Abstract: A make-up product (1) comprising a transfer or writing surface (2), at least one part (3) of said transfer surface (2) having a surface finish featuring parallel grooves (S), so as to determine a plurality of relief elements (P), each with at least a first face (A) and a second face (B) facing the exposed surface of the said part (3) of the transfer surface (2), each first face (A) facing in an essentially opposite direction to each second face (B), at least some of the first faces (A) having cavities (20) or reliefs arranged so as to form a first FIG. 4), at least some of the second faces (B) having cavities (20) or reliefs so as to form a second FIG. 5) so that, when tilting the make-up product (1) so that mostly the first faces are visible (A), the first FIG. 4) is visible, while when tilting the make-up product (1) so that mostly the second faces are visible (B), the second figure is visible (5).

Abstract: The present invention relates to a process for the preparation of Fulvestrant which includes recovering the by-products deriving from the oxidation of the corresponding sulfide and then subjecting the by-products to a reduction reaction in the presence of specific reducing agents.

Abstract: A method for forming a stick for lips includes positioning a mould (2) made of an elastic material, such as silicone, on a first support (11), the said mould comprising a casting cavity (4) endowed with an opening (5). The method further includes centring a cup (3) in the casting cavity (4) opening (5), pouring a melted cosmetic product through the cup (3) and into the casting cavity (4), waiting for the solidification of the melted cosmetic product in the casting cavity (4) so as to form the stick, and extracting the stick (7) from the cavity by gripping the cup (3).

Abstract: A process for the preparation of fulvestrant 3-boronic acid and intermediates useful for the preparation of fulvestrant 3-boronic acid according to the process are described. Fulvestrant 3-boronic acid is obtained with high purity.

Abstract: A make-up product (1) with at least one visible surface (2) on which at least a plurality of basic three-dimensional elements (B) and a plurality of modified three-dimensional elements (M) are obtained, the basic three-dimensional elements (B) being arranged on the surface in a primary pattern (P), in primary rows (P1, P2, . . . ) and mutually side by side, so as to be positioned one after another each on each primary row (P1, P2, . . . ), the modified three-dimensional elements (M) being arranged on the surface in a secondary pattern (S), in secondary rows (S1, S2, . . . ) and mutually side by side, so as to be positioned one after another on each secondary row (S1, S2, . . . ), the secondary pattern (S) replacing the primary pattern (P)—and therefore interrupting it—in some parts of the surface (S) so as to form a figure (F) which is visible when lit from predefined angles.

Abstract: The present invention discloses a method for the purification of cysteamine or a salt thereof from polysulfuric impurities, in particular from cystamine, by treatment with dithiothreitol.

Abstract: The present invention relates to a process for the synthesis of cysteamine or a salt thereof.

Abstract: A process for the synthesis of Sofosbuvir is provided comprising the steps of selectively mono-deacetylating a compound of formula (V) enzymatically using a resin supported lipase B derived from Candida Antarctica to obtain a compound formula (IV), then converting the compound of formula (IV) to a compound of formula (II) by reacting the compound of formula (IV) with a compound of formula (III), and then converting the compound of formula (II) to Sofosbuvir of formula (I) by deacetylation reaction.

Abstract: Processing device of a makeup product comprising: a first plate provided with first mutually adjacent channels with parallel axes, of semicircle section, and a second plate provided with second mutually adjacent channels with parallel axes, also of semicircle section, the first and the second channels being configured such that, when the first plate and the second plate are overlapped with their respective channels facing each other, each pair of first and second channels forms a tubular element with circular section; the device having guides configured to allow the movement of a plate relative to the other, in a direction parallel with respect to the axes of the channels; and at least one movement system of a plate relative to the other.

Abstract: The present invention relates to a process for the synthesis of cysteamine or a salt thereof.

Abstract: Sofosbuvir in crystalline Form ?, process for its production and use in pharmaceutical compositions.

Abstract: Sofosbuvir in crystalline Form ?, process for its production and use in pharmaceutical compositions.

Abstract: A process for the synthesis of Dapsone and intermediates thereof are described.

Abstract: The present invention relates to a process for the synthesis of Sofosbuvir.

Abstract: A process for the synthesis of Dapsone and intermediates thereof are described.

Abstract: Sofosbuvir in crystalline Form ?, process for its production and use in pharmaceutical compositions.

Abstract: Novel retinoic acid derivatives and a process for their preparation are described.

Abstract: The present invention relates to a new process for the synthesis of Colesevelam, which is used in therapy in cases of hypercholesterolemia due to low density lipoproteins. Said process comprises the reaction, in a basic environment, of polyallylamine with: i) at least one alkylating agent of formula X—(CH2)9—CH3 and at least one alkylating agent of formula Y—(CH2)6—N+ (CH3)3Z?, wherein X and Y are each independently a leaving group, and Z is a halogen; and ii) at least one crosslinking agent. The present invention also relates to the Colesevelam obtainable by the above process.

Abstract: A process for the preparation of Erlotinib is disclosed in which the compound of formula (II) Is reacted with the compound of formula (III) in the presence of trifluoroacetic acid and formamidine acetate, in an aprotic solvent, and the reaction product is subsequently treated with a source of hydrochloric acid in a suitable solvent to give Erlotinib hydrochloride.

Abstract: Novel retinoic acid derivatives and a process for their preparation are described.