Patents by Inventor Masahiko Iijima

Masahiko Iijima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210190806
    Abstract: An automatic analysis device has a plurality of types of photometers having different quantitative ranges, and an analysis control unit for quantifying the desired component in specimens based on measurement values of one or more photometers selected from among the plurality of types of photometers. The analysis control unit: sets a switching region in an overlap region of respective quantitative ranges of the plurality of types of photometers, said switching region having a greater width than does the variation in quantitative values of the desired component based on the measurement values of photometers having the same specimen; compares the quantitative value of a quantitative range portion that corresponds to the switching region and the quantitative values of the desired component based on the measurement values of the photometers; and selects a photometer to be used in quantitative output of the desired component from among the plurality of types of photometers.
    Type: Application
    Filed: March 10, 2021
    Publication date: June 24, 2021
    Inventors: Yuto KAZAMA, Masahiko IIJIMA, Sakuichiro ADACHI
  • Patent number: 10976333
    Abstract: An automatic analysis device has a plurality of types of photometers having different quantitative ranges, and an analysis control unit for quantifying the desired component in specimens based on measurement values of one or more photometers selected from among the plurality of types of photometers. The analysis control unit: sets a switching region in an overlap region of respective quantitative ranges of the plurality of types of photometers, said switching region having a greater width than does the variation in quantitative values of the desired component based on the measurement values of photometers having the same specimen; compares the quantitative value of a quantitative range portion that corresponds to the switching region and the quantitative values of the desired component based on the measurement values of the photometers; and selects a photometer to be used in quantitative output of the desired component from among the plurality of types of photometers.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: April 13, 2021
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Yuto Kazama, Masahiko Iijima, Sakuichiro Adachi
  • Publication number: 20200278366
    Abstract: Provided is an automatic analysis device that avoids carryover and prevents deterioration of analysis performance without controlling reaction cell position. This automatic analysis device is provided with: a reaction cell in which a sample and a reagent are mixed and allowed to react; a light source that radiates light onto the mixed liquid of the sample and the reagent, which has been dispensed into the reaction cell; a detector that detects the light radiated from the light source; and a cleaning mechanism that cleans the reaction cell. The cleaning mechanism includes an intake nozzle that draws in liquid from the reaction cell and a discharge nozzle that discharges the liquid into the reaction cell; the intake nozzle and the discharge nozzle can move vertically; and the intake nozzle is cleaned by lowering the intake nozzle into the reaction cell, in which a cleaning liquid or cleaning water have been accumulated, without drawing in the cleaning liquid or the cleaning water.
    Type: Application
    Filed: January 23, 2019
    Publication date: September 3, 2020
    Inventors: Rei KONISHI, Nobuhiko SASAKI, Masahiko IIJIMA
  • Publication number: 20200271677
    Abstract: The present invention makes it possible for an automated analyzer including two or more types of photometers to obtain suitable output of the measurement results of the plurality of photometers and suitable data alarm output even if there is an abnormality, or the like, at the time of measurement. This automated analyzer includes, for example, two types of photometers having different quantitative ranges and an analysis control unit for controlling analysis that includes measurement of a given sample using the two types of photometers. If two types of data alarms corresponding to abnormalities, or the like, during measurement have been added to the two types of measurement results from the two types of photometers, the analysis control unit selects measurement result and data alarm output corresponding to the combination of the two types of data alarms and outputs the same to a user as analysis results.
    Type: Application
    Filed: September 6, 2018
    Publication date: August 27, 2020
    Inventors: Yuto KAZAMA, Masahiko IIJIMA, Chie YABUTANI, Kenji KOGURE
  • Publication number: 20200241024
    Abstract: An automatic analysis device is provided with: a sample disk for holding a sample container that accommodates a sample; a reagent disk for holding a reagent container that accommodates a reagent; at least two different measuring units that respectively perform different types of analyses; a control part that controls the measuring units; and a display part that displays: a work flow area in which the flow of operation of the two or more measuring units is displayed; and an overview area in which the usable or unusable states of the respective measuring units are displayed, wherein the overview area has a unit necessity-of-use selection part that can select whether using each of the measuring units is necessary, and the control part controls the display part so as to change the display of the work flow area on the basis of the information set in the unit necessity-of-use selection part.
    Type: Application
    Filed: February 15, 2018
    Publication date: July 30, 2020
    Inventors: Chie YABUTANI, Takumi YAMADA, Masahiko IIJIMA
  • Patent number: 10603667
    Abstract: Provided are a device and a cleaning mechanism for a reaction container in the device that are characterized by being provided with: a reaction disk for holding a reaction container; a sample dispensing mechanism for dispensing a sample to the reaction container; a reagent dispensing mechanism for dispensing a reagent to the reaction container; an optical system comprising a light source for applying light to a mixture of the sample and the reagent dispensed to the reaction container, and a detector for detecting the light applied from the light source; and a cleaning mechanism for cleaning the reaction container, wherein the cleaning mechanism is provided with a cleaning liquid supply nozzle for supplying a cleaning liquid to the reaction container after an analysis, a cleaning liquid suction nozzle for suctioning the supplied cleaning liquid, and a cleaning tip provided on the lower end of the cleaning liquid suction nozzle, and the side surface of the cleaning tip is formed such that the width of the clean
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: March 31, 2020
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kei Shioya, Masahiko Iijima
  • Publication number: 20190369131
    Abstract: Addressing the problem of preventing contamination, the present invention is characterized by being provided with a reagent nozzle (H) for discharging a reagent (M1) at a predetermined discharge pressure to a reaction vessel (V) in which a specimen (M2) is accommodated, a control unit for controlling the horizontal position of the reagent nozzle (H) in accordance with the liquid amount of the reagent (M1) and the viscosity of the reagent (M1), a dispensing unit for dispensing the reagent (M1) into the reaction vessel (V), and a photometer for detecting light radiated to a mixture of the specimen (M2) and the reagent (M1), the control unit setting the horizontal position of the reagent nozzle (H) to the center position of the reaction vessel (V) when the liquid amount of the reagent (M1) is greater than the amount of the specimen (M2) and the viscosity of the reagent (M1) is equal to the viscosity of the specimen (M2) or lower than the viscosity of the specimen (M2).
    Type: Application
    Filed: February 27, 2018
    Publication date: December 5, 2019
    Inventors: Hiroki AKASE, Masahiko IIJIMA, Chie YABUTANI, Takanori SAWADA, Rei KONISHI
  • Publication number: 20190351424
    Abstract: Provided are a device and a cleaning mechanism for a reaction container in the device that are characterized by being provided with: a reaction disk for holding a reaction container; a sample dispensing mechanism for dispensing a sample to the reaction container; a reagent dispensing mechanism for dispensing a reagent to the reaction container; an optical system comprising a light source for applying light to a mixture of the sample and the reagent dispensed to the reaction container, and a detector for detecting the light applied from the light source; and a cleaning mechanism for cleaning the reaction container, wherein the cleaning mechanism is provided with a cleaning liquid supply nozzle for supplying a cleaning liquid to the reaction container after an analysis, a cleaning liquid suction nozzle for suctioning the supplied cleaning liquid, and a cleaning tip provided on the lower end of the cleaning liquid suction nozzle, and the side surface of the cleaning tip is formed such that the width of the clean
    Type: Application
    Filed: February 15, 2018
    Publication date: November 21, 2019
    Inventors: Kei SHIOYA, Masahiko IIJIMA
  • Publication number: 20190346470
    Abstract: A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk; a first reagent dispensing mechanism that dispenses a reagent to reaction cells on the reaction disk; a photometer that irradiates a reaction solution in the reaction cell with light; a reaction cell cleaning mechanism; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to detect transmitted or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
    Type: Application
    Filed: July 24, 2019
    Publication date: November 14, 2019
    Inventors: Akihisa MAKINO, Hajime YAMAZAKI, Keiko YOSHIKAWA, Manabu ANDO, Masahiko IIJIMA
  • Patent number: 10416179
    Abstract: A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk; a first reagent dispensing mechanism that dispenses a reagent to reaction cells on the reaction disk; a photometer that irradiates a reaction solution in the reaction cell with light; a reaction cell cleaning mechanism; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to detect transmitted or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: September 17, 2019
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Akihisa Makino, Hajime Yamazaki, Keiko Yoshikawa, Manabu Ando, Masahiko Iijima
  • Publication number: 20190162744
    Abstract: An automatic analysis device has a plurality of types of photometers having different quantitative ranges, and an analysis control unit for quantifying the desired component in specimens based on measurement values of one or more photometers selected from among the plurality of types of photometers. The analysis control unit: sets a switching region in an overlap region of respective quantitative ranges of the plurality of types of photometers, said switching region having a greater width than does the variation in quantitative values of the desired component based on the measurement values of photometers having the same specimen; compares the quantitative value of a quantitative range portion that corresponds to the switching region and the quantitative values of the desired component based on the measurement values of the photometers; and selects a photometer to be used in quantitative output of the desired component from among the plurality of types of photometers.
    Type: Application
    Filed: June 16, 2017
    Publication date: May 30, 2019
    Inventors: Yuto KAZAMA, Masahiko IIJIMA, Sakuichiro ADACHI
  • Publication number: 20190025192
    Abstract: As a standard solution for evaluating a scattered light measuring optical system mounted on an automated analyzer, a standard solution containing an insoluble carrier at a concentration, at which transmittance is in a range of 10% to 50%, is used, and a light quantity of a light source is adjusted such that a scattered light detector outputs a predetermined value.
    Type: Application
    Filed: November 28, 2016
    Publication date: January 24, 2019
    Inventors: Sakuichiro ADACHI, Masahiko IIJIMA, Yuto KAZAMA
  • Publication number: 20170269113
    Abstract: A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk; a first reagent dispensing mechanism that dispenses a reagent to reaction cells on the reaction disk; a photometer that irradiates a reaction solution in the reaction cell with light; a reaction cell cleaning mechanism; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to detect transmitted or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
    Type: Application
    Filed: June 7, 2017
    Publication date: September 21, 2017
    Inventors: Akihisa MAKINO, Hajime YAMAZAKI, Keiko YOSHIKAWA, Manabu ANDO, Masahiko IIJIMA
  • Patent number: 9696329
    Abstract: A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk; a first reagent dispensing mechanism that dispenses a reagent to reaction cells on the reaction disk; a photometer that irradiates a reaction solution in the reaction cell with light; a reaction cell cleaning mechanism; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to detect transmitted or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: July 4, 2017
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Akihisa Makino, Hajime Yamazaki, Keiko Yoshikawa, Manabu Ando, Masahiko Iijima
  • Patent number: 9638640
    Abstract: An automatic analyzer which can reduce the effort necessary for conducting a test of limit of detection/limit of quantification properties and managing the test results is provided. Operation condition-setting means for conducting an evaluation test for at least one of a limit of detection and a limit of quantification for each measurement item, determination condition-setting means for setting a determination condition of the evaluation test, and a calculation unit for obtaining a measurement result of a dilution series containing different dilution concentrations by controlling the sample-dispensing mechanism, the reagent-dispensing mechanism and the measurement unit based on the set operation condition, and calculating a test result of the evaluation test from the measurement result of the dilution series based on the set determination condition are disposed.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: May 2, 2017
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Masahiko Iijima, Akihisa Makino, Manabu Ando
  • Patent number: 9575082
    Abstract: The automatic analysis device includes an analysis unit that corrects, based on a measured value at the time of a first light amount measurement with water dispensed in the reaction cell before the sample is dispensed therein; a measured value at the time of a second light amount measurement after the sample and a preprocessing reagent are dispensed into the reaction cell; a liquid amount in the reaction cell at the time of the second light amount measurement; and a liquid amount in the reaction cell at the time of a third light amount measurement after the reaction reagent has been dispensed into the reaction cell and before the reaction reagent and the substance to be measured react with each other.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: February 21, 2017
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Sakuichiro Adachi, Hajime Yamazaki, Masahiko Iijima, Shigeki Matsubara
  • Patent number: 9557264
    Abstract: To enable determination of if there is an influence of foreign-body reactions on the result of quantitative determination conducted with a scattered light measurement method. Proposed is an automatic analysis device including a light source configured to irradiate a reaction solution with light, a plurality of light receivers configured to receive scattered light generated from the reaction solution at different light-receiving angles, a first data processing unit configured to process reaction process data measured by one of the light receivers to quantitatively determine a concentration of a substance in the reaction solution, and a second data processing unit configured to determine if the quantitative determination of the concentration of the substance has been performed normally on the basis of a ratio of a plurality of computed values, the plurality of computed values having been calculated from a plurality of pieces of reaction process data measured by the respective light receivers.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: January 31, 2017
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Sakuichiro Adachi, Hajime Yamazaki, Masahiko Iijima
  • Patent number: 9506942
    Abstract: An automatic analyzer detects measurement value abnormalities stemming from reaction process anomalies caused by the presence of foreign matter or bubbles. It is determined whether the results of concentration calculation based on light quantity data from multiple target detectors each fall within an applicable determination range. If the results fall within the determination range, an average value of the results of concentration calculation with the target detectors is calculated, and if not, an out-of-determination-range flag is given. A default fluctuation range is retrieved regarding the average value of the results of concentration calculation. The fluctuation range of the results of concentration calculation with the multiple target detectors is calculated.
    Type: Grant
    Filed: November 22, 2012
    Date of Patent: November 29, 2016
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Akihisa Makino, Masahiko Iijima, Akiko Watanabe
  • Patent number: D838381
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: January 15, 2019
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Ai Masuda, Hiroyuki Noda, Akihito Wakui, Masahiko Iijima
  • Patent number: D849264
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: May 21, 2019
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Ai Masuda, Hiroyuki Noda, Mitsuru Oonuma, Keiko Yoshikawa, Masahiko Iijima