Patents by Inventor Matthew Parker
Matthew Parker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8865126Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid of the formula H2NCHRCOOH, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.Type: GrantFiled: October 18, 2012Date of Patent: October 21, 2014Assignee: Endocyte, Inc.Inventors: Christopher P. Leamon, Matthew A. Parker
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Patent number: 8834842Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.Type: GrantFiled: March 11, 2013Date of Patent: September 16, 2014Assignee: Endocyte, Inc.Inventors: Christopher P. Leamon, Matthew A. Parker
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Publication number: 20140069026Abstract: In a rostrum, comprising a rostrum support structure comprising a plurality of frame units; the frame units comprising at least a first frame unit, a second frame unit which is retractable in a retraction direction from an extended position into the first frame unit, and a third frame unit, which is retractable in the retraction direction from an extended position into the second frame unit, a latching mechanism is provided which is configured so that the third frame unit cannot be retracted from the extended position into the second frame unit until the second frame unit has been retracted from the extended position into the first frame unit. A respective deck is engaged with each respective frame unit.Type: ApplicationFiled: September 11, 2012Publication date: March 13, 2014Inventor: Nigel Matthew Parker
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Publication number: 20140058063Abstract: The invention describes a vitamin receptor binding drug delivery conjugate, and preparations therefor. The drug delivery conjugate consists of a vitamin receptor binding moiety, a bivalent linker (L), and a drug. The vitamin receptor binding moiety includes vitamins, and vitamin receptor binding analogs and derivatives thereof, and the drug includes analogs and derivatives thereof. The vitamin receptor binding moiety is covalently linked to the bivalent linker, and the drug, or the analog or the derivative thereof, is covalently linked to the bivalent linker, wherein the bivalent linker (L) includes components such as spacer linkers, releasable linkers, and heteroatom linkers, and combinations thereof. Methods and pharmaceutical compositions for eliminating pathogenic cell populations using the drug delivery conjugate are also described.Type: ApplicationFiled: March 5, 2013Publication date: February 27, 2014Applicant: ENDOCYTE, INC.Inventors: Iontcho R. Vlahov, Christopher P. Leamon, Matthew A. Parker, Stephen J. Howard, Hari Krishna R. Santhapuram, Apparao Satyam, Joseph A. Reddy
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Publication number: 20130255414Abstract: A stage apparatus includes at least one tube having a first section and a second section, the first section being coupled to a point of reference. The apparatus also includes at least one magnet, a precision stage, and a tube carrier. The precision stage is positioned at least partially over the at least one magnet, and has a first set of coils. The first set of coils cooperates with the at least one magnet to drive the precision stage. The tube carrier is at least partially positioned over the at least one magnet, and includes an end effector portion arranged to carry the second section, wherein the tube carrier further includes a second set of coils, the second set of coils being supported by the end effector portion and arranged to cooperate with the at least one magnet to control motion of the end effector portion.Type: ApplicationFiled: September 8, 2011Publication date: October 3, 2013Applicant: Nikon CorporationInventors: Matthew Parker-McCormick Bjork, Michael B. Binnard, Scott Coakley
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Publication number: 20130237687Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid of the formula H2NCHRCOOH, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.Type: ApplicationFiled: October 18, 2012Publication date: September 12, 2013Applicant: ENDOCYTE, INC.Inventors: Christopher P. LEAMON, Matthew A. Parker
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Patent number: 8343146Abstract: Embodiments of a system and method are described for delivering energy to a body of a human or animal through a plurality of energy delivery devices. In some embodiments, a plurality of energy delivery devices are coupled to a generator and the number of energy delivery devices is automatically detectable. Furthermore, in some embodiments, the amount of energy delivered through the energy delivery devices is controlled, at least in part, by dynamically varying the amount of time that each energy delivery device is delivering energy.Type: GrantFiled: February 25, 2008Date of Patent: January 1, 2013Assignee: Kimberly-Clark Inc.Inventors: Neil Godara, Taylor Hillier, Matthew Parker, Jason Woo
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Patent number: 8313728Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid of the formula H2NCHRCOOH, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.Type: GrantFiled: September 11, 2009Date of Patent: November 20, 2012Assignee: Endocyte, Inc.Inventors: Christopher P. Leamon, Matthew A. Parker
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Patent number: 8298263Abstract: The technology disclosed herein provides a device, system, and method for weaning a child off a sucking device, such as a pacifier, by introducing a series of sucking devices with successively smaller nubs. A child is given a first sucking device having a nub of a certain size, and, after a time period, the child is given a second sucking device having a nub smaller than that of the first sucking device. This method may be repeated in multiple iterations, until the child is weaned off sucking devices.Type: GrantFiled: September 9, 2009Date of Patent: October 30, 2012Assignee: TinkLab, LLCInventors: Matthew Parker, Timothy Ramundo
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Publication number: 20120065149Abstract: The invention describes a vitamin receptor binding drug delivery conjugate, and preparations therefor. The drug delivery conjugate consists of a vitamin receptor binding moiety, a bivalent linker (L), and a drug. The vitamin receptor binding moiety includes vitamins, and vitamin receptor binding analogs and derivatives thereof, and the drug includes analogs and derivatives thereof. The vitamin receptor binding moiety is covalently linked to the bivalent linker, and the drug, or the analog or the derivative thereof, is covalently linked to the bivalent linker, wherein the bivalent linker (L) includes components such as spacer linkers, releasable linkers, and heteroatom linkers, and combinations thereof. Methods and pharmaceutical compositions for eliminating pathogenic cell populations using the drug delivery conjugate are also described.Type: ApplicationFiled: September 7, 2011Publication date: March 15, 2012Inventors: Iontcho R. Vlahov, Christopher P. Leamon, Matthew A. Parker, Stephen J. Howard, Hari Krishna Santhapuram, Apparao Satyam, Joseph Anand Reddy
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Patent number: 8105568Abstract: The invention describes a vitamin receptor binding drug delivery conjugate, and preparations therefor. The drug delivery conjugate consists of a vitamin receptor binding moiety, a bivalent linker (L), and a drug. The vitamin receptor binding moiety includes vitamins, and vitamin receptor binding analogs and derivatives thereof, and the drug includes analogs and derivatives thereof. The vitamin receptor binding moiety is covalently linked to the bivalent linker, and the drug, or the analog or the derivative thereof, is covalently linked to the bivalent linker, wherein the bivalent linker (L) includes components such as spacer linkers, releasable linkers, and heteroatom linkers, and combinations thereof. Methods and pharmaceutical compositions for eliminating pathogenic cell populations using the drug delivery conjugate are also described.Type: GrantFiled: July 10, 2009Date of Patent: January 31, 2012Assignee: Endocyte, Inc.Inventors: Iontcho R. Vlahov, Christopher P. Leamon, Matthew A. Parker, Stephen J. Howard, Hari Krishna R. Santhapuram, Apparao Satyam, Joseph A. Reddy
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Publication number: 20110063418Abstract: A device is described which allows convenient acquisition of stereoscopic video. In accordance with one embodiment, a rigid mounting bar is provided on which two camcorders can be mounted. The bar has mounting slots or other means to provide for adjustment of the distance between the two cameras. An electronic synchronization and control circuit is contained within the mounting bar. This circuit synchronizes the two camcorders quickly so that each video frame is acquired simultaneously by the two camcorders.Type: ApplicationFiled: August 4, 2010Publication date: March 17, 2011Inventor: Matthew A. Parker
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Patent number: 7862798Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid of the formula H2NCHRCOOH, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.Type: GrantFiled: October 11, 2006Date of Patent: January 4, 2011Assignee: Endocyte, Inc.Inventors: Christopher P. Leamon, Matthew A. Parker
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Publication number: 20100324548Abstract: Embodiments of a system and method are described for delivering energy to a body of a human or animal through a plurality of energy delivery devices. In some embodiments, a plurality of energy delivery devices are coupled to a generator and the number of energy delivery devices is automatically detectable. Furthermore, in some embodiments, the amount of energy delivered through the energy delivery devices is controlled, at least in part, by dynamically varying the amount of time that each energy delivery device is delivering energy.Type: ApplicationFiled: February 25, 2008Publication date: December 23, 2010Applicant: BAYLIS MEDICAL COMPANY INC.Inventors: Neil Godara, Taylor Hillier, Matthew Parker, Jason Woo
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Publication number: 20100069959Abstract: The technology disclosed herein provides a device, system, and method for weaning a child off a sucking device, such as a pacifier, by introducing a series of sucking devices with successively smaller nubs. A child is given a first sucking device having a nub of a certain size, and, after a time period, the child is given a second sucking device having a nub smaller than that of the first sucking device. This method may be repeated in multiple iterations, until the child is weaned off sucking devices.Type: ApplicationFiled: September 9, 2009Publication date: March 18, 2010Applicant: TINKLAB, LLCInventors: Matthew Parker, Timothy Ramundo
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Publication number: 20100004276Abstract: The invention describes a vitamin receptor binding drug delivery conjugate, and preparations therefor. The drug delivery conjugate consists of a vitamin receptor binding moiety, a bivalent linker (L), and a drug. The vitamin receptor binding moiety includes vitamins, and vitamin receptor binding analogs and derivatives thereof, and the drug includes analogs and derivatives thereof. The vitamin receptor binding moiety is covalently linked to the bivalent linker, and the drug, or the analog or the derivative thereof, is covalently linked to the bivalent linker, wherein the bivalent linker (L) includes components such as spacer linkers, releasable linkers, and heteroatom linkers, and combinations thereof. Methods and pharmaceutical compositions for eliminating pathogenic cell populations using the drug delivery conjugate are also described.Type: ApplicationFiled: July 10, 2009Publication date: January 7, 2010Inventors: Iontcho R. Vlahov, Christopher P. Leamon, Matthew A. Parker, Stephen J. Howard, Hari Krishna Santhapuram, Apparao Satyam, Joseph Anand Reddy
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Publication number: 20090324499Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid of the formula H2NCHRCOOH, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.Type: ApplicationFiled: September 11, 2009Publication date: December 31, 2009Applicant: Endocyte, Inc.Inventors: Christopher P. LEAMON, Matthew A. PARKER
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Patent number: 7601332Abstract: The invention describes a vitamin receptor binding drug delivery conjugate, and preparations therefor. The drug delivery conjugate consists of a vitamin receptor binding moiety, a bivalent linker (L), and a drug. The vitamin receptor binding moiety includes vitamins, and vitamin receptor binding analogs and derivatives thereof, and the drug includes analogs and derivatives thereof. The vitamin receptor binding moiety is covalently linked to the bivalent linker, and the drug, or the analog or the derivative thereof, is covalently linked to the bivalent linker, wherein the bivalent linker (L) includes components such as spacer linkers, releasable linkers, and heteroatom linkers, and combinations thereof. Methods and pharmaceutical compositions for eliminating pathogenic cell populations using the drug delivery conjugate are also described.Type: GrantFiled: January 27, 2004Date of Patent: October 13, 2009Assignee: Endocyte, Inc.Inventors: Iontcho R. Vlahov, Christopher P. Leamon, Matthew A. Parker, Stephen J. Howard, Hari Krishna Santhapuram, Apparao Satyam, Joseph Anand Reddy
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Publication number: 20080228181Abstract: Methods are disclosed for delivering energy to a body of a human or animal during a treatment procedure using an electrosurgical generator, a pre-set overall procedure time being defined for the treatment procedure, a ramp time being defined for a parameter to reach a pre-set threshold during the treatment procedure, the method comprising: measuring the parameter over time; and if the parameter has not substantially reached the pre-set threshold by the ramp time, setting a procedure extension time responsive to the time difference between the ramp time and the time at which the pre-set threshold was reached, and extending the overall procedure time by the procedure extension time.Type: ApplicationFiled: February 25, 2008Publication date: September 18, 2008Applicant: Baylis Medical CompanyInventors: Neil GODARA, Taylor Hillier, Matthew Parker, Hua Xin Lo, Jason Woo
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Publication number: 20070031334Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid of the formula H2NCHRCOOH, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.Type: ApplicationFiled: October 11, 2006Publication date: February 8, 2007Inventors: Christopher Leamon, Matthew Parker