Patents by Inventor Matthew Joseph

Matthew Joseph has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL-FREE DNA MONITORING
    Publication number: 20230104840
    Abstract: Methods and compositions for monitoring mutation burden, cancer status, vaccine efficacy using cell-free DNA sequencing are disclosed.
    Type: Application
    Filed: July 8, 2022
    Publication date: April 6, 2023
    Applicant: Gritstone bio, Inc.
    Inventors: James Xin Sun, Matthew Joseph Davis, Desiree Schenk, Daniel Navarro Gomez
  • CONTENT BASED IMAGE RETRIEVAL FOR LESION ANALYSIS
    Publication number: 20230106440
    Abstract: Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are commonly used to assess patients with known or suspected pathologies of the lungs and liver. In particular, identification and quantification of possibly malignant regions identified in these high-resolution images is essential for accurate and timely diagnosis. However, careful quantitative assessment of lung and liver lesions is tedious and time consuming. This disclosure describes an automated end-to-end pipeline for accurate lesion detection and segmentation.
    Type: Application
    Filed: December 8, 2022
    Publication date: April 6, 2023
    Inventors: Daniel Irving GOLDEN, Fabien Rafael David BECKERS, John AXERIO-CILIES, Matthieu LE, Jesse LIEMAN-SIFRY, Anitha Priya KRISHNAN, Sean Patrick SALL, Hok Kan LAU, Matthew Joseph DIDONATO, Robert George NEWTON, Torin Arni TAERUM, Shek Bun LAW, Carla Rosa LEIBOWITZ, Angélique Sophie CALMON
  • Multi-layer phase change memory device
    Patent number: 11621394
    Abstract: A phase change memory (PCM) cell comprises a first electrode comprised of a first electrically conductive material, a second electrode comprised of a second electrically conductive material, a first phase change layer positioned between the first electrode and the second electrode and being comprised of a first phase change material, and a second phase change layer positioned between the first electrode and the second electrode and being comprised of a second phase change material. The first phase change material has a first resistivity, the second phase change material has a second resistivity, and wherein the first resistivity is at least two times the second resistivity.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: April 4, 2023
    Assignee: International Business Machines Corporation
    Inventors: Kevin W. Brew, Injo Ok, Jin Ping Han, Timothy Mathew Philip, Matthew Joseph BrightSky, Nicole Saulnier
  • Magnetic sponge assembly
    Patent number: 11602256
    Abstract: A multi-layer sponge assembly is disclosed which contains a magnetic button that mates with a separate magnetic element to allow the sponge to be elevated in a suspended position to dry.
    Type: Grant
    Filed: November 30, 2021
    Date of Patent: March 14, 2023
    Assignee: MUNCHKIN, INC.
    Inventors: Steven Bryan Dunn, Matthew Joseph Saxton, Kwok Ping Kuen
  • Wearable Device Straps and Attachment Hardware Therefor
    Publication number: 20230063140
    Abstract: Low-profile latching mechanisms and related mechanical interfaces for allowing straps and other fastening accessories for limb-wearable devices are provided. The mechanisms in question allow for a very strong, yet easily releasable, connection to be made between a strap accessory and a device housing, with very little of the mechanism being visible.
    Type: Application
    Filed: August 29, 2022
    Publication date: March 2, 2023
    Inventors: Benjamin Patrick Robert Jean Riot, Henry Michael Lubowe, Edison Tam King Miguel, Matthew Joseph Kane, Jr-Jay Jhang, Jens Mitchell Nielsen, Cédric Eric Jean-Edouard Bernard, Brian Dennis Paschke, Junyong Park, Mark Woolhiser Huang, Stephanie Lydia Renee Choplin
  • EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER
    Publication number: 20230056604
    Abstract: The specification relates to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) for use in the treatment of cancer, wherein the EGFR TKI is administered in combination with a Smac mimetic.
    Type: Application
    Filed: January 19, 2021
    Publication date: February 23, 2023
    Inventors: Nicolas FLOCH, Paul David SMITH, Matthew Joseph MARTIN
  • SYSTEMS AND METHODS FOR USING MACHINE LEARNING WITH EPIDEMIOLOGICAL MODELING
    Publication number: 20230051833
    Abstract: Systems and methods of epidemiological modeling using machine learning are provided, and can include receiving values for an occurrence of the infectious disease during a first time period, generating, from a model trained by a machine learning system, predictions for the occurrence of the infectious disease over a second time period, performing, by a simulator using the predictions, one or more simulations of the occurrence of the infectious disease in one or more geographic regions during one or more time periods subsequent to the second time period, and providing, to a user interface, a first simulation of the one or more simulations performed by the simulator for a first geographic region of the one or more geographic regions during a time period of the one or more time periods.
    Type: Application
    Filed: July 28, 2022
    Publication date: February 16, 2023
    Applicant: DataRobot, Inc.
    Inventors: Jeremy Achin, Michael Schmidt, Mackenzie Heiser, Jona Sassenhagen, Oleg Baranovskiy, Jared Shamwell, Hon Nian Chua, Joao Paulo Gomes, Maxence Jeunesse, Yung Siang Liau, Julian Wergieluk, Jay Cameron Schuren, Mark Steadman, Mohak Saxena, Samuel Clark, Noa Flaherty, Jarred Bultema, Nathan Robert Cameron, Amanda Schierz, Vinay Venkata Wunnava, Xavier Conort, Gregory Michaelson, Anton Suslov, Madeleine Mott, Sergey Yurgenson, Christopher James Monsour, Matthew Joseph Nitzken, Patrick Allen Farrell, Jared Bowns, Dustin Burke, Ievgenii Baliuk, Rishabh Raman
  • ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS
    Publication number: 20230041030
    Abstract: Provided herein are target HLA-PEPTIDE antigens, e.g., HLA-PEPTIDE neoantigens and shared tumor HLA-PEPTIDE antigens, and antigen binding proteins (ABPs) that bind the target HLA-PEPTIDE antigens. Also disclosed are methods for identifying target HLA-PEPTIDE antigens as well as identifying one or more antigen binding proteins that bind a given HLA-PEPTIDE target antigen.
    Type: Application
    Filed: May 13, 2022
    Publication date: February 9, 2023
    Inventors: Karin Jooss, Aleksandra Katarzyna Nowicka, Abubakar Jalloh, Roman Yelensky, James Xin Sun, Jennifer Busby, Matthew Joseph Davis
  • Content sharing system and method
    Patent number: 11573678
    Abstract: A content sharing system and method are disclosed. According to certain embodiments, the system may be used in a vehicle. The system may include a user interface and a controller coupled with the user interface. The controller may be configured to display a map of the vehicle on the user interface. The map may show at least a plurality of user devices in the vehicle, and an icon representing content presented by a first user device. The controller may also be configured to detect a user operation moving the icon on the user interface. The controller may further be configured to control, based on the user operation, sharing of the content between the first user device and at least a second user device.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: February 7, 2023
    Assignee: Faraday & Future Inc.
    Inventors: Nicholas William Dazé, Claude P. Meyers, Jennifer Anne Lin, Matthew Joseph Coburn
  • GENERATING ENTITY RISK SCORES AND MITIGATING RISK BASED ON THE RISK SCORES
    Publication number: 20230021423
    Abstract: Techniques for assessing a computing risk of an entity based on a social media footprint of that user. Social media accounts of an entity are identified. Queries are executed against the accounts to determine a social media footprint the entity has based on engagements with those accounts. The footprint reflects at least how much information associated with the entity has been exposed as a result of the engagements with those accounts. Based on the footprint, a risk score for the entity is developed. The risk score reflects a determined amount of computing risk the entity has with regard to potential malicious use of exposed entity information. Based on the risk score, mitigation operations are performed in an attempt to reduce the risk score.
    Type: Application
    Filed: July 20, 2021
    Publication date: January 26, 2023
    Inventors: Michael Angelo DeVico, Matthew Joseph DeVico, Justin Randall Padawer, Taylor Cushman Rose, Richard Edward Horne, Ian James Bell
  • Superalloy part and method of processing
    Patent number: 11559847
    Abstract: A method for repairing a part and the resulting is disclosed. The method includes positioning a plug having an inner braze element coupled thereto into a cavity defined by an internal surface of a component. The cavity has a circular cross-section at the external surface of the component. The plug completely fills the circular cross-section and the inner braze element is within the cavity. A braze paste is positioned at least partially around the plug at the external surface. The component is positioned such that the inner braze element is above the plug. The component is subjected to a thermal cycle to melt the inner braze element around the plug, completely sealing the cavity by forming a metallurgical bond with the plug and the internal surface of the component. During the thermal cycle the braze paste is melted to form a metallurgical bond with the plug and external surface.
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: January 24, 2023
    Assignee: General Electric Company
    Inventors: Yan Cui, Michael Douglas Arnett, Matthew Joseph Laylock, Brian Lee Tollison, Jeffrey Michael Breznak
  • 3D stackable bidirectional access device for memory array
    Patent number: 11562931
    Abstract: A method of manufacturing a vertical metal-semiconductor field-effect transistor (MESFET) device is provided. The method includes forming a first oxide layer, forming a first electrode in the oxide layer, forming a crystallized silicon layer on the first electrode, forming a second electrode on the first oxide layer and on sidewalls of the crystalized silicon layer, forming a second oxide layer on upper surfaces of the second electrode. The method also includes forming a third electrode on an upper surface of the crystallized silicon layer.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: January 24, 2023
    Assignee: International Business Machines Corporation
    Inventors: Fabio Carta, Matthew Joseph BrightSky
  • Surgical Tool Guard
    Publication number: 20230013867
    Abstract: A guard for a tool. The tool is actuatable by a surgical device and has an elongated member and an energy applicator disposed at a distal end of the elongated member. The guard may have a monolithic body including a proximal end and a distal end opposite the proximal end. The proximal end connects to the surgical device. The body further has an interior surface defining a bore extending between the proximal and distal end and the bore adapted to receive the elongated member therethrough and an exterior surface extending between the proximal and distal end and encompassing the interior surface between the proximal and distal end. The body has at least one thermal mitigation channel located between the interior and exterior surfaces and opening through at least one port in the exterior surface.
    Type: Application
    Filed: July 12, 2022
    Publication date: January 19, 2023
    Applicant: MAKO Surgical Corp.
    Inventors: Mark Ellsworth Nadzadi, Andrew Jacob Nelson, Jeremiah Beers, Matthew Joseph Guthart
  • NAVIGATION OF TUBULAR NETWORKS
    Publication number: 20230012778
    Abstract: Methods and apparatuses provide improved navigation through tubular networks such as lung airways by providing improved estimation of location and orientation information of a medical instrument (e.g., an endoscope) within the tubular network. Various input data such as image data, EM data, and robot data are used by different algorithms to estimate the state of the medical instrument, and the state information is used to locate a specific site within a tubular network and/or to determine navigation information for what positions/orientations the medical instrument should travel through to arrive at the specific site. Probability distributions together with confidence values are generated corresponding to different algorithms are used to determine the medical instrument's estimated state.
    Type: Application
    Filed: July 27, 2022
    Publication date: January 19, 2023
    Applicant: Auris Health, Inc.
    Inventors: David S. Mintz, Atiyeh Ghoreyshi, Prasanth Jeevan, Yiliang Xu, Gehua Yang, Matthew Joseph Leotta, Charles V. Stewart
  • SHARED NEOANTIGEN VACCINES
    Publication number: 20230020089
    Abstract: Disclosed herein are compositions that include antigen-encoding nucleic acid sequences and/or antigen peptides. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines, including vectors and methods for a heterologous prime/boost vaccincation strategy.
    Type: Application
    Filed: May 4, 2022
    Publication date: January 19, 2023
    Inventors: Andrew Ferguson, Raphael Rousseau, Roman Yelensky, James Xin Sun, Matthew Joseph Davis, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin, Christine Denise Palmer, Jennifer Busby, Brendan Bulik-Sullivan, Mojca Skoberne, Wade Blair
  • REDUCED MIXING PRESSURE EXCHANGER
    Publication number: 20230020630
    Abstract: A pressure exchanger includes a rotor forming a duct from a first duct opening to a second duct opening. The pressure exchanger further includes a floating piston configured to move within the duct between the first duct opening and the second duct opening to prevent mixing of a first fluid and a second fluid while exchanging pressure between the first fluid and the second fluid. The pressure exchanger further includes a first adapter plate configured to prevent the floating piston from exiting the duct at the first duct opening and a second adapter plate configured to prevent the floating piston from exiting the duct at the second duct opening. The first adapter plate forms a first aperture that directs the first fluid to the first duct opening and the second adapter plate forms a second aperture that directs the second fluid to the second duct opening.
    Type: Application
    Filed: July 6, 2022
    Publication date: January 19, 2023
    Inventors: Omprakash Samudrala, Azam Mihir Thatte, Dung Le Tran, Michael Kjelson, Alexander Patrick Theodossiou, Matthew Joseph Pattom, Farshad Ghasripoor
  • Multi-level cell threshold voltage operation of one-selector-one-resistor structure included in a crossbar array
    Patent number: 11557342
    Abstract: A multi-level cell (MLC) one-selector-one-resistor (1S1R) three-dimensional (3D) cross-point memory system includes at least one MLC 1S1R structure including a stacked arrangement of a phase change memory (PCM) cell and a threshold switch selector. An electrically conductive bit line is in electrical communication with the OTS selector, and an electrically conductive word line is in electrical communication with the PCM cell. A controller is in electrical communication with the bit line and the word line. The controller is configured to select at least one voltage pulse from a group of different voltage pulses comprising a read pulse, a partial set pulse, a set pulse, a partial reset pulse, and a reset pulse, and configured to deliver the selected at least one voltage pulse to the at least one MLC 1S1R structure.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: January 17, 2023
    Assignee: International Business Machines Corporation
    Inventors: Nanbo Gong, Wei-Chih Chien, Matthew Joseph BrightSky, Christopher P. Miller, Hsiang-Lan Lung
  • Pulsing synaptic devices based on phase-change memory to increase the linearity in weight update
    Patent number: 11557343
    Abstract: According to one embodiment, a method, computer system, and computer program product for increasing linearity of a weight update of a phase change memory (PCM) cell is provided. The present invention may include applying a RESET pulse to amorphize the phase change material of the PCM cell; responsive to applying the RESET pulse, applying an incubation pulse to the PCM cell; and applying a plurality of partial SET pulses to incrementally increase the conductance of the PCM cell.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: January 17, 2023
    Assignee: International Business Machines Corporation
    Inventors: Fabio Carta, Matthew Joseph BrightSky, Wanki Kim, Maxence Bouvier, SangBum Kim
  • Content based image retrieval for lesion analysis
    Patent number: 11551353
    Abstract: Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are commonly used to assess patients with known or suspected pathologies of the lungs and liver. In particular, identification and quantification of possibly malignant regions identified in these high-resolution images is essential for accurate and timely diagnosis. However, careful quantitative assessment of lung and liver lesions is tedious and time consuming. This disclosure describes an automated end-to-end pipeline for accurate lesion detection and segmentation.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: January 10, 2023
    Assignee: Arterys Inc.
    Inventors: Daniel Irving Golden, Fabien Rafael David Beckers, John Axerio-Cilies, Matthieu Le, Jesse Lieman-Sifry, Anitha Priya Krishnan, Sean Patrick Sall, Hok Kan Lau, Matthew Joseph Didonato, Robert George Newton, Torin Arni Taerum, Shek Bun Law, Carla Rosa Leibowitz, Angélique Sophie Calmon
  • Compositions Having Low Sulfate Containing Surfactants
    Publication number: 20230000743
    Abstract: The invention is directed to a composition suitable for topical application that comprises a naturally derived preservative having benzoic acid or a derivative thereof. The composition is stable when preserved with the naturally derived preservative and when at a pH that is above the natural pH of skin to as high as 7.25.
    Type: Application
    Filed: August 5, 2022
    Publication date: January 5, 2023
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Kimberly Day, Morgan Nicole Kozar, Matthew Joseph Rienzo, Tirucherai Varahan Vasudevan