Abstract: In one instance, an attachment device for use in attaching a hook-and-loop patch to Modular Lightweight Load-carrying Equipment (MOLLE) includes a backing member having a central stem and a first cap and a second cap portion. The front side of the device has a hook or loop material applied to it. The first cap has a first wing and second wing. The second cap has a third wing and fourth wing. The backing material is flexible enough to allow the first cap or second cap to be compressed to go through a loop on a MOLLE and then released causing it to return to its original position. In this way, it is attached to a loop on the MOLLE and may then receive a coordinated hook or loop material on the back of a patch. Other embodiments are presented.

Abstract: An interchangeable electro-mechanical lock core for use with a lock device having a locked state and an unlocked state is disclosed. The interchangeable electromechanical lock core may include a moveable plug having a first position relative to a lock core body which corresponds to the lock device being in the locked state and a second position relative to a lock core body which corresponds to the lock device being in the unlocked state.

Abstract: Object picking optimization is disclosed, including: receiving an image of a target object; inputting the image in a machine learning model that is configured to output a pick probability heat map corresponding to the target object; selecting a pick location on the target object based at least in part on the pick probability heat map corresponding to the target object; and causing a diverting mechanism to perform a pick operation on the target object based at least in part on the pick location.

Abstract: Pick quality determination is disclosed, including: using a pressure meter to sense a pressure associated with an airflow through a gripper mechanism of a diverting mechanism over time during a pick operation on a target object; storing the sensed pressure associated with the airflow through the gripper mechanism over time as a pressure sequence associated with the pick operation on the target object; and correlating the pressure sequence with representative pressure sequences associated with corresponding pick quality types to determine whether the pick operation on the target object was successful or not.

Abstract: The present disclosure relates to cap analogs, which can result in high levels of capping efficiency and transcription and improved translation efficiencies. The present disclosure also relates to methods useful for preparing cap analogs and using mRNA species containing such analogs, as well as kits containing the novel cap analogs.

Abstract: The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them. In some aspects, the disclosure provides mRNA wherein the uracil content has been modified and which may be particularly effective for use in therapeutic compositions, because they may benefit from both high expression levels and limited induction of the innate immune response. In some aspects, the disclosure provides methods for the production of pharmaceutical compositions including mRNA without reverse phase chromatography.

Abstract: The present invention is directed to a small push-type lawn mower that can be converted into a riding mower. The mower includes a platform at the rear of the mower deck, and its handle assembly that can be pivoted forward making room for a user to step onto the platform. The handle assembly includes controls that drive electric motors that power the rear wheels allowing the user to ride the mower. The handle assembly can be pivoted rearwardly so that the user can access and grab the handle assembly and push the mower as is well known.

Abstract: The disclosure provides polynucleotides encoding a polypeptide including a morpholino linker. In some embodiments, the polynucleotides of the invention have increased stability compared to wild-type polynucleotides.

Abstract: A small push-type lawn mower that can be converted into a stand-on riding mower. The mower includes a platform at the rear of the mower deck, and a handle assembly that can be pivoted forwardly making room for a user to step onto the platform. The handle assembly includes controls that drive electric motors that power the rear wheels allowing the user to ride the mower. The handle assembly can be pivoted rearwardly so that the user can access and grab the handle assembly and push the mower while walking behind.

Abstract: Introduced here is a wafer separator configured to carry a semiconductor wafer with improved efficiency, protection, and reduced costs when utilized in the handling, transport, or storage of semiconductor components. The wafer separator may include a circular ring having an outer edge defining a periphery of the circular ring. The circular ring may include an inner edge defining a central opening of the circular ring. The wafer separator may include a first-right angled recess for receiving a semiconductor wafer that extends downward from a top surface of the circular ring. The wafer separator may also include a second right-angled recess for maintaining a gap beneath the semiconductor wafer when the semiconductor wafer is set within the first right-angled recess. In some embodiments, the wafer separator also includes interlock components for connecting the wafer separator to adjacent wafer separators.

Abstract: Introduced here are carrier assemblies designed to address the limitations of conventional carrier trays. A carrier assembly can comprise a primary injection-molded component having a deck area for receiving semiconductor components and a secondary injection-molded component that is secured to the deck area of the primary injection-molded component. For example, the secondary injection-molded component may be overmolded on the deck area of the primary injection-molded component. The secondary injection-molded component may have a tacky upper surface that facilitates securement of the semiconductor components to the primary injection-molded component.

Abstract: A vacuum tube assembly for removing material is disclosed, including: a vacuum generator configured to generate a vacuum airflow; one or more tubes coupled to the vacuum generator and configured to channel the vacuum airflow; and an actuation mechanism coupled to the one or more tubes, wherein the actuation mechanism is configured to actuate at least one tube from a first position relative to a material stream to a second position relative to the material stream, wherein the first position is farther from the material stream than the second position.

Abstract: The disclosure provides polynucleotides encoding a polypeptide including a morpholino linker. In some embodiments, the polynucleotides of the invention have increased stability compared to wild-type polynucleotides.

Abstract: The present application discloses methods for synthetic production and cell-free synthesis of DNA vectors, particularly closed-ended linear DNA vectors having one or more gaps (e.g., nicked ceDNA vectors, “neDNA”) and adenoassociated-virus (AAV) vector which is single strand DNA having linear and continuous structure, for delivery and expression of a transgene in the host cell. The present invention also relates to an in vitro process for production of closed-ended DNA vectors, corresponding DNA vector products produced by the methods and uses thereof, and oligonucleotides and kits useful in the process of the present invention.

Abstract: The present application discloses methods for synthetic production and cell-free synthesis of single stranded adeno-associated virus (AAV) vectors, for delivery and expression of a transgene in host cells. The present invention also relates to an in vitro process for production of closed-ended DNA vectors and corresponding single stranded AAV DNA vector products synthesized from the closed-ended DNA vectors having nicks.

Abstract: Provided herein are methods and constructs related to minimizing immune responses using modified dexamethasone compounds when administering a desired transgene in a cell achieved by delivery of the transgene with one or more doses of a ceDNA construct.

Abstract: A material picker assembly is disclosed, including: a connector configured to be attached to an actuator device; and a plurality of picker mechanisms, wherein each picker mechanism includes a suspension element that is configured to absorb impact on the picker mechanism by one or more objects.

Abstract: Introduced here are carrier assemblies that include a rigid tray having a deck area with a patterned surface of cavities for receiving semiconductor components. The cavities can be designed to accommodate semiconductor components of different form factors (e.g., having different shapes, sizes, etc.). Moreover, an adhesive film can be affixed to the deck area to ensure that the semiconductor components are securely held against the top surface of the rigid tray. In some instances the adhesive film substantially conforms to the deck area, while in other instances the adhesive film extends across the opening of each cavity located in the deck area. Semiconductor component(s) can be secured to the carrier assembly based on the adhesiveness provided by the adhesive film, mechanical force provided the cavities, electrostatic force provided by the cavities, or any combination thereof.

Abstract: In one instance, an attachment device for use in attaching a hook-and-loop patch to Modular Lightweight Load-carrying Equipment (MOLLE) includes a backing member having a central stem and a first cap and a second cap portion. The front side of the device has a hook or loop material applied to it. The first cap has a first wing and second wing. The second cap has a third wing and fourth wing. The backing material is flexible enough to allow the first cap or second cap to be compressed to go through a loop on a MOLLE and then released causing it to return to its original position. In this way, it is attached to a loop on the MOLLE and may then receive a coordinated hook or loop material on the back of a patch. Other embodiments are presented.

Abstract: A chuck including a chuck body that supports a plurality of jaws. An outer sleeve is axially fixed with respect to the chuck body. A nut is coupled to the outer sleeve, and the nut is movable axially and radially relative to the chuck body. The nut interacts with the jaws such that when the outer sleeve rotates, the nut moves axially and radially relative to the body.