Patents by Inventor Matt Ewert

Matt Ewert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Early detection of pathogens in blood
    Patent number: 7993870
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: August 9, 2011
    Assignee: University of South Florida
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons
  • Infection Mediated Foam Dissolution Rate Measurement
    Publication number: 20110059460
    Abstract: The subject invention concerns methods and materials for determining the presence or absence of bacterial or fungal infection in a blood sample. In one embodiment, a method of the invention comprises exposing an anticoagulant treated blood sample to freezing the sample to a solid, followed by thawing of the sample and then agitation of the sample to develop foam and then observing the rate that foam dissolves.
    Type: Application
    Filed: March 3, 2009
    Publication date: March 10, 2011
    Inventor: Matt Ewert
  • Early Detection of Pathogens in Blood
    Publication number: 20090305383
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Application
    Filed: April 1, 2009
    Publication date: December 10, 2009
    Applicant: University of South Florida
    Inventors: MATT EWERT, Philip Amuso, Andrew Cannons
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Patent number: 7416843
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: January 14, 2005
    Date of Patent: August 26, 2008
    Assignee: University of South Florida
    Inventors: Matt Ewert, Phil Amuso, Andrew Cannons
  • Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
    Publication number: 20050277130
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Application
    Filed: January 14, 2005
    Publication date: December 15, 2005
    Inventors: Matt Ewert, Phil Amuso, Andrew Cannons
  • Early Detection of Pathogens in Blood
    Publication number: 20050014128
    Abstract: The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
    Type: Application
    Filed: August 15, 2003
    Publication date: January 20, 2005
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Matt Ewert, Philip Amuso, Andrew Cannons