Abstract: A pyrimidone derivative having tau protein kinase 1 inhibitory activity which is represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof; useful for prventive and/or therapeutic treatment of diseass such as neurodegenerative diseases (e.g. Alzheimer disease); wherein Q represents CH or nitrogen atom; R represents a C1-C12 alkyl group; the ring of Formula (I): represents piperazine ring or piperidine ring; each X independently represents a C1-C8 alkyl group, an optionally partially hydrogenated C6-C10 aryl ring, an indan ring or the like; m represents an integer of 1 to 3; each independently represents a halogen atom, a hydroxy group, a cyano group, a C1-C6 alkyl group or the like; n represents an integer of 0 to 8; when X and Y or two Y groups are attached on the same carbon atom, they may combine to each other to form a C2-C6 alkylene group.

Abstract: The present invention relates to a compound of formula I, or a pharmaceutically acceptable salt thereof. Formula (I), wherein R1 and R2 are each independently H or alkyl; Y is an alkyl group. CONR3R4, COOR5SO2NR16R17, NHSO2R18 or CN; X is an aryl or heteroaryl group, each of which may be optionally substituted with one or more substituents selected from (CH2)mZ where Z is halogen, OH, CN, alkyl, alkoxy, NO2, CF3, CONR6R7, CN, NR8R9, COOR10 or NHCOR11 and m is 0 to 3; R3 to R11 are each independently H, alkyl or aryl, wherein said alkyl and aryl groups are optionally substituted by one or more substituents selected from halogen, OH, CN, alkyl, alkoxy, NO2, CF3, CONR12R13, CN, NH2, COOR14, NHCOR15, and CN; R12 to R18 are each independently H or alkyl, more preferably H or Me; n is 1 to 6; wherein the compound is other than 3?,5?-dimethyl-4-(1,1-dimethylheptyl)-1,1?-biphenyl-2-ol.

Abstract: A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof having inhibitory activity against tau protein kinase 1: wherein R1 represents a C1-C12 alkyl group which may be substituted; R represents, for example, a group represented by the following formula (II): wherein R2 and R3 independently represent a hydrogen atom or a C1-C8 alkyl group; R4 represents a benzene ring which may be substituted, a naphthalene ring which may be substituted, an indan ring which may be substituted, a tetrahydronaphthalene ring which may be substituted, or an optionally substituted heterocyclic ring having 1 to 4 hetero atoms selected from the group consisting of oxygen atom, sulfur atom and nitrogen atom, and having 5 to 10 ring-constituting atoms in total.

Abstract: A display allowing further miniaturization when including a plurality of display panels is obtained. This display comprises a first display panel formed on a substrate and a second display panel formed on the same substrate on a region different from that formed with the first display panel. Thus, the display can be further miniaturized as compared with that having a first display panel and a second display panel formed on different substrates.

Abstract: The invention relates to compounds of formula I, or pharmaceutically acceptable salts thereof, wherein X1, X2 and X3 are each independently where Y is an alkylene, alkenylene or alkynylene group, each of which may be optionally substituted with one or more substituents selected from alkyl, halo, CF3, OH, alkoxy, NH2, CN, NO2 and COOH; W is absent or is O, S or NH; R1, R2, R3 and R4 are each independently selected from H, alkyl, aryl and a protecting group P1; R7, R8 and R9 are each independently selected from H, alkyl, halo, CF3, OH, alkoxy, NH2, CN, NO2 and COOH; q and r are each independently 1, 2, 3 or 4; q? and r? are each independently 0, 1, 2 or 3, where q+q? and r+r? each equal 4; p is 1, 2, 3, 4 or 5, and p? is 0, 1, 2, 3 or 4, where p+p? is 5; n is 0, 1, 2, 3 . . .

Abstract: The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein Z is OR1 or NR1R2 wherein each of R1 and R2 is independently H, or a hydrocarbyl group; X is an alkylene, alkenylene, or alkynylene group, each of which may be optionally substituted by one or more substituents selected from alkyl, COOH, CO2-alkyl, alkenyl, CN, NH2, hydroxy, halo, alkoxy, CF3 and nitro; Y is a polar functional group selected from OH, NO2, CN, COR3, COOR3, NR3R4, CONR3R4, SO3H, SO2—R3, SO2NR3R4 and CF3, where each of R3 and R4 is independently H or a hydrocarbyl group; A is an aryl or heteroaryl group, each of which may be optionally substituted; and B is (CH2)n where n is 0, 1, 2, 3, 4 or 5; with the proviso that: (i) when A is phenyl, n is 0, and Z is OH, X—Y is other than meta-C?—C—(CH2)2CO2H, meta-C?—C—(CH2)2OH, meta-C?C—(CH2)2CO2Me, meta-(CH2)4CO2H, ortho-CH2CO2H, ortho-(CH2)2CO2H and ortho-(CH2)4CO2H; and (ii) when A is phenyl, n is 0, and Z is OMe, X—Y is other than meta-C?

Abstract: Image processing method and image processing apparatus capable of reducing data volume further after JPEG compression are provided. RGB data is first converted into YUV data, and then scale conversion of luminance value and color-difference value of the YUV data is performed. Discrete cosine transform of the scale-converted YUV data is performed, and the data after the discrete cosine transform is coded into a Huffman code.

Abstract: A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof useful as a tau protein kinase 1 inhibitor:wherein X represents CH or nitrogen atom; R1 represents a C?1#191-C?12#191 alkyl group which may be substituted; R2 represents a C?1#191-C?8#191 alkyl group which may be substituted, a benzene ring which may be substituted, a naphthalene ring which may be substituted, an indan ring which may be substituted, a tetrahydronaphthalene ring which may be substituted, or an optionally substituted heterocyclic ring having 1 to 4 hetero atoms selected from the group consisting of oxygen atom, sulfur atom, and nitrogen atom, and having 5 to 10 ring-constituting atoms in total.

Abstract: Novel compounds represented by the following formula (I) that act as a ligand to sigma receptor/binding cite and a medicament comprising the same as an active ingredient: wherein X represents an alkyl group, an aryl group, a heterocyclic group or the like; Q represents a group represented by —CH2—, —CO—, —O—, —CH(OR7)— or the like wherein R7 represents a hydrogen atom, an alkyl group or the like; n represents an integer of from 0 to 5; R1 and R2 each represent a hydrogen atom, an alkyl group or the like; B represents either of the following groups: wherein R3, R4, R5, and R6 each represent a hydrogen atom, a halogen atom, an alkoxyl group or the like; m represents 1 or 2; and the ring of: represents an aromatic heterocyclic ring.

Abstract: A pyrimidone derivative having tau protein kinase 1 inhibitory activity which is represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof; useful for prventive and/or therapeutic treatment of diseass such as neurodegenerative diseases (e.g. Alzheimer disease); wherein Q represents CH or nitrogen atom; R represents a C1-C12 alkyl group; the ring of Formula (I): represents piperazine ring or piperidine ring; each X independently represents a C1-C8 alkyl group, an optionally partially hydrogenated C6-C10 aryl ring, an indan ring or the like; m represents an integer of 1 to 3; each independently represents a halogen atom, a hydroxy group, a cyano group, a C1-C6 alkyl group or the like; n represents an integer of 0 to 8; when X and Y or two Y groups are attached on the same carbon atom, they may combine to each other to form a C2-C6 alkylene group.

Abstract: An active matrix type electroluminescence display device is provided which comprises a plurality of display pixels GS11, GS12, GS13, arranged in a matrix of rows and columns; gate signal lines GL1, GL2, Gli connected to and shared by a plurality of display pixels arranged in each row; and gate drive circuits for sequentially supplying a select signal SCAN to the gate signal lines GL1, GL2, GL3, Gli. Each display pixel includes an electroluminescence element, a first thin film transistor in which a display signal DATA is applied to the drain and which is switched on and off in response to the select signal SCAN, and a second thin film transistor for driving the EL element based on the display signal DATA. The gate drive circuits are placed so that each of the gate signal lines GL1, GL2, GL3, Gli is driven from both ends.

Abstract: An image forming apparatus includes: toner supply amount detecting means for detecting a toner supply amount to a developer tank; detecting means for detecting a signal value of each pixel of an image; and toner consumption amount estimating means for estimating a toner consumption amount, based on the signal value. The signal value detected by the detecting means is corrected in accordance with the toner supply amount detected by the toner supply amount detecting means. The toner consumption amount is estimated based on the signal value corrected. This allows the toner consumption amount to be always calculated accurately, regardless of a variation amongst various models, or a variation in a toner consumption characteristic due to aging, using environment, or the like.

Abstract: Test data terminals R-DATA, G-DATA, and B-DATA are provided with respect to video signal lines VL-R, VL-G, and VL-B, via switches SW-R, SW-G, and SW-B, respectively. The switches SW-R, SW-G, and SW-B are turned ON by receiving an H level input signal supplied from a test terminal SW. Thus, a test of a panel is performed before an external IC is connected to the panel. When the external IC is connected to the panel, on the other hand, these terminals used for the test are fixed to an L level, thereby preventing abnormal operations.

Abstract: An active matrix type electroluminescence display device comprises a plurality of display pixels GS11, GS12, GS13, etc. arranged in a matrix of rows and columns, each display pixel including an EL element, a first thin film transistor in which a display signal is applied to the drain and which is switched on and off in response to a select signal, a capacitance with one end connected to the source of the first thin film transistor for maintaining a voltage corresponding to the display signal, and a second thin film transistor for driving the EL element based on the display signal. The other ends of the capacitance of row display pixels are connected to and shared by a plurality of first capacitance lines HLA1, HLA2, HLA3, HLAi. Both ends of the plurality of first capacitance lines HLA1, HLA2, HLA3 are connected to and shared by second capacitance lines HLB1 and HLB2. A constant voltage is supplied to the second capacitance line.

Abstract: A low power-consumption active matrix display device including gate lines, drain lines, and pixel electrodes, which are arranged at intersections between the gate lines and the drain lines. A drain line driver is connected to the drain lines to select a drain line and provide the selected drain line with an image signal. A gate line driver is connected to the gate lines to select a predetermined gate line and provide the selected gate line with a gate signal. Level shifters are connected to the drain line driver to operate in a time-dividing manner. Each level shifter supplies the drain line driver with a boosted voltage.

Abstract: An insulator substrate (110) is provided with a display pixel region (200) comprising an electroluminescence element (160) having a cathode (167), emissive layer (166), and anode (161), and with first and second TFTs for driving the element. Surrounding the display pixel region (200), a peripheral drive circuit region (251) having a third TFT for driving each pixel is further provided on the insulator substrate (110). The cathode (167) is disposed in a region other than the peripheral drive circuit region (251). With this arrangement, generation of a back channel by applying the EL element potential to the cathode is prevented in a complementary TFT employed in the peripheral drive circuit region for controlling the display region, thereby suppressing changes in threshold values due to such back channel generation. As a result, an EL display device with reduced generation of penetration current and minimized increased current consumption is achieved.

Abstract: A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof having inhibitory activity against tau protein kinase 1: wherein R1 represents a C1-C12 alkyl group which may be substituted; R represents, for example, a group represented by the following formula (II): wherein R2 and R3 independently represent a hydrogen atom or a C1-C8 alkyl group; R4 represents a benzene ring which may be substituted, a naphthalene ring which may be substituted, an indan ring which may be substituted, a tetrahydronaphthalene ring which may be substituted, or an optionally substituted heterocyclic ring having 1 to 4 hetero atoms selected from the group consisting of oxygen atom, sulfur atom and nitrogen atom, and having 5 to 10 ring-constituting atoms in total.

Abstract: a pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof having inhibitory activity against tau protein kinase 1: wherein R1 represents a C1-C12 alkyl group which may be substituted; R represents, for example, a group represented by the following formula (II): wherein R2 and R3 independently represent a hydrogen atom or a C1-C8 alkyl group; R4 represents a benzene ring which may be substituted, a naphthalene ring which may be substituted, an indan ring which may be substituted, a tetrahydronaphthalene ring which may be substituted, or an optionally substituted heterocyclic ring having 1 to 4 heteno atoms selected from the group consisting of oxygen atom, sulfur atom and nitrogen atom, and having 5 to 10 ring-constituting atoms in total.

Abstract: A wide line portion is drawn from a cathode while another wide line portion is formed by gathered lines extending from cathode terminals. A contact of realtively large size is formed in a region where the two wide line portions overlap each other with an insulating film being interposed therebetween, so as to connect both wide line portions. Further, in this contact, the cathode terminals and the cathode are connected through an intermediate layer composed of a conductive oxide material. Thus, a reduction in the voltage to be applied to the cathode as a result of increased line resistance between the terminals and the cathode can be prevented, thereby preventing deterioration of display quality.

Abstract: There is provide a display which can prevent lowering of display quality caused by fluctuation of thickness of an orientation film. The display includes a display region having a reflective region and a transmissive region and comprises a first region having a convex insulating film formed in a region corresponding to the reflective region on a substrate, and an orientation film formed so as to cover the convex insulating film. A second region in which the convex insulating film is not formed is continuously formed among adjacent pixels.