Abstract: A sheet conveying apparatus including: a skew feeding correcting portion configured to correct skew feeding of a sheet, the skew feeding correcting portion including: a rotary member pair configured to convey the sheet; a shutter member configured to abut against a leading edge of a sheet being conveyed, and having a home position; and a moving member arranged with a gap formed between the moving member and the shutter member positioned in the home position, such that the shutter member is moveable independently from the home position up to a point of engagement with the moving member, when the gap is closed, and such that the moving member is movable integrally with the shutter member while the gap is closed, wherein the rotary member pair is arranged to nip a sheet during a period in which the shutter member is configured to move integrally with the moving member.

Abstract: Provided is an image forming apparatus including an apparatus electric-contact that is connectable to a cartridge electric-contact of a cartridge, which is equipped with a memory that stores information related to the cartridge, such that the information is transmitted from the cartridge to a main apparatus body of the image forming apparatus; a connector having the apparatus electric-contact and a first engaging unit that is engageable with the cartridge so as to position the cartridge electric-contact and the apparatus electric-contact in a predetermined direction; and a connector holder that holds the connector in a movable manner. The connector holder has a second engaging unit that is engageable with the cartridge. The connector is movable in the predetermined direction.

Abstract: A cleaning device includes a cleaning unit configured to perform cleaning while in contact with a light transmission member, the cleaning unit being movable with respect to the transmission member in a first direction and a second direction differing in orientation. The cleaning unit includes a first cleaning portion and a second cleaning portion capable of coming into contact with the transmission member, moves in the first direction while keeping the first cleaning portion in contact with the transmission member and keeping the second cleaning portion away from the transmission member, and moves in the second direction while keeping the first cleaning portion away from the transmission member and keeping the second cleaning portion in contact with the transmission member.

Abstract: The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: wherein, R1 is a 5- to 6-membered ring group which may be substituted; X1 is a bond or the like; ring A is a 5- to 6-membered ring group which may be substituted; ring B is a 8- to 10-membered ring group which may be substituted; X2 is a bivalent group of 1 to 4 atoms; Z1 is a bivalent cyclic ring group or the like; Z2 is a bond or the like; and R2 is an amino group, a nitrogen-containing heterocyclic group which may be substituted or the like, or a salt thereof.

Abstract: The present invention provides an image forming apparatus including a moving member configured to support a first process cartridge and move the first process cartridge to a position for forming an image, and a detection unit configured to detect a state of a second process cartridge, in which the moving member holds the detection unit.

Abstract: This invention improves operability at a final stage of moving a slide unit in one direction. A withdrawal mechanism 14 includes a charge spring 45 charged with energy to interlock withdrawal of a sheet cassette, a lock member 39 locking the charge spring in a state of being charged with the energy, a ratchet mechanism releasing interlocking of the charge spring with the sheet cassette with respect to movement of the sheet cassette in a push-in direction, and an unlock member 70d interlocking the sheet cassette with the charge spring and releasing locking of the charge spring at a final stage of moving the sheet cassette in the push-in direction. The sheet cassette is moved in the push-in direction by the energy charged in the charge spring at the final stage of moving the sheet cassette in the push-in direction.

Abstract: The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: wherein, R1 is a 5- to 6-membered ring group which may be substituted; X1 is a bond or the like; ring A is a 5- to 6-membered ring group which may be substituted; ring B is a 8- to 10-membered ring group which may be substituted; X2 is a bivalent group of 1 to 4 atoms; Z1 is a bivalent cyclic ring group or the like; Z2 is a bond or the like; and R2 is an amino group, a nitrogen-containing heterocyclic group which may be substituted or the like, or a salt thereof.

Abstract: The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: wherein, R1 is a 5- to 6-membered ring group which may be substituted; X1 is a bond or the like; ring A is a 5- to 6-membered ring group which may be substituted; ring B is a 8- to 10-membered ring group which may be substituted; X2 is a bivalent group of 1 to 4 atoms; Z1 is a bivalent cyclic ring group or the like; Z2 is a bond or the like; and R2 is an amino group, a nitrogen-containing heterocyclic group which may be substituted or the like, or a salt thereof.

Abstract: The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: wherein, R1 is a 5- to 6-membered ring group which may be substituted; X1 is a bond or the like; ring A is a 5- to 6-membered ring group which may be substituted; ring B is a 8- to 10-membered ring group which may be substituted; X2 is a bivalent group of 1 to 4 atoms; Z1 is a bivalent cyclic ring group or the like; Z2 is a bond or the like; and R2 is an amino group, a nitrogen-containing heterocyclic group which may be substituted or the like, or a salt thereof.

Abstract: The present invention relates to a compound represented by the formula: wherein W is C(R1) or N, each A is an optionally substituted aryl group or a heteroaryl group, X1 is —NR3—Y1—, —O—, —S—, —SO—, —SO2— or —CHR3— wherein R3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R3 is optionally bonded to A to form an optionally substituted ring structure, R1 is a hydrogen atom or an optionally substituted group bonded via a carbon atom, a nitrogen atom or an oxygen atom, R2 is a hydrogen atom or optionally substituted group bonded via a carbon atom or a sulfur atom, or R1 and R2, or R2 and R3 are optionally bonded to form an optionally substituted ring structure, or a salt thereof, and a tyrosine kinase inhibitor or an agent for the prophylaxis or treatment of cancer, which contains this compound or a prodrug thereof.

Abstract: An image forming apparatus includes a rotating member, a driving force transmission unit configured to transmit drive force to the rotating member, a drive unit configured to rotationally drive the rotating member via the driving force transmission unit, a detecting unit configured to detect a velocity of the rotating member and generate velocity data based in the detected velocity, and a control unit configured to control the drive unit based on the velocity data. The control unit calculates a correction value to be added to a drive velocity instruction value so as to cancel velocity variation of velocity data during one rotation of the rotating member, and a correction value is controlled so as to eliminate a difference between a correction drive instruction value obtained by adding a correction value to a drive velocity instruction value and the drive velocity instruction value.

Abstract: An image forming apparatus for forming an image on a recording material is constituted by an image bearing member, a driving source, a first pulley rotatable by actuation of the driving source, a second pulley, connected to a rotatable member, for transmitting rotation of the driving source to the image bearing member, a belt supported by the first pulley and the second pulley, a first pressing member which is disposed upstream from the first pulley with respect to a rotational direction of the drum and located closer to the second pulley than a rotation axis of the first pulley so as to press the first pulley through the belt, and a second pressing member disposed at a position substantially symmetrically opposite from the first pressing member with respect to a line connecting the rotation axis of the first pulley and a rotation axis of the second pulley so as to press the first pulley through the belt.

Abstract: This invention improves operability at a final stage of moving a slide unit in one direction. A withdrawal mechanism 14 includes a charge spring 45 charged with energy to interlock withdrawal of a sheet cassette, a lock member 39 locking the charge spring in a state of being charged with the energy, a ratchet mechanism releasing interlocking of the charge spring with the sheet cassette with respect to movement of the sheet cassette in a push-in direction, and an unlock member 70d interlocking the sheet cassette with the charge spring and releasing locking of the charge spring at a final stage of moving the sheet cassette in the push-in direction. The sheet cassette is moved in the push-in direction by the energy charged in the charge spring at the final stage of moving the sheet cassette in the push-in direction.

Abstract: A compound of the formula: wherein ring A is a 7-membered or 8-membered nitrogen-containing ring optionally further substituted, ring B is an optionally substituted aryl group or an optionally substituted heteroaryl group, X1 is a group represented by —NR3—Y1—, —O—, —S—, —SO—, —SO2— or —CHR3— wherein R3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R3 may be bonded to the carbon atom of ring B to form an optionally substituted ring structure, and Y1 is a bond or an optionally substituted alkylene, R1 is a hydrogen atom, or an optionally substituted group bonded via a carbon atom or a sulfur atom, the formula shows a single bond or a double bond, when R2 is —R2, R2 is a hydrogen atom, or an optionally substituted group bonded via a carbon atom, a nitrogen atom, an oxygen atom or a sulfur atom, and when R2 is ?R2, R2 is an oxo group, an optionally substituted alkylidene group, or an optionally substituted imino group.

Abstract: The present invention provides a compound represented by the formula: wherein R1a is a hydrogen atom, R2a is a C1-6 alkyl group substituted by a group represented by —NR6a—CO—(CH2)n—SO2— optionally halogenated C1-4 alkyl wherein n is an integer of 1 to 4, R6a is a hydrogen atom or a C1-4 alkyl group, and —(CH2)n— is optionally substituted by C1-4 alkyl, R3a is a hydrogen atom or a C1-6 alkyl group, R4a is a halogen atom or a C1-6 alkyl group, R5a is a halogen atom or a C1-6 alkyl group, and Xa is a hydrogen atom or a halogen atom, or a salt thereof. The compound of the present invention has a superior tyrosine kinase inhibitory action, is highly safe, and is sufficiently satisfactory as a pharmaceutical product.

Abstract: An image reading apparatus includes a reader unit configured to read an image of a conveyed document at a reading position, a transparent member arranged at the reading position and including a conductive layer, which is earthed, on a surface of the transparent member, a conveyance unit configured to convey the document to the reading position, and a guide member that is earthed, provided along the surface of the transparent member, and positioned so as to intersect with a conveyance direction of the document conveyed by the conveyance unit.

Abstract: The present invention relates to a compound represented by the formula: wherein W is C(R1) or N, each A is an optionally substituted aryl group or a heteroaryl group, X1 is —NR3—Y1—, —O—, —S—, —SO—, —SO2— or —CHR3— wherein R3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R3 is optionally bonded to A to form an optionally substituted ring structure, R1 is a hydrogen atom or an optionally substituted group bonded via a carbon atom, a nitrogen atom or an oxygen atom, R2 is a hydrogen atom or optionally substituted group bonded via a carbon atom or a sulfur atom, or R1 and R2, or R2 and R3 are optionally bonded to form an optionally substituted ring structure, or a salt thereof, and a tyrosine kinase inhibitor or an agent for the prophylaxis or treatment of cancer, which contains this compound or a prodrug thereof.

Abstract: The present invention relates to a compound represented by the formula: wherein W is C(R1) or N, each A is an optionally substituted aryl group or a heteroaryl group, X1 is —NR3—Y1—, —O—, —S—, —SO—, —SO2— or —CHR3— wherein R3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R3 is optionally bonded to A to form an optionally substituted ring structure, R1 is a hydrogen atom or an optionally substituted group bonded via a carbon atom, a nitrogen atom or an oxygen atom, R2 is a hydrogen atom or optionally substituted group bonded via a carbon atom or a sulfur atom, or R1 and R2, or R2 and R3 are optionally bonded to form an optionally substituted ring structure, or a salt thereof, and a tyrosine kinase inhibitor or an agent for the prophylaxis or treatment of cancer, which contains this compound or a prodrug thereof.

Abstract: The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: wherein, R1 is a 5- to 6-membered ring group which may be substituted; X1 is a bond or the like; ring A is a 5- to 6-membered ring group which may be substituted; ring B is a 8- to 10-membered ring group which may be substituted; X2 is a bivalent group of 1 to 4 atoms; Z1 is a bivalent cyclic ring group or the like; Z2 is a bond or the like; and R2 is an amino group, a nitrogen-containing heterocyclic group which may be substituted or the like, or a salt thereof.

Abstract: The present invention relates to a compound represented by the formula: wherein W is C(R1) or N, each A is an optionally substituted aryl group or a heteroaryl group, X1 is —NR3—Y1—, —O—, —S—, —SO—, —SO2— or —CHR3— wherein R3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R3 is optionally bonded to A to form an optionally substituted ring structure, R1 is a hydrogen atom or an optionally substituted group bonded via a carbon atom, a nitrogen atom or an oxygen atom, R2 is a hydrogen atom or optionally substituted group bonded via a carbon atom or a sulfur atom, or R1 and R2, or R2 and R3 are optionally bonded to form an optionally substituted ring structure, or a salt thereof, and a tyrosine kinase inhibitor or an agent for the prophylaxis or treatment of cancer, which contains this compound or a prodrug thereof.