Abstract: A biogenic substance concentration measuring apparatus includes an optical measuring apparatus for measuring optical properties of a first substrate and a second substrate by using a cell for biogenic substance concentration measurement that includes: the first substrate on which a plurality of first metallic nanorods, each of which is modified with a substance that bonds specifically to a test substance, are immobilized such that the long axes thereof are aligned in the same direction; and the second substrate on which a plurality of second metallic nanorods, each of which is modified with a blocking substance, are immobilized such that the long axes thereof are aligned perpendicularly to the long axes of the first metallic nanorods on the first substrate, and calculates a biogenic substance concentration with high accuracy from the optical properties.

Abstract: One of the purposes of the present invention is to provide a biogenic substance concentration measuring method with improved measuring accuracy. An embodiment of the present invention provides a method for measuring a concentration of a biogenic substance contained in a living body, the method comprises steps of preparing a measuring device, wherein the measuring device comprises a light source, an optical filter, and a light receiver; irradiating different focused lights from the light source onto a particle chip implanted in a skin though a position on the surface of the skin to generate corresponding reflected lights; calculating the concentration of the biogenic substance on the basis of the difference of signals obtained from the reflected lights.

Abstract: One of the purposes of the present invention is to provide a biogenic substance concentration measuring method with improved measuring accuracy. An embodiment of the present invention provides a method for measuring a concentration of a biogenic substance contained in a living body, the method comprises steps of preparing a measuring device, wherein the measuring device comprises a light source, an optical filter, and a light receiver; irradiating a substantially-parallel light from the light source onto a particle chip implanted in a skin though a position on the surface of the skin to generate a reflected light; inclining the light source and calculating the concentration of the biogenic substance on the basis of the difference of signals before and after the inclination.

Abstract: The object of the present invention is to provide a method for measuring concentration of a biological substance contained in a living body in which deterioration of the accuracy due to the reflected light and the interruption component is suppressed. Linear-polarized light is emitted to a particle chip implanted in the skin with modulating its modulating direction continuously. A surface enhanced Raman scattering light of the biological substance generated on the particle chip. A concentration of the biological substance is calculated based on the received signal. The receiving signal satisfy the following equation (III). [Math.

Abstract: The present invention provides an apparatus for biogenic substance concentration measurement including: a cell including therein a first region, a second region, and a test solution retention space; a light source; a polarizing plate; and a photoreceiver, in which a plurality of first metallic nanorods each having a first antibody on a surface thereof are immobilized on the first region, a plurality of second metallic nanorods each having a second antibody on a surface thereof are immobilized on the second region, the respective long axes of the plurality of first metallic nanorods are aligned in the same direction, the respective long axes of the plurality of second metallic nanorods are aligned in the same direction, the long-axis direction of the first metallic nanorod is orthogonal to the long-axis direction of the second metallic nanorod, and at least one of the polarizing plate and the cell is capable of rotation with an optical axis as the rotation axis.

Abstract: The present invention provides an apparatus for biogenic substance concentration measurement including: a cell including therein a first region, a second region, and a test solution retention space; a light source; a polarizing plate; and a photoreceiver, in which a plurality of first metallic nanorods each having a first antibody on a surface thereof are immobilized on the first region, a plurality of second metallic nanorods each having a second antibody on a surface thereof are immobilized on the second region, the respective long axes of the plurality of first metallic nanorods are aligned in the same direction, the respective long axes of the plurality of second metallic nanorods are aligned in the same direction, the long-axis direction of the first metallic nanorod is orthogonal to the long-axis direction of the second metallic nanorod, and at least one of the polarizing plate and the cell is capable of rotation with an optical axis as the rotation axis.

Abstract: A device for measuring the concentration of a biological constituent based on infrared radiation emitted by a subject's eardrum with the influence of the eardrum's thickness taken into account is provided. The biological constituent concentration measuring device includes: a detecting section for detecting infrared radiation emitted by an eardrum; an acquisition section for acquiring thickness information about the thickness of the eardrum; and a computing section for figuring out the concentration of the biological constituent based on the infrared radiation detected and the thickness information acquired. The infrared radiation emitted by the eardrum is subject to the influence of the subject's eardrum thickness. Therefore, by calculating the biological constituent concentration based on not only the infrared radiation detected but also the eardrum thickness information, the biological constituent concentration can be measured highly accurately.

Abstract: A device for measuring the concentration of a biological constituent based on infrared radiation emitted by a subject's eardrum with the influence of the eardrum's thickness taken into account is provided. The biological constituent concentration measuring device includes: a detecting section for detecting infrared radiation emitted by an eardrum; an acquisition section for acquiring thickness information about the thickness of the eardrum; and a computing section for figuring out the concentration of the biological constituent based on the infrared radiation detected and the thickness information acquired. The infrared radiation emitted by the eardrum is subject to the influence of the subject's eardrum thickness. Therefore, by calculating the biological constituent concentration based on not only the infrared radiation detected but also the eardrum thickness information, the biological constituent concentration can be measured highly accurately.

Abstract: A bioinformation measurement device that enables further accurate bioinformation measurement is provided.

Abstract: To enable the user to see if the field of view of an infrared sensor faces an eardrum direction. A biological information collecting device (100) includes: an infrared sensor (108) for sensing the infrared radiation emitted from inside an acoustic foramen (200); an acoustic wave output section (152) that is arranged so as to emit an acoustic wave toward the field of view (F) of the infrared sensor (108); and a computing section (110) for deriving biological information based on the output of the infrared sensor (108).

Abstract: A biological constituent concentration measuring device that can measure a biological constituent concentration highly accurately using a radiation that has come from an eardrum is provided. A measuring device for measuring concentration of a biological constituent includes: an image capturing section for capturing an image of an eardrum; a processing section for generating tilt information concerning tilt of the eardrum based on a first image capturing information obtained by capturing an image of a first area of the eardrum and a second image capturing information obtained by capturing an image of a second area of the eardrum, which is different from the first area; an infrared sensor for sensing infrared radiation that has been radiated from the eardrum; and a computing section for calculating the concentration of a biological constituent based on the infrared radiation sensed and the tilt information.

Abstract: The present invention provides an optical element for measuring information of living body for noninvasively measuring a body fluid component in a test sample of living body with high accuracy, stability, and ease. The optical element includes a light incident surface, a contact surface contacting living body and having a groove to protrude living body and a light emission surface, in which a light incident from the light incident surface is applied to living body, and the light absorbed and scattered by living body is received and emitted from the light emission surface, a light transmittance controlling means is formed from the bottom part of the valley part of the groove, on at least a part of a wall surface of the light incident surface side and/or on a wall surface of the light emission surface side of the groove.

Abstract: To achieve a reliable and easy measurement of a concentration of a target component in an organism, in an optical element including: a first light-entrance plane, a body tissue contact-plane provided with a groove portion to be brought into contact with a body tissue, and a first light-exit plane; the groove portion includes a second light-entrance plane and a second light-exit plane; light that entered through the first light-entrance plane is applied to the body tissue protruded by the groove portion via the second light-entrance plane, and light absorbed by the body tissue and/or scattered, and entered through the second light-entrance plane exits the first light-exit plane; and a normal line of the plane opposing the body tissue contact-plane, and a plane made by a normal line of the second light-entrance plane and a normal line of the second light-exit plane intersect with each other.

Abstract: In order to precisely determine a stable measuring region appropriate for a measurement of biological information, and to measure a concentration of a specific component, i.e. biological information, without inconsistency, a biological information measuring device is provided with, a measuring region determining means for determining a measuring region in between an eponychium and a distal interphalangeal joint; an information detector for applying a light to measuring region; a light source for entering a light to information detector; a light detector for detecting a light which exits from the information detector; and a processor for measuring specific component based on information obtained from light detector.

Abstract: In order to solve the problem of a prior art biological attribute measuring device, i.e., measurement data is apt to vary because of unstable contact due to difficulty in controlling a thickness of a saliva layer and pain caused during the measurement, is provided a biological attribute measuring device including a contact device having a portion, at least part of which is a curved surface, for abutting against a measuring region to apply light to the measuring region, a light detecting means for detecting at least one selected from the group consisting of transmitted light, reflected light, scattered light and transmitted/reflected light from the measuring region and a measuring means for measuring a specific component in the measuring region based on the detection result.

Abstract: An optical member for biological information measurement has a prism, which has a light incident surface being injected with emitted light, a living body tissue measuring section which a living body tissue contacts, and a light emitting surface which emits the light reflected by the living body tissue measuring section which the living body tissue contacts, or the light which has passed the living body tissue through the living body tissue measuring section which the living body tissue has contacted. A prism cover is provided so as to expose the living body tissue measuring section and to surround all or a part of the outer circumferential portion of the prism.

Abstract: The present invention provides easy and stable measurement of the concentration of a specific component contained in a living body, even when a fluid such as water, saliva or sweat is present between an optical element and the living body or when the measurement is taken at a plurality of measuring parts of a living body. In the measurement of the present invention, a calibration line to be used to correct the influence of a change of a fluid layer present between a living body and an optical element is determined, a measured value is corrected based on the calibration line and the concentration is obtained from the corrected value.

Abstract: To provide a concentration measuring method which enables a stable and highly accurate concentration measurement while avoiding the step of making a background measurement. The concentration measuring apparatus includes: a concentration measuring contact that is brought into contact with a subject of measurement; a light source that emits light and enters the light into the concentration measuring contact; a polarizer that takes out p-polarized and s-polarized light components from the light which is passed through the concentration measuring contact into the subject of measurement, transmitted in the subject of measurement, and returned to the concentration measuring contact; a photodetector that determines at least the quantities of the p-polarized and s-polarized light components taken out by the polarizer; and calculating means that calculates the concentration of a specific component contained in the subject of measurement based on the determined results.

Abstract: The present invention provides an optical element for measuring information of living body for noninvasively measuring a body fluid component in a test sample of living body with high accuracy, stability, and ease. The optical element includes a light incident surface, a contact surface contacting living body and having a groove to protrude living body and a light emission surface, in which a light incident from the light incident surface is applied to living body, and the light absorbed and scattered by living body is received and emitted from the light emission surface, a light transmittance controlling means is formed from the bottom part of the valley part of the groove, on at least a part of a wall surface of the light incident surface side and/or on a wall surface of the light emission surface side of the groove.

Abstract: An optical member for biological information measurement has a prism, which has a light incident surface being injected with emitted light, a living body tissue measuring section which a living body tissue contacts, and a light emitting surface which emits the light reflected by the living body tissue measuring section which the living body tissue contacts, or the light which has passed the living body tissue through the living body tissue measuring section which the living body tissue has contacted. A prism cover is provided so as to expose the living body tissue measuring section and to surround all or a part of the outer circumferential portion of the prism.