Abstract: Reconciling Adaptive Bitrate (ABR) segments across redundant sites may be provided. First, a working manifest may be set to match a primary downstream manifest and the working manifest may be updated using an auxiliary downstream manifest. Next, first segments missing from the working manifest as identified during updating the working manifest using the auxiliary downstream manifest may be copied from the auxiliary downstream manifest to the primary downstream manifest. The working manifest may then be updated using a primary upstream manifest. And then second segments missing from the working manifest as identified during updating the working manifest using the primary upstream manifest may be copied from the primary upstream manifest to the primary downstream manifest.

Abstract: An application analysis platform enables automatic generation of abstract program representations (APRs) that are amenable to static analyses for finding security vulnerabilities. The APR is generated automatically, preferably from an existing build system or a source repository, and then encapsulated into a binary archival format for consumption by a static analysis tool, which operates on-premises or in the cloud. The abstract program representation is a highly compact version of the actual source code it represents. The archival format obfuscates the source code that is subjected to the analysis, thus protecting it from being reverse-engineered when moved off-premises or otherwise shared with other users, teams and even organizations.

Abstract: A system for treating a linear wound on a patient has a closing dressing bolster for placing on the patient's epidermis over the linear wound, a sealing subsystem for providing a seal over the closing dressing bolster and the patient, and a reduced-pressure subsystem for delivering reduced pressure to the sealing subsystem. The sealing subsystem and reduced pressure subsystem are operable to deliver reduced pressure to the closing dressing bolster. The closing dressing bolster is operable under reduced pressure to develop a inward closing. The closing dressing bolster may include one or more closing members on each side of a center wound area to create the inward closing when under reduced pressure. A compressive force may also be developed. Other systems and methods are presented.

Abstract: A transmission electron microscope is provided for imaging a sample. The microscope has a stage to hold a sample and an electron beam column to direct an electron beam onto a field of view on the sample. The electron beam column includes an electron beam source to generate an electron beam, and electron beam optics to converge the electron beam onto a field of view on the sample. The microscope also has a beam scanner to scan the electron beam across multiple fields of view on the sample. The microscope additionally has a detector to detect radiation emanating from the sample to generate an image. A controller is provided to analyze the detected radiation to generate an image of the sample.

Abstract: Content delivery network storage may be provided. A first proxy module may receive a first content object request from a first user device. The first content object request may correspond to a content object. Next, the first proxy module may send the first content object request to a first cache module. The first cache module may then obtain the content object corresponding to the first content object request from an object store. The object store may be shared by a plurality of cache modules including the first cache module. The first proxy module may then receive, from the first cache module, the obtained content object. The first proxy module may send the content object to the first user device.

Abstract: A system for providing reduced-pressure treatment to a moveable tissue site, such as a joint, includes a flexible dressing bolster. The flexible dressing bolster has a first side and a second, inward-facing side, and a plurality of flexion joints formed on the flexible dressing bolster. The system further includes a sealing subsystem for providing a fluid seal over the flexible dressing bolster and the patient's epidermis and a reduced-pressure subsystem for delivering a reduced pressure to the sealing subsystem. The sealing subsystem and reduced-pressure subsystem are operable to deliver a reduced pressure to the moveable tissue site. The flexible dressing bolster is operable to allow articulation or movement of the moveable tissue site. The sealing subsystem may include a drape with folds. Other systems, apparatuses, and methods are presented.

Abstract: The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R9, X, m and n are as defined herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating kappa opioid (?-opioid) associated disorders including, e.g., a neurological disorder, or psychiatric disorder such as a neurocognitive disorder, substance abuse disorder, depressive disorder, anxiety disorder, trauma and stressor related disorder and feeding and eating disorder.

Abstract: A system for providing reduced-pressure treatment to a moveable tissue site, such as a joint, includes a flexible dressing bolster. The flexible dressing bolster has a first side and a second, inward-facing side, and a plurality of flexion joints formed on the flexible dressing bolster. The system further includes a sealing subsystem for providing a fluid seal over the flexible dressing bolster and the patient's epidermis and a reduced-pressure subsystem for delivering a reduced pressure to the sealing subsystem. The sealing subsystem and reduced-pressure subsystem are operable to deliver a reduced pressure to the moveable tissue site. The flexible dressing bolster is operable to allow articulation or movement of the moveable tissue site. The sealing subsystem may include a drape with folds. Other systems, apparatuses, and methods are presented.

Abstract: Disclosed herein are systems and methods for monitoring calibration of positron emission tomography (PET) systems. In some variations, the systems include an imaging assembly having a gantry comprising a plurality of positron emission detectors. A housing may be coupled to the gantry, and the housing may include a bore and a radiation source holder spaced away from a patient scan region within the bore. A processor may be configured to receive positron emission data from the positron emission detectors and to distinguish the positron emission data from the radiation source holder and from the patient scan region. A fault signal may be generated when the positron emission data from the radiation source holder exceeds one or more threshold parameters or criteria.

Abstract: Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac.

Abstract: A see-through dressing assembly is presented for use with a reduced-pressure system for treating a wound on a patient using reduced pressure that allows visual observation of the wound during treatment. The dressing assembly includes a bolster for providing a directed force when under reduced pressure, a sealing member for covering the bolster and providing a seal over the bolster and a patient's epidermis, and wherein the bolster and sealing member are formed from see-through materials sufficient to allow perception of color from a point external to the system. Other systems, dressings, and methods are presented.

Abstract: A charged-particle beam microscope includes a charged-particle beam source to generate a charged-particle beam. A stage is provided to hold a sample in the path of the charged-particle beam. Beam optics are provided to illuminate the sample with the charged-particle beam. One or more detectors are provided to detect radiation emanating from the sample as a result of the illumination. A controller may control one or more of the beam optics, stage, and detectors to generate an image of the sample based on the detected radiation.

Abstract: The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R9, X, m and n are as defined herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating kappa opioid (?-opioid) associated disorders including, e.g., a neurological disorder, or psychiatric disorder such as a neurocognitive disorder, substance abuse disorder, depressive disorder, anxiety disorder, trauma and stressor related disorder and feeding and eating disorder.

Abstract: Content delivery network storage may be provided. A first proxy module may receive a first content object request from a first user device. The first content object request may correspond to a content object. Next, the first proxy module may send the first content object request to a first cache module. The first cache module may then obtain the content object corresponding to the first content object request from an object store. The object store may be shared by a plurality of cache modules including the first cache module. The first proxy module may then receive, from the first cache module, the obtained content object. The first proxy module may send the content object to the first user device.

Abstract: A method is provided in one example embodiment and includes generating a key associated with a virtual asset associated with content to be provided to a client device, where the key indicates at least one parameter for accessing the content; generating the virtual asset; receiving a request for the content; identifying a format being requested for the content; using the virtual asset to identify common format content to be retrieved and to identify the key; using the key to retrieve the common format content; and transforming the common format content such that it can be delivered to the client device in the format that was requested.

Abstract: A method captures diagnostic trace information in a computer system having a plurality of software images. Information is received that is associated with a first failure in a first one of the plurality of software images. The received information is distributed to others of the plurality of software images. Further information is captured that is associated with a second failure in another one of the plurality of software images. The information associated with a first failure in a first one of said plurality of software images is combined with the information associated with a second failure in another of said plurality of software images, and the combined information is analyzed in order to determine a cause of the first failure.

Abstract: A charged-particle beam microscope is provided for imaging a sample. The microscope has a vacuum chamber to maintain a low-pressure environment. A stage is provided to hold a sample in the vacuum chamber. The microscope has a compact evaporator in the vacuum chamber to evaporate and deposit a coating onto a surface of the sample. The microscope also has a charged-particle beam column is provided to direct a charged-particle beam onto the coating on the surface of the sample. The charged-particle beam column includes a charged-particle beam source to generate a charged-particle beam and charged-particle beam optics to converge the charged-particle beam onto the sample. A detector is provided to detect charged-particle radiation emanating from the coating on the surface of the sample to generate an image. A controller analyzes the detected charged-particle radiation to generate an image of the sample.

Abstract: An application analysis platform enables automatic generation of abstract program representations (APRs) that are amenable to static analyses for finding security vulnerabilities. The APR is generated automatically, preferably from an existing build system or a source repository, and then encapsulated into a binary archival format for consumption by a static analysis tool, which operates on-premises or in the cloud. The abstract program representation is a highly compact version of the actual source code it represents. The archival format obfuscates the source code that is subjected to the analysis, thus protecting it from being reverse-engineered when moved off-premises or otherwise shared with other users, teams and even organizations.

Abstract: A system for treating a linear wound on a patient has a closing dressing bolster for placing on the patient's epidermis over the linear wound, a sealing subsystem for providing a seal over the closing dressing bolster and the patient, and a reduced-pressure subsystem for delivering reduced pressure to the sealing subsystem. The sealing subsystem and reduced pressure subsystem are operable to deliver reduced pressure to the closing dressing bolster. The closing dressing bolster is operable under reduced pressure to develop a inward closing. The closing dressing bolster may include one or more closing members on each side of a center wound area to create the inward closing when under reduced pressure. A compressive force may also be developed. Other systems and methods are presented.

Abstract: A computer system and computer program captures diagnostic trace information in a computer system having a plurality of software images. Information is received that is associated with a first failure in a first one of the plurality of software images. The received information is distributed to others of the plurality of software images. Further information is captured that is associated with a second failure in another one of the plurality of software images. The information associated with a first failure in a first one of said plurality of software images is combined with the information associated with a second failure in another of said plurality of software images, and the combined information is analyzed in order to determine a cause of the first failure.