Abstract: Embodiments of the invention is directed to methods of forming a bone-like material, by placing a matrix into a culture container, adding cells to the matrix, placing the tissue-cell construct into the culturing environment and incubating the construct under appropriate conditions for the time required to produce an amount of bone-like material of sufficient volume to be harvested for further processing. Other embodiments of the invention are directed to the use of the bone-like material formed by methods of the invention in implantation procedures.

Abstract: A multipurpose weather measurement instrument sensor system in which a fan circulates air past temperature and other sensors to ensure their accurate operation, a basin collects rainwater and precisely directs the rainwater into a tipping receptacle to measure the amount of rainwater collected per unit time and a wind speed gauge is provided with a counter-balanced toggle beam to product wobble-free rotation.

Abstract: A device for sealing an aperture in a tissue includes: an implant configured to seal the aperture when positioned adjacent to the aperture; and a delivery shaft configured to engage the implant to allow the implant to be maneuvered into sealing engagement with a distal surface of the tissue, the delivery shaft comprising a retaining sleeve comprising a locking projection engagable with the locking recess of the implant to secure the implant to the delivery shaft, and a release sleeve axially slideable relative to the retaining sleeve between a first axial position in which the release sleeve is configured to maintain locking engagement between the locking recess and the locking projection, and a second axial position in which the release sleeve permits the locking projection to disengage the locking recess.

Abstract: The invention comprises a combination of biological elements that will naturally remodel in vivo based on applied mechanical forces. The final composition will possess mechanical properties similar to cartilage or a disc, and significantly less stiff than bone or implants comprised of metals or plastics. The equilibrium stress conduction will minimize unnatural forces on neighboring healthy discs.

Abstract: A device for delivering an implant configured to seal an aperture in a tissue includes: a delivery shaft configured to engage the implant to allow the implant to be maneuvered into sealing engagement with a distal surface of the tissue, the delivery shaft comprising a retaining sleeve comprising a locking projection engagable with a locking recess of the implant to secure the implant to the delivery shaft, and a release sleeve axially slideable relative to the retaining sleeve between a first axial position in which the release sleeve is configured to maintain locking engagement between the locking recess and the locking projection, and a second axial position in which the release sleeve permits the locking projection to disengage the locking recess.

Abstract: An insert for a protective garment, the insert having a fabric having at least 45 percent by weight of expanded polytetrafluoroethylene fibers, the fabric having a 2-Grain V-50 Fragmentation Resistance of at least 700 feet per second and a FAST-2 Bending Rigidity of less than 40 microNewtonmeters.

Abstract: A flow through fluid sampling system includes a sample tube and a cap. The sample tube is configured to collect a sample of a fluid and has an open top. The cap is configured to be secured to the sample tube to close the open top. The cap includes an inflow port configured to allow fluid to enter the fluid sample tube, an outflow port configured to allow fluid to leave the sample tube.

Abstract: The invention is directed to a work station for use in performing processing of patient samples, storing equipment and drugs in a hospital and the like, the cart having a lower housing having caster wheels mounted on the bottom thereof, the lower housing having angular-shaped side panels therearound which may be opened for entrance into all sides of the housing, and one or more of the side panels; an upper housing mounted on top of the lower housing, the upper housing having one or more side panels therearound; and one or more work areas mounted on top of the upper housing, the shelf adapted for receiving point-of-care equipment.

Abstract: The invention is directed to a bone void filler comprising a scaffold or matrix. The scaffold or matrix may include a porous inorganic matrix component and/or a 3D-printed implantable device. The bone void filler may include a cellular component containing cells, some of which are capable of making extracellular matrix resembling native bone tissue. The bone void filler may include an organic matrix, such as, an organic biopolymer that aids in cell retention and renders the scaffold or matrix moldable. The bone void filler may include growth factors and/or cytokines. The bone void filler may include a clotting agent.

Abstract: The invention is directed to a therapeutic composition that includes a first cell preparation that includes isolated stromal cells of a first type and a second cell preparation that includes isolated stromal cells of a second type. The first and second cell preparations may include cultured cells. The stromal cells may include adipose stromal cells and bone marrow derived stromal cells. The therapeutic composition may include a blood component that includes one or more of platelet-poor plasma, concentrated platelet-poor plasma, platelet-rich plasma, and whole blood.

Abstract: The invention is directed to a method for isolating stromal cells to form a therapeutic composition; and administering said therapeutic composition to the subject. A further embodiment of the invention is directed to therapeutic compositions comprising isolated stromal cells.

Abstract: The invention is directed to a bone void filler comprising a scaffold or matrix. The scaffold or matrix may include a porous inorganic matrix component. The bone void filler may include a cellular component containing cells, some of which are capable of making extracellular matrix resembling native bone tissue. The bone void filler may include an organic matrix, such as, an organic biopolymer that aids in cell retention and renders the scaffold or matrix moldable. The bone void filler may include growth factors and/or cytokines. The bone void filler may include a clotting agent.

Abstract: A method and apparatus for sharing data regarding conditions sensed at one or more user-selected locations with others over the Internet generally or over Internet-accessed social networking systems using sensors located at user-selected locations and servers which are connected respectively to the Internet for communication with client devices or with social networking systems.

Abstract: A method, apparatus, and system of interaction between groups surrounding a present geo-spatial location of a mobile device are disclosed. In one embodiment, a method of a geo-spatial groups server includes verifying a particular user based on a verification code of the particular user placed through a mobile device communicatively coupled to the geo-spatial groups server. The method creates a group tied to geo-spatial vicinity surrounding a current geo-spatial location of the mobile device. The method associates a name identifier to the group and also permits a different user in the geo-spatial vicinity surrounding the current geo-spatial location of the mobile device to access the group. Further, the method automatically denies a requester user access to the group when the requestor user is outside an outer boundary of the geo-spatial vicinity surrounding the current geo-spatial location of the mobile device.

Abstract: A portable, temporary removable system for locking and unlocking a door knob, door lever or locking deadbolt without the requirement of using keyed entry. Several manners of automated locking and unlocking are introduced and the instant system is designed for quick installation and removal. Once attached, the system may be remotely controlled from the outside of the door via a pattern of knocks, via electronic communications or a combination of a knock pattern and electronic communication.

Abstract: A device for folding an implant having a wing into a an overlapped configuration includes a funnel body comprising: a first portion configured to receive and protect the implant when the wing of the implant is in a flat or relaxed state, a second portion proximal to the first portion and configured to engage and fold opposite first and second side portions of the wing of the implant in a predetermined direction when the implant is retracted proximally from the first portion of the funnel body and into the second portion of the funnel body, and an overlap guide configured to direct the path of a first one of the side portions of the wing such that the first and second side portions of the wing are overlapped in a predetermined manner and to prevent respective edges of the first and second side portions of the wing from butting into each other as the first and second side portions of the wing are guided into the overlapping configuration during proximal retraction of the implant relative to the funnel body.

Abstract: A method for washing platelets includes introducing anticoagulant into a platelet product container, drawing re-anticoagulated platelet product from the platelet product container, and introducing it into a centrifuge bowl. The centrifuge bowl separates the platelets from the supernatant in which they are suspended. The method then washes the platelets by introducing wash solution into the centrifuge bowl. As the wash solution is introduced into the bowl, it displaces the supernatant from the bowl and into a waste container. The method then introduces platelet additive solution into the centrifuge bowl, which displaces the wash solution from the centrifuge bowl and into the waste container and further wash the platelets. The method then repeatedly accelerates and decelerates the centrifuge bowl to resuspend the platelets in the platelet additive solution.

Abstract: A method for washing platelets includes introducing anticoagulant into a platelet product container, drawing re-anticoagulated platelet product from the platelet product container, and introducing it into a centrifuge bowl. The centrifuge bowl separates the platelets from the supernatant in which they are suspended. The method then washes the platelets by introducing wash solution into the centrifuge bowl. As the wash solution is introduced into the bowl, it displaces the supernatant from the bowl and into a waste container. The method then introduces platelet additive solution into the centrifuge bowl, which displaces the wash solution from the centrifuge bowl and into the waste container and further wash the platelets. The method then repeatedly accelerates and decelerates the centrifuge bowl to resuspend the platelets in the platelet additive solution.

Abstract: A pipe straightening apparatus comprising a first set of rotatably mounted elements which define, at least in part, a first passageway through which a pipe can be constrained to pass, so as to straighten the pipe, wherein the first set of rotatably mounted elements are arranged such that when a pipe translates within the first passageway, relative to the apparatus, the first set of rotatably mounted elements roll along the pipe, relative to the pipe, in a direction which has a component in the circumferential direction of the pipe and a second set of rotatably mounted elements which define, at least in part, a second passageway through which a pipe can pass, wherein the second set of rotatably mounted elements are arranged such that when a pipe translates within the second passageway, relative to the apparatus, the second set of rotatably mounted elements roll along the pipe, relative to the pipe, in a direction that is substantially parallel to the longitudinal axis of the pipe.

Abstract: A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.