Abstract: A patch for treating vascular ulcers caused by excessive enzymatic activity may include a substrate configured to span a vascular ulcer as well as a linking material that is disposed relative to the substrate and has an affinity for an enzyme involved in causing the vascular ulcer. A magnetic material may be coupled to the linking material. In some cases, the enzymes involved in causing the vascular ulcer may become coupled to the linking material and thus become coupled to the magnetic material so that that the enzymes can be removed by applying a magnetic field in the proximity of the vascular ulcer. The enzymes may include matrix metalloproteinases.

Abstract: The present invention provides various embodiments of neuromodulation systems, and improvements thereof, capable of being implanted at a spinal treatment site and capable of being implanted at the same time and/or in combination with a spinal procedure being performed at the spinal treatment site. The present invention further includes improvements in the number and types of neuromodulation therapies that can be implanted at the spinal treatment site and improvements to the neuromodulation systems used for delivering such neuromodulation therapies.

Abstract: The present invention comprises implantable neuromodulation systems and methods comprising a protective pouch that at least partially encases an implantable pulse generator prior to implanting in a patient and is adapted to be secured within the surgical site. The pouch may be secured to a pedicle screw and/or a fixation rod, or to a vertebral body.

Abstract: The present invention provides various embodiments of neuromodulation systems, and improvements thereof, capable of being implanted at a spinal treatment site and capable of being implanted at the same time and/or in combination with a spinal procedure being performed at the spinal treatment site. The present invention further includes improvements in the number and types of neuromodulation therapies that can be implanted at the spinal treatment site and improvements to the neuromodulation systems used for delivering such neuromodulation therapies.

Abstract: The present invention provides various embodiments of neuromodulation systems, and improvements thereof, capable of being implanted at a spinal treatment site and capable of being implanted at the same time and/or in combination with a spinal procedure being performed at the spinal treatment site. The present invention further includes improvements in the number and types of neuromodulation therapies that can be implanted at the spinal treatment site and improvements to the neuromodulation systems used for delivering such neuromodulation therapies.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open direct visual and/or physical access to an identified spinal treatment site that initially comprises spinal levels to be treated, wherein the spinal levels include at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the low-profile pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open direct visual and/or physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure may be performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that initially comprises spinal levels to be treated, wherein the spinal levels comprise at least one targeted dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrodes located on leads, the electrodes placed on separate ones of the at least one targeted dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Placement of each electrode is facilitated by direct visual and/or direct physical access to the targeted dorsal root ganglion.

Abstract: A sonar system is provided including a display screen, a transducer assembly including at least one transducer that is configured to emit one or more sonar signals into an underwater environment and receive sonar return data reflected from one or more objects, and a sonar module configured to generate a 3D matrix based on the sonar return data including a plurality of sonar returns that are each defined by a 3D positional value, determine a group of the plurality of sonar returns associated with an object, assign a predetermined icon to the determined group, and generate and display 3D image of the sonar return data. The predetermined icon is positioned within the 3D image at a position that corresponds to the position of the determined group such that the position of the predetermined icon corresponds to the position of the object.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides various embodiments of neuromodulation systems, and improvements thereof, capable of being implanted at a spinal treatment site and capable of being implanted at the same time and/or in combination with a spinal procedure being performed at the spinal treatment site. The present invention further includes improvements in the number and types of neuromodulation therapies that can be implanted at the spinal treatment site and improvements to the neuromodulation systems used for delivering such neuromodulation therapies.

Abstract: An adjustable weight lifting bench includes a frame, a seat pad, and a back pad. The back pad is pivotably coupled to the frame about a first pivot axis and angularly adjustable between a plurality of user-selectable incline and decline positions. A hydraulic mechanism supports the back pad in the incline and decline positions. A movable operating lever operably coupled to the hydraulic mechanism operates to change the mechanism between an activated condition in which the back pad is movable and a deactivated condition in which the back pad locks into a selected one of the positions. When the mechanism is in activated condition, applying pressure against the back pad the lowers the back pad and removing the pressure raises the back pad. In one embodiment, the mechanism automatically raises the back pad when the pressure is removed and the mechanism is in the deactivated condition.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention comprises implantable neuromodulation systems and methods comprising a protective pouch that at least partially encases an implantable pulse generator prior to implanting in a patient and is adapted to be secured within the surgical site. A lead placement tool configured to receive an electrical lead(s) along at least part of the length of the tool within an open channel or groove to assist in placing electrical leads at the desired target. The lead placement tool may have at least one, or two, angles that provide a bend or angle between first and/or second end regions relative to a straight central region and an open channel along at least one of these regions. A harness for receiving and protecting at least a portion of the length of electrical leads in operative communication with an implantable pulse generator is provided. The harness is adapted to be secured within the surgical site.

Abstract: Methods, apparatuses, and computer program products are therefore provided for producing a 3D image of an underwater environment. An example method for providing an image of an underwater environment includes analyzing sonar returns to identify and display objects, such as fish or debris, in a 3D view. Such an image allows for differentiation between the sea floor and objects in a 3D sonar view. Some example methods provide for real-time tracking of fish. Further, the fish or other objects may be displayed over a continuous surface geometry based on sonar returns from a lake, sea, or river “floor.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that initially comprises spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides a single surgical method, procedure and/or system that creates open visual and physical access to an identified spinal treatment site that comprises both targeted vertebral and spinal levels to be treated, wherein the spinal levels comprise at least one dorsal root ganglion. A spinal treatment procedure is performed generally in combination with implantation of a neuromodulation system that may comprise placement of electrical lead(s) on the at least one dorsal root ganglion, wherein each lead is in operative connection with a pulse generator that may also be implanted during the surgical method. Electrical stimulation may be generated with the pulse generator through the electrical leads to the at least one dorsal root ganglion during and/or after the closure of the identified spinal treatment site.

Abstract: The present invention provides lifitegrast formulations useful for the treatment of immune-related diseases of the ocular surface. The formulations and methods provided herein are particularly useful for treatment of ocular anterior segment tissues.

Abstract: Methods, apparatuses, and computer program products are therefore provided for producing a 3D image of an underwater environment. An example method for providing an image of an underwater environment includes analyzing sonar returns to identify and display objects, such as fish or debris, in a 3D view. Such an image allows for differentiation between the sea floor and objects in a 3D sonar view. Some example methods provide for real-time tracking of fish. Further, the fish or other objects may be displayed over a continuous surface geometry based on sonar returns from a lake, sea, or river “floor.

Abstract: Methods, apparatuses, and computer program products are therefore provided for producing a 3D image of an underwater environment. An example method for providing an image of an underwater environment includes analyzing sonar returns to identify and display objects, such as fish or debris, in a 3D view. Such an image allows for differentiation between the sea floor and objects in a 3D sonar view. Some example methods provide for real-time tracking of fish. Further, the fish or other objects may be displayed over a continuous surface geometry based on sonar returns from a lake, sea, or river “floor.