Abstract: The transgenic plants expressing one or more antagonist IL-10R peptides and anti-IL-10 single domain antibodies that stimulate or modulate the immune system and improve gastrointestinal physiology of an animal fed the transgenic plants or tissues thereof and the genes encoding the antagonist IL-10R peptides and anti-IL-10 single domain antibodies are described. The animal feed additives and animal feed incorporating the transgenic plants or tissues thereof are also described. Methods of stimulating or modulating an animal's immune system, improving an animal's gastrointestinal physiology, improving animal performance by using the transgenic plants or tissues thereof, and treating animals infected with a gastrointestinal pathogen are provided.

Abstract: To improve the operation of 3D printing systems, techniques are disclosed for a rotary 3D printer comprising: a main rotating support table rotating about a first axis and one or more secondary support tables rotating around a non-coaxial secondary axis; a powder supply assembly for distributing powder onto the tables; and an energy system for directing an energy beam at the powder to form a part. The main support table and secondary support tables can rotate in the same or opposite directions. Disclosed techniques include: grooved support table surfaces for improving stability of applied powder; reciprocating bellows for controlling a differential load on actuators that move the support tables; high temperature bearings or bushings for supporting rotary motion at high temperatures; and a mechanism for counterbalancing a weight of the part being built.

Abstract: The invention relates to processes for performing biochemical reactions, such as in an aqueous in vitro reaction system. The processes involve macromolecules, particularly polypeptides, comprising one or more functional intrinsically disordered regions (IDRs). The invention also relates to IDR-macromolecules, including IDR-polypeptides, including macromolecules or polypeptides comprising a tagged amino acid sequence which comprises or consists of one or more functional IDRs. Such functional IDRs are capable of increasing the efficiency of the biochemical reaction. The invention relates to kits comprising any such macromolecules and polypeptides. The invention further relates to processes for stimulating or enhancing liquid-liquid demixing in a solution using any such macromolecules and polypeptides, including in combination with multivalent metal ions, thereby providing reagents capable of increasing the efficiency of a biochemical reaction.

Abstract: Apparatus include a reaction mass and an actuator coupled to the reaction mass. The actuator is configured to couple to a payload and to move the reaction mass in response to a movement error of the payload to reduce the movement error of the payload. Robotic systems using actuated reaction masses, as well as related methods of reducing movement errors, are also disclosed.

Abstract: The problem of addressing vibrational disturbances in mechanical positioning systems is addressed by systems and methods that use a combination of active vibration dampening and passive vibration dampening. A system described herein generally comprises a mechanical positioning system; a payload; and a vibration dampening module coupled to the mechanical position system and to the payload. The vibration dampening module generally comprises an active vibration dampener and/or a passive vibration dampener.

Abstract: A vibration reduction assembly (24) for reducing a magnitude of a vibration being transferred from a first component (14) (e.g. a robot assembly) to a second component (12) (e.g. a payload) includes a first vibration reduction system (30) and a second vibration reduction system (32). The first vibration reduction system (30) reducing vibration along a first axis that is oriented parallel with gravity. The second vibration reduction system (32) reducing vibration along a second axis that is orthogonal to the first axis. The first vibration reduction system (30) and the second vibration reduction system (32) are connected in series between the first component (14) and the second component (12).

Abstract: The invention relates to processes for performing biochemical reactions, such as in an aqueous in vitro reaction system. The processes involve macromolecules, particularly polypeptides, comprising one or more functional intrinsically disordered regions (IDRs). The invention also relates to IDR-macromolecules, including IDR-polypeptides, including macromolecules or polypeptides comprising a tagged amino acid sequence which comprises or consists of one or more functional IDRs. Such functional IDRs are capable of increasing the efficiency of the biochemical reaction. The invention relates to kits comprising any such macromolecules and polypeptides. The invention further relates to processes for stimulating or enhancing liquid-liquid demixing in a solution using any such macromolecules and polypeptides, including in combination with multivalent metal ions, thereby providing reagents capable of increasing the efficiency of a biochemical reaction.

Abstract: Positioning assemblies for use with a robot include a gimbal assembly having a gimbal's rotational center is positioned directly above a center of gravity of a payload. One or more linear counter masses and/or one or more rotating masses (flywheels) can be provided, and each can include an actuator or brake to control forces acting between the counter masses and/or flywheels and the payload and stabilize the payload during and after movement of the payload with the robot.

Abstract: A sealed joint assembly for transmitting high temperature and high pressure fluid between adjoining ducts in, for example, an aircraft bleed air system, includes a gimbal ring and two annular clevises. Each clevis includes a pair of axially-extending lobes that each includes a bore hole extending therethrough. The bore holes of the clevis lobes may each align with a respective bore hole formed within the gimbal ring, through which a pin may be inserted to couple the clevises to the gimbal ring. The clevises and gimbal ring may be formed using additive manufacturing, and may be optimized to reduce the joint assembly's overall weight, while maintaining or improving its structural integrity. The gimbal ring may include a strut or truss network to enhance structural integrity, and may be comprised of an inner gimbal ring and an outer gimbal ring.

Abstract: This invention relates to a pre-portioned single, multiple, or fractional serving(s) in effervescent tablet form, containing doses of stimulants, amino acids, vitamins, and minerals in unique quantities to enhance performance of exercise related activities. The composition and delivery of these components is unique and solves problems pertaining to the traditional packaging, composition, and delivery methods used for these products. This invention provides a product that can serve as a pre-workout stimulant, energy aid, or exercise related improvement supplement that is delivered in effervescent tablet form.

Abstract: A platform for providing projections, predictions, and recommendations for casino and gaming environments. The platform leverages machine learning and cognitive computing. Through a natural language interface, the platform presents this information in a way which is natural and timely for casino operational executives to understand and act upon. The platform can optimize gaming machine performance casino floor performance based on various metrics that are predicted by the platform.

Abstract: A fuel control system can operate an internal combustion engine to selectively combust a first fuel, such as diesel, during a single fuel mode and to combust the first fuel and a second fuel, such natural gas, during a fuel substitution mode. An in-cylinder parameter sensor is in communication with the combustion chamber of the internal combustion engine to measure an in-cylinder parameter such as, for example, the indicated mean effective pressure, during combustion of the first fuel during the single fuel mode. The fuel control system utilizes the in-cylinder parameter to determine a first fuel quantity error and can adjust delivery of the first fuel to correct for the first fuel quantity error during the single fuel and fuel substitution modes. The fuel control system can also use the first fuel quantity error to determine and adjust for a second fuel quantity error.

Abstract: A sealed joint assembly for transmitting high temperature and high pressure fluid between adjoining ducts in, for example, an aircraft bleed air system, includes a gimbal ring and two annular clevises. Each clevis includes a pair of axially-extending lobes that each includes a bore hole extending therethrough. The bore holes of the clevis lobes may each align with a respective bore hole formed within the gimbal ring, through which a pin may be inserted to couple the clevises to the gimbal ring. The clevises and gimbal ring may be formed using additive manufacturing, to produce component geometries and topologies that reduce the overall weight of the joint assembly while maintaining or improving its structural integrity. For example, the clevis lobes may include a plurality of gaps, such that the remaining material forms a shear web. The gimbal ring may also include strut or truss networks to enhance structural integrity.

Abstract: A processing machine (10) for building a part (11) includes: a support device (26) including a support surface (26B); a drive device (28) which moves the support device (26) so as a specific position on the support surface (26B) is moved along a moving direction (25); a powder supply device (18) which supplies a powder (12) to the moving support device (26) to form a powder layer (13); an irradiation device (22) which irradiates at least a portion of the powder layer (13) with an energy beam (22D) to form at least a portion of the part (11) from the powder layer (13) during a first period of time; and a measurement device (20) which measures at least portion of the part (11) during a second period of time. The first period in which the irradiation device (22) irradiates the powder layer (13) with the energy beam (22D) and the second period in which the measurement device (22) measures are overlapped.

Abstract: Access points for a baggage message handling system, baggage message handling systems, and methods associated with message communication in a baggage message handling system. The system includes an input/output interface suitable for connecting to an external system, a converter configured to convert a message received via the input/output interface and/or a message to be transmitted via the input/output interface into a predetermined format, an extractor configured to extract metadata from a converted message, and a transmit and/or receive unit configured to transmit and/or receive a further message including extracted metadata and associated address information.

Abstract: The transgenic plants expressing one or more antagonist IL-10R peptides and anti-IL-10 single domain antibodies that stimulate or modulate the immune system and improve gastrointestinal physiology of an animal fed the transgenic plants or tissues thereof and the genes encoding the antagonist IL-10R peptides and anti-IL-10 single domain antibodies are described. The animal feed additives and animal feed incorporating the transgenic plants or tissues thereof are also described. Methods of stimulating or modulating an animal's immune system, improving an animal's gastrointestinal physiology, improving animal performance by using the transgenic plants or tissues thereof, and treating animals infected with a gastrointestinal pathogen are provided.

Abstract: Methods are disclosed for delivering energy to a body of a human or animal during a treatment procedure using an electrosurgical generator, a pre-set overall procedure time being defined for the treatment procedure, a ramp time being defined for a parameter to reach a pre-set threshold during the treatment procedure, the method comprising: measuring the parameter over time; and if the parameter has not substantially reached the pre-set threshold by the ramp time, setting a procedure extension time responsive to the time difference between the ramp time and the time at which the pre-set threshold was reached, and extending the overall procedure time by the procedure extension time.

Abstract: Systems and methods that help ensure that assist a user with bill payment on a graphical user interface (GUI) are described. After receiving bill payment information from the user through the GUI, bill payments are aggregated over a given period of time, allowing a user to make a single payment to ensure that all appropriate bills and/or invoices are paid in a timely fashion. Through use of the GUI, a user can avoid the traditional hassle and stress of tracking and paying bills.

Abstract: A platform for providing projections, predictions, and recommendations for casino and gaming environments. The platform leverages machine learning and cognitive computing. Through a natural language interface, the platform presents this information in a way which is natural and timely for casino operational executives to understand and act upon. The platform can optimize gaming machine performance casino floor performance based on various metrics that are predicted by the platform.

Abstract: The invention describes a vitamin receptor binding drug delivery conjugate, and preparations therefor. The drug delivery conjugate consists of a vitamin receptor binding moiety, a bivalent linker (L), and a drug. The vitamin receptor binding moiety includes vitamins, and vitamin receptor binding analogs and derivatives thereof, and the drug includes analogs and derivatives thereof. The vitamin receptor binding moiety is covalently linked to the bivalent linker, and the drug, or the analog or the derivative thereof, is covalently linked to the bivalent linker, wherein the bivalent linker (L) includes components such as spacer linkers, releasable linkers, and heteroatom linkers, and combinations thereof. Methods and pharmaceutical compositions for eliminating pathogenic cell populations using the drug delivery conjugate are also described.