Abstract: Methods and apparatus for controlling a mobile robot to perform an action are provided. The method includes receiving, by at least one computing device associated with a mobile robot, first sensor data and second sensor data, providing as input to at least one machine learning model, the first sensor data, the second sensor data, and camera intrinsics associated with at least one camera configured to sense the first sensor data and/or the second sensor data, wherein the at least one machine learning model is trained to output polyhedron information representing a set of objects in an environment of the mobile robot, and controlling the mobile robot to perform an action based, at least in part, on the polyhedron information output from the at least one machine learning model.

Abstract: A system that generates an explicit plan to separately guide multiple mechanisms to collectively generate a response to an event. The multiple mechanisms can include a program generation mechanism and a response generation mechanism, each of which may be provided with the generated plan. Each mechanism can utilize a prediction engine, such as for example a machine learning model or large language model, to perform a task based on the generated plan. The event can include an event triggered based on an interaction between an automated agent and a customer. The plan may be generated using a state machine, a machine learning model, such as for example a large language model, or some other mechanism. The plan can be structured such that it can be interpreted and audited for conformance with predefined constraints.

Abstract: A system generates a response to a change of state by an automated agent using structure-based constraints. The system receives input regarding an interaction with a client, external data, and current operations data. The received input is used to generate a content sketch. The content sketch can include a plan for how to generate the response. The program language can be constrained to a set of known atoms, such as for example particular specified function, values, and flow control. Relevant instructions for generating a response are generated from the content sketch and an instruction bank. The relevant instructions are then used to generate a response. The generated response may then be executed by the automated agent system.

Abstract: The disclosure provides a system and method that rejects, or at least reduces, the effect of low frequency voltage that is fed forward to the output of an NPC converter, such as an ANPC converter. For example, a controller is disclosed that is configured to modify PWM signals to adapt to different magnitudes and frequencies of an input DC voltage ripple in real time. Additionally, the disclosure provides improved reliability of converters by including one or more redundant phases and a modified phase module. In one example, an NPC converter is disclosed that includes: (1) three different phase modules, (2) at least one redundant phase module, and (3) switching circuitry configured to enable one of the at least one redundant phase modules in response to failure of one of the three different phase modules.

Abstract: The invention relates to proteins that contain the CD4 domain 1 and the CD4 domain 2 (CD4 D1D2), wherein the CD4 D1D2 contains one or more mutations compared to wild-type human CD4 D1D2, and to methods of using the proteins for treating a human immunodeficiency virus (HIV) infection in a subject.

Abstract: Aspects and embodiments relate to apparatus and methods to identify whether a drug is present in a provided sample.

Abstract: The invention relates to proteins that contain the CD4 domain 1 and the CD4 domain 2 (CD4 D1D2), wherein the CD4 D1D2 contains one or more mutations compared to wild-type human CD4 D1D2, and to methods of using the proteins for treating a human immunodeficiency virus (HIV) infection in a subject.

Abstract: The present invention provides methods and compositions for optimally co-expressing in a primate subject a tyrosylprotein sulfotransferase (TPST) and a lentiviral gp120-binding molecule to provide potent and long term protection against lentiviral infections.

Abstract: Provided herein are delivery particle systems (XDP) useful for the delivery of payloads of any type. In some embodiments, a XDP particle system with tropism for target cells of interest is used to deliver CRISPR/Cas polypeptides (e.g., CasX proteins) and guide nucleic acids (gNA), for the modification of nucleic acids in target cells. Also provided are methods of making and using such XDP to modify the nucleic acids in such cells.

Abstract: A software development system and method which reduces development cycle times, improves software quality, and indicates speed to market for software is provided. The system integrates development resources to streamline the process of utilizing those resources by a developer or other personnel. A software development workbench and associated toolchain may be used to further improve the software development process.

Abstract: Provided herein are delivery particle systems (XDP) useful for the delivery of payloads of any type. In some embodiments, a XDP particle system with tropism for target cells of interest is used to deliver CRISPR/Cas polypeptides (e.g., CasX proteins) and guide nucleic acids (gNA), for the modification of nucleic acids in target cells. Also provided are methods of making and using such XDP to modify the nucleic acids in such cells.

Abstract: The invention relates to proteins that contain the CD4 domain 1 and the CD4 domain 2 (CD4 D1D2), wherein the CD4 D1D2 contains one or more mutations compared to wild-type human CD4 D1D2, and to methods of using the proteins for treating a human immunodeficiency virus (HIV) infection in a subject.

Abstract: A software development system and method which reduces development cycle times, improves software quality, and indicates speed to market for software is provided. The system integrates development resources to streamline the process of utilizing those resources by a developer or other personnel. A software development workbench and associated toolchain may be used to further improve the software development process.

Abstract: A system and method for managing a software development project is provided. The system integrates software development workbench and associated toolchain to link a plurality of software development tools according to a dependency that illustrates a relationship between the plurality of software development tools to indicate to a developer that the one or more software development tools necessary to build, test, deploy, and/or run the software development project, and to indicate the operational status of the a plurality of software development tools to streamline the process of utilizing those tools by a developer or other personnel.

Abstract: Methods and systems for managing access to a data location associated with a vehicle. The method includes detecting, by one or more sensors of the vehicle, vehicle data. The method also includes recording, by an electronic control unit (ECU) of the vehicle, the vehicle data to the data location. The method also includes storing, by a smart contract located on a blockchain, an access state associated with the data location, the access state indicating one or more devices having access to the data location. The method also includes communicating, by the ECU, an instruction to the smart contract to change the access state associated with the data location to grant access to a third-party device or revoke access from the third-party device.

Abstract: The present invention provides methods and compositions for optimally co-expressing in a primate subject a tyrosylprotein sulfotransferase (TPST) and a lentiviral gp120-binding molecule to provide potent and long term protection against lentiviral infections.

Abstract: The present invention provides methods and compositions for optimally co-expressing in a primate subject a tyrosylprotein sulfotransferase (TPST) and a lentiviral gp120-binding molecule to provide potent and long term protection against lentiviral infections.

Abstract: A software development system and method which reduces development cycle times, improves software quality, and indicates speed to market for software is provided. The system integrates development resources to streamline the process of utilizing those resources by a developer or other personnel. A software development workbench and associated toolchain may be used to further improve the software development process.

Abstract: A cycloidal differential includes a driven body and a coupling ring supported for rotation within the driven body. The coupling ring defines a first eccentric race and a second eccentric race on opposing sides of the coupling ring. The cycloidal differential further includes first and second cycloidal drives. The first cycloidal drive includes a first roller disk received in the first eccentric race and a first output member operably coupled to the first roller disk and configured to couple with a half shaft. The second cycloidal drive includes a second roller disk received in the second eccentric race and a second output member operably coupled to the second roller disk and configured to couple with another half shaft.

Abstract: A cycloidal differential includes a driven body and a coupling ring supported for rotation within the driven body. The coupling ring defines a first eccentric race and a second eccentric race on opposing sides of the coupling ring. The cycloidal differential further includes first and second cycloidal drives. The first cycloidal drive includes a first roller disk received in the first eccentric race and a first output member operably coupled to the first roller disk and configured to couple with a half shaft. The second cycloidal drive includes a second roller disk received in the second eccentric race and a second output member operably coupled to the second roller disk and configured to couple with another half shaft.