Abstract: The present invention relates to a method for producing a polymer electrolyte molded article, which comprises forming a polymer electrolyte precursor having a protective group and an ionic group, and deprotecting at least a portion of protective groups contained in the resulting molded article to obtain a polymer electrolyte molded article. According to the present invention, it is possible to obtain a polymer electrolyte material and a polymer electrolyte molded article, which are excellent in proton conductivity and are also excellent in fuel barrier properties, mechanical strength, physical durability, resistance to hot water, resistance to hot methanol, processability and chemical stability. A polymer electrolyte fuel cell using a polymer electrolyte membrane, polymer electrolyte parts or a membrane electrode assembly can achieve high output, high energy density and long-term durability.

Abstract: Disclosed are: a polymer for treating the surface of a medical device such as a contact lens to suppress the reduction in lubricity of the device even when the device is scrubbed; a medical device having the polymer on the surface so that the reduction in lubricity over time is suppressed; and a wetting agent containing the polymer. The polymer for treating the surface is a copolymer which is water-soluble and includes as constitutional units the following monomers A and B: monomer A: a monomer containing a (meth)acryloyl group and an ester or amide structure in a molecule, in which the ester or amide structure is not constituted by including a part of the (meth)acryloyl group; monomer B: a monomer containing a (meth)acrylamide group in a molecule and having a structure different from that of the monomer A.

Abstract: The present invention relates to a silicone acrylamide copolymer of high acrylamide monomer content which has transparency and low modulus, employing the following configuration. The copolymer is suitably used for various kinds of medical devices, particularly ophthalmic lenses such as a contact lens, an intraocular lens, an artificial cornea, and is especially suitable for a contact lens. A copolymer comprising (A) a multi-functional (meth)acrylamide monomer having at least one siloxane bond and at least two (meth)acrylamide groups within a molecule and (B) a mono-functional linear silicone (meth)acrylamide monomer.

Abstract: The present invention relates to a method for producing a polymer electrolyte molded article, which comprises forming a polymer electrolyte precursor having a protective group and an ionic group, and deprotecting at least a portion of protective groups contained in the resulting molded article to obtain a polymer electrolyte molded article. According to the present invention, it is possible to obtain a polymer electrolyte material and a polymer electrolyte molded article, which are excellent in proton conductivity and are also excellent in fuel barrier properties, mechanical strength, physical durability, resistance to hot water, resistance to hot methanol, processability and chemical stability. A polymer electrolyte fuel cell using a polymer electrolyte membrane, polymer electrolyte parts or a membrane electrode assembly can achieve high output, high energy density and long-term durability.

Abstract: To obtain a hydrophilic macromonomer mixture which is a highly polymerized hydrophilic macromonomer, has few components not bonded to the polymer chain after polymerization, and is less likely to leaching. Provided is a macromonomer mixture containing macromonomer A being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a polymerization initiator at an end thereof; and macromonomer B being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a chain transfer agent at an end thereof.

Abstract: A device includes a substrate and a hydrophilic polymer layer made of a hydrophilic polymer having a hydroxyl group. The hydrophilic polymer layer having a hydroxyl group is fixed to at least a part of a surface of the substrate and the hydrophilic polymer further has an amide group. A liquid film retention time of the device is 15 seconds or more. The device has a surface of a substrate which is hydrophilized. A method for producing the device by a simple method is also disclosed.

Abstract: Disclosed is a device including a substrate and a gel layer made of a hydrophilic polymer having a hydroxyl group. The gel layer is fixed to at least a part on a surface of the substrate in a thickness of 1 nm to 3,000 nm and an elastic modulus of a device surface is 6.00×103 Pa or less.

Abstract: To obtain a hydrophilic macromonomer mixture which is a highly polymerized hydrophilic macromonomer, has few components not bonded to the polymer chain after polymerization, and is less likely to leaching. Provided is a macromonomer mixture containing macromonomer A being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a polymerization initiator at an end thereof; and macromonomer B being a macromonomer having a group obtained by further introducing a polymerizable group into a reactive group derived from a chain transfer agent at an end thereof.

Abstract: In order to provide a silicone hydrogel which has high uniformity in polymerization rates of polymerization components used for copolymerization, excellent mechanical characteristics, excellent optical characteristics and good shape recoverability and in order to also provide various medical devices and ocular lenses having an excellent balance among elasticity, wettability and transparency, the present invention provides a silicone hydrogel which has a repeating unit derived from a monofunctional linear silicone (meth)acrylate and a repeating unit derived from a hydrophilic (meth)acrylate, and wherein the content of the repeating units derived from (meth)acrylates is more than 80% by mass.

Abstract: The hydroxyalkyl acrylate according to the present invention is characterized in that a content amount of an ester generated from acrylic acid dimer and an alkylene oxide is not more than 0.10 mass %. The method for producing a hydroxyalkyl acrylate according to the present invention is characterized in comprising the step of reacting acrylic acid with an alkylene oxide in the presence of a catalyst, wherein a content amount of acrylic acid dimer in the raw material acrylic acid is not more than 3.00 mass %.

Abstract: A skin adhesive sheet is disclosed which is good in tackiness to the skin surface, does not easily dry even when used for a long time, can maintain flexibility, and is small in the shape variation. The skin adhesive sheet includes a copolymer containing the following components A and C as polymerization components, and having a water content less than 10% by mass: component A: a polysiloxane macromonomer having a plurality of polymerizable functional groups per molecule, and having a number average molecular weight of 6,000 or more; and component C: a polymerizable monomer having an alkyl group and having no fluoroalkyl group.

Abstract: The present invention relates to a silicone acrylamide copolymer of high acrylamide monomer content which has transparency and low modulus, employing the following configuration. The copolymer is suitably used for various kinds of medical devices, particularly ophthalmic lenses such as a contact lens, an intraocular lens, an artificial cornea, and is especially suitable for a contact lens. A copolymer comprising (A) a multi-functional (meth)acrylamide monomer having at least one siloxane bond and at least two (meth)acrylamide groups within a molecule and (B) a mono-functional linear silicone (meth)acrylamide monomer.

Abstract: The invention relates to a stable bicarbonate ion-containing drug solution, particularly a bicarbonate-containing drug solution for dialysis in which the stability has been improved by the presence of a phosphate ion. Further, the invention relates to a drug solution for acute blood purification, particularly a dialysate and a substitution liquid for acute blood purification to be mixed before use containing the drug solution. Still further, the invention relates to a dialysate and a substitution liquid for acute blood purification to be mixed before use in which the formation of insoluble fine particles or precipitates is prevented for a long time after mixing and with which hypokalemeia and hypophosphatemia are not caused.

Abstract: A medical device includes a layer made of an acidic polymer and a basic polymer formed on at least a part of a surface of a water-containing base material, wherein at least one kind of an acidic polymer and a basic polymer forming the acidic polymer or the basic polymer is a polymer having a hydroxy group.

Abstract: Provided are a low hydrous soft ophthalmic lens that can remarkably reduce or avoid a phenomenon in which a lens sticks to a cornea when worn and can reduce a decrease in the performance of a coating layer when rubbing the low hydrous soft ophthalmic lens for cleaning and a method for manufacturing the same. The low hydrous soft ophthalmic lens has a layer formed of a hydrophilic polymer on at least part of the surface of a base material containing a polysiloxane compound, and at least part of the inside of the layer is cross-linked.

Abstract: The present invention relates to a silicone acrylamide copolymer of high acrylamide monomer content which has transparency and low modulus, employing the following configuration. The copolymer is suitably used for various kinds of medical devices, particularly ophthalmic lenses such as a contact lens, an intraocular lens, an artificial cornea, and is especially suitable for a contact lens. A copolymer comprising (A) a multi-functional (meth)acrylamide monomer having at least one siloxane bond and at least two (meth)acrylamide groups within a molecule and (B) a mono-functional linear silicone (meth)acrylamide monomer.

Abstract: In order to provide a silicone hydrogel which has high uniformity in polymerization rates of polymerization components used for copolymerization, excellent mechanical characteristics, excellent optical characteristics and good shape recoverability and in order to also provide various medical devices and ocular lenses having an excellent balance among elasticity, wettability and transparency, the present invention provides a silicone hydrogel which has a repeating unit derived from a monofunctional linear silicone (meth)acrylate and a repeating unit derived from a hydrophilic (meth)acrylate, and wherein the content of the repeating units derived from (meth)acrylates is more than 80% by mass.

Abstract: To provide a medical device which is excellent in wettability and lubricity and is also scarcely broken since it is soft, by a medical device in which a layer made of an acidic polymer and a basic polymer is formed on at least a part of a surface of a low water content soft base material, the low water content soft base material containing, as a main component, a copolymer containing a monofunctional monomer component M having one polymerizable functional group and one silicone moiety per molecule.

Abstract: The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas.

Abstract: In order to provide an electrode equipped with an insulating wall having excellent patterning properties as well as excellent biocompatibility, there is provided an electrode including, on a substrate, an electrode element; and an insulating wall formed around the electrode element, constituted of a polysiloxane compound (component A) having, per molecule, two or more functional groups selected from the group consisting of a (meth)acryloyl group, a styrenic vinyl group, a vinyl ester group, a maleic acid ester group and a maleimide group, and formed from a polymer obtained by reaction of the functional groups.