Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.

Abstract: Methods of performing assembly or maintenance on an aircraft, systems for performing desired assembly or maintenance on an aircraft, and mobile work stations useful for such systems and methods, where the mobile work stations include a work platform, including an accessway providing access to the work platform; and a moveable base supporting the work platform with one or more platform jacks that can adjustably raise and lower the work platform.

Abstract: Systems and techniques are disclosed to generate programming parameters and modifications during closed-loop adjustment of an implantable neurostimulation device treatment programming, through the identification and application of weights determined from user input indications and rankings of therapy objectives.

Abstract: Systems, devices, and methods for remote monitoring and managing of patients with chronic pain are discussed. A remote monitoring system comprises a cloud-computing device and a remote device. The cloud-computing device receives patient data including physiological or functional information sensed by sensors, and provides on-demand cloud-based services including establishing a correspondence between one or more physiological or functional states and one or more pain levels, detecting patient physiological or functional state, predicting a pain level, detecting a patient behavior, generating a recommendation for adjusting sensor operations based on the patient behavior, and storing patient data and other information in a cloud storage. The remote device can access the cloud storage and the cloud-based services, provide the stored information to an authorized user or the patient, control an implantable device to initiate or adjust a neuromodulation therapy, or adjust sensor operations.

Abstract: Systems, devices, and methods for remote monitoring and managing of patients with chronic pain are discussed. A remote monitoring system comprises one or more sensors to sense physiological or functional information from the patient, a cloud-computing device communicatively coupled to the one or more sensors, and a remote device. The cloud-computing device receives patient data including physiological or functional information, and provides on-demand cloud-based services including storing the received patient data in a cloud storage, detecting a patient behavior, and generating a sensor operation recommendation based on the detected patient behavior. The remote device can access the cloud storage and the cloud-based services, and adjust operations of the one or more sensors in accordance with the sensor operation recommendation.

Abstract: An adapter to add optical stimulation to a stimulation system includes an adapter body and a connector disposed on the distal end of the adapter body. The connector includes a connector body defining a port and a connector lumen; connector contacts disposed in the connector body and arranged along the connector lumen; and a light source disposed in the connector body. The adapter also includes terminals disposed along the proximal end of the adapter body and conductors extending along the adapter body and electrically coupling the connector contacts and the light source to the terminals. The adapter may be used with an optical stylet that fits into a stimulation lead which is, in turn, coupled to the connector of the adapter. Alternatively, the adapter can include a fiber optic coupled to the light source and configured to extend into the stimulation lead.

Abstract: A heating, ventilation, and/or air conditioning (HVAC) system includes a compressor having an impeller configured to rotate and drive a working fluid through a working fluid circuit of the HVAC system in an active operating mode. The HVAC system further includes a controller configured to, in response to receiving an input indicative of a transition to operate in an inactive operating mode, suspend the active operating mode by interrupting a supply of power to the compressor, adjust pre-rotation vanes of the compressor, a variable geometry diffuser of the compressor to a first position, or both to enable a backflow of the working fluid through the compressor for a first interval of time, and, after the first interval of time has elapsed, adjust the pre-rotation vanes, the variable geometry diffuser, or both to a second position to block the backflow of the working fluid through the compressor.

Abstract: The present disclosure relates to a novel tetrazole azasydnone, a method of making the novel tetrazole azasydnone, and a method of using the novel tetrazole azasydnone as a primary explosive. In one aspect, the novel tetrazole azasydnone has a structure of formula I: wherein A? represents a cation with a 1+ charge.

Abstract: A stimulation system includes a device programmed with user-specified routines for operation of a pulse generator, where the user-specified routines are activatable in response to information received from a source external to the pulse generator, The device includes a memory, a communication unit, and at least one processor coupled to the memory and the communication unit and configured to perform actions, including receiving, using the communication unit, information provided from the source external to the pulse generator and external to the patient, when the information meets an activation criterion for a one of the user-specified routines, activating the user-specified routine to deliver or halt delivery of stimulation to the patient according to the user-specified routine, and upon completion of the user-specified routine or meeting a termination condition, halting the user-specified routine.

Abstract: A turbine engine having an engine core, a first seal structure, a plurality of circumferentially arranged vanes, a plurality of struts, and a second seal structure. The engine core can define a rotor and a stator having a casing. The first seal structure can include a finger seal projecting from the rotor. The plurality of circumferentially arranged vanes can include an uppers band mounted to the casing, and a lower band located radially above the finger seal. At least some of the struts of the plurality of struts can extend through the plurality of circumferentially arranged vanes. The second seal structure can form a seat with the lower band.

Abstract: A test system (110) for determining battery performance during development of a battery configuration in a test environment is proposed. The test system (110) comprises at least one communication interface (114) and at least one processing device (122). The test system (110) is configured for receiving operating data indicative of at least one test protocol via the communication interface (114). The test system (110) is configured for receiving battery performance input data via the communication interface (114). The processing device (122) is configured for determining at least one predicted time series of at least one state variable indicative of battery performance based on the battery performance input data and on the operating data using at least one data driven model. The test system (110) is configured for providing at least parts of the predicted time series of the state variable.

Abstract: Systems and methods are disclosed for processing digital images to predict at least one continuous value comprising receiving one or more digital medical images, determining whether the one or more digital medical images includes at least one salient region, upon determining that the one or more digital medical images includes the at least one salient region, predicting, by a trained machine learning system, at least one continuous value corresponding to the at least one salient region, and outputting the at least one continuous value to an electronic storage device and/or display.

Abstract: Systems and methods are described that include receiving, in a tab strip generated by a web browser application, a request to generate a tab group, generating the tab group, in response to receiving the request, where the generating includes generating a tab group identifier for the tab group, enabling pausing or starting of an activity associated with a resource accessed by a browser tab within the tab group based on whether the tab group is collapsed or expanded, and storing metadata about the tab group and the browser tab included in the tab group. The systems and methods may further include causing display of the generated tab group in the tab strip with the tab group identifier depicted in at least a portion of a user interface associated with the browser tab where the generated tab group is configured for display based on the metadata.

Abstract: According to an aspect, an implantable device for penile construction includes a penile implant having a distal portion and a proximal portion. The distal portion includes a shaft portion configured to be disposed in a neophallus. The proximal portion defines a first strut and a second strut, and the proximal portion is configured to be attached to a pelvis structure.

Abstract: A method implemented by a processor of a device, the method including determining one or more user values, determining a prompt requiring a decision, and receiving a user selection to one or more choice options related to the one or more user values and pertaining to the prompt requiring a decision. The method further includes comparing the user selection to a risk-neutral utility function and assessing a risk of a potential decision based on the comparison.

Abstract: A server (10), a server rack (50) and a data centre (100, 150) are provided. The server (10) includes a housing (12) defining a gaseous flow passage. A plurality of active components (14) and a plurality of passive components (16) are provided in the housing (12). A plurality of liquid cooling devices (18) is attached to respective ones of the active components (14).

Abstract: A device for selectively connecting mobile medical equipment, such as an IV pole, to a patient transport platform such that the medical equipment and patient transport platform can move together, thus providing a patient mobility while maintaining the patient's connection to the mobile medical equipment and therefore eliminating the necessity to disconnect an existing medical equipment (such as IV pole) and transfer the patient to a new medical equipment, while also allowing monitoring of patient movement and activity via electronics in the device.

Abstract: Methods and apparatus relating to processor and chipset continuity testing of package interconnect for functional safety applications are described. In an embodiment, voltage divider logic circuitry divides a reference voltage. Controller logic circuitry compares a divided voltage value from a node of the voltage divider logic circuitry and a threshold voltage value. A first end of the voltage divider logic circuitry is coupled to receive the reference voltage and a second end of the voltage divider logic circuitry is coupled to a Non-Critical-To-Function (NCTF) solder ball. The controller logic circuitry generates an error signal in response to a mismatch between the divided voltage value and the threshold voltage value. Other embodiments are also disclosed and claimed.

Abstract: Embodiments include computer implemented methods for generating a real-time personalized graduated evaluation metric associated with listings being displayed in a web browser. A user account can be authenticated by sending a set of login credentials to an authentication server and receiving an authentication token including user information. Web-based content can be displayed in the web browser application to determine that the web-based content corresponds to a listing page. A purchase metric can be generated for the listing based on a first set of listing data, a second set of listing data obtained using the first set of listing data, and the user information. A graduated evaluation metric can be selected based on the purchase metric satisfying a threshold associated with a first graduated evaluation metric and causing a web browser application to display a popup window containing a graduated visual indicia corresponding to the graduated evaluation metric.

Abstract: Electronic devices and methods for displaying information on electronic displays of electronic devices based on learned user behavior are disclosed. In one embodiment, an electronic device includes an electronic display, a processor, and a non-transitory computer-readable medium storing instructions that, when executed by the processor, causes the processor to cause for display on the electronic display a selected representation of information among a plurality of representations based at least in part on learned behavior of a user.