Abstract: According to examples, a system for measuring polarization dependent loss (PDL) for a device-under-test (DUT) may include a tunable laser, a polarization element and a power meter. The tunable laser may emit an optical signal to sweep across an optical band at a constant rate. The polarization element may scramble polarizations states of the optical signal emitted from the tunable laser. The power meter may take power measurements associated with the optical signal emitted from the tunable laser, wherein the power measurements from the power meter are used to determine a maximum insertion loss (IL) and a minimum insertion loss (IL) associated with the device-under-test (DUT). An average insertion loss (IL) and a polarization dependent loss (PDL) for the device-under-test (DUT) may be calculated based on the maximum insertion loss (IL) and the minimum insertion loss (IL) associated with the device-under-test (DUT).

Abstract: A method of changing a virtual world of a computer-implemented game based on real-world locations of players of the computer-implemented game is disclosed. A presence of a player of the computer-implemented game is detected at a physical location. A presence of an additional player of the computer-implemented game is detected at the physical location based on a communication received from the player of the computer-implemented game. An aspect of the virtual world of the computer-implemented game is changed based on the detecting of the presence of the player at the physical location and the detecting of the presence of the additional player of the computer-implemented game at the physical location.

Abstract: Provided herein are novel anti-CD28 x anti-PSMA antibodies and methods of using such antibodies for the treatment of PSMA-associated cancers. Subject anti-CD28 x anti-PSMA antibodies are capable of agonistically binding to CD28 costimulatory molecules on T cells and PSMA on tumor cells. Thus, such antibodies selectively enhance anti-tumor activity at tumor sites while minimizing peripheral toxicity. The subject antibodies provided herein are particularly useful in combination with other anti-cancer therapies (e.g., anti-CD3 x anti-PSMA antibodies) for the treatment of prostate cancers.

Abstract: A motorised measurement arm apparatus for a machine tool includes a base for attachment to the machine tool and an arm member extending from the base for holding one or more sensors. The arm member is moveable relative to the base between a stowed position and an operative position, the operative position being defined by engagement of a mechanical stop arrangement. The apparatus also has a motor for moving the arm member relative to the base and a motor controller for energising the motor to move the arm member relative to the base. The motor controller is configured to energise the motor when the arm member is in the operative position to maintain engagement of the mechanical stop arrangement. An operative position having improved repeatability is thus obtained.

Abstract: The disclosure herein describes training a document recommendation model using loss data generated from a linear score difference vector. A training data entry is provided including a query and a set of candidate documents. A document recommendation model generates a set of document prediction scores indicative of a likelihood that the candidate documents are responses to the query and a pairwise score difference matrix is generated using the set of document prediction scores. The pairwise score difference matrix is transformed into a score difference vector using a correct document vector that indicates a correct document among the set of candidate documents. Loss data of the document recommendation model is generated using the score difference vector and the document recommendation model is adjusted using the calculated loss data. Training the document recommendation model based on the linear score difference vector reduces resource usage when compared to training with a difference matrix.

Abstract: Provided herein are variant human IL18 proteins including proteins and constructs including such. Various variant IL18 proteins with modifications to reduce heterogeneity and/or reduce affinity/potency and/or improve stability and/or improve production yield are also described. Also provided are IL18-Fc fusion proteins that include an empty-Fc domain and an IL18 protein connected to another Fc domain. Also provided herein are IL18Fc fusion proteins that bind CD3 and a tumor target antigen.

Abstract: Aspects of the present disclosure are directed to creating interactive avatars that can be pinned as world-locked artificial reality content. Once pinned, an avatar can interact with the environment according to contextual queues and rules, without active control by the avatar owner. An interactive avatar system can configure the avatar with action rules, visual elements, and settings based on user selections. Once an avatar is configured and pinned to a location by an avatar owner, when other XR devices are at that location, a central system can provide the avatar (with its configurations) to the other XR device. This allows a user of that other XR device to discover and interact with the avatar according to the configurations established by the avatar owner.

Abstract: A variable optical attenuator (VOA) may include an input collimator with an input fiber connected on one side and an output collimator with an output fiber connected on one side, where the collimators are on a same surface of a VOA enclosure. A retroreflector may receive a light beam from the input collimator and reflect the light beam to the output collimator. The VOA may include an attenuation element positioned between the input collimator and the retroreflector and/or another attenuation element positioned between the retroreflector and the output collimator to provide variable attenuation to the light beam. The attenuation elements may be moved to set an attenuation level by one or more adjustment elements such as a miniature motor. The attenuation element may include a gradient index (GRIN) element, a polarizer, a neutral density filter, or a wavelength tunable filter.

Abstract: Provided herein are novel antigen binding domains and antibodies (e.g., heterodimeric antibodies) that bind Prostate Specific Membrane Antigen (PSMA). In exemplary embodiments, the anti-PSMA antibodies also bind CD3. Such antibodies that bind PSMA and CD3 are useful, for example in the treatment of PSMA-related cancer.

Abstract: A method for adjusting an exposure level of an image sensor. The method comprises receiving intensity values of a current image captured by the image sensor, the image sensor having an initial exposure level when the current image is captured. The method comprises determining an intensity status based on comparing at least one characteristic of at least the current intensity values to one or more criteria. The method comprises selecting an exposure convergence mode, from a plurality of exposure convergence modes, based on the intensity status. The method comprises calculating, based on the current intensity values and the exposure convergence mode, a new exposure level for use by the image sensor in capturing a subsequent image.

Abstract: A skateboard deck that is both stiff in one dimension and flexible in another dimension is disclosed. The deck includes an elongated body characterized by a longitudinal axis, a plurality of ribs, and a plurality of apertures. The plurality of ribs are long, narrow beams oriented substantially parallel to the longitudinal axis and integral with the bottom of the elongated body. The plurality of apertures are distributed in a plurality of rows also oriented substantially parallel to the longitudinal axis. The ribs and rows of apertures are interposed in an alternating pattern across the width of the deck. The resulting deck is stiff in the longitudinal direction yet flexible with respect to rotation about the longitudinal axis. The deck is therefore flexible enough to enable the front and rear trucks to rotate with respect to one another while still being rigid enough to withstand the weight of the rider.

Abstract: A method for processing an image captured by an image sensor. The method comprises receiving first pre-tonemapped intensity values of a first image captured by the image sensor. The method comprises applying a first tonemapping function having a first tonemapping strength to the first pre-tonemapped intensity values to generate first tonemapped intensity values. The method comprises receiving second pre-tonemapped intensity values of a second image captured by the image sensor, the second image captured subsequent to the first image. The method comprises, based on a difference between the first tonemapped intensity values and a target for the first tonemapped intensity values, determining a second tonemapping function having a second tonemapping strength. The method comprises applying the second tonemapping function to the second pre-tonemapped intensity values to generate second tonemapped intensity values.

Abstract: A method for processing an image. The method comprises receiving intensity values for each of a plurality of images captured by an image sensor during a detection window. The method comprises identifying, using the intensity values, one or more transitions occurring during the detection window, the one or more transitions each comprising a transition between an image in which a maximum clipping criterion is not satisfied and an image in which the maximum clipping criterion is satisfied. The method comprises, based on the identified transitions, at least one of: adjusting an exposure level of the image sensor; and determining a tonemapping function having a tonemapping strength, and applying the tonemapping function to the intensity values of a current image to generate tonemapped intensity values, wherein the image sensor has a current exposure level when the current image is captured.

Abstract: A microscope may receive a fiber optic connector via a connector adapter of the microscope, wherein the connector adapter includes an opening and a shaped reflective surface surrounding the opening. The microscope may align a ferrule of the fiber optic connector with the opening of the connector adapter of the microscope, wherein the ferrule includes a ferrule endface. The microscope may transmit light onto the shaped reflective surface and may receive reflected light from the ferrule endface and with a camera of the microscope.

Abstract: Aspects of the present disclosure are directed to creating interactive avatars that can be pinned as world-locked artificial reality content. Once pinned, an avatar can interact with the environment according to contextual queues and rules, without active control by the avatar owner. An interactive avatar system can configure the avatar with action rules, visual elements, and settings based on user selections. Once an avatar is configured and pinned to a location by an avatar owner, when other XR devices are at that location, a central system can provide the avatar (with its configurations) to the other XR device. This allows a user of that other XR device to discover and interact with the avatar according to the configurations established by the avatar owner.

Abstract: A viewport for a combustion zone includes an inner casing having a flange extending into the combustion zone. A first layer of ceramic fiber insulation is exterior to the inner casing. A middle casing includes two panes of quartz glass separated by traverse plates. A second layer of ceramic fiber insulation is exterior to the middle casing. An outer casing is positioned to the exterior of the second layer of insulation. The middle casing includes L-shaped ledges having third and fourth layers of ceramic insulation. The panes of glass are each positioned between layers of insulation and the insulation positioned in the L-shaped ledges. The viewport is modular enabling the separation of the first layer of insulation, the middle casing, the second layer of insulation and the outer casing from the combustion zone for maintenance or repair. The viewport minimizes heat migration to the outer casing during use.

Abstract: A system for monitoring a usage of rolled or stacked disposable sanitary product in a predetermined location or facility and providing information associated with said usage to one or more users, comprising: (a) one or more optical sensors mounted at respective locations associated with where the product is dispensed and configured to monitor a diameter of the roll or height of the stack and transmit data associated therewith; and (b) one or more receivers configured to receive and transmit said data to one or more databases for storage, processing, analysis and/or user notification regarding product usage.

Abstract: A systemic dual motor framing for a watercraft is provided as is the overall system. The systemic dual motor framing is movable between a folded condition and an unfolded condition for attaching with the assistance of strapping to a stern of the watercraft, sleeve-like, either by sliding over the stern end or strapping around the stern. In the unfolded condition, the systemic dual motor framing facilities the strapping while maintaining a motor on each side of the watercraft, wherein the two motors can be selectively powered in conjunction remotely.

Abstract: Provided herein are novel anti-CD28×anti-PSMA antibodies and methods of using such antibodies for the treatment of PSMA-associated cancers. Subject anti-CD28×anti-PSMA antibodies are capable of agonistically binding to CD28 costimulatory molecules on T cells and PSMA on tumor cells. Thus, such antibodies selectively enhance anti-tumor activity at tumor sites while minimizing peripheral toxicity. The subject antibodies provided herein are particularly useful in combination with other anti-cancer therapies (e.g., anti-CD3×anti-PSMA antibodies) for the treatment of prostate cancers.

Abstract: The invention relates to a process for the production of ethylene by oxidative dehydrogenation (ODH) of ethane, comprising: a) supplying ethane and oxygen to a first ODH zone which is formed by multiple reactor tubes containing a mixed metal oxide ODH catalyst bed; b) contacting the ethane and oxygen with the catalyst resulting in multiple effluent streams, wherein the multiple reactor tubes are cooled by a coolant; c) mixing at least a portion of the multiple effluent streams from step b) resulting in a mixture comprising ethylene, unconverted ethane and unconverted oxygen; d) supplying at least a portion of the mixture from step c) to a second ODH zone containing a mixed metal oxide ODH catalyst bed; e) contacting at least a portion of the mixture from step c) with the catalyst in the second ODH zone resulting in a stream comprising ethylene and unconverted ethane.