Abstract: The present invention provides a single surgical method, procedure and/or system that creates open direct visual and/or physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure may be performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: Systems and methods for determining playback times for content items presented in playlists are disclosed. Techniques described herein include identifying a first content item in a content reel comprising a plurality of content items, and determining that the first content item has an undefined display duration. In response to the first content item having an undefined display duration, a display duration for which the first content item should be displayed when presented in the content reel is calculated. The content reel can be provided for display at a client device, such that the first content item is displayed for the display duration.

Abstract: A therapeutic agent delivery catheter system includes an elongate tube defining a lumen therein formed from biocompatible material and sized to insert in a patient. The elongate tube has a length that extends to reach a treatment region of the patient. A pattern of slits forming microvalves penetrates an outer wall of the tube. The slits are small enough to remain closed to contain a solution of therapeutic agent, and are configured to open in response to a pressure pulse in the lumen and emit a microjet of therapeutic agent from each slit in the pattern of slits distributed along the rostro caudal extent of the implanted catheter.

Abstract: Described herein are scintillation detectors such as alpha- and beta-particle scintillation detectors along with methods of preparing and using such detectors. The scintillation detector comprises a protective layer including light-blocking nanoparticles.

Abstract: A method for evaluating a target, the target having a surface, includes pulsing a defined, energetic particle beam through the surface and into the target such that particle energy deposition from the particle beam is concentrated in a subsurface target volume within a target medium of the target. The deposited particle energy induces a thermoelastic expansion of the target medium in the target volume that generates a corresponding acoustic wave. The method further includes detecting the acoustic wave from the target medium.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open direct visual and/or physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure may be performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open direct visual and/or physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure may be performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: A sonar system is provided including a display screen, a transducer assembly including at least one transducer that is configured to emit one or more sonar signals into an underwater environment and receive sonar return data reflected from one or more objects, and a sonar module configured to generate a 3D matrix based on the sonar return data including a plurality of sonar returns that are each defined by a 3D positional value, determine a group of the plurality of sonar returns associated with an object, assign a predetermined icon to the determined group, and generate and display 3D image of the sonar return data. The predetermined icon is positioned within the 3D image at a position that corresponds to the position of the determined group such that the position of the predetermined icon corresponds to the position of the object.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that initially comprises spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a lead template for optimal lead placement and spacing during a surgical method and procedure for implantation of a neuromodulation system at a spinal treatment site.

Abstract: Described herein are scintillation detectors such as alpha- and beta-particle scintillation detectors along with methods of preparing and using such detectors. The scintillation detector comprises a protective layer including light-blocking nanoparticles.

Abstract: A method for evaluating a target, the target having a surface, includes pulsing a defined, energetic particle beam through the surface and into the target such that particle energy deposition from the particle beam is concentrated in a subsurface target volume within a target medium of the target. The deposited particle energy induces a thermoelastic expansion of the target medium in the target volume that generates a corresponding acoustic wave. The method further includes detecting the acoustic wave from the target medium.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that initially comprises spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: A patch for treating vascular ulcers caused by excessive enzymatic activity may include a substrate configured to span a vascular ulcer as well as a linking material that is disposed relative to the substrate and has an affinity for an enzyme involved in causing the vascular ulcer. A magnetic material may be coupled to the linking material. In some cases, the enzymes involved in causing the vascular ulcer may become coupled to the linking material and thus become coupled to the magnetic material so that that the enzymes can be removed by applying a magnetic field in the proximity of the vascular ulcer. The enzymes may include matrix metalloproteinases.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open direct visual and/or physical access to an identified spinal treatment site that initially comprises spinal levels to be treated, wherein the spinal levels include at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the low-profile pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.