Patents by Inventor Masayasu Kuwahara

Masayasu Kuwahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and reagent for gene sequence analysis
    Patent number: 8853373
    Abstract: Provided is a nucleic acid substrate which has nucleic acid substrate characteristics equivalent to those of dATP, has a low substrate specificity for luciferase, exerts no negative effect on enzymatic reactions such as a complementary-strand synthesis, and therefore is particularly suitable for the pyrosequencing method. As a nucleic acid substrate complementary to nucleotide T, a 7-substituted deoxyribonucleotide triphosphate whose 7-position of a purine group is modified by a substituent is used as a substitute for a nucleotide ?-thiotriphosphate analog.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: October 7, 2014
    Assignees: Hitachi, Ltd., National University Corporation Gunma University
    Inventors: Masayasu Kuwahara, Tomoharu Kajiyama, Hideki Kambara
  • METHOD AND REAGENT FOR GENE SEQUENCE ANALYSIS
    Publication number: 20120270210
    Abstract: Provided is a nucleic acid substrate which has nucleic acid substrate characteristics equivalent to those of dATP, has a low substrate specificity for luciferase, exerts no negative effect on enzymatic reactions such as a complementary-strand synthesis, and therefore is particularly suitable for the pyrosequencing method. As a nucleic acid substrate complementary to nucleotide T, a 7-substituted deoxyribonucleotide triphosphate whose 7-position of a purine group is modified by a substituent is used as a substitute for a nucleotide ?-thiotriphosphate analog.
    Type: Application
    Filed: August 10, 2010
    Publication date: October 25, 2012
    Inventors: Masayasu Kuwahara, Tomoharu Kajiyama, Hideki Kambara