Patents by Inventor Masataka Nakamura
Masataka Nakamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11358352Abstract: The present invention provides a method for producing a medical device, which includes a step of disposing a solution containing a hydrophilic polymer having a hydroxyl group and an amide group and a substrate on or in a support, and heating the solution and the substrate through the support, wherein a pH of the solution before starting the heating step is in a range of 2.0 or higher and 6.0 or lower, and a pH of the solution after completion of the heating step is in a range of 2.0 or higher and 6.0 or lower. The present invention provides a method for simply producing a medical device. More particularly, the present invention provides a method for simply producing a medical device whose surface is hydrophilized.Type: GrantFiled: April 26, 2018Date of Patent: June 14, 2022Assignee: TORAY INDUSTRIES, INC.Inventors: Rumiko Kitagawa, Masataka Nakamura
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Publication number: 20220168471Abstract: A device includes a substrate and a hydrophilic polymer layer made of a hydrophilic polymer having a hydroxyl group. The hydrophilic polymer layer having a hydroxyl group is fixed to at least a part of a surface of the substrate and the hydrophilic polymer further has an amide group. A liquid film retention time of the device is 15 seconds or more. The device has a surface of a substrate which is hydrophilized. A method for producing the device by a simple method is also disclosed.Type: ApplicationFiled: April 30, 2021Publication date: June 2, 2022Applicant: Toray Industries, Inc.Inventors: Rumiko Kitagawa, Masataka Nakamura
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Publication number: 20220008631Abstract: A medical device including a substrate and a hydrophilic polymer layer and satisfying the following conditions: (1) that the hydrophilic polymer layer is on at least a part of the substrate; (2) that the hydrophilic polymer layer contains: a hydrophilic polymer having an acidic group; and a compound having an acidic group and a ring structure; and (3) that a time during which a liquid film is retained on the surface of the medical device (a liquid film retention time) is 10 seconds or more after the medical device is stationarily immersed in a phosphate buffer solution, pulled up from the phosphate buffer solution, and retained in the air. The present invention provides a medical device in which a surface of a substrate is hydrophilized, and a method for manufacturing same by a simple method.Type: ApplicationFiled: December 5, 2019Publication date: January 13, 2022Applicant: TORAY INDUSTRIES, INC.Inventors: Rumiko KITAGAWA, Masataka NAKAMURA
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Publication number: 20220008630Abstract: Disclosed is a medical device including a substrate and a polymer layer, wherein the polymer layer is provided on at least a part of a surface of the substrate and satisfies the following requirements: (a) a water content of the medical device in hydrated state is in a range of 28% by mass or more and 50% by mass or less; (b) the substrate has a 2-alkoxyethyl group; and (c) the polymer layer contains one type of a carboxylic acid group-containing polymer and one type of a copolymer having an amide structure. The present invention provides a medical device capable of maintaining surface wettability for a long time.Type: ApplicationFiled: September 13, 2019Publication date: January 13, 2022Applicant: TORAY INDUSTRIES, INC.Inventors: Hirokazu IIMORI, Rumiko KITAGAWA, Tomohiro KATO, Masataka NAKAMURA
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Publication number: 20210395526Abstract: A medical device including an internal wetting agent and a copolymer of a silicone monomer and satisfying the following conditions: (1) that the internal wetting agent contains a copolymer of an open-chain compound having an acidic group and an open-chain compound having an amide group; (2) that the internal wetting agent is contained in the range of from 0.1 to 10% by mass with respect to the whole medical device; and (3) that the copolymer of a silicone monomer has a hydroxyl group and that the content ratio of the hydroxyl group in the silicone monomer is in the range of from 0.0005 to 0.01 equivalents/g. A medical device containing an internal wetting agent and having excellent transparency and hydrophilicity can be obtained.Type: ApplicationFiled: December 5, 2019Publication date: December 23, 2021Applicant: TORAY Industries, Inc.Inventors: Rumiko KITAGAWA, Masataka NAKAMURA
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Patent number: 11202849Abstract: To provide a medical device including a substrate and a hydrophilic polymer layer formed on at least a part of the substrate, which satisfies the following conditions (a) to (d): (a) a polymer constituting the hydrophilic polymer layer is a hydrophilic polymer having an acidic group; (b) the hydrophilic polymer layer has a thickness of 1 nm or more and less than 100 nm; (c) a number ratio of basic group/acidic group of the hydrophilic polymer layer is 0.2 or less; and (d) a liquid film retention time at 40 minutes after ultrasonic cleaning in a phosphate buffer solution is 15 seconds or more. The present invention provides a medical device in which a surface of a substrate is hydrophilized, and a method for manufacturing same by a simple method.Type: GrantFiled: August 7, 2018Date of Patent: December 21, 2021Assignee: TORAY INDUSTRIES, INC.Inventors: Rumiko Kitagawa, Masataka Nakamura
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Patent number: 11119338Abstract: A soft contact lens has low water content or no water content. The soft contact lens includes: a circular central part positioned at a center of the soft contact lens; an intermediate part positioned at an outer peripheral side of the central part and forming an annular shape having a center coaxial with the central part; and an outer edge part positioned at an outer peripheral side of the intermediate part and forming an annular shape having a center coaxial with the central part. Respective radii of curvature of the central part, the intermediate part, and the outer edge part are different from each other, and a sagittal depth of the soft contact lens is within a range of a sagittal depth in a case where the entire soft contact lens is formed in a range of a radius of curvature ±0.2 mm of the outer edge part.Type: GrantFiled: April 3, 2017Date of Patent: September 14, 2021Assignees: SEED CO., LTD., TORAY INDUSTRIES, INC.Inventors: Akira Nakamura, Tsutomu Fukushima, Rumiko Kitagawa, Masataka Nakamura
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Patent number: 11108071Abstract: The present invention relates to a method for producing a polymer electrolyte molded article, which comprises forming a polymer electrolyte precursor having a protective group and an ionic group, and deprotecting at least a portion of protective groups contained in the resulting molded article to obtain a polymer electrolyte molded article. According to the present invention, it is possible to obtain a polymer electrolyte material and a polymer electrolyte molded article, which are excellent in proton conductivity and are also excellent in fuel barrier properties, mechanical strength, physical durability, resistance to hot water, resistance to hot methanol, processability and chemical stability. A polymer electrolyte fuel cell using a polymer electrolyte membrane, polymer electrolyte parts or a membrane electrode assembly can achieve high output, high energy density and long-term durability.Type: GrantFiled: January 11, 2019Date of Patent: August 31, 2021Assignee: TORAY INDUSTRIES, INC.Inventors: Daisuke Izuhara, Hiroshi Taiko, Yuriko Okada, Shinya Adachi, Masataka Nakamura
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Patent number: 11045574Abstract: Disclosed is a device including a substrate and a gel layer made of a hydrophilic polymer having a hydroxyl group. The gel layer is fixed to at least a part on a surface of the substrate in a thickness of 1 nm to 3,000 nm and an elastic modulus of a device surface is 6.00×103 Pa or less.Type: GrantFiled: February 22, 2017Date of Patent: June 29, 2021Assignee: Toray Industries, Inc.Inventors: Rumiko Kitagawa, Masataka Nakamura
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Patent number: 11020511Abstract: A device includes a substrate and a hydrophilic polymer layer made of a hydrophilic polymer having a hydroxyl group. The hydrophilic polymer layer having a hydroxyl group is fixed to at least a part of a surface of the substrate and the hydrophilic polymer further has an amide group. A liquid film retention time of the device is 15 seconds or more. The device has a surface of a substrate which is hydrophilized. A method for producing the device by a simple method is also disclosed.Type: GrantFiled: February 22, 2017Date of Patent: June 1, 2021Assignee: TORAY INDUSTRIES, INC.Inventors: Rumiko Kitagawa, Masataka Nakamura
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Publication number: 20210147602Abstract: The present invention provides a contact lens composition that is polymerizable in a mold and that can easily be peeled from a mold, a cured material of the contact lens composition, a contact lens in which the cured material of the contact lens composition is disposed in at least a center part thereof, and a method for manufacturing the contact lens. This contact lens composition contains (a) a polymerizable crosslinking agent having a multi-ring alicyclic hydrocarbon structure and (b) silicone having a radical polymerizable group.Type: ApplicationFiled: May 10, 2018Publication date: May 20, 2021Applicant: Toray Industries, Inc.Inventors: Hirokazu Iimori, Masataka Nakamura
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Publication number: 20210015960Abstract: Disclosed are: a polymer for treating the surface of a medical device such as a contact lens to suppress the reduction in lubricity of the device even when the device is scrubbed; a medical device having the polymer on the surface so that the reduction in lubricity over time is suppressed; and a wetting agent containing the polymer. The polymer for treating the surface is a copolymer which is water-soluble and includes as constitutional units the following monomers A and B: monomer A: a monomer containing a (meth)acryloyl group and an ester or amide structure in a molecule, in which the ester or amide structure is not constituted by including a part of the (meth)acryloyl group; monomer B: a monomer containing a (meth)acrylamide group in a molecule and having a structure different from that of the monomer A.Type: ApplicationFiled: September 29, 2020Publication date: January 21, 2021Applicant: Toray Industries, Inc.Inventors: Kyohei Yamashita, Takeshi Ishigaki, Masataka Nakamura
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Publication number: 20200310161Abstract: A soft contact lens has low water content or no water content. The soft contact lens includes: a circular central part positioned at a center of the soft contact lens; an intermediate part positioned at an outer peripheral side of the central part and forming an annular shape having a center coaxial with the central part; and an outer edge part positioned at an outer peripheral side of the intermediate part and forming an annular shape having a center coaxial with the central part. Respective radii of curvature of the central part, the intermediate part, and the outer edge part are different from each other, and a sagittal depth of the soft contact lens is within a range of a sagittal depth in a case where the entire soft contact lens is formed in a range of a radius of curvature ±0.2 mm of the outer edge part.Type: ApplicationFiled: April 3, 2017Publication date: October 1, 2020Applicants: Seed Co., Ltd., Toray Industries, Inc.Inventors: Akira Nakamura, Tsutomu Fukushima, Rumiko Kitagawa, Masataka Nakamura
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Publication number: 20200215226Abstract: To provide a medical device including a substrate and a hydrophilic polymer layer formed on at least a part of the substrate, which satisfies the following conditions (a) to (d): (a) a polymer constituting the hydrophilic polymer layer is a hydrophilic polymer having an acidic group; (b) the hydrophilic polymer layer has a thickness of 1 nm or more and less than 100 nm; (c) a number ratio of basic group/acidic group of the hydrophilic polymer layer is 0.2 or less; and (d) a liquid film retention time at 40 minutes after ultrasonic cleaning in a phosphate buffer solution is 15 seconds or more. The present invention provides a medical device in which a surface of a substrate is hydrophilized, and a method for manufacturing same by a simple method.Type: ApplicationFiled: August 7, 2018Publication date: July 9, 2020Applicant: Toray Industries, Inc.Inventors: Rumiko Kitagawa, Masataka Nakamura
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Publication number: 20200164112Abstract: A medical device including a silicone hydrogel which is less likely to harden due to drying, and which is less likely to cause stimulation at a site in contact with a human body, is disclosed. The medical device includes a silicone hydrogel satisfying the following conditions: (1) the water content in hydrous state is within the range of 10% by mass to 70% by mass; (2) the content of silicon atoms with respect to the total mass in dry state is within the range of 8% by mass to 30% by mass; and (3) the tensile elastic modulus in dry state is within the range of 0.1 MPa to 3.5 MPa.Type: ApplicationFiled: April 19, 2018Publication date: May 28, 2020Applicant: Toray Industries, Inc.Inventors: Tomohiro Kato, Masataka Nakamura
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Publication number: 20200139653Abstract: The present invention provides a method for producing a medical device, which includes a step of disposing a solution containing a hydrophilic polymer having a hydroxyl group and an amide group and a substrate on or in a support, and heating the solution and the substrate through the support, wherein a pH of the solution before starting the heating step is in a range of 2.0 or higher and 6.0 or lower, and a pH of the solution after completion of the heating step is in a range of 2.0 or higher and 6.0 or lower. The present invention provides a method for simply producing a medical device. More particularly, the present invention provides a method for simply producing a medical device whose surface is hydrophilized.Type: ApplicationFiled: April 26, 2018Publication date: May 7, 2020Applicant: Toray Industries, Inc.Inventors: Rumiko Kitagawa, Masataka Nakamura
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Patent number: 10591749Abstract: Disclosed is a medical device having an elastic modulus of 100 kPa or more and 2,000 kPa or less, a water content of 10% by mass or less, a tensile elongation of 50% or more and 3,000% or less, and a dynamic contact angle (advancing angle) relative to a borate buffer of 80° or less. The present invention can significantly reduce or avoid a phenomenon of adhesion to a surface when contacted with a surface outside or inside the body, which has hitherto been regarded as a problem in a conventional medical device.Type: GrantFiled: August 10, 2012Date of Patent: March 17, 2020Assignee: Toray Industries, Inc.Inventors: Masataka Nakamura, Rumiko Kitagawa, Ryuta Tamiya
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Patent number: 10398639Abstract: A skin adhesive sheet is disclosed which is good in tackiness to the skin surface, does not easily dry even when used for a long time, can maintain flexibility, and is small in the shape variation. The skin adhesive sheet includes a copolymer containing the following components A and C as polymerization components, and having a water content less than 10% by mass: component A: a polysiloxane macromonomer having a plurality of polymerizable functional groups per molecule, and having a number average molecular weight of 6,000 or more; and component C: a polymerizable monomer having an alkyl group and having no fluoroalkyl group.Type: GrantFiled: May 27, 2015Date of Patent: September 3, 2019Assignee: Toray Industries, Inc.Inventors: Rumiko Kitagawa, Masataka Nakamura
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Patent number: 10376174Abstract: In order to provide an electrode equipped with an insulating wall having excellent patterning properties as well as excellent biocompatibility, there is provided an electrode including, on a substrate, an electrode element; and an insulating wall formed around the electrode element, constituted of a polysiloxane compound (component A) having, per molecule, two or more functional groups selected from the group consisting of a (meth)acryloyl group, a styrenic vinyl group, a vinyl ester group, a maleic acid ester group and a maleimide group, and formed from a polymer obtained by reaction of the functional groups.Type: GrantFiled: February 5, 2015Date of Patent: August 13, 2019Assignees: TORAY INDUSTRIES, INC.Inventors: Takao Someya, Tsuyoshi Sekitani, Kazunori Kuribara, Ryuta Tamiya, Masataka Nakamura
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Publication number: 20190160205Abstract: The present invention is capable of providing a medical device that not only exhibits superior water-leakage properties and anti-contaminant properties, but also has highly durable lubricity. The present invention also may provide a method of manufacturing the medical device via a simple process without inducing substrate deformation. Specifically, provided is a medical device having a layer containing two or more types of ionic polymer on at least part of the surface of a medical device substrate, at least one of the two or more types of ionic polymer being a block polymer that has a hydrophobic segment.Type: ApplicationFiled: July 27, 2017Publication date: May 30, 2019Applicant: Toray Industries, Inc.Inventors: Tomohiro Kato, Masataka Nakamura