate having thereon a spiral groove or concentric grooves for guiding a focused light beam, and a layer structure including a recording layer and protective layers sandwiching therebetween the recording layer. The groove has wobble for recording ATIP (absolute time information) or ADIP (address information). The following relationship between the groove width GW, beam diameter R.sub.0 and wobble amplitude a.sub.w :0.25.ltoreq.GW/R.sub.0 .ltoreq.0.45 or 0.65.ltoreq.GW/R.sub.0 ; and0.03.ltoreq.a.sub.w /GW.ltoreq.0.08hold for preventing distortion of the groove caused by repeated overwriting operation to improve reliability of the optical disc.

Abstract: An optical information recording medium comprising a substrate provided with periodically wobbling guide grooves with a track pitch of 1.6.+-.0.1 .mu.m, and a lower protective layer, a phase-change type recording layer, an upper protective layer and a reflective layer formed in this sequence on the substrate, for recording, retrieving and erasing amorphous marks in the guide grooves by modulation of light intensity of at least two levels by means of a focused light having a wavelength of 780.+-.30 nm applied from the side of the substrate opposite to the recording layer side so that a crystalline state with a reflectance of from 15 to 25% is an unrecorded state, and an amorphous state with a reflectance of less than 10% is a recorded state, wherein the grooves have a depth of from 25 to 45 nm and a width of from 0.4 to 0.6 .mu.m.

Abstract: An optical phase-change disc comprises a substrate having thereon a spiral groove or concentric grooves for guiding a focused light beam, and a layer structure including a recording layer and protective layers sandwiching therebetween the recording layer. The groove has wobble for recording ATIP (absolute time information) or ADIP (address information). The following relationship between the groove width GW, beam diameter R.sub.0 and wobble amplitude a.sub.w :0.25.ltoreq.GW/R.sub.0 .ltoreq.0.45 or 0.65.ltoreq.GW/R.sub.0 ; and0.03.ltoreq.a.sub.w /GW.ltoreq.0.08hold for preventing distortion of the groove caused by repeated overwriting operation to improve reliability of the optical disc.

Abstract: An optical information recording medium comprising a substrate provided with periodically wobbling guide grooves with a track pitch of 1.6.+-.0.1 .mu.m, and a lower protective layer, a phase-change type recording layer, an upper protective layer and a reflective layer formed in this sequence on the substrate, for recording, retrieving and erasing amorphous marks in the guide grooves by modulation of light intensity of at least two levels by means of a focused light having a wavelength of 780.+-.30 nm applied from the side of the substrate opposite to the recording layer side so that a crystalline state with a reflectance of from 15 to 25% is an unrecorded state, and an amorphous state with a reflectance of less than 10% is a recorded state, wherein the recording layer is a thin film of an alloy of My.sub.y (Sb.sub.x Te.sub.1-x).sub.1-y where 0.ltoreq.y<0.3, 0.5<x<0.

Abstract: An optical information recording medium for recording, retrieving and erasing mark length-modulated amorphous marks, which comprises a substrate, and a lower protective layer, a phase-change recording layer, an upper protective layer and a reflective layer having a thickness of from 40 to 300 nm and a volume resistivity of from 20 to 150 n.OMEGA..multidot.m, formed in this sequence on the substrate.

Abstract: The use of recombinant adeno-associated virus (AAV) virions for the treatment of solid tumors is disclosed. The invention provides for the use of recombinant AAV virions to deliver an AAV vector containing a drug-susceptibility gene and a second gene capable of providing an ancillary effect to solid tumor cells. The second gene can be used to enhance the immunogenicity of the transduced tumor cell. Alternatively, the second gene can be used to provide a tumorstatic effect. The invention also provides for the use of recombinant AAV virions to deliver an interferon gene, or a tumor suppressor gene to provide a therapeutic effect in a transduced tumor cell.

Abstract: An optical phase-change disc comprises a substrate having thereon a spiral groove or concentric grooves for guiding a focused light beam, and a layer structure including a recording layer and protective layers sandwiching therebetween the recording layer. The groove has wobble for recording ATIP (absolute time information) or ADIP (address information). The following relationship between the groove width GW, beam diameter R.sub.0 and wobble amplitude a.sub.w :0.25.ltoreq.GW/R.sub.0 .ltoreq.0.45or0.65.ltoreq.GW/R.sub.0 ;and0.03.ltoreq.a.sub.w /GW.ltoreq.0.08hold for preventing distortion of the groove caused by repeated overwriting operation to improve reliability of the optical disc.