Abstract: A patient interface including a plenum chamber, a first seal-forming structure for forming a seal around the patient's mouth, and a second seal-forming structure for forming a seal around the patient's nares. The patient interface further includes at least one stopper rib disposed in the cavity of the plenum chamber spaced apart from the first seal-forming structure in a rest position. The first seal-forming structure configured to contact the at least one stopper rib in an operational position. The at least one stopper rib configured to oppose compression of the first seal-forming structure in an anterior direction. The second seal-forming structure is not configured to contact the at least one stopper rib.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: A golf club head and golf club having large head dimensions, and large face characteristics, as well as unique mass property attributes driven by relationships not often considered in conventional club head design, to achieve a resistance to squaring the club head during a golf swing that is comfortable to the novice golfer, while increasing stability during off-center impacts and obtaining preferred launch characteristics. This is achieved in part via establishing a club head configuration and associated weight distribution to yield a center of gravity location that results in a preferred magnitude of Delta1 and Delta2 values, CG angle, moments of inertia, and associated ratios, relationships, and club head mass property characteristics influenced by these variables to achieve improved performance.

Abstract: An apparatus for providing normalized hydrogen correction factor comprises: a set of sensors configured to measure telemetry data of a hydrogen production plant; a memory; a database; and a processor operatively coupled to the memory, the database, and the set of sensors. The processor is configured to: receive the telemetry data from the set of sensors; receive supplier data from the database; receive customer data from a customer; determine, using a machine learning model stored in the memory, and based on the telemetry data, the supplier data, and the customer data, a normalized hydrogen correction factor; and provide the normalized hydrogen correction factor to the customer.

Abstract: A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

Abstract: A device includes a logic circuit comprising a clockless single flux quantum logic gate which comprises a plurality of input ports, an output port, an output Josephson junction, and a plurality of dynamic storage loop circuits and isolation buffer circuits. The output Josephson junction is coupled to an output of each dynamic storage loop circuit and configured to drive the output port. Each isolation buffer circuit is coupled to a respective input port, and a respective dynamic storage loop circuit and configured to absorb a circulating current of an antifluxon which is injected into the respective dynamic storage loop circuit to prevent the antifluxon from being output from the respective input port, and to inject a fluxon into the respective dynamic storage loop circuit in response to a single flux quantum pulse applied to the respective input port, and annihilate an antifluxon present in the respective dynamic storage loop circuit.

Abstract: A virtual network provider system supports a virtual network including virtual machines that are each assigned to an underlay address of an underlay addressing scheme. The virtual network provider system further includes multiple routing domains each defined to include a different subset of the virtual machines. Each of the routing domains is assigned to a range of overlay addresses of an overlay addressing scheme. For each routing domain, the assigned range of overlay addresses is allocated among the subset of the virtual machines in the routing domain. The system further includes a virtual network host configured to use addresses of the overlay addressing scheme to selectively route messages between endpoints on select pairs of the virtual machines assigned to a same routing domain of the plurality of routing domains.

Abstract: Disclosed are examples of systems, apparatus, methods and computer program products for sharing and publishing files. In one aspect, the database system can maintain a user database, a file database and a library. The database system can receive a first request initiated by a first user to share a first file with one or more second users and, responsive to the first request, enable a second set of one or more permissions for each of the second users. The database system also can receive a second request initiated by the first user to publish the first file to the library and, responsive to the second request, publish the first file to the library. The database system additionally can restrict access to the published file based on permissions associated with the library.

Abstract: A patient interface for delivering breathable gas to a patient includes a sealing portion including a nose tip engagement portion adapted to form a seal with the patient's nose tip, an upper lip engagement portion adapted to form a seal with the patient's upper lip and/or base of the patient's nares, and nostril engagement flaps adapted to form a seal with the patient's nares. The nose tip engagement portion, the upper lip engagement portion, and the nostril engagement flaps are all structured to extend or curve outwardly from a supporting wall defining an air path.

Abstract: The present invention relates generally to a method and system (10) for classifying vehicle behaviour, particularly abnormal behaviour of civil aircraft (12). The method may comprise receiving aircraft data from an aircraft (12) which is to be classified; and determining whether the received aircraft data comprises identification information for the aircraft (12). In response to a determination that the received aircraft data comprises identification information, the method may comprise using said identification information to classify the behaviour of the aircraft (12). In response to a determination that the received aircraft data does not comprises identification information, the method may comprise obtaining the position of the aircraft and comparing the obtained position to an expected route for the aircraft to classify the behaviour of the aircraft (12).

Abstract: A dose counting system of an injection device or of a module configured to be used with or applied to an injection device is described. The dose counting system includes a sensor arrangement including a first sensor configured to output a first signal and a second sensor configured to output a second signal; and a processor configured to: detect a peak in the first signal when the first signal has increased by at least a predefined up threshold and the first signal exceeds the value of the second signal by more than a predetermined crossover threshold; determine that a unit of medicament has been administered when the first signal drops from the peak by more than a predefined down threshold and the preceding peak occurred in the second signal; and determine a medicament dosage administered by the injection device by counting the administered units of medicament.

Abstract: Two Silicon Carbide negative positive negative transistors realized on a monolithic substrate as a differential pair to keep their base-emitter junctions at nearly the same temperature such that their kT/q sensitivities tract together with their base connections electrically connected to the cold junction terminals of a thermocouple to create an amplified differential voltage across output load resistors while operating at high temperature.

Abstract: Various aspects and embodiments are directed to a streamlined computer device and a graphical user interface that organizes interface elements into views of computer content for presentation to a user. Various views of digital media content permits users to easily and efficiently access various digital media content. Different views are used to provide an interface that is responsive to configurations of the device and responsive to activity being performed by the user. Aspects include permitting the user to maintain and manage digital media content libraries. According to some embodiments, the libraries comprise user digital media content and references digital media content. Functionality provided to a user can be tailored to the type of content displayed, accessed and/or managed. According to various aspects, methods and systems are provided for accessing and managing digital media libraries on a streamlined computing device with a plurality selectable I/O profiles.

Abstract: Disclosed are compounds having structural formulas (I)-(XI), and related pharmaceutical compositions. Also disclosed are methods of selecting and treating human subjects suffering from a kidney disease, using the compounds of formulas (I)-(XI), and methods of determining the efficacy of TRPC5 inhibitor therapies using the same.

Abstract: Vehicle capture assemblies and related devices, systems, and methods include one or more probe assemblies for engaging with and securing the target vehicle. The one or more probe assemblies may include one or more attenuation features or movable joints to enable and/or dampen movement of the one or more probe assemblies relative to a capture vehicle.

Abstract: A button for a drug delivery device with a reduced operating loudness includes a plate-like button body forming a touch surface, wherein the plate-like button body is coupled by an axial supporting member to a noise-generating interface of the drug delivery device and movable into a longitudinal direction of the drug delivery device, wherein the plate-like button body includes a material composite with at least one first component consisting of a first material and at least one second component consisting of a second material different from the first material, wherein the at least one first component and the at least one second component are coupled via at least one coupling plane that is at least sectionwise slanted or perpendicular to the longitudinal direction. Further, the disclosure describes a button assembly for a drug delivery device which is shock resistant.

Abstract: An augmented wellness environment is generated at a media processing device, where the augmented wellness environment includes a virtual object. The content of the augmented wellness environment is determined by the activities (e.g., participation in wellness activities) of the user and one or more additional users (e.g., users at a similar location to the user). The augmented wellness environment may be modified based on interactions between users, and the augmented wellness environment may also be modified based on user activity data, such as biometric data (e.g., heart rate, breathing rate, etc.) of one or more users experiencing the augmented wellness environment. Using the user activity data, the system may determine a user's present mental state. The system can modify the augmented wellness environment to alter the user's present mental state to a target mental state.

Abstract: Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac.

Abstract: The invention concerns a process for the electrochemical production of formate. The process is performed in an electrochemical cell comprising a cathode compartment containing a cathode, an anode compartment containing a nickel-based anode and an ion exchange membrane separating the anode compartment from the cathode compartment. The process comprises the following steps: (a) feeding an anolyte comprising at least one polyol to the anode compartment; (b) feeding a catholyte comprising CO2 to the cathode compartment; (c) and applying a voltage difference between the cathode and the anode such that at the cathode CO2 is reduced to formate and at the anode the at least one polyol is oxidized to formate.

Abstract: A novel roof-top autonomous vehicle control system for converting a non-autonomous vehicle into an autonomous vehicle includes a weatherproof housing that removably attaches to the roof of a host vehicle. The housing supports modular attachment of various sensors, receivers, computers, and other electrical components that can be installed, removed, and/or interchanged without disrupting the initial calibration thereof. In a particular embodiment, various internal electrical components of the system are mounted on a tray which can be mounted in, and removed from, the housing without disrupting the initial calibration of the various sensors. In a more particular embodiment, the housing includes a plurality of removable panels and windows that provide access to the inside of the housing.