Patents by Inventor Matthias Schnell

Matthias Schnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7074413
    Abstract: Live, attenuated recombinant rabies virus vaccines are generated using reverse genetics to combine the antigenic determinants that render the rabies virus non-pathogenic with the determinants that are responsible for the elicitation of an effective anti-rabies immune response. These vaccines do not affect the antigenic, and therefore the immunogenic, properties of the virus. The present invention further relates to recombinant rabies virus vaccines that express a pro-apoptotic protein, such as cytochrome c, to increase the capacity to induce apoptosis, thereby enhancing the protective immunity against rabies. This new generation of live rabies virus vaccines represents a safe and effective approach to the eradication of rabies in wildlife, and subsequently humans and livestock.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: July 11, 2006
    Assignee: Thomas Jefferson University
    Inventors: Bernhard Dietzschold, D. Craig Hooper, Matthias Schnell, Charles E. Rupprecht
  • Publication number: 20020131981
    Abstract: Live, attenuated recombinant rabies virus vaccines are generated using reverse genetics to combine the antigenic determinants that render the rabies virus non-pathogenic with the determinants that are responsible for the elicitation of an effective anti-rabies immune response. These vaccines do not affect the antigenic, and therefore the immunogenic, properties of the virus. The present invention further relates to recombinant rabies virus vaccines that express a pro-apoptotic protein, such as cytochrome c, to increase the capacity to induce apoptosis, thereby enhancing the protective immunity against rabies. This new generation of live rabies virus vaccines represents a safe and effective approach to the eradication of rabies in wildlife, and subsequently humans and livestock.
    Type: Application
    Filed: March 23, 2001
    Publication date: September 19, 2002
    Inventors: Bernhard Dietzschold, D. Craig Hooper, Matthias Schnell
  • Patent number: 6239372
    Abstract: An electrical connection in which a flexible, elastic conductor track carrier is affixed by a connecting end to an electrical component and embedded in potting compound. To prevent breakage at the fastening point at the transition from the potting compound to the outside, the conductor track carrier is reinforced with additional layers of insulating material.
    Type: Grant
    Filed: May 27, 1998
    Date of Patent: May 29, 2001
    Assignees: Robert Bosch GmbH
    Inventors: Bernhard Gartner, Matthias Schnell, Joerg Wolke, Peter Schaefer, Hans-Erich Steinmann, Guenter Trogisch