Abstract: A method for in vitro diagnosing asphyxia and disorders related thereto, a method of in vitro estimating duration of hypoxia in a patient subjected to asphyxia, and a method for in vitro monitoring of normoxic, hypoxic and hyperoxic conditions and/or normobaric and hyperbaric oxygen therapy, includes quantitatively detecting in a biological sample of a patient a plurality of asphyxia specific endogenous compounds which are selected from the group consisting of biogenic amines; carnitine-derived compounds; amino acids; bile acids; carboxylic acids; eicosanoids; lipids; precursors of cholesterol, cholesterol metabolites; prostanoids; and sugars.

Abstract: Disclosed is a moisture curable adhesive composition comprising at least one silane-modified polymer, a filler comprising a surface modified fumed silica and one of a surface modified cristobalite and a silica; and optionally, at least one of an aminosilane adhesion promotor, an organotin catalyst, a dehydration shelf life enhancer, a light stabilizer, titanium dioxide, a rheology modifier, and mixtures thereof. The adhesive composition finds special use in bonding metal substrates to each other with significantly higher bond strength than that provided by silane-modified polymer adhesives alone.

Abstract: A moisture-curing two-component composition consisting of a component A containing at least one polyoxyalkylene, polyolefin and/or polyacrylate prepolymer having at least one hydrolysable silane group and at least one solid inert additive selected from hydrocarbons, polyesters or polyamides, a component B containing at least one crosslinking compound for the prepolymers, and auxiliary substances and additives in one or both components, the component A and the two-component composition each having hot-melt adhesive properties.

Abstract: A method for in vitro diagnosing asphyxia and disorders related thereto, a method of in vitro estimating duration of hypoxia in a patient subjected to asphyxia, and a method for in vitro monitoring of normoxic, hypoxic and hyperoxic conditions and/or normobaric and hyperbaric oxygen therapy, includes quantitatively detecting in a biological sample of a patient a plurality of asphyxia specific endogenous compounds which are selected from the group consisting of biogenic amines; carnitine-derived compounds; amino acids; bile acids; carboxylic acids; eicosanoids; lipids; precursors of cholesterol, cholesterol metabolites; prostanoids; and sugars.

Abstract: A method for in vitro diagnosing asphyxia and disorders related thereto, a method of in vitro estimating duration of hypoxia in a patient subjected to asphyxia, and a method for in vitro monitoring of normoxic, hypoxic and hyperoxic conditions and/or normobaric and hyperbaric oxygen therapy, includes quantitatively detecting in a biological sample of a patient a plurality of asphyxia specific endogenous compounds which are selected from the group consisting of biogenic amines; carnitine-derived compounds; amino acids; bile acids; carboxylic acids; eicosanoids; lipids; precursors of cholesterol, cholesterol metabolites; prostanoids; and sugars.

Abstract: The invention aims to improve temperature resistance for a curable composition based on a silyl-terminated polymer. This is achieved by using a combination of at least two phenolic compounds, of which one is free of thioether groups, while the other contains at least one thioether group in at least one alkyl side chain. The invention further relates to the use of the curable composition as an adhesive, sealant and/or coating substance and to the use of the combination of phenolic compounds to increase the temperature stability in curable compositions.

Abstract: A compound having formula (I) where R is C9-C11 alkyl, C9-C11 alkenyl, C17 alkyl or C17 alkenyl.

Abstract: Moisture-hardening 1-component or 2-component composition that contains at least one prepolymer with at least one hydrolysable silane group, chosen from silane-modified polyoxyalkenes, polyolefins, poly(meth)acrylates, polyurethanes, polyamides or polysiloxanes, a Sn-based catalyst and optionally adjuvants and additives, wherein the catalyst is selected from tetramethyl-stannoxy dicarboxylates.

Abstract: A moisture-curing two-component composition consisting of a component A containing at least one polyoxyalkylene, polyolefin and/or polyacrylate prepolymer having at least one hydrolysable silane group and at least one solid inert additive selected from hydrocarbons, polyesters or polyamides, a component B containing at least one crosslinking compound for the prepolymers, and auxiliary substances and additives in one or both components, the component A and the two-component composition each having hot-melt adhesive properties.

Abstract: The invention relates to curable compositions comprising a) at least one organic polymer selected from polyethers and polyacrylic acid esters, wherein the organic polymer has at least one defined, cross-linkable end group having at least one C1-C8-alkoxy- or C1-C8-acyloxy radical, b) at least one poly(dialkylsiloxane) having at least one defined, cross-linkable end group having at least one vinyl radical and likewise at least one C1-C8-alkoxy- or C1-C8-acyloxy radical and c) at least one flame-retarding additive selected from red phosphorus, organic phosphor compounds, ammonia polyphosphate, metal hydroxides, expandable graphite, zinc borate and melamine salts, to the use of such compositions as adhesive, sealing or coating material, in particular for providing a substrate having a flame-retardant, elastic coating, to a coating thus obtained and to the use of at least one poly(dialkylsiloxane) b) to improve the fire properties of a curable composition comprising at least one organic polymer a).

Abstract: A one-component moisture-curing adhesive containing at least one flowable polyoxyalkylene or polyacrylate prepolymer with at least one hydrolyzable silane group, at least one inert additive solid at room temperature selected from hydrocarbon resins, polyesters or polyamides with a softening point of 40 to 150° C., together with auxiliary substances and additives.

Abstract: The invention relates to curable compositions comprising a) at least one organic polymer selected from polyethers and polyacrylic acid esters, wherein the organic polymer has at least one defined, cross-linkable end group having at least one C1-C8-alkoxy- or C1-C8-acyloxy radical, b) at least one poly(dialkylsiloxane) having at least one defined, cross-linkable end group having at least one vinyl radical and likewise at least one C1-C8-alkoxy- or C1-C8-acyloxy radical and c) at least one flame-retarding additive selected from red phosphorus, organic phosphor compounds, ammonia polyphosphate, metal hydroxides, expandable graphite, zinc borate and melamine salts, to the use of such compositions as adhesive, sealing or coating material, in particular for providing a substrate having a flame-retardant, elastic coating, to a coating thus obtained and to the use of at least one poly(dialkylsiloxane) b) to improve the fire properties of a curable composition comprising at least one organic polymer a).

Abstract: Apparatus for measuring blood parameters such as chromophore, for example haemoglobin, concentration and blood flow detects light scattered from tissue surface (20) with a multispectral detector (24) that is sensitive to light across a range of different wavelengths. Algorithms are described that demonstrate extraction of chromophore information from scattered light occupying two, red and green or blue, or three bands of the visible spectrum. Simultaneous extraction of blood flow information from scattered laser light occupying either the same or a distinct spectral band is also described.

Abstract: The present invention relates to the use of endogenous reference metabolites and a method for normalization of intensity data corresponding to amounts and/or concentrations of selected target metabolites in a biological sample of a mammalian subject, wherein said intensity data are obtained by a metabolomics analysis method with one or a plurality of endogenous reference metabolites, comprising carrying out at least one in vitro metabolomics analysis method of said selected target metabolites in said biological sample, simultaneously carrying out in the same sample a quantitative analysis of one or a plurality of endogenous reference metabolites or derivatives thereof, wherein said endogenous reference metabolites are such compounds in the biological sample which are present in the subject at an essentially constant level; and wherein said endogenous reference metabolites or derivatives thereof have a molecular mass less than 1500 Da.

Abstract: The present invention relates to a reliable and statistically significant method for predicting the likelihood of an onset of an inflammation associated organ failure from a biological sample of a mammalian subject in vitro, by means of a subject's quantitative metabolomics profile comprising a plurality of endogenous metabolites, and comparing it with a quantitative reference metabolomics profile of a plurality of endogenous organ failure predictive target metabolites in order to predict whether the subject is likely or unlikely to develop an organ failure. Furthermore, the invention relates to the usefulness of endogenous organ failure predictive target metabolites in such a method.

Abstract: A method for in vitro diagnosing asphyxia and disorders related thereto, a method of in vitro estimating duration of hypoxia in a patient subjected to asphyxia, and a method for in vitro monitoring of normoxic, hypoxic and hyperoxic conditions and/or normobaric and hyperbaric oxygen therapy, includes quantitatively detecting in a biological sample of a patient a plurality of asphyxia specific endogenous compounds which are selected from the group consisting of biogenic amines; carnitine-derived compounds; amino acids; bile acids; carboxylic acids; eicosanoids; lipids; precursors of cholesterol, cholesterol metabolites; prostanoids; and sugars.

Abstract: The present invention relates to a method and kit for in vitro diagnosing a complex disease such as cancer, in particular, acute myeloid leukemia (AML), colon cancer, kidney cancer, prostate cancer; transient ischemic attack (TIA), ischemia, in particular stroke, hypoxia, hypoxic-ischemic encephalopathy, perinatal brain damage, hypoxic-ischemic encephalopathy of neotatals asphyxia; demyelinating disease, in particular, white-matter disease, periventricular leukoencephalopathy, multiple sclerosis, Alzheimer and Parkinson's disease; in a biological sample. For the diagnosis, use is made of measuring at least two different species of biomolecules and classifying the results by means of suitable classifier algorithms and other statistical procedures. With the present invention, a significant improvement of the reliability of e.g. expression profiles alone, are achieved.

Abstract: A single- or multi-component adhesive/sealant compositions containing at least one silane-terminated prepolymer, wherein the adhesive/sealant compositions are free of organic heavy metal catalysts, and the silane-terminated prepolymers comprise terminal groups that are selected from among methyldialkoxysilylpropyl, trialkoxysilylpropyl, methyldialkoxysilylmethyl, trialkoxysilylmethyl, or mixtures thereof. In the two-component embodiment, the adhesive/sealant compositions consist of a component A, containing at least one silane-terminated prepolymer of the aforementioned type, and a component B, containing water and thickener. Said adhesive/sealant compositions are used to elastically bond two or more identical and/or dissimilar substrates, in particular in the production of photovoltaic modules, and in the mounting of photovoltaic modules onto roof surfaces and other surfaces.

Abstract: A one-component moisture-curing adhesive containing at least one flowable polyoxyalkylene or polyacrylate prepolymer with at least one hydrolyzable silane group, at least one inert additive solid at room temperature selected from hydrocarbon resins, polyesters or polyamides with a softening point of 40 to 150° C., together with auxiliary substances and additives.

Abstract: Monocomponent water-hardening adhesive/sealant compositions comprising mixtures of at least one silane-functional polyoxyalkylene prepolymer and at least one silane-functional polyolefin are described. These compositions may optionally comprise other nonpolar plasticizers, as well as catalysts, fillers, and adhesives. Such adhesive/sealant compositions exhibit outstanding adhesion to plastic substrates and to painted surfaces, whereby the adhesion is maintained even after storage in wet conditions.