Abstract: Disclosed herein are methods and systems for rapid detection of antibiotic resistance of a microorganism in a sample. A modified recombinant phage is also disclosed which comprises an indicator gene in the late gene region. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.

Abstract: A vaporizer device includes various modular components. The vaporizer device includes a first subassembly. The first subassembly includes a cartridge connector that secures a vaporizer cartridge to the vaporizer device and includes at least two receptacle contacts that electrically communicate with the vaporizer cartridge. The vaporizer device includes a second subassembly. The second subassembly includes a skeleton defining a rigid tray that retains at least a power source. The vaporizer device also includes a third subassembly. The third subassembly includes a plurality of charging contacts that supply power to the power source, and an end cap that encloses an end of the vaporizer device.

Abstract: The enclosed disclosure relates to vehicle systems in which an engine, a particulate filter fluidly coupled with the engine, a selective catalytic reduction (SCR) system fluidly coupled with the engine downstream of the particulate filter, an electrical heating device implemented with the particulate filter, and a controller operatively coupled with the engine and the electrical heating device, are implemented. The controller can detect, when the engine is turned off, a condition for turning on the engine, detect a temperature of the particulate filter of the SCR system, activate the electrical heating device in response to the detected temperature being below a lower temperature threshold, and turn on the engine in response to the detected temperature being at or above the lower temperature threshold.

Abstract: The enclosed disclosure relates to vehicle systems in which an engine, a particulate filter fluidly coupled with the engine, a selective catalytic reduction (SCR) system fluidly coupled with the engine downstream of the particulate filter, an electrical heating device implemented with the particulate filter, and a controller operatively coupled with the engine and the electrical heating device, are implemented. The controller can detect, when the engine is turned off, a condition for turning on the engine, detect a temperature of the particulate filter of the SCR system, activate the electrical heating device in response to the detected temperature being below a lower temperature threshold, and turn on the engine in response to the detected temperature being at or above the lower temperature threshold.

Abstract: An exhaust aftertreatment system includes a cross-flow selective catalytic reduction catalyst. The cross-flow selective catalytic reduction catalyst includes a housing and a substrate assembly. The substrate assembly includes a plurality of first substrate layers defining a plurality of first flow channels and a plurality of second substrate layers defining a plurality of second flow channels. The exhaust aftertreatment system includes a passive NOx adsorber. The passive NOx adsorber includes a housing. The housing includes an inlet in exhaust gas receiving communication with the plurality of first flow channels of the cross-flow selective catalytic reduction catalyst. The housing includes an outlet in exhaust gas providing communication with the plurality of second flow channels of the cross-flow selective catalytic reduction catalyst. The passive NOx adsorber includes a substrate positioned in the housing. The substrate includes a passive NOx adsorber washcoat.

Abstract: An exhaust aftertreatment system includes a cross-flow selective catalytic reduction catalyst. The cross-flow selective catalytic reduction catalyst includes a housing and a substrate assembly. The substrate assembly includes a plurality of first substrate layers defining a plurality of first flow channels and a plurality of second substrate layers defining a plurality of second flow channels. The exhaust aftertreatment system includes a passive NOx adsorber. The passive NOx adsorber includes a housing. The housing includes an inlet in exhaust gas receiving communication with the plurality of first flow channels of the cross-flow selective catalytic reduction catalyst. The housing includes an outlet in exhaust gas providing communication with the plurality of second flow channels of the cross-flow selective catalytic reduction catalyst. The passive NOx adsorber includes a substrate positioned in the housing. The substrate includes a passive NOx adsorber washcoat.

Abstract: Continuous skin leading edge slats are disclosed. A disclosed example leading edge slat for use with an aircraft includes a single-piece nose skin defining upper and lower external surfaces of the leading edge slat, where the single-piece nose skin is to extend between a fore end and an aft end of the leading edge slat, and a box spar coupled to an inner surface of the single-piece nose skin. The box spar includes lateral walls extending away from the inner surface of the single-piece nose skin. The lateral walls define at least one compartment of the box spar.

Abstract: The enclosed disclosure relates to vehicle systems in which an engine, a particulate filter fluidly coupled with the engine, a selective catalytic reduction (SCR) system fluidly coupled with the engine downstream of the particulate filter, an electrical heating device implemented with the particulate filter, and a controller operatively coupled with the engine and the electrical heating device, are implemented. The controller can detect, when the engine is turned off, a condition for turning on the engine, detect a temperature of the particulate filter of the SCR system, activate the electrical heating device in response to the detected temperature being below a lower temperature threshold, and turn on the engine in response to the detected temperature being at or above the lower temperature threshold.

Abstract: Continuous skin leading edge slats are disclosed. A disclosed example leading edge slat for use with an aircraft includes a single-piece nose skin defining upper and lower external surfaces of the leading edge slat, where the single-piece nose skin is to extend between a fore end and an aft end of the leading edge slat, and a box spar coupled to an inner surface of the single-piece nose skin. The box spar includes lateral walls extending away from the inner surface of the single-piece nose skin. The lateral walls define at least one compartment of the box spar.

Abstract: An aftertreatment component's shape, entrance geometry, and/or position within an aftertreatment assembly can be modified for local and/or bulk exhaust flow control. In some implementations, a body of the aftertreatment component has a non-circular cross-section, a non-circular opening, and/or a variable face geometry. The non-circular cross-section and/or opening can be of a variety of different shapes.

Abstract: Methods of combining catalytic plates into an assembly of a non-monolithic structure, such as a catalyst substrate or filter assembly, of an exhaust aftertreatment system. A plurality of plates may be disposed within a housing in an arrangement that may define a catalytically active volume of a substrate. Each of the plurality of plates may be single-curved or multiple-curved and/or may be represented by three-dimensional nestable structures. The arrangement of plates may be configured such that the flow is axial, radial, or represented by a hybrid, multi-segment intake path. The plurality of plates may be arranged such that they are configured to receive targeted amounts of coating agent, which may differ among the plates.

Abstract: Currency bills are transported past an image scanner to one or more output receptacles. Each of the bills is imaged to produce image data from which a visually readable image of each bill can be reproduced. The serial number, denomination, and/or secondary identifiers of a bill is attempted to be extracted and/or determined from the image data associated with the bill. The serial number of the bill has an integer number, X, of characters. One or more of the X characters of the serial number of the currency bill is not extracted with a predetermined confidence. In response to failing to extract all of the X characters of the serial number of the bill with the predetermined confidence, a serial number field in an electronic record associated with the bill is populated with a serial number snippet image. The electronic record is stored in a non-transitory memory.

Abstract: An aftertreatment component's shape, entrance geometry, and/or position within an aftertreatment assembly can be modified for local and/or bulk exhaust flow control. In some implementations, a body of the aftertreatment component has a non-circular cross-section, a non-circular opening, and/or a variable face geometry. The non-circular cross-section and/or opening can be a variety of different shapes.

Abstract: Currency bills are transported past an image scanner to one or more output receptacles. Each of the bills is imaged to produce image data from which a visually readable image of each bill can be reproduced. The serial number, denomination, and/or secondary identifiers of a bill is attempted to be extracted and/or determined from the image data associated with the bill. The serial number of the bill has an integer number, X, of characters. One or more of the X characters of the serial number of the currency bill is not extracted with a predetermined confidence. In response to failing to extract all of the X characters of the serial number of the bill with the predetermined confidence, a serial number field in an electronic record associated with the bill is populated with a serial number snippet image. The electronic record is stored in a non-transitory memory.

Abstract: Currency bills are transported past an image scanner to one or more output receptacles. Each of the bills is imaged to produce image data from which a visually readable image of each bill can be reproduced. The serial number, denomination, and/or secondary identifiers of a bill is attempted to be extracted and/or determined from the image data associated with the bill. The serial number of the bill has an integer number, X, of characters. One or more of the X characters of the serial number of the currency bill is not extracted with a predetermined confidence. In response to failing to extract all of the X characters of the serial number of the bill with the predetermined confidence, a serial number field in an electronic record associated with the bill is populated with a serial number snippet image. The electronic record is stored in a non-transitory memory.

Abstract: The present invention concerns methods and compositions regarding one or more microRNAs or variants thereof that are provided to an individual for a variety of medical treatments, including sensitization to cancer therapy or prevention of a cancer to become sensitized to a cancer therapy. In specific embodiments, the microRNAs include miR-520a (including at least miR-520a-3p and miR-520-5p), miR-520g, miR-520h, and functional variants thereof. In some embodiments, the cancer is ovarian cancer, and in particular embodiments, the cancer therapy is platinum-based chemotherapy.

Abstract: The present invention concerns methods and compositions regarding one or more microRNAs or variants thereof that are provided to an individual for a variety of medical treatments, including sensitization to cancer therapy or prevention of a cancer to become sensitized to a cancer therapy. In specific embodiments, the microRNAs include miR-520a (including at least miR-520a-3p and miR-520-5p), miR-520g, miR-520h, and functional variants thereof. In some embodiments, the cancer is ovarian cancer, and in particular embodiments, the cancer therapy is platinum-based chemotherapy.

Abstract: Currency bills are received, transported, and imaged to produce image data from which a visually readable image of each currency bill can be reproduced. Each of the currency bills includes a denomination, a serial number, and a set of secondary identifiers. One of the currency bills is determined to be a suspect bill. The suspect bill serial number is attempted to be extracted from the image data associated with the suspect bill. In response to failing to extract a complete serial number of the suspect bill, a serial number field in a suspect report is populated with a serial number snippet image.

Abstract: A method of processing a deposit transaction includes populating, using a teller terminal, a data file associated with the deposit transaction with a customer account number located on a physical deposit slip associated with the deposit transaction. The deposit slip further includes a total currency bill deposit amount. Physical currency bills associated with the deposit transaction are received in an input receptacle of a document processing device. Each of the received physical currency bills associated with the deposit transaction are denominated using the document processing device to obtain a total value for the physical currency bills. An electronic cash-in ticket image having the total value for the physical currency bills and the customer account number is generated. The electronic cash-in ticket image is used by a proof of deposit system to balance the deposit transaction. The data file is populated with the total value for the physical currency bills.

Abstract: The present invention provides a method of improving a therapeutic response to a cancer treatment, in a subject, the method comprising administering an effective amount of an agent that enhances the expression of microRNA-130 or an agent that mimics the effects of microRNA-130. Further provided is a method of treating a cancer in a subject in need of such treatment comprising the step of administering an effective amount of a microRNA-130 or an agent that enhances the expression of microRNA-130.