Abstract: Method for functional imaging of the brain, comprising the following steps: (a) a brain is imaged by ultrasound imaging in order to obtain a vascular image to be studied (IVO), (b) the vascular image to he studied (IVO) is compared automatically, by shape recognition, with a cerebral vascular atlas (AV), and the vascular image to be studied (IVO) is thus located in the cerebral vascular atlas (AV), (c) a cerebral functional atlas (AF) corresponding to said cerebral vascular atlas (AV) and comprising cerebral functional zones (1c) located in this cerebral vascular atlas (AV) is used in such a way as to identify cerebral functional zones (1e) on the vascular image to be studied (IVO).

Abstract: A method for characterizing an anisotropic soft medium (C) including fibers and having an outer surface (1), by observing in different propagation directions, the propagation of a divergent shear wave from a central area (10) in the anisotropic soft medium. A propagation parameter of the shear wave is inferred therefrom in each of the propagation directions, and then a direction of the fibers of the anisotropic soft medium, a rheological elasticity parameter are determined in a direction perpendicular to the fibers and a rheological elasticity parameter in the direction of the fibers.

Abstract: The invention relates to an acoustic-electric imaging method, which includes: a measurement step during which incident ultrasonic waves having different wavefronts are emitted in a medium 1 to be imaged, and at least one electric sensor is used to capture raw electric signals Erawl(t) respectively during the propagation of the incident waves; a step of forming an image, during which an image of the medium including an electric current map is determined from the raw electric signals Erawl(t).

Abstract: A Method for measuring heart contractility of a patient, in which a mechanical shear wave is propagated through the heart and observation of the propagation leads to determine a shear wave propagation parameter representative of the elasticity of the heart is disclosed. The value of the propagation parameter at the end of a systole is sampled, which leads to a parameter representative of the end systolic elastance.

Abstract: Device for focusing pulses comprising at least emitting means comprising a network of transducers, these emitting means being adapted to make the network of transducers emit, into a reflective cavity, at least one wave focused onto at least one target point of a target medium. The reflective cavity comprises a multi-scattering medium adapted to cause multiple scattering of said wave.

Abstract: A system and method for detecting electromechanical wave propagation within a body structure of a patient in a series of image frames representing movement the body structure. Image data is acquired comprising a series of image frames corresponding to the movement of a body structure. A correlation calculation is performed on the image frames to generate a displacement map representing the relative displacement between the first and second image frames. A video is generated comprising a series of displacement maps. The parameters of movement of the body structure are detected by analysis of the displacement maps. The image acquisition may detect the movement of the body structure without inducing such movement.

Abstract: A system and method for detecting electromechanical wave propagation within a body structure of a patient in a series of image frames representing movement the body structure. Image data is acquired comprising a series of image frames corresponding to the movement of a body structure. A correlation calculation is performed on the image frames to generate a displacement map representing the relative displacement between the first and second image frames. A video is generated comprising a series of displacement maps. The parameters of movement of the body structure are detected by analysis of the displacement maps. The image acquisition may detect the movement of the body structure without inducing such movement.

Abstract: The invention concerns a device (1) for the insonification of an environment or medium, which is designed to generate a beam of focussed waves around a point in a so-called focus zone (20), used for imaging the medium or changing the properties of the medium, with the insonification device (1) having an intrinsic or extrinsic support structure on which is installed a network of a predetermined number of ultrasound transducers (12) that are designed to be controlled independently for generation of the focussed wave beam. According to the invention, the transducers (12) used for the generation of the focussed wave beam are located in a homogeneous spatial distribution along at least two concentric spirals (11) that are wound onto a three-dimensional concave area (10) whose shape and size are chosen to allow optimal focusing of the beam at a predetermined focal length, and whose concave side is oriented toward the focus zone (20).

Abstract: The invention relates to an insonification device (100) comprising a plurality of elementary ultrasonic transducers (110) each comprising at least one electro-acoustic element (111) and distributed on a chassis (120, 140) so that the electro-acoustic elements (111) are distributed on a so-called front surface (120?) of the device (100) intended to be placed facing the medium to be insonified. According to the invention, as each transducer (110) comprises a longitudinal body (113) made in a heat conducting material at the so-called front end of which the electro-acoustic element (111) is placed, the chassis (120, 140) comprises a sealed cooling chamber (130) placed behind the front surface (120?), crossed by the bodies of the transducers (113) and intended to be gone through by a coolant fluid flow.

Abstract: The invention concerns a method for optimizing the focusing of waves in a zone of interest of a medium, with the waves being emitted by a network of sources to the medium through an aberration-inducing element that introduces an initially indeterminate phase shift. The method according to the invention proposes to use M?1 successive modifications of the emitted wave, each giving rise to a perturbation. According to the invention, the M perturbations are measured in the zone of interest at each modification of the phase and/or amplitude distributions, and these measurements are used to deduce optimal focusing characteristics to maximize the perturbation induced in the zone of interest.

Abstract: The present invention relates to a method for generating mechanical waves within a viscoelastic medium (11) comprising a step of generating an acoustic radiation force (15) within the viscoelastic medium (11) by application of acoustic waves focused on an interface (13) delimiting two zones (11, 14) having distinct acoustic properties.

Abstract: The invention concerns a device (1) for the insonification of an environment or medium, which is designed to generate a beam of focussed waves around a point in a so-called focus zone (20), used for imaging the medium or changing the properties of the medium, with the insonification device (1) having an intrinsic or extrinsic support structure on which is installed a network of a predetermined number of ultrasound transducers (12) that are designed to be controlled independently for generation of the focussed wave beam. According to the invention, the transducers (12) used for the generation of the focussed wave beam are located in a homogeneous spatial distribution along at least two concentric spirals (11) that are wound onto a three-dimensional concave area (10) whose shape and size are chosen to allow optimal focusing of the beam at a predetermined focal length, and whose concave side is oriented toward the focus zone (20).

Abstract: Method for measuring a physical parameter in soft tissues of a mammal, in which a mechanical shear wave is propagated through the soft tissues and observation of the propagation leads to determine values of a shear wave propagation parameter. The physical parameter is computed on the basis of these values.

Abstract: The invention relates to an insonification device (100) comprising a plurality of elementary ultrasonic transducers (110) each comprising at least one electro-acoustic element (111) and distributed on a chassis (120, 140) so that the electro-acoustic elements (111) are distributed on a so-called front surface (120?) of the device (100) intended to be placed facing the medium to be insonified. According to the invention, as each transducer (110) comprises a longitudinal body (113) made in a heat conducting material at the so-called front end of which the electro-acoustic element (111) is placed, the chassis (120, 140) comprises a sealed cooling chamber (130) placed behind the front surface (120?), crossed by the bodies of the transducers (113) and intended to be gone through by a coolant fluid flow.

Abstract: A Method for measuring heart contractility of a patient, in which a mechanical shear wave is propagated through the heart and observation of the propagation leads to determine a shear wave propagation parameter representative of the elasticity of the heart is disclosed. The value of the propagation parameter at the end of a systole is sampled, which leads to a parameter representative of the end systolic elastance.

Abstract: The invention concerns a method for optimizing the focusing of waves in a zone of interest of a medium, with the waves being emitted by a network of sources to the medium through an aberration-inducing element that introduces an initially indeterminate phase shift. The method according to the invention proposes to use M?1 successive modifications of the emitted wave, each giving rise to a perturbation. According to the invention, the M perturbations are measured in the zone of interest at each modification of the phase and/or amplitude distributions, and these measurements are used to deduce optimal focusing characteristics to maximize the perturbation induced in the zone of interest.

Abstract: A system and method for opening the blood-brain barrier in the brain of a subject is disclosed. In some embodiments, a region of the brain of a subject is targeted for opening; and a focused ultrasound beam is applied through the skull of the subject to the targeted region to open the blood-brain barrier in the brain of the subject.

Abstract: The present invention relates to a method for generating mechanical waves within a viscoelastic medium (11) comprising a step of generating an acoustic radiation force (15) within the viscoelastic medium (11) by application of acoustic waves focussed on an interface (13) delimiting two zones (11, 14) having distinct acoustic properties.

Abstract: A system and method for detecting electromechanical wave propagation within a body structure of a patient in a series of image frames representing movement the body structure. Image data is acquired comprising a series of image frames corresponding to the movement of a body structure. A correlation calculation is performed on the image frames to generate a displacement map representing the relative displacement between the first and second image frames. A video is generated comprising a series of displacement maps. The parameters of movement of the body structure are detected by analysis of the displacement maps. The image acquisition may detect the movement of the body structure without inducing such movement.