Patents by Inventor Matt Ewert

Matt Ewert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BLOOD ANALYSIS
    Publication number: 20160341747
    Abstract: Provided herein are kits, devices and methods related to blood analysis. In some aspects, kits, devices and methods related to analyzing unprocessed and processed blood are provided, e.g., by processing blood with enzymes and measuring transmittance of light passed through the processed blood and as well as through unprocessed blood. Such kits, devices and methods are useful, e.g., for identifying the presence or absence of infection, and also the type of infection, if present.
    Type: Application
    Filed: December 18, 2015
    Publication date: November 24, 2016
    Applicant: Imigene, Inc.
    Inventor: Matt Ewert
  • INFECTION MEDIATED FOAM DISSOLUTION RATE MEASUREMENT
    Publication number: 20150322477
    Abstract: The subject invention concerns methods and materials for determining the presence or absence of bacterial or fungal infection in a blood sample. In one embodiment, a method of the invention comprises exposing an anticoagulant treated blood sample to freezing the sample to a solid, followed by thawing of the sample and then agitation of the sample to develop foam and then observing the rate that foam dissolves.
    Type: Application
    Filed: April 15, 2015
    Publication date: November 12, 2015
    Inventors: Matt Ewert, Adam Merritt
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8962243
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: February 24, 2015
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8927243
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: January 6, 2015
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8916698
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: December 23, 2014
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8815502
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: August 26, 2014
    Assignee: University of South Florida
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8785176
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: July 22, 2014
    Assignee: University of South Florida
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8759479
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: June 24, 2014
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8735090
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: May 27, 2014
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • POST PROTEIN HYDROLYSIS REMOVAL OF A POTENT RIBONUCLEASE INHIBITOR AND THE ENZYMATIC CAPTURE OF DNA
    Publication number: 20140093944
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Application
    Filed: March 28, 2013
    Publication date: April 3, 2014
    Applicant: University of South Florida
    Inventor: Matt Ewert
  • Early detection of pathogens in blood
    Patent number: 8617839
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: December 31, 2013
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • INHIBITOR LEACHING RESISTANT NUCLEIC ACID STORAGE REAGENT
    Publication number: 20130330729
    Abstract: The invention provides compositions and methods related to a nucleic acid storage reagent.
    Type: Application
    Filed: October 18, 2012
    Publication date: December 12, 2013
    Applicant: Imigene, Inc.
    Inventor: Matt Ewert
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8592200
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: November 26, 2013
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8574866
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: November 5, 2013
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • POST PROTEIN HYDROLYSIS REMOVAL OF A POTENT RIBONUCLEASE INHIBITOR AND THE ENZYMATIC CAPTURE OF DNA
    Publication number: 20130236920
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Application
    Filed: December 21, 2012
    Publication date: September 12, 2013
    Applicant: University of South Florida
    Inventor: Matt Ewert
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 8465966
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: June 18, 2013
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • INHIBITOR LEACHING RESISTANT NUCLEIC ACID STORAGE REAGENT
    Publication number: 20130102005
    Abstract: The invention provides compositions and methods related to a nucleic acid storage reagent.
    Type: Application
    Filed: October 18, 2012
    Publication date: April 25, 2013
    Applicant: Imigene, Inc.
    Inventor: Matt Ewert
  • Post Protein Hydrolysis Removal of a Potent Ribonuclease Inhibitor and the Enzymatic Capture of DNA
    Publication number: 20120164714
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Application
    Filed: May 8, 2008
    Publication date: June 28, 2012
    Applicant: University of South Florida
    Inventors: Matt Ewert, Phil Amuso, Andrew Cannons
  • EARLY DETECTION OF PATHOGENS IN BLOOD
    Publication number: 20120034614
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Application
    Filed: August 11, 2011
    Publication date: February 9, 2012
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: MATT EWERT, Philip Amuso, Andrew Cannons
  • Early detection of pathogens in blood
    Patent number: 7998699
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: August 16, 2011
    Assignee: University of South Florida
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons