Patents by Inventor Mattias Myrman
Mattias Myrman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080184998Abstract: An improved foil-cutting device is disclosed for opening a foil protecting a pre-metered dose of medication power carried by dose carrier to be used in an inhaler device. The dose carrier with the medication powder is covered by a seal, e.g. metallic or plastic foil. The foil-cutter device of the present invention provides a knife device tool for simultaneous access of a selected sealed dose of medication powder during an inhalation process using a dry powder inhaler (DPI).Type: ApplicationFiled: December 12, 2005Publication date: August 7, 2008Applicant: MEDERIO AGInventors: Mattias Myrman, Mats Eriksson
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Patent number: 7278426Abstract: A method and a device for making a metered dry powder medication dose, enclosed in a dose container, accessible for inhalation with a minimum of exposure to ambient atmosphere.Type: GrantFiled: June 6, 2005Date of Patent: October 9, 2007Assignee: Mederio AGInventor: Mattias Myrman
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Publication number: 20070110678Abstract: A method for administration and preparation of pharmaceutical dry powder doses are disclosed. The metered dry powder doses are formed from a finely divided dry powder of an selected anticholinergic agent to be used in a dry powder inhaler device. The metered dry powder medicinal dose is arranged as a medicinally effective quantity of the selected medicament onto a dose bed and moisture-tight sealed by using a high barrier seal, for introduction into an inhaler device provided with an Air-razor device for obtaining a fine particle fraction, FPF, of at least 30-50% of delivered powder mass when suction through the inhaler is applied, whereby the dose is delivered to and deposited in the lung of the user during a single inhalation effort.Type: ApplicationFiled: June 8, 2006Publication date: May 17, 2007Inventors: Bernd Zierenberg, Holger Memmesheimer, Christine Lunkenheimer, Sven Calander, Alf Niemi, Thomas Nilsson, Mattias Myrman
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Publication number: 20070104655Abstract: A medical product suitable for storing and delivering a pre-metered dose of tiotropium, devices containing the same, and methods of using the same.Type: ApplicationFiled: June 8, 2006Publication date: May 10, 2007Inventors: Bernd Zierenberg, Holger Memmesheimer, Christine Lunkenheimer, Sven Calander, Alf Niemi, Thomas Nilsson, Mattias Myrman
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Publication number: 20070101991Abstract: A method based on an Air-razor tool is disclosed thereby providing improved release and dispersal into air of a dose of medication powder. When air is sucked through a suction tube, particles of a powder dose, made available to the suction tube, are gradually released and dispersed into a stream of air entering the suction tube. The gradual release and dispersal is produced by a relative motion introduced between the suction tube and the dose. The high velocity air going into the suction tube inlet provides plenty of shearing stress and inertia energy as the flowing air hits the leading point of the dose. This powder Air-razor method, created by the shearing stress and inertia of the air stream, is so powerful that the particles of the powder adjacent to the inlet of the moving suction tube are released and subsequently entrained in the air stream going through the suction tube.Type: ApplicationFiled: November 8, 2005Publication date: May 10, 2007Applicant: MEDERIO AGInventors: Mattias Myrman, Mats Eriksson
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Publication number: 20070020198Abstract: The invention discloses a medical product that may be used in a treatment of respiratory disorders.Type: ApplicationFiled: June 8, 2006Publication date: January 25, 2007Inventors: Thomas Nilsson, Mattias Myrman, Sven Calander, Alf Niemi, Bernd Zierenberg, Holger Memmesheimer, Christine Lunkenheimer
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Publication number: 20060257327Abstract: The invention discloses a medical product for use in a treatment of respiratory disorders, and comprises a metered dose of a tiotropium dry powder formulation, directly loaded and sealed into a container made to act as a dry high barrier seal to prevent the capture and ingress of moisture into the tiotropium powder. The dose of tiotropium is further adapted for inhalation and the container is so tight that the efficacy of the dose when delivered is unaffected by moisture. In a further aspect of the invention a type of inhaler is illustrated, which may accept at least one sealed, moisture-tight container of a dose of tiotropium, to deliver the dose with a consistent fine particle dose, over the expected shelf life of the product.Type: ApplicationFiled: June 8, 2006Publication date: November 16, 2006Inventors: Bernd Zierenberg, Holger Memmesheimer, Christine Lunkenheimer, Sven Calander, Alf Niemi, Thomas Nilsson, Mattias Myrman
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Publication number: 20060239933Abstract: A medical product is disclosed. The medical product contains an accurately metered dose of at least one GLP medicament intended for pulmonary inhalation put into a moisture-tight, high barrier seal container. The medical product optionally also contains a dose of insulin. The container is adapted for application into a dry powder inhaler. The dose loaded in the container is intended for a prolonged delivery by inhalation to the deep lung where the active ingredients are absorbed into the system. Optionally the medical product also may comprise at least one biologically acceptable excipient.Type: ApplicationFiled: November 15, 2005Publication date: October 26, 2006Applicant: MEDERIO AGInventors: Thomas Nilsson, Sven Calander, Alf Niemi, Claes Friberg, Lars Kax, Mattias Myrman
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Publication number: 20060120969Abstract: A medical product containing an accurately metered dose of a GLP-1 medicament intended for pulmonary inhalation put into a moisture-tight, high barrier seal container. The medical product optionally also contains a dose of insulin. The container is preferably adapted for application into a dry powder inhaler. The dose loaded in the container is intended for a prolonged delivery by inhalation to the deep lung where the active ingredients are absorbed into the system. Optionally the medical product also may comprise at least one biologically acceptable excipient.Type: ApplicationFiled: February 4, 2005Publication date: June 8, 2006Applicant: Microdrug AGInventors: Thomas Nilsson, Sven Calander, Alf Niemi, Claes Friberg, Lars Kax, Mattias Myrman
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Publication number: 20060067911Abstract: The invention discloses a metered medication dose of a dry powder protein medicament, particularly a peptide medicament, intended for inhalation by use of an adapted dry powder inhaler. An active peptide agent is presented in a pure, natural, crystalline, micronized, dry powder form. A dose comprises at least one such peptide powder and may optionally comprise at least one biologically acceptable excipient in dry powder form. The dose does not include any substances that are intended to change one, some or all properties of the at least one peptide with an object of improving the stability or systemic absorption of the active peptide or peptides deposited.Type: ApplicationFiled: April 22, 2005Publication date: March 30, 2006Applicant: MEDERIO AGInventors: Thomas Nilsson, Claes Friberg, Lars Kax, Alf Niemi, Mattias Myrman, Sven Calander
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Publication number: 20060021616Abstract: A dry powder inhaler device (DPI) is disclosed. When a user activates the inhaler, the DPI is capable of delivering a dry powder dose directly from a medicament container, loaded into the DPI. A method is also disclosed for delivering a dry powder medicament dose directly from a container to a user of a DPI, whereby a sealing foil of the container is being slit open concurrently with aerosolizing and entraining of the powder in the dose into the inhaled air.Type: ApplicationFiled: June 6, 2005Publication date: February 2, 2006Applicant: MEDERIO AGInventor: Mattias Myrman
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Publication number: 20060000473Abstract: A method and a device for making a metered dry powder medication dose, enclosed in a dose container, accessible for inhalation with a minimum of exposure to ambient atmosphere.Type: ApplicationFiled: June 6, 2005Publication date: January 5, 2006Applicant: MEDERIO AGInventor: Mattias Myrman
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Publication number: 20050279356Abstract: A medicament container for carrying a metered, finely divided, dry powder medication dose is disclosed. The medicament container, which is intended for administration by a dry powder inhaler device, constitutes a pod presents a bottom surface acting as a dose bed adapted for receiving a metered medication dose. The metered dose, carried by the pod, is protected from foreign matter, particularly moisture, after a sealing of the pod with a high barrier seal foil, which transforms the pod into a high barrier container. Furthermore the pod is formed such that the pod sealing foil can be slit open from a point of penetration at a first pod end to a point of exit at a second pod end by a cutter set in motion relative to the pod.Type: ApplicationFiled: July 26, 2004Publication date: December 22, 2005Applicant: Microdrug AGInventors: Claes Friberg, Lars Kax, Mattias Myrman
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Publication number: 20050121032Abstract: The invention discloses a dry powder inhaler for use in a treatment of respiratory disorders.Type: ApplicationFiled: September 3, 2004Publication date: June 9, 2005Applicant: Microdrug AGInventors: Thomas Nilsson, Mattias Myrman, Sven Calander, Alf Niemi
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Publication number: 20050121027Abstract: A medical product suitable for storing and delivering a pre-metered dose of tiotropium, devices containing the same, and methods of using the same.Type: ApplicationFiled: April 29, 2004Publication date: June 9, 2005Applicant: Microdrug AGInventors: Thomas Nilsson, Mattias Myrman, Sven Calander, Alf Niemi
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Publication number: 20050124644Abstract: The invention discloses a medical product for use in a treatment of respiratory disorders, and comprises a metered dose of a tiotropium dry powder formulation, directly loaded and sealed into a container made to act as a dry high barrier seal to prevent the capture and ingress of moisture into the tiotropium powder. The dose of tiotropium is further adapted for inhalation and the container is so tight that the efficacy of the dose when delivered is unaffected by moisture. In a further aspect of the invention a type of inhaler is illustrated, which may accept at least one sealed, moisture-tight container of a dose of tiotropium, to deliver the dose with a consistent fine particle dose, over the expected shelf life of the product.Type: ApplicationFiled: December 8, 2003Publication date: June 9, 2005Inventors: Thomas Nilsson, Mattias Myrman, Sven Calander, Alf Niemi
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Publication number: 20050121026Abstract: A method for administration and preparation of pharmaceutical dry powder doses are disclosed. The metered dry powder doses are formed from a finely divided dry powder of an selected anticholinergic agent to be used in a dry powder inhaler device. The metered dry powder medicinal dose is arranged as a medicinally effective quantity of the selected medicament onto a dose bed and moisture-tight sealed by using a high barrier seal, for introduction into an inhaler device provided with an Air-razor device for obtaining a fine particle fraction, FPF, of at least 30-50% of delivered powder mass when suction through the inhaler is applied, whereby the dose is delivered to and deposited in the lung of the user during a single inhalation effort.Type: ApplicationFiled: December 8, 2003Publication date: June 9, 2005Inventors: Thomas Nilsson, Mattias Myrman, Sven Calander, Alf Niemi
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Publication number: 20050123486Abstract: The invention discloses a medical product that may be used in a treatment of respiratory disorders.Type: ApplicationFiled: August 19, 2004Publication date: June 9, 2005Applicant: Microdrug AGInventors: Thomas Nilsson, Mattias Myrman, Sven Calander, Alf Niemi
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Patent number: 6892727Abstract: A device and an arrangement are disclosed, which create a powder Air-razor, which into an inhalation air volume de-aggregates and disperses a finely divided medication powder. The powder is generally loaded onto a dosing member intended for use with an inhaler. By sucking air through a mouthpiece connected to a nozzle, particles of the load of powder are gradually de-aggregated, dispersed and continuously released into the sucked air during a defined interval. The gradual de-aggregation and dispersal of the medication powder is generated by a relative motion introduced between the nozzle and the dosing member. The powder is generally loaded onto a larger area than the area of the air nozzle inlet. The nozzle may be positioned outside the dose area until an air stream has begun to flow into the nozzle by suction of air in an inhaling operation.Type: GrantFiled: April 30, 2002Date of Patent: May 17, 2005Assignee: Mederio AGInventor: Mattias Myrman
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Patent number: 6881398Abstract: A therapeutic dry powder preparation and a method of administering such a preparation are disclosed for effectively de-aggregating and dispersing into air a dose of medication powder in an administration the dose to a user. The present dry powder preparation and method do not require other sources of energy besides the power of an inhalation effort by a user to produce a very high degree of de-aggregation and efficient dispersal into air of the dry powder medication dose. Utilizing an effort of sucking air through a nozzle, the particles of the therapeutic powder dose, made available to the nozzle, are gradually de-aggregated and dispersed into a stream of air entering the nozzle.Type: GrantFiled: April 30, 2002Date of Patent: April 19, 2005Assignee: Microdrug AGInventors: Mattias Myrman, Per-Gunnar Nilsson