Patents by Inventor Massachusetts Institute of Technology
Massachusetts Institute of Technology has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130240447Abstract: Hierarchical porous membranes suitable for use in oil/water separation processes are provided. The membranes described herein are particularly well suited for separating trace amounts of water (e.g., no greater than 3 wt % water content, no greater than 1 wt % water content, or 50-1000 ppm water) from oil. The membranes have a wide range of applications, including deep seep oil exploration, oil purification, and oil spill cleanup.Type: ApplicationFiled: February 28, 2013Publication date: September 19, 2013Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: Massachusetts Institute of Technology
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Publication number: 20130236764Abstract: Presented herein is a rechargeable lithium battery that includes a cathode, a liquid electrolyte, a solid electrolyte, and an anode. The anode is at least partially coated or plated with the solid electrolyte. The cathode may be porous and infiltrated by the liquid electrolyte. The cathode may also include a binder having a solid graft copolymer electrolyte (GCE). In certain embodiments, the liquid electrolyte is a gel that includes a PIL and a GCE. The battery achieves a high energy density and operates safely over a wide range of temperatures.Type: ApplicationFiled: March 7, 2013Publication date: September 12, 2013Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
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Publication number: 20130225969Abstract: A personal skin lesion scanner system that can facilitate early detection of changes in the appearance of a user's skin is described. The system includes a handheld device for home use, to record images of a user's skin, and software for analyzing the images. The system can automatically detect changes in the user's skin, such as changes in the size, shape, or color of a skin lesion, and alert the user if any changes are detected.Type: ApplicationFiled: February 25, 2013Publication date: August 29, 2013Inventor: Massachusetts Institute of Technology
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Publication number: 20130225671Abstract: Seizure disorders are treated by Ras inhibitors. In an embodiment, the Ras inhibitor includes a farnesyl transferase inhibitor. In another embodiment, the farnesyl transferase inhibitor includes a 3-hydroxy-3-methylglutaryl-Coenzyme A reductase inhibitor. In another embodiment, the 3-hydroxy-3-methylglutaryl-Coenzyme A reductase inhibitor is not a Ras inhibitor. Subjects having fragile X syndrome, autism, Angelman syndrome, Costello syndrome, cardio facio cutaneous syndrome, neurofibromatosis type I, Noonan syndrome and Coffin-Lowry syndrome that have seizure disorders can be treated.Type: ApplicationFiled: April 12, 2013Publication date: August 29, 2013Applicant: Massachusetts Institute of TechnologyInventor: Massachusetts Institute of Technology
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Publication number: 20130225432Abstract: The present invention is directed to novel high-throughput, low-cost, and flexible solution-based methods for RNA expression profiling, including expression of microRNAs and mRNAs.Type: ApplicationFiled: February 28, 2013Publication date: August 29, 2013Applicants: DANA-FARBER CANCER INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Massachusetts Institute of Technology, Dana-Farber Cancer Institute, Inc.
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Publication number: 20130213271Abstract: Cementitious compositions and methods of synthesis are disclosed. By decreasing the Ca-rich raw material in a cement composition, the content of Alite (Ca3SiO5) per ton of produced cement can be mitigated. Alite is the most energy-intensive and most polluting component among cement ingredients. By decreasing this component, the process can potentially reduce the environmental footprint and energy consumption by as much as 12% per ton of cement. In one embodiment, the average Ca/Si ratio in hardened cement paste can be reduced from ˜1.7 to ˜1.5. This corresponds to about a 12% reduction in Alite content per ton of produced cement. The cement compositions can also be characterized as solid-state cement hydrates including a plurality of silicate chains, the plurality of silicate chains including a plurality of dimers constituting at least about 60% of the plurality of silicate chains present in the solid-state cement hydrate, the plurality of dimers enhancing the strength of the solid-state cement hydrate.Type: ApplicationFiled: February 7, 2013Publication date: August 22, 2013Applicant: Massachusetts Institute of TechnologyInventor: Massachusetts Institute of Technology
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Publication number: 20130215485Abstract: In an illustrative implementation of this invention, an animated holographic display is created as follows: Multiple HPO holograms in the shape of horizontal strips are recorded on an H2 medium. These horizontal strips are vertically displaced from each other. An animated real image is displayed by sequentially illuminating these HPO holograms. In illustrative implementations of this invention, the vertical perspective of at least some adjacent HPO stripes are identical.Type: ApplicationFiled: March 15, 2013Publication date: August 22, 2013Applicant: Massachusetts Institute of TechnologyInventor: Massachusetts Institute of Technology
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Publication number: 20130208041Abstract: The disclosure relates to a method for depositing films on a substrate which may form part of an LED or other types of display. In one embodiment, the disclosure relates to an apparatus for depositing ink on a substrate. The apparatus includes a chamber for receiving ink; a discharge nozzle having an inlet port and an outlet port, the discharge nozzle receiving a quantity of ink from the chamber at the inlet port and dispensing the quantity of ink from the outlet port; and a dispenser for metering the quantity of ink from the chamber to the inlet port of the discharge nozzle; wherein the chamber receives ink in liquid form having a plurality of suspended particles and the quantity of ink is pulsatingly metered from the chamber to the discharge nozzle; and the discharge nozzle evaporates the carrier liquid and deposits the solid particles on the substrate.Type: ApplicationFiled: January 10, 2013Publication date: August 15, 2013Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: Massachusetts Institute of Technology
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Publication number: 20130207073Abstract: A light-emitting device comprising a population of quantum dots (QDs) embedded in a host matrix and a primary light source which causes the QDs to emit secondary light and a method of making such a device. The size distribution of the QDs is chosen to allow light of a particular color to be emitted therefrom. The light emitted from the device may be of either a pure (monochromatic) color, or a mixed (polychromatic) color, and may consist solely of light emitted from the QDs themselves, or of a mixture of light emitted from the QDs and light emitted from the primary source. The QDs desirably are composed of an undoped semiconductor such as CdSe, and may optionally be overcoated to increase photoluminescence.Type: ApplicationFiled: January 17, 2013Publication date: August 15, 2013Applicants: Lumileds Lighting US, LLC, Massachusetts Institute of TechnologyInventors: Massachusetts Institute of Technology, Lumileds Lighting US, LLC
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Publication number: 20130209668Abstract: The disclosure relates to a method for depositing films on a substrate which may form part of an LED or other types of display. In one embodiment, the disclosure relates to an apparatus for depositing ink on a substrate. The apparatus includes a chamber for receiving ink; a discharge nozzle having an inlet port and an outlet port, the discharge nozzle receiving a quantity of ink from the chamber at the inlet port and dispensing the quantity of ink from the outlet port; and a dispenser for metering the quantity of ink from the chamber to the inlet port of the discharge nozzle; wherein the chamber receives ink in liquid form having a plurality of suspended particles and the quantity of ink is pulsatingly metered from the chamber to the discharge nozzle; and the discharge nozzle evaporates the carrier liquid and deposits the solid particles on the substrate.Type: ApplicationFiled: December 6, 2012Publication date: August 15, 2013Applicant: Massachusetts Institute of TechnologyInventor: Massachusetts Institute of Technology
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Publication number: 20130208040Abstract: The disclosure relates to a method for depositing films on a substrate which may form part of an LED or other types of display. In one embodiment, the disclosure relates to an apparatus for depositing ink on a substrate. The apparatus includes a chamber for receiving ink; a discharge nozzle having an inlet port and an outlet port, the discharge nozzle receiving a quantity of ink from the chamber at the inlet port and dispensing the quantity of ink from the outlet port; and a dispenser for metering the quantity of ink from the chamber to the inlet port of the discharge nozzle; wherein the chamber receives ink in liquid form having a plurality of suspended particles and the quantity of ink is pulsatingly metered from the chamber to the discharge nozzle; and the discharge nozzle evaporates the carrier liquid and deposits the solid particles on the substrate.Type: ApplicationFiled: January 10, 2013Publication date: August 15, 2013Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: Massachusetts Institute of Technology
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Publication number: 20130204139Abstract: The systems, devices, and methods described herein provide for the estimation and monitoring of cerebrovascular system properties and intracranial pressure (ICP) from one or more measurements or measured signals. These measured signals may include central or peripheral arterial blood pressure (ABP), and cerebral blood flow (CBF) or cerebral blood flow velocity (CBFV). The measured signals may be acquired noninvasively or minimally-invasively. The measured signals may be used to estimate parameters and variables of a computational model that is representative of the physiological relationships among the cerebral flows and pressures. The computational model may include at least one resistive element, at least one compliance element, and a representation of ICP.Type: ApplicationFiled: January 25, 2013Publication date: August 8, 2013Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: Massachusetts Institute of Technology
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Publication number: 20130202959Abstract: Methods are provided for making bipolar electrochemical devices, such as batteries, using electrophoresis. A bipolar device is assembled by applying a field that creates a physical separation between two active electrode materials, without requiring insertion of a discrete separator film or electrolyte layer.Type: ApplicationFiled: January 25, 2013Publication date: August 8, 2013Applicants: A123 Systems, Inc., Massachusetts Institute of TechnologyInventors: Massachusetts Institute of Technology, A123 Systems, Inc.
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Publication number: 20130201330Abstract: Methods, systems and media are described for computer-assisted video surveillance. Methods may support detection of moving persons in video frames, extraction of features of the detected moving persons and identification of which detected moving persons are likely matches to a person of interest. Identification of the likely matches may be determined using an attribute-based search, and/or using a specific person-based search. The method may include using likely matches confirmed as images of the person of interest to reconstruct a path of the person of interest.Type: ApplicationFiled: January 18, 2013Publication date: August 8, 2013Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: Massachusetts Institute of Technology
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Publication number: 20130199600Abstract: The present invention generally relates to articles, systems, and methods relating to the thermal stability of nanostructured and/or microstructured materials.Type: ApplicationFiled: November 21, 2012Publication date: August 8, 2013Applicant: Massachusetts Institute of TechnologyInventor: Massachusetts Institute of Technology
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Publication number: 20130201329Abstract: Methods, systems and media are described for computer-assisted video surveillance. Methods may support detection of moving persons in video frames, extraction of features of the detected moving persons and identification of which detected moving persons are likely matches to a person of interest. Identification of the likely matches may be determined using an attribute-based search, and/or using a specific person-based search. The method may include using likely matches confirmed as images of the person of interest to reconstruct a path of the person of interest.Type: ApplicationFiled: January 18, 2013Publication date: August 8, 2013Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: Massachusetts Institute of Technology
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Publication number: 20130203733Abstract: The present invention is based, in part, on assays we conducted that revealed compounds that may be used to treat or prevent diseases characterized by an abnormal or undesirable association of one protein with another.Type: ApplicationFiled: December 20, 2012Publication date: August 8, 2013Applicants: Massachusetts Institute of Technology, The General Hospital CorporationInventors: The General Hospital Corporation, Massachusetts Institute of Technology
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Publication number: 20130202888Abstract: A fiber is provided, including a cladding material that is disposed along a longitudinal-axis fiber length. A plurality of spherical particles are disposed as a sequence along a longitudinal line parallel to the longitudinal fiber axis in at least a portion of the fiber length, and include a spherical particle material that is interior to the fiber cladding material and different than the fiber cladding material. To produce particles, a drawn fiber, having a longitudinal-axis fiber length and including at least one fiber core that has a longitudinal core axis parallel to the longitudinal fiber axis and that is internally disposed to at least one outer fiber cladding layer along the fiber length, is heated for a time that is sufficient to cause a fiber core to break-up into droplets sequentially disposed along the fiber core axis. Fiber cooling solidifies droplets into spherical particles interior to fiber cladding.Type: ApplicationFiled: March 14, 2013Publication date: August 8, 2013Applicants: University of Central Florida Research Foundation, Inc., MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Massachusetts Institute of Technology, University of Central Florida Research Foundation, Inc.
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Publication number: 20130195106Abstract: Techniques, devices, systems, and protocols are disclosed herein that relate to data transfer between communication nodes via multiple heterogeneous paths. In various embodiments, network coding may he used to improve data flow and reliability in a multiple path scenario. Transmission control protocol (TCP) may also be used within different paths to further enhance data transfer reliability. In some embodiments, multiple levels of network coding may be provided within a transmitter in a multiple path scenario, with one level being applied across ail paths and another being applied within individual paths.Type: ApplicationFiled: January 30, 2013Publication date: August 1, 2013Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventor: Massachusetts Institute of Technology
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Publication number: 20130198875Abstract: The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must he present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function. The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response.Type: ApplicationFiled: March 14, 2013Publication date: August 1, 2013Applicants: Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V., University of Massachusetts, Whitehead Institute for Biomedical Research, Massachusetts Institute of TechnologyInventors: Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V., Massachusetts Institute of Technology, Whitehead Institute of Biomedical Research, University of Massachusetts