Abstract: The present disclosure relates to methods and assays for quantifying brain-derived exosomes in biological samples from subjects before, during, and after surgery. The disclosure also provides methods and compositions for measuring and/or prognosing brain damage during surgery. The compositions and methods of the disclosure are also useful for preventing and/or treating brain damage in subjects undergoing surgery and predicting postoperative cognitive dysfunction (POCD) and/or predicting postoperative delirium (POD).

Abstract: A gas detector comprises a gas detection unit and a filter introducing surrounding atmosphere to the gas detection unit. The filter comprises a gas-permeable organic polymer membrane having an acidic group or a basic group.

Abstract: A combined electric power generations' supply system includes an AC power generator that supplies power by off grid independent operation, a DC power supply device, an inverter that converts DC power output by the DC power supply device into AC power. The rotation calculation unit calculates a value relating to a rotation of a rotor when driving the virtual power generator according to an active power command based on a rotor model calculates a value relating to the rotation of the rotor of the virtual power generator and the active power command. The output determination unit determines values relating to an active power and a reactive power to be output to the inverter based on the calculated value relating to the rotation. The modulation control unit performs control of a pulse width modulation of the inverter based on the determined value relating to the active power and reactive power.

Abstract: A reignition processing device for a gas engine for executing a reignition process of a cylinder during operation of a gas engine having multiple cylinders is provided with: an execution permission unit configured to, when at least one of the cylinders misfires, perform permission determination whether to execute the reignition process of the misfiring cylinder, on the basis of a damage diagnosis result based on an in-cylinder pressure of the misfiring cylinder, presence or absence of abnormality in a control device which performs combustion control and combustion diagnosis of the gas engine, an operational history related to the misfiring cylinder, and an operational state of the gas engine; and a reignition execution unit configured to execute the reignition process of the misfiring cylinder that is permitted by the permission determination to execute the reignition process.

Abstract: A rotation calculation unit calculates a rotation speed of a virtual generator on the basis of a rotor model to simulate driving of the virtual generator and calculates the rotation speed of the virtual generator. A target power determination unit determines target values of active power and reactive power of an inverter on the basis of the calculated rotation speed. A command generation unit generates a control command for the inverter on the basis of the determined target values of the active power and the reactive power.

Abstract: The present invention relates to methods, compositions, and kits for detecting and quantitating exosomes and exosomal biomarkers and the use of exosomes and exosomal biomarkers in diagnostic and prognostic methods for various diseases and disorders.

Abstract: A reignition processing device for a gas engine for executing a reignition process of a cylinder during operation of a gas engine having multiple cylinders is provided with: an execution permission unit configured to, when at least one of the cylinders misfires, perform permission determination whether to execute the reignition process of the misfiring cylinder, on the basis of a damage diagnosis result based on an in-cylinder pressure of the misfiring cylinder, presence or absence of abnormality in a control device which performs combustion control and combustion diagnosis of the gas engine, an operational history related to the misfiring cylinder, and an operational state of the gas engine; and a reignition execution unit configured to execute the reignition process of the misfiring cylinder that is permitted by the permission determination to execute the reignition process.

Abstract: This command generation device generates a control command for a power conversion device which converts DC power outputted by a DC power supply device to AC power and supplies the same to a bus, and which converts AC power from the bus to DC power and supplies the same to the DC power supply device.

Abstract: A combined electric power generations' supply system includes an AC power generator that supplies power by off grid independent operation, a DC power supply device, an inverter that converts DC power output by the DC power supply device into AC power. The rotation calculation unit calculates a value relating to a rotation of a rotor when driving the virtual power generator according to an active power command based on a rotor model calculates a value relating to the rotation of the rotor of the virtual power generator and the active power command. The output determination unit determines values relating to an active power and a reactive power to be output to the inverter based on the calculated value relating to the rotation. The modulation control unit performs control of a pulse width modulation of the inverter based on the determined value relating to the active power and reactive power.

Abstract: A processing unit of a command generation device which is provided separately from a general-purpose inverter, performs following processing. A rotation calculation unit calculates a value relating to a rotation of a rotor of a virtual power generator when the virtual power generator is driven according to an active power command based on a rotor model that simulates a driving of the virtual power generator and calculates a value relating to the rotation of the rotor of the virtual power generator and an active power command. A target determination unit determines a target value of a voltage frequency and a target value of an active power based on the calculated value relating to the rotation. A command generation unit generates a control command for the inverter based on the determined target value of the voltage frequency and the target value of the active power.

Abstract: A rotation calculation unit calculates a rotation speed of a virtual generator on the basis of a rotor model to simulate driving of the virtual generator and calculates the rotation speed of the virtual generator. A target power determination unit determines target values of active power and reactive power of an inverter on the basis of the calculated rotation speed. A command generation unit generates a control command for the inverter on the basis of the determined target values of the active power and the reactive power.

Abstract: A drying device includes a first-heating rotator configured to contact a sheet twice from different directions, and at least three second-heating rotators each configured to contact the sheet once. The at least three second-heating rotators are in a conveyance path configured to guide the sheet to contact the first-heating rotator again after the sheet contacts and passes the first-heating rotator.

Abstract: The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine, isolating corresponding mRNA, and analyzing expression patterns in order to diagnose and treat various urothelial cancers. In particular, various expression patterns are analyzed through a unique diagnostic formula.

Abstract: The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine, isolating corresponding mRNA, and analyzing expression patterns in order to diagnose and treat various urothelial cancers. In particular, various expression patterns are analyzed through a unique diagnostic formula.

Abstract: A drying device includes a first-heating rotator configured to contact a sheet twice from different directions, and at least three second-heating rotators each configured to contact the sheet once. The at least three second-heating rotators are in a conveyance path configured to guide the sheet to contact the first-heating rotator again after the sheet contacts and passes the first-heating rotator.

Abstract: Provided herein are devices and methods for the capture or isolation of a biomarker from a biological sample. In several embodiments, the device comprises a loading region, a filter material, and a receiving region. In particular, in several embodiments, biological fluid is passed from the loading region through the filter material and into the receiving region, thereby resulting in capture or isolation of a biomarker.

Abstract: Disclosed are methods, device kits, and systems for improved quantification of mRNA from whole blood. More particularly, the devices and kites related thereto are useful for the controlled and repeatable ex vivo stimulation of whole blood.

Abstract: Embodiments of the invention relate generally to methods of identifying subjects likely to develop diabetes-associated damage to the nephron, or subjects in the early stages of diabetic nephropathy. In particular, several embodiments relate to quantification of diabetic nephropathy-associated RNA isolated from vesicles from patient urine samples is performed to compare a subject to a population having normal nephron function and/or to track progression of diabetic nephropathy in said subject over time.

Abstract: The present disclosure relates to methods of collecting exosomes and microvesicles (EMV) from urine and isolating corresponding mRNA in order to diagnose and treat acute kidney injury (AKI). In particular, certain embodiments relate to the method of capturing EMV from urine applied to a filter device that is capable of capturing EMV. Nucleic acids such as mRNA can be isolated from the EMV using an oligo(dT)-coated plate designed to accommodate the filter device and then used for further molecular analysis. Quantification of the collected nucleic acids may then be used in the diagnosis and/or treatment of IBD.

Abstract: The present invention relates to methods, compositions, and kits for detecting and quantitating exosomes and exosomal biomarkers and the use of exosomes and exosomal biomarkers in diagnostic and prognostic methods for various diseases and disorders.