Patents by Inventor Massachusetts Institute of Technology

Massachusetts Institute of Technology has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130197888
    Abstract: The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain dynamic three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth.
    Type: Application
    Filed: January 22, 2013
    Publication date: August 1, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130197318
    Abstract: A physiological measurement device or wearable device simulator includes a frame and a plurality of surfaces distributed within the frame. For each surface, a surface actuator links the surface of the frame. At least one of: i) force or position imparted by the surface on a physiological feature of a subject by the surface actuator; and ii) the force imparted by the physiological feature of the subject on the surface, can be employed to modulate the positions of the surfaces relative to each other independently of the forces imparted by or on those surfaces, thereby measuring the physiological feature of the subject or simulating a wearable device interface.
    Type: Application
    Filed: December 14, 2012
    Publication date: August 1, 2013
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130198205
    Abstract: An engine and method for tracking the influence of an entity operating within a social network are presented. A query containing social network content is received. A database for entries referencing the social network content is searched, and interactions between an entity participating within the social network and the social network content are identified. A dynamic interaction network (DIN) of a plurality of the entities is identified and a dynamic influence score for an entity in the query specific DIN is calculated.
    Type: Application
    Filed: January 30, 2013
    Publication date: August 1, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130197038
    Abstract: The invention is directed to a method of inducing angiogenesis at a site in an individual in need thereof comprising administering locally to the site an effective amount of one or more agents that induce hypoxia induced factor 1? (HIF-1?). In another aspect, the invention is directed to a method of inducing angiogenesis at a site in an individual in need thereof comprising administering locally to the site an effective amount of one or more agents that induce hypoxia induced factor 1? (HIF-1?) and one or more lysophospholipids. In addition, the invention is directed to methods of generating prevascularized tissue, methods of generating a vascular network in a device and compositions thereof.
    Type: Application
    Filed: January 16, 2013
    Publication date: August 1, 2013
    Applicants: Massachusetts Institute of Technology, National University of Singapore
    Inventors: National University of Singapore, Massachusetts Institute of Technology
  • Publication number: 20130197162
    Abstract: Method for connecting two portions of a first electrically conducting polymer with a second polymer. The method includes disposing a solution of a second polymer in a solvent to be in contact with the two portions of the first electrically conducting polymer and allowing the solvent to evaporate leaving the second polymer joining the two portions of the first polymer. The second polymer may be doped to improve its conductivity.
    Type: Application
    Filed: February 13, 2013
    Publication date: August 1, 2013
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130198372
    Abstract: A distributed inexact Newton-type second order method for Network Utility maximization problems is provided. Such methods are capable of achieving superlinear convergence rates (in primal iterates) to some error neighborhood, can be implemented in a decentralized manner using a matrix splitting scheme, and is compatible with current information exchange mechanisms.
    Type: Application
    Filed: December 17, 2012
    Publication date: August 1, 2013
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130197069
    Abstract: The invention relates to methods and products for treating emotional disorders such as stress induced emotional disorders, as well as related assays and kits. Methods include administering to a subject an effective amount of an agent for targeting the Rac1, Cdk5, p35, PAK-1 pathway to treat the emotional disorder. The agent for targeting the Rac1, Cdk5, p35, PAK-1 pathway may be, for instance, a Rac-1 inhibitor, a Cdk5 inhibitor, a PAK-1 activator, or p35 mobilizing agent.
    Type: Application
    Filed: March 27, 2013
    Publication date: August 1, 2013
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventor: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
  • Publication number: 20130190890
    Abstract: The present invention provides, among other things, multilayer film coating compositions, coated substrates and methods thereof. In some embodiments, a structure includes a first and second layer-by-layer film disposes on a substrate, the structure being characterized in that layer-by-layer removal of at least the second film releases at least one polypeptide, and also may permit release of ions from the ceramic material so that a synergetic effect of the osteoinduction and osteoconduction of the structure is achieved.
    Type: Application
    Filed: January 22, 2013
    Publication date: July 25, 2013
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130191084
    Abstract: The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain dynamic three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth.
    Type: Application
    Filed: January 22, 2013
    Publication date: July 25, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130187051
    Abstract: A photon detection system with improved high-speed performance. An array of photon detectors is provided, providing transient responses that indicate both a time and a location of photon detection. Each photon detector may use a superconducting nanowire, arranged as part of a resonant cell to have a unique resonant frequency. Upon detection of even a single photon, a resonant cell may create a transient response comprising its unique resonant frequency. The transient responses may be combined on a single readout line, allowing identification of the photon detection location based on a detected frequency component read out. The electrical properties within resonant cells, as well as the connections between different resonant cells, may be configured to produce different transient responses. For example, resonant cells may be configured to produce a transient response having multiple pulses, which may separately indicate a time and a location of a photon detection.
    Type: Application
    Filed: October 2, 2012
    Publication date: July 25, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130186768
    Abstract: The present invention generally relates to articles, devices, systems, and methods relating to the storage of solar energy and/or solar energy utilization. In some embodiments, the articles, devices, and systems may be used to carry out photocatalytic reactions, for example, the photocatalytic production of oxygen and/or hydrogen gases from water.
    Type: Application
    Filed: January 4, 2013
    Publication date: July 25, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130184444
    Abstract: A water soluble nanoparticle can include a ligand of formula (I). The ligand can provide zwitterionic character and can provide water solubility, small hydrodynamic diameter, chemical stability, and the capability to modify the nanoparticle with additional functional moieties such as a small molecule, nucleic acid, or protein.
    Type: Application
    Filed: December 15, 2012
    Publication date: July 18, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130184846
    Abstract: The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain dynamic three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth.
    Type: Application
    Filed: January 22, 2013
    Publication date: July 18, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130181962
    Abstract: Embodiments of the present invention provide for an array, and corresponding method of forming an array, that includes a plurality of light emitting devices. The light emitting devices are disposed over a substrate, and a photodetector detects light emitted through the substrate from the light emitting devices. Further, a substantially constant brightness may be maintained in a plurality of light emitting devices disposed over the upper surface of a substrate in an array. Light emitted through the substrate from each of the light emitting devices is measured, and the voltage level applied to each of the light emitting devices is varied to maintain a substantially constant brightness level of light emitted from the light emitting devices.
    Type: Application
    Filed: March 4, 2013
    Publication date: July 18, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130182882
    Abstract: The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain dynamic three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth.
    Type: Application
    Filed: January 22, 2013
    Publication date: July 18, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130181541
    Abstract: Disclosed is an apparatus for use in wireless energy transfer, which includes a first resonator structure configured to transfer energy non-radiatively with a second resonator structure over a distance greater than a characteristic size of the second resonator structure. The non-radiative energy transfer is mediated by a coupling of a resonant field evanescent tail of the first resonator structure and a resonant field evanescent tail of the second resonator structure.
    Type: Application
    Filed: March 8, 2013
    Publication date: July 18, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130178568
    Abstract: A surface can be coated with a liquid repellent coating. Materials for making the liquid repellent coating (e.g., a fingerprint resistant coating) can be selected on the basis of surface energy considerations, such as a receding surface energy. The materials can include a polymer and a liquid repelling material, for example, poly(ethyl methacrylate) and a fluorinated silsesquioxane such as fluorodecyl POSS.
    Type: Application
    Filed: January 4, 2013
    Publication date: July 11, 2013
    Applicants: The United States of America as Represented by the Secretary of the Air Force, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Massachusetts Institute of Technology, The United States of America as Represented by the Secretary of the Air Force
  • Publication number: 20130178632
    Abstract: One aspect of the present invention relates to ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in various transition-metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition-metal-catalyzed reactions, including the range of suitable substrates, number of catalyst turnovers, reaction conditions, and efficiency. For example, improvements have been realized in transition metal-catalyzed: aryl amination reactions; aryl amidation reactions; Suzuki couplings; and Sonogashira couplings. In certain embodiments, the invention relates to catalysts and methods of using them that operate in aqueous solvent systems.
    Type: Application
    Filed: February 15, 2013
    Publication date: July 11, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130179120
    Abstract: The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements of hardware, and processing techniques that can be used to capture these thickness measurements and obtain dynamic three-dimensional images of the target surface in a variety of imaging contexts. This includes general techniques for imaging interior/concave surfaces as well as exterior/convex surfaces, as well as specific adaptations of these techniques to imaging ear canals, human dentition, and so forth.
    Type: Application
    Filed: January 22, 2013
    Publication date: July 11, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130177607
    Abstract: Nanocells allow the sequential delivery of two different therapeutic agents with different modes of action or different pharmacokinetics. A nanocell is formed by encapsulating a nanocore with a first agent inside a lipid vesicle containing a second agent. The agent in the outer lipid compartment is released first and may exert its effect before the agent in the nanocore is released. The nanocell delivery system may be formulated in pharmaceutical composition for delivery to patients suffering from diseases such as cancer, inflammatory diseases such as asthma, autoimmune diseases such as rheumatoid arthritis, infectious diseases, and neurological diseases such as epilepsy. In treating cancer, a traditional antineoplastic agent is contained in the outer lipid vesicle of the nanocell, and an antiangiogenic agent is loaded into the nanocore. This arrangement allows the antineoplastic agent to be released first and delivered to the tumor before the tumor's blood supply is cut off by the antianiogenic agent.
    Type: Application
    Filed: January 18, 2013
    Publication date: July 11, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology