Abstract: Provided herein are methods and compositions for the detection of silent carriers of chromosomal deletion alleles in a human subject using haploid cells (e.g., sperm cells or egg cells) derived from the subject. The methods provided herein allow for the detection of silent (2+0) carriers of SMA, where the individual has a deletion of the SMN1 gene on one chromosome 5 homolog and two or more copies of the SMN1 gene on the other chromosome 5 homolog.

Abstract: An alkaline electrochemical cell includes a cathode, an anode which includes an anode active material, and a non-conductive separator disposed between the cathode and the anode, wherein from about 20% to about 50% by weight of the anode active material relative to a total amount of anode active material has a particle size of less than about 75 ?m, and wherein the separator includes a unitary, cylindrical configuration having an open end, a side wall, and integrally formed closed end disposed distally to the open end.

Abstract: A map file includes two-dimensional or three-dimensional geometric data items collectively representing layout of a building. The map file and parsed and the geometric data items analyzed to identify building elements including rooms, floors, and objects of the building, and to identify containment relationships between the elements. A space model having a space graph is constructed. The space graph includes nodes that correspond to the respective building elements and links forming relationships between nodes that correspond to the identified containment relationships. Each node may include node metadata, rules or code that operate on the metadata, and a node type that corresponds to a type of physical space. Some nodes may include user representations or device representations that represent physical sensors associated therewith. The representations may receive data from the respectively represented sensors, and the sensor data becomes available via the space model.

Abstract: An alkaline electrochemical cell includes a cathode, an anode which includes an anode active material, and a non-conductive separator disposed between the cathode and the anode, wherein from about 20% to about 50% by weight of the anode active material relative to a total amount of anode active material has a particle size of less than about 75 ?m, and wherein the separator includes a unitary, cylindrical configuration having an open end, a side wall, and integrally formed closed end disposed distally to the open end.

Abstract: Generating a map based on nodes of a hierarchical graph that defines a topology of a physical space and is configured to provide access to sensor data from devices within the physical space includes accessing the hierarchical graph. The hierarchical graph comprises a plurality of nodes, including a top node for the physical space and a plurality of other nodes coupled to the top node. One of the plurality of nodes comprises an area node that represents an area within the physical space. One of the plurality of nodes also comprises a device node representing a device located within the physical space and a user node. Map data corresponding to a particular node is generated. The generated map data is associated with generating at least a portion of a map corresponding to the particular node. The generated map data corresponding to the particular node is stored within the hierarchical graph.

Abstract: Articles and semiconductor packages that incorporate glass-based substrates are disclosed, as well as methods of forming thereof. An article includes a glass-based substrate comprising first and second major surfaces spaced a distance from and parallel to each other, and a tapered via extending through the substrate. The tapered via includes a cross section that is symmetrical about a plane that is between and equidistant to the first and second major surfaces of the glass-based substrate and an interior wall with a first tapered region and a second tapered region positioned between the first major surface and the plane. The respective slopes of the first and second tapered regions are constant and the slope of the first tapered region is not equal to the slope of the second tapered region.

Abstract: Described herein are systems and methods for a media application including an interactive grid display. A method may comprise displaying a grid including a central hub and a plurality of spokes connected to the central hub, inserting a first media element on a first spoke of the grid, the first media element including a first timestamp and activating a first media file, inserting a second media element on the first spoke of the grid, the second media element including a second timestamp and activating a second media file, wherein the second media file is related to the first media file, comparing the first timestamp to the second timestamp, and arranging the presentation of the first and second media elements along the first spoke based on the compared first and second timestamps.

Abstract: Articles and semiconductor packages that incorporate glass-based substrates are disclosed, as well as methods of forming thereof. An article includes a glass-based substrate comprising first and second major surfaces spaced a distance from and parallel to each other, and a tapered via extending through the substrate. The tapered via includes a cross section that is symmetrical about a plane that is between and equidistant to the first and second major surfaces of the glass-based substrate and an interior wall with a first tapered region and a second tapered region positioned between the first major surface and the plane. The respective slopes of the first and second tapered regions are constant and the slope of the first tapered region is not equal to the slope of the second tapered region.

Abstract: Pairing data associated with a second device may be received at a first device. The pairing data may be received from a server. A first authentication proof may be generated based on the pairing data received from the server. A second authentication proof may be received from the second device. Furthermore, an authentication status of the second device may be updated based on a comparison of the first authentication proof that is based on the pairing data received from the server and the second authentication proof that is received from the second device.

Abstract: Controlling environmental conditions. A method includes using one or more sensors in a location, identifying an entity in the location. The method further includes identifying one or more roles for the entity. The method further includes based on the one or more roles for the entity, modifying environmental conditions in the location, by modifying one or more devices associated with the location.

Abstract: A method and system for recognizing (and/or predicting) failures of sensors used in monitoring gas turbines applies a sparse coding process to collected sensor readings and defines the L-1 norm residuals from the sparse coding process as indicative of a potential sensor problem. Further evaluation of the group of residual sensor readings is perform to categorize the group and determine if there are significant outliers (“abnormal data”), which would be considered as more likely associated with a faulty sensor than noisy data. A time component is introduced into the evaluation that compares a current abnormal result with a set of prior results and making the faulty sensor determination if a significant number of prior readings also have an abnormal value. By taking the time component into consideration, the number of false positives is reduced.

Abstract: A computing system includes a physical space monitoring interface configured to receive status parameters from a plurality of physical space monitors, each of the physical space monitors configured to report a status parameter for one more locations, devices, or people associated with a physical space. An efficiency analysis machine analyzes the status parameters to determine at least one usage efficiency metric for the physical space and at least one physical space efficiency insight. An analytics interface graphically displays the usage efficiency metric and the physical space efficiency insight, the physical space efficiency insight including a recommendation to change a physical space usage policy affecting one or more locations, devices, or people associated with the physical space to improve the usage efficiency metric.

Abstract: Dynamically scheduling spaces for one or more users may include accessing one or more sensors and/or services configured to monitor a plurality of physical spaces to obtain sensor data corresponding to each of the physical spaces of the plurality of physical spaces. User data associated with one or more users may also be accessed. Accessing the user data associated with the one or more users may include identifying one or more characteristics of the one or more users and/or a context of a meeting. Based on the sensor data and the user data, a physical space of the plurality of physical spaces may be correlated to the one or more users. A notification may also be sent to at least one of the one or more users that identifies the correlation between the physical space and the one or more users.

Abstract: Generating a map based on nodes of a hierarchical graph that defines a topology of a physical space and is configured to provide access to sensor data from devices within the physical space includes accessing the hierarchical graph. The hierarchical graph comprises a plurality of nodes, including a top node for the physical space and a plurality of other nodes coupled to the top node. One of the plurality of nodes comprises an area node that represents an area within the physical space. One of the plurality of nodes also comprises a device node representing a device located within the physical space and a user node. Map data corresponding to a particular node is generated. The generated map data is associated with generating at least a portion of a map corresponding to the particular node. The generated map data corresponding to the particular node is stored within the hierarchical graph.

Abstract: A meeting insight computing system includes a meeting evaluation machine configured to collect quality parameters from meeting quality monitoring devices. The quality parameters each quantify meeting conditions during one or more previously-elapsed meetings and are usable to determine an overall quality score for each of the one or more previously-elapsed meetings. A graphical scheduling interface is configured to facilitate scheduling of an upcoming meeting at a designated meeting time, in a meeting location, and with one or more meeting participants. An insight generation machine is configured to report a meeting insight via the graphical scheduling interface. The meeting insight is based on the meeting time, the meeting location, the one or more meeting participants, and the quality parameters, and includes a recommendation to change one or more of the meeting time, meeting location, and meeting participants to improve a quality score of the upcoming meeting.

Abstract: Generating a map based on nodes of a hierarchical graph that defines a topology of a physical space and is configured to provide access to sensor data from devices within the physical space includes accessing the hierarchical graph. The hierarchical graph comprises a plurality of nodes, including a top node for the physical space and a plurality of other nodes coupled to the top node. One of the plurality of nodes comprises an area node that represents an area within the physical space. One of the plurality of nodes also comprises a device node representing a device located within the physical space and a user node. Map data corresponding to a particular node is generated. The generated map data is associated with generating at least a portion of a map corresponding to the particular node. The generated map data corresponding to the particular node is stored within the hierarchical graph.

Abstract: A glass sensor substrate including metallizable through vias and related process is provided. The glass substrate has a first major surface, a second major surface and an average thickness of greater than 0.3 mm. A plurality of etch paths are created through the glass substrate by directing a laser at the substrate in a predetermined pattern. A plurality of through vias through the glass substrate are etched along the etch paths using a hydroxide based etching material. The hydroxide based etching material highly preferentially etches the substrate along the etch path. Each of the plurality of through vias is long compared to their diameter for example such that a ratio of the thickness of the glass substrate to a maximum diameter of each of the through vias is greater than 8 to 1.

Abstract: Provided herein are methods and compositions for the detection of silent carriers of chromosomal deletion alleles in a human subject using haploid cells (e.g., sperm cells or egg cells) derived from the subject. The methods provided herein allow for the detection of silent (2+0) carriers of SMA, where the individual has a deletion of the SMN1 gene on one chromosome 5 homolog and two or more copies of the SMN1 gene on the other chromosome 5 homolog.

Abstract: An alkaline electrochemical cell includes a cathode, an anode which includes an anode active material, and a non-conductive separator disposed between the cathode and the anode, wherein from about 20% to about 50% by weight of the anode active material relative to a total amount of anode active material has a particle size of less than about 75 ?m, and wherein the separator includes a unitary, cylindrical configuration having an open end, a side wall, and integrally formed closed end disposed distally to the open end.

Abstract: A plant transportation apparatus enables the shipment of multiple plants such as flowers in a single container. The plants are held in place by a cap. It is contemplated that the apparatus could move small or large quantities of plants.