Patents by Inventor Mayumi Yoshida

Mayumi Yoshida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11275085
    Abstract: A problem of the present invention is to provide an immunochromatographic test strip avoiding agglutination of colloidal gold while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a hemagglutinating agent and the colloidal gold conjugates as a detection reagent, and to provide immunochromatography using the test strip. To solve the problem, the present inventors reviewed the composition of the existing reagent itself from a completely different viewpoint rather than the selection of type or amount of polyanions, and as a result of extensive study on each element, the inventors surprisingly found that agglutination of colloidal gold may be suppressed by using a particular additive without neutralization by polyanions.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: March 15, 2022
    Assignee: SEKISUI MEDICAL CO., LTD.
    Inventors: Keigo Kohno, Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Marie Asami
  • Patent number: 10658639
    Abstract: A polyolefin microporous membrane has excellent strength, permeability and heat resistance, which is obtained by using UHMwPE and employing a sequential stretching system, and a production method of the microporous membrane. In producing a microporous membrane by using a primary material A having a molecular weight (Mw) of less than 1.0×106, a secondary material B having a molecular weight of 1.0×106 or more, and a plasticizer, when the endothermic quantity of a mixture of the primary material and the plasticizer and the endothermic quantity of a mixture of the secondary material and the plasticizer are denoted as Q1 and Q2, respectively, respective resins are designed such that the ratio of endothermic quantity Q2 to endothermic quantity Q1 (endothermic quantity Q2/endothermic quantity Q1) becomes 1 or more over a temperature range of 110 to 118° C.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 19, 2020
    Assignee: Toray Industries, Inc.
    Inventors: Naoki Toyota, Mayumi Yoshida
  • Publication number: 20200081002
    Abstract: A problem of the present invention is to provide an immunochromatographic test strip avoiding agglutination of colloidal gold while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a hemagglutinating agent and the colloidal gold conjugates as a detection reagent, and to provide immunochromatography using the test strip. To solve the problem, the present inventors reviewed the composition of the existing reagent itself from a completely different viewpoint rather than the selection of type or amount of polyanions, and as a result of extensive study on each element, the inventors surprisingly found that agglutination of colloidal gold may be suppressed by using a particular additive without neutralization by polyanions.
    Type: Application
    Filed: August 13, 2019
    Publication date: March 12, 2020
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Keigo KOHNO, Mayumi YOSHIDA, Mitsuaki YAMAMOTO, Shinya YOKOKAWA, Marie ASAMI
  • Patent number: 10422799
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: September 24, 2019
    Assignee: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono
  • Patent number: 10422790
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventors reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventors surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: September 24, 2019
    Assignee: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono
  • Patent number: 10422798
    Abstract: A problem of the present invention is to provide an immunochromatographic test strip avoiding agglutination of colloidal gold while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a hemagglutinating agent and the colloidal gold conjugates as a detection reagent, and to provide immunochromatography using the test strip. To solve the problem, the present inventors reviewed the composition of the existing reagent itself from a completely different viewpoint rather than the selection of type or amount of polyanions, and as a result of extensive study on each element, the inventors surprisingly found that agglutination of colloidal gold may be suppressed by using a particular additive without neutralization by polyanions.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: September 24, 2019
    Assignee: SEKISUI MEDICAL CO., LTD.
    Inventors: Keigo Kohno, Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Marie Asami
  • Patent number: 10416156
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: September 17, 2019
    Assignee: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono
  • Patent number: 10151747
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: December 11, 2018
    Assignee: Sekisui Medical Co., Ltd.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono
  • Publication number: 20180267033
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Application
    Filed: December 19, 2017
    Publication date: September 20, 2018
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi YOSHIDA, Mitsuaki YAMAMOTO, Shinya YOKOKAWA, Tomo SHIMIZU, Keigo KONO
  • Publication number: 20180166670
    Abstract: A polyolefin microporous membrane has excellent strength, permeability and heat resistance, which is obtained by using UHMwPE and employing a sequential stretching system, and a production method of the microporous membrane. In producing a microporous membrane by using a primary material A having a molecular weight (Mw) of less than 1.0×106, a secondary material B having a molecular weight of 1.0×106 or more, and a plasticizer, when the endothermic quantity of a mixture of the primary material and the plasticizer and the endothermic quantity of a mixture of the secondary material and the plasticizer are denoted as Q1 and Q2, respectively, respective resins are designed such that the ratio of endothermic quantity Q2 to endothermic quantity Q1 (endothermic quantity Q2/endothermic quantity Q1) becomes 1 or more over a temperature range of 110 to 118° C.
    Type: Application
    Filed: June 1, 2016
    Publication date: June 14, 2018
    Inventors: Naoki Toyota, Mayumi Yoshida
  • Publication number: 20180120303
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Application
    Filed: December 22, 2017
    Publication date: May 3, 2018
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono
  • Patent number: 9885707
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Grant
    Filed: April 1, 2013
    Date of Patent: February 6, 2018
    Assignee: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono
  • Patent number: 9880164
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Grant
    Filed: April 1, 2013
    Date of Patent: January 30, 2018
    Assignee: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono
  • Publication number: 20170370926
    Abstract: A problem of the present invention is to provide an immunochromatographic test strip avoiding agglutination of colloidal gold while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a hemagglutinating agent and the colloidal gold conjugates as a detection reagent, and to provide immunochromatography using the test strip. To solve the problem, the present inventors reviewed the composition of the existing reagent itself from a completely different viewpoint rather than the selection of type or amount of polyanions, and as a result of extensive study on each element, the inventors surprisingly found that agglutination of colloidal gold may be suppressed by using a particular additive without neutralization by polyanions.
    Type: Application
    Filed: December 16, 2014
    Publication date: December 28, 2017
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Keigo KOHNO, Mayumi YOSHIDA, Mitsuaki YAMAMOTO, Shinya YOKOKAWA, Marie ASAMI
  • Publication number: 20170102379
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Application
    Filed: December 22, 2016
    Publication date: April 13, 2017
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi YOSHIDA, Mitsuaki YAMAMOTO, Shinya YOKOKAWA, Tomo SHIMIZU, Keigo KONO
  • Publication number: 20170082618
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Application
    Filed: November 29, 2016
    Publication date: March 23, 2017
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi YOSHIDA, Mitsuaki YAMAMOTO, Shinya YOKOKAWA, Tomo SHIMIZU, Keigo KONO
  • Publication number: 20150293087
    Abstract: Provided are: an immunoassay method in which the deviation from a theoretical value (hereinafter also referred to as “a reference value”), which may be caused when a diluted blood specimen is used as a sample, is reduced in an immunochromatographic method that is so designed that a blood specimen (whole blood, serum or plasma) is used directly as a sample without subjecting the blood specimen to any pretreatment such as a dilution treatment; and a reagent for use in the method. An immunochromatographic method performed on a blood specimen using an immunochromatographic device equipped with (1) a sample pad and (2) a membrane on which a component capable of specifically binding to an analyte is immobilized, arranged in the order of (1) and (2) from upstream, wherein hydroxyethyl starch is present in the measurement system.
    Type: Application
    Filed: September 30, 2013
    Publication date: October 15, 2015
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi YOSHIDA, Motoki MORITA, Mitsuaki YAMAMOTO
  • Patent number: 9080180
    Abstract: A technology for producing a pig edema disease vaccine at low cost and at high efficiency is developed. Specifically, a gene of a pig edema disease toxin protein (Stx2e protein) is efficiently expressed in plant cells to produce a plant vaccine for pig edema disease at low cost. An Stx2e protein including a secretory signal peptide derived from a plant added at an amino terminus is expressed in cells of a plant such as Lactuca sativa using the 5?-untranslated region of an alcohol dehydrogenase gene (ADH5?UTR) derived from a plant.
    Type: Grant
    Filed: March 25, 2008
    Date of Patent: July 14, 2015
    Assignees: IDEMITSU KOSAN CO., LTD., NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE
    Inventors: Kazutoshi Sawada, Takeshi Matsui, Sou-ichi Makino, Keiko Kawamoto, Mayumi Yoshida, Nobuo Yoshida, Kyoko Yoshida
  • Publication number: 20150086974
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Application
    Filed: April 1, 2013
    Publication date: March 26, 2015
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono
  • Publication number: 20150064692
    Abstract: A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.
    Type: Application
    Filed: April 1, 2013
    Publication date: March 5, 2015
    Applicant: SEKISUI MEDICAL CO., LTD.
    Inventors: Mayumi Yoshida, Mitsuaki Yamamoto, Shinya Yokokawa, Tomo Shimizu, Keigo Kono