Abstract: The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.

Abstract: The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.

Abstract: The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.

Abstract: The invention concerns an internal standard used to quantitative analysis of the risk of humoral (i.e. vascular) transplant rejection. The internal standard consists of a stable composition of the C4d complement bound to a carrier consisting of erythrocytes or microparticles. The invention also concerns a method for analyzing in vitro the risk of humoral organ transplant rejection, which consists in determining the amount of component of C4d component fixed on the erythrocytes contained in a blood sample from a patient.

Abstract: The invention relates to a protein construct, comprising (i) a targeting moiety that is capable of binding to a target cell, and (ii) an effector immunogenic moiety that is capable of triggering an existing, vaccine-induced or natural, immune response. The protein construct, that is preferably in the form of a heteromultimeric protein, is useful for redirecting an immune response that was pre-existing in a patient, toward an undesired target cell.

Abstract: The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.

Abstract: A differential has a first element operatively connected to the output shaft for driving the wheels of the vehicle and a second element operatively connected to a prime mover. The differential includes a third element operatively connected to a fly wheel. The fly wheel and prime mover are arranged to simultaneously drive said output shaft through said differential so that the speed of the vehicle may remain constant or vary regardless of the speed of the fly wheel. The fly wheel is capable of being driven by a source external of the prime mover so that the fly wheel may assist the prime mover during acceleration of the vehicle.

Abstract: Raw mollusks at room temperature are fed to a crusher wherein a mechanical shock is introduced to the mollusks with the magnitude of the shock being sufficient to release attachment between the mollusk meat and the mollusk shell by rapidly accelerating and then rapidly decelerating the mollusks using a rotating roller having a minimum surface speed of about 2800 feet per minute. The mollusks are then separated into a first stream of loose meat and meat attached to shells and a second stream of loose meat and shells. Each stream is then subjected to centrifugal separation whereupon the first stream shells having meat attached thereto is recycled through a crusher.

Abstract: Raw mollusks at room temperature are fed to a crusher wherein a mechanical shock is introduced to the mollusks with the magnitude of the shock being sufficient to release attachment between the mollusk meat and the mollusk shell by rapidly accelerating and then rapidly decelerating the mollusks using a rotating roller having a minimum surface speed of about 2800 feet per minute.

Abstract: This invention is concerned with drills that are driven by electrical motors upon which there is movable chuck jaws for changing the size of the drill bit. The invention comprises of two parts, a drive sleeve, and a studded anchor ring. By means of the studded anchor ring, the operator is able to hold the spindle of the drill motionless so that it will not rotate, while by means of the drive sleeve, the outer cylinder of the chuck can be turned, thus locking or unlocking the jaws of the chuck to remove or insert the desired drill bit. The drive sleeve consists of a medium hard resilient type member, preferably made of rubber in the shape of a cylinder. The anchor ring cmprises a material also of a medium hard rubber or the like with three studs molded at intervals of 120 degrees apart on the inner surface. The studs engage the pivot hole in the spindle and prevent it from turning while the drive sleeve operates the opening and closing of the jaws of the chuck.