Abstract: Systems and methods are provided to create training data, validate, deploy and test artificial intelligence (AI) systems in a virtual development environment, incorporating virtual spaces, objects, machinery, devices, subsystems, and actual human action and behavior.

Abstract: A series of fused pentacyclic imidazole derivatives, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. In particular, the present invention is concerned with 6, 7-dihydro-7, 14-methanobenzimidazo[1, 2-b][2,5]benzodiazocin-5(14H)-one derivatives and analogs thereof.

Abstract: A metal cabinet for housing medical waste disposal containers includes a locking mechanism for controlled access into the metal cabinet and a cut-out or window integrated into the metal cabinet for visualization of a portion of the medical waste disposal container(s) housed therein.

Abstract: A saw blade includes an elongated body with a working edge extending along a longitudinal axis. A first strip composed of carbide or cermet and including at least one first full cutting tooth is coupled to a first portion of the working edge by a first weld fusion zone composed of a ductile material. The first strip is set in a first direction at a first angle out of a plane of the body by a first bend in the first weld fusion zone. A second strip composed of carbide or cermet and including at least one second full cutting tooth is coupled to a second portion of the working edge by a second weld fusion zone composed of a ductile material. The second strip is set in a second direction, opposite the first direction, at a second angle out of the plane of the body by a second bend in the second weld fusion zone.

Abstract: A step drill bit includes a cutting head portion with a rear end coupled to a shank portion. The cutting head portion incudes a front cutting tip, a plurality of steps of progressively increasing diameter from the cutting head to the rear end portion. Each step includes a conical tapered portion that flares radially outward from the axis and a generally cylindrical portion that extends axially rearward from the tapered portion. A flute extends through the steps generally parallel to or helically relative to the axis. Primary and secondary cutting edges are formed at junctions between the tapered portions and the generally cylindrical portions and the flute. A depth stop flange extends radially outward from a rearmost step and has a diameter greater than the diameter of the cylindrical portion of the rearmost step. A deburring recess is disposed within or between one of the steps and includes a deburring edge at a junction between the deburring recess and the flute to remove burrs from an edge of a hole.

Abstract: A drill bit includes a shank, an intermediate portion with a helical flute, and a multi-stepped tip portion extending along the axis. The tip portion includes a cutting tip with a pair of primary cutting edges extending radially outward from the axis, a plurality of steps each having an elongated portion and a tapered portion tapered outward from the elongated portion relative to the axis. The elongated portions progressively increase in diameter from the cutting tip to the intermediate portion. The elongated portion of each step has an axial relief tapered inward toward the axis. A frontmost elongated portion has a first axial relief at a first angle relative to the central axis and a rearmost elongated portion has a second axial relief at a second angle greater than the first angle. The drill bit may be used as a pilot bit together with a holesaw in a system.

Abstract: A robot system for servicing a semiconductor tool includes a cart frame. An arm support frame is fixed to the cart frame and is coupled to a robot arm. An arm frame is connected by hinges to the arm support frame at a first end and to a fixture connect interface at a second end. The fixture connect interface connects to a docking fixture of the semiconductor tool. An arm locking mechanism is attached to the arm support frame for locking the arm frame, when rotated, to an extended position or a folded position. The fixture connect interface connects the cart frame to the semiconductor tool, when the arm frame is locked in the extended position.

Abstract: A system and method for characterizing a memory instance. Characterizing a memory instance includes obtaining a memory instance comprising a plurality of leaf cells. Each of the plurality of leaf cells comprises components. First channel connected components from the components within each of the plurality of leaf cells are determined, and a first super leaf cell is generated by combining a first two or more leaf cells of the plurality of leaf cells based on the first channel connected components. Further, an updated memory instance is generated based on the first super leaf cell, and a timing model is determined for the updated memory instance.

Abstract: Methods and systems are provided for use of a portable speaker system both as part of a vehicular audio system and as a stand-alone audio system. A speaker may be attached to an internal speaker receptacle of a vehicle and coupling to an audio amplifier of the vehicle. Audio performances received by the speaker from the audio amplifier may then be played by the speaker. The speaker may also be decoupling from the audio amplifier of the vehicle and detached from the internal speaker receptacle of the vehicle. Audio performances received by the speaker from a wireless interface coupled to the speaker may then be played by the speaker.

Abstract: A saw blade includes an elongated body extending along a longitudinal axis and having an elongated cutting edge. A first hard metal strip is attached to a first portion of the cutting edge and includes at least one first full hard metal cutting tooth that is set left at a first angle relative to a vertical axis of the body that is generally perpendicular to the longitudinal axis. A second hard metal strip attached to a second portion of the cutting edge and includes a second full hard metal cutting tooth that is set right at a second angle relative the vertical axis.

Abstract: Aspects described herein relate to queuing and processing ticket objects associated with combinations of numbers to enforce a process of elimination for a ticket event. A ticket array for a ticket event may be generated. The ticket array may comprise a plurality of combinations of numbers consisting of combinations of unprocessed numbers and combinations of processed numbers. A ticket object associated with the ticket event may be received from a client computing device. The ticket object may comprise a combination of selected numbers that are added to a ticket queue. There may be a determination of whether the ticket object meets ticket criteria. In response to the ticket object meeting at least one of the ticket criteria, the ticket object may be processed. A notification may be generated after the ticket object has been processed. Furthermore, the notification may be sent to the client computing device.

Abstract: A method for transient analysis of a memory module circuit, the method including: determining port to port resistances between terminals of internal circuits of a plurality of leaf cells of a netlist representing the memory module circuit; generating a plurality of equivalent networks corresponding to the internal circuits of the leaf cells, the equivalent networks being connected to each other; promoting the equivalent networks of the leaf cells to a hierarchical level above the leaf cells in the netlist representing the memory module circuit; shorting one or more terminals of each of the leaf cells to a central node of a corresponding one of the equivalent networks; and performing the transient analysis of the leaf cells of the netlist representing the memory module circuit.

Abstract: Provided herein are methods and compositions for overcoming Low Endotoxin Recovery (LER) and unmasking endotoxins. The compositions and methods provided herein may be used to prepare samples such as drug products for endotoxin testing.

Abstract: A system and method for generating a netlist of a memory device includes receiving a logical netlist file including memory instances and placement information for the memory device. Each memory instance includes leaf cells. Further, a location of a first leaf cell and a location of a second leaf cell of the leaf cells of a first memory instance is determined based on the placement information. A first net segment between the first leaf cell and the second leaf cell is generated based on the location and parasitic elements of the first leaf cell and the location and parasitic elements of the second leaf cell. A parasitic netlist is generated based on the first net segment and the parasitic elements of the first leaf cell and parasitic elements of the second leaf cell.

Abstract: A system and method for characterizing a memory instance. Characterizing a memory instance includes obtaining a memory instance comprising a plurality of leaf cells. Each of the plurality of leaf cells comprises components. First channel connected components from the components within each of the plurality of leaf cells are determined, and a first super leaf cell is generated by combining a first two or more leaf cells of the plurality of leaf cells based on the first channel connected components. Further, an updated memory instance is generated based on the first super leaf cell, and a timing model is determined for the updated memory instance.

Abstract: An accessory tool for a power-driven oscillating tool may include a plate, with a first working section defined along a first peripheral edge portion of the plate, and a second working section defined along a second peripheral edge portion of the plate. The first and second working sections may define cutting or abrading or chipping sections of the accessory tool. The first and second working sections may be separated by a notch formed in a third peripheral edge portion of the plate. Corner portions of the first working section and the second working section may be defined where the first and second working sections meet respective edge portions of the notch, allowing the corner portions to be inserted into and engaged in corresponding corner portions of channels for removal of material from the corner portions of the channels.

Abstract: Among the various aspects of the present disclosure is the provision of methods and compositions for upregulating MHC class II in cancer cells (e.g., a hematological cancer cell). Also provided are methods of treatment for subjects suffering from hematological cancers, comprising administration of interferon-? (IFN-?). The methods of treatment provided herein may be particularly suitable for subjects who have received an allogenic transplant or have suffered a relapse.