Abstract: A manifold assembly for a peritoneal dialysis apparatus, comprises: a casing delimiting internally a first compartment and a second compartment; a yielding pump tube having a first end connected or connectable to the first compartment and a second end connected or connectable to the second compartment. The yielding pump tube extends outside the casing to be coupled to a peristaltic pump of a cycler of a peritoneal dialysis apparatus. A first pump port and a second pump port are placed on a first side of the casing and ports are placed on a second side of the casing, opposite the first side.

Abstract: A method for calibrating a peristaltic pump in a medical apparatus comprises: rotating the peristaltic pump of a predetermined rotation to pump a liquid from a fluid source from a first compartment into a second compartment of a manifold assembly, raising a level of the liquid in the second compartment and compressing air in an air buffer volume of the manifold assembly; measuring a pressure of air in the air buffer volume; calculating, from the measured pressure, a variation of liquid volume in the second compartment due to the rotation of the peristaltic pump; calculating, from the variation of liquid volume and the predetermined rotation, a stroke liquid volume of the peristaltic pump.

Abstract: A manifold assembly for a peritoneal dialysis apparatus, comprises: a casing delimiting internally a first compartment and a second compartment; a yielding pump tube having a first end connected or connectable to the first compartment and a second end connected or connectable to the second compartment. The yielding pump tubes extends outside the casing to be coupled to a peristaltic pump of a cycler of a peritoneal dialysis apparatus. The second compartment delimits expansion chambers configured to attenuate pressure pulsations from the peristaltic pump.

Abstract: A peritoneal dialysis (“PD”) system includes a housing; a PD fluid pump housed by the housing; a filter set including a filter housing and a hydrophilic filter membrane dividing an upstream chamber from a downstream chamber; a dual lumen patient line including a fresh PD fluid lumen in fluid communication with the upstream chamber and a used PD fluid lumen in fluid communication with the downstream chamber; a pressure sensor positioned and arranged to provide a pressure sensor output indicative of pressure in the downstream chamber of the filter housing; and a control unit configured to perform a pressure integrity test on the hydrophilic filter membrane by monitoring the pressure sensor output over a period of time, the pressure sensor output indicative of a negative pressure created in the downstream chamber by the PD fluid pump. A pressure drop test for evaluating the filter membrane is also disclosed.

Abstract: A peritoneal dialysis fluid circuit comprising a patient line, a delivery line configured to supply fresh dialysis fluid towards the patient line, a withdrawal line configured to withdraw spent dialysis fluid from the patient line, a first pump arranged on the delivery line and configured to supply fresh dialysis fluid towards the patient line, and a second pump arranged on the withdrawal line and configured to withdraw spent dialysis fluid from the patient line. The fluid circuit further comprises a control unit configured to perform a peritoneal dialysis procedure. The peritoneal dialysis procedure comprises commanding activation of the first pump at a first flow rate, and activation of the second pump at a second flow rate different from the first flow rate: the first pump and the second pump are active simultaneously to provide the first flow rate and the second flow rate.

Abstract: An apparatus for an extracorporeal treatment of blood has a supply line, a waste line, and an ultrafilter inserted in the supply line. An air inlet line is connected to a first chamber of the ultrafilter. A pressure sensor is configured for detecting pressure in the waste line or a second chamber of the ultrafilter. A controller is configured to perform an integrity test procedure for detecting when an ultrafilter membrane of the ultrafilter has multiple or single fiber breaks. A method of testing the ultrafilter is also disclosed.

Abstract: An apparatus for extracorporeal blood treatment comprising a filtration unit, a blood circuit comprising a blood with-line and a blood return line, and a fluid circuit. The fluid circuit comprises at least one or more water inlet ducts for receiving water, a dialysis preparation assembly comprising one or more concentrated sources housing a respective concentrate solution and configured to prepare a mixed solution of a dialysis fluid, wherein the water inlet duct is configured to provide water to the dialysis preparation assembly for preparing said mixed solution of dialysis fluid. The fluid circuit further comprises an infusion preparation assembly comprising one or more concentrated sources housing a respective concentrate solution and configured to prepare a mixed solution of an infusion fluid, wherein the water inlet duct is configured to provide water to the infusion preparation assembly for preparing said mixed solution of infusion fluid.

Abstract: An apparatus for extracorporeal treatment of blood (1) has a supply line (2), a waste line (13) and an ultrafilter (19; 70) inserted in the supply line (2). An air inlet line is connected to the first chamber (21; 72) of the ultrafilter (19; 70) and a pressure sensor (41) configured for detecting pressure in the waste line (13). A controller (50) is configured to carry out, with the hydraulic circuit (100) in by-pass configuration, an integrity test procedure for detecting if the ultrafilter membrane has multiple or single fiber breaks. A method of testing the ultrafilter (19; 70) is also disclosed.

Abstract: An apparatus (1) for extracorporeal blood treatment comprises a filtration unit (2) having a primary chamber (3) and a secondary chamber (4) separated by a semi-permeable membrane (5), a blood circuit (17) comprising at least a blood withdrawal line (6) and a blood return line (7), a fluid circuit (32) comprising a fluid supply source (50) for providing a sterile fluid, and at least one gas inlet (49) to allow gas to enter into the blood circuit (17). The apparatus further comprises a control unit configured to perform a blood restitution procedure towards the patient for ending an extracorporeal blood treatment and before disconnecting the patient, said blood restitution procedure comprising the steps of infusing a predetermined amount of sterile fluid from the supply source (50) into the blood circuit (17) and causing a predetermined amount of gas to enter into the blood circuit (17) from the gas inlet (49).

Abstract: A mobile dialysis therapy cart includes a top shelf; a cycler compartment positioned below the top shelf, the cycler compartment sized and shaped to house an APD cycler; a fluid bag management compartment sized and shaped to house at least two fluid bags; a drain compartment positioned below the fluid bag management compartment; and a plurality of wheels. The cart may include a heating device associated with the fluid bag management compartment and/or a sanitizing light source for sanitizing a location of a disposable set associated with the fluid bags.

Abstract: An apparatus for extracorporeal treatment of blood (1) has a supply line (2), a waste line (13) and an ultrafilter (19; 70) inserted in the supply line (2). An air inlet line is connected to the first chamber (21; 72) of the ultrafilter (19; 70) and a pressure sensor (41) configured for detecting pressure in the waste line (13). A controller (50) is configured to carry out, with the hydraulic circuit (100) in by-pass configuration, an integrity test procedure for detecting if the ultrafilter membrane has multiple or single fiber breaks. A method of testing the ultrafilter (19; 70) is also disclosed.

Abstract: An apparatus for extracorporeal blood treatment, comprising a treatment unit (2) having a first chamber (3) and a second chamber (4) separated from one another by a semipermeable membrane (5), a blood removal line (6) connected in inlet with the first chamber (3) and a blood return line (7) connected in outlet with the first chamber; an infusion line (9;9a, 9b) of a replacement fluid and a fluid evacuation line (10) connected in outlet from the second chamber.

Abstract: An apparatus for extracorporeal blood treatment, comprising a treatment unit (2) having a first chamber (3) and a second chamber (4) separated from one another by a semipermeable membrane (5), a blood removal line (6) connected in inlet with the first chamber (3) and a blood return line (7) connected in outlet with the first chamber; an infusion line (9;9a, 9b) of a replacement fluid and a fluid evacuation line (10) connected in outlet from the second chamber.

Abstract: An apparatus for extracorporeal blood treatment, comprising a treatment unit (2) having a first chamber (3) and a second chamber (4) separated from one another by a semipermeable membrane (5), a blood removal line (6) connected in inlet with the first chamber (3) and a blood return line (7) connected in outlet with the first chamber; an infusion line (9; 9a, 9b) of a replacement fluid and a fluid evacuation line (10) connected in outlet from the second chamber.

Abstract: An apparatus is described for extracorporeal blood treatment, comprising a treatment unit, an extracorporeal blood circuit and a fluid evacuation line. The apparatus comprises a control unit connected to a pressure sensor and configured to move a blood pump, generating a variable flow with a constant component equal to a desired blood flow value and a variable component having a nil mean value; the variable flow generates, in the expansion chamber, a pressure progression that is variable over time with a pressure component oscillating about a mean value. The control unit receives a plurality of values over a period of time comprising a plurality of oscillations of the pressure about the mean value, calculates a control value representative of the oscillating pressure component, and then determines the verification or not of a condition of variation of the blood level in the expansion chamber.

Abstract: An apparatus is described for extracorporeal blood treatment, comprising a treatment unit, an extracorporeal blood circuit and a fluid evacuation line. The apparatus comprises a control unit connected to a pressure sensor and configured to move a blood pump, generating a variable flow with a constant component equal to a desired blood flow value and a variable component having a nil mean value; the variable flow generates, in the expansion chamber, a pressure progression that is variable over time with a pressure component oscillating about a mean value. The control unit receives a plurality of values over a period of time comprising a plurality of oscillations of the pressure about the mean value, calculates a control value representative of the oscillating pressure component, and then determines the verification or not of a condition of variation of the blood level in the expansion chamber.

Abstract: An apparatus is described for extracorporeal blood treatment (1), comprising a treatment unit (2), an extracorporeal blood circuit (8) and a fluid evacuation line (10). The apparatus comprises a control unit (21) connected with a pressure sensor (13, 14) and with a blood pump (9) and configured to move the blood pump (9), generating a variable flow with a constant component equal to a desired blood flow value and a variable component having a nil mean value; the variable flow generates, in the expansion chamber (11, 12), a progression of the pressure that is variable over time (P(t)) with a pressure component (?P) oscillating about a mean value (Pavg).

Abstract: An apparatus for extracorporeal blood treatment, comprising a treatment unit (2) having a first chamber (3) and a second chamber (4) separated from one another by a semipermeable membrane (5), a blood removal line (6) connected in inlet with the first chamber (3) and a blood return line (7) connected in outlet with the first chamber; an infusion line (9; 9a, 9b) of a replacement fluid and a fluid evacuation line (10) connected in outlet from the second chamber.

Abstract: An apparatus for extracorporeal blood treatment, comprising a treatment unit (2) having a first chamber (3) and a second chamber (4) separated from one another by a semipermeable membrane (5), a blood removal line (6) connected in inlet with the first chamber (3) and a blood return line (7) connected in outlet with the first chamber; an infusion line (9; 9a, 9b) of a replacement fluid and a fluid evacuation line (10) connected in outlet from the second chamber.

Abstract: In a process for testing filters (4) and (13) of treatment fluid of a hemodiafiltration apparatus (1), each filter has a wet semipermeable membrane (5, 14) which separates a gas-filled first chamber (6 and 15) from a liquid-filled second chamber (7 and 16). The first chambers are pressurized by a pump (19) supplying air, while the second chambers are placed in depression by a drainage pump (17) of used dialysis fluid. A first closed system is formed which includes the first chambers and a second closed system is formed which includes the second chambers. Two pressure gauges (P1 and P2) monitor the pressure in the two closed systems for a predetermined time. The monitoring provides indications relating to the filter integrity.