Patents by Inventor Mazen Es-Sayed

Mazen Es-Sayed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxooxetanes as Fungicidal Agents
    Publication number: 20100234220
    Abstract: The present invention relates to compounds of the formula (I) below and to their agrochemically active salts and their use alone or in a mixture with other active compounds and/or auxiliaries and/or additives for controlling phytopathogenic fungi and other microorganisms in or on plants, to processes for preparing these compounds and mixtures, to intermediates of these processes and to seed treated with the compounds, salts or mixtures mentioned.
    Type: Application
    Filed: November 24, 2007
    Publication date: September 16, 2010
    Applicant: Bayer CropScience AG
    Inventors: Mazen Es-Sayed, Stefan Hillebrand, Welf-Burkhard Wiese, Astrid Ullmann-Koppold, Klaus Kunz, Peter Schreier, Martin Vaupel, Karl-Heinz Kuck, Ulrike Wachendorff-Neumann, Kerstin Ilg, Armin De Meijere, Oleg Larionov, Amos Mattes, Peter Dahmen
  • PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS
    Publication number: 20100144672
    Abstract: The present invention relates to pyrimidinylpyrazoles and their use as insecticides, and also to processes for their preparation and to compositions comprising such arylpyrazoles.
    Type: Application
    Filed: December 12, 2007
    Publication date: June 10, 2010
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Jens Frackenpohl, Olaf Gebauer, Silvia Cerezo-Galvez, Mazen Es-Sayed, Ulrich Görgens, Eva-Maria Franken, Olga Malsam, Stefan Schnatterer, Christian Arnold, Peter Lümmen, Hans-Georg Schwarz, Achim Hense, Stefan Werner
  • 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Patent number: 7704999
    Abstract: The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: April 27, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Ulrich Niewöhner, Maria Niewöhner, legal representative, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jörg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski
  • 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Patent number: 7696206
    Abstract: The application claims a compound of the formula or a salt, a hydrate, or a hydrate of a salt thereof. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of erectile dysfunction.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: April 13, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Ulrich Niewöhner, Maria Niewöhner, legal representative, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jorg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski
  • BISOXIMES AS FUNGICIDES
    Publication number: 20100022559
    Abstract: The invention relates to the novel use of bisoximes, some of which are known, for controlling unwanted microorganisms, and to processes for their preparation, and also to novel bisoximes, to processes for their preparation and to their use for controlling unwanted microorganisms and insects in crop protection and in the protection of materials.
    Type: Application
    Filed: December 11, 2007
    Publication date: January 28, 2010
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Silvia Cerezo-Galvez, Mazen Es-Sayed, Herbert Gayer, Oliver Guth, Stefan Herrmann, Kerstin Ilg, James Darren Mansfield, Amos Mattes, Ahmed Wahed Moradi, Hans-Georg Schwarz, Thomas Seitz, Astrid Ullmann-Koppold, Klaus-Günther Tietjen, Ulrike Wachendorff-Neumann, Peter Dahmen, Arnd Voerste, Eva-Maria Franken, Olga Malsam, Peter Lösel, Anne Suty-Heinze
  • 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20100016323
    Abstract: The application claims a compound of the formula or a salt, a hydrate, or a hydrate of a salt thereof. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of erectile dysfunction.
    Type: Application
    Filed: September 29, 2009
    Publication date: January 21, 2010
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Ulrich Niewöhner, Maria Niewöhner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jörg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski
  • Substituted 1H-pyrrole-2,5-diones
    Publication number: 20090099192
    Abstract: The invention relates to novel substituted 1H-pyrrole-2,5-diones of the formula (IA) in which A?, Ar? and R? are as defined in the description, to novel compositions for controlling animal pests based on substituted 1H-pyrrole-2,5-diones of the formulae (I) and (IA) in which A, A?, Ar, Ar?, R and R? are as defined in the description, and to processes for their preparation.
    Type: Application
    Filed: July 8, 2005
    Publication date: April 16, 2009
    Applicant: Bayer CropScience AG
    Inventors: Thomas Bretschneider, Mazen Es-Sayed, Reiner Fischer, Kristian Kather, Olga Malsam, Jorg Konze, Peter Losel, Erich Sanwald, Waltraud Hempel
  • 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Publication number: 20080113972
    Abstract: The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Application
    Filed: December 21, 2007
    Publication date: May 15, 2008
    Applicant: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewohner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jorg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski, Maria Niewohner
  • 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors, for treatment of hypertension
    Patent number: 7314871
    Abstract: The application claims a method for treating hypertension by administering an effective amount of a compound of the formula (I) wherein the variable groups are as defined in the specification and claims. These 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: January 1, 2008
    Assignee: Bayer Aktiengesellschaft
    Inventors: Maria Niewöhner, legal representative, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jörg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski, Ulrich Niewöhner, deceased
  • Pyridylpyrimidines for use as pesticides
    Patent number: 7238697
    Abstract: The present invention relates to novel pyridylpyrimidines of the formula in which R1, R2, X, n, Y, Z and R have the meanings given in the disclosure, to a plurality of processes for preparing these compounds, and to their use for controlling pests. This invention further relates to novel intermediates and process for their preparation.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: July 3, 2007
    Assignee: Bayer CropScience AG
    Inventors: Thomas Bretschneider, Mazen Es-Sayed, Rüdiger Fischer, Fritz Maurer, Christoph Erdelen, Peter Lösel
  • 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Patent number: 7122540
    Abstract: The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: October 17, 2006
    Assignee: Bayer HealthCare AG
    Inventors: Maria Niewöhner, legal representative, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jörg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Semo, Marc Nowakowski, Ulrich Niewöhner, deceased
  • Imidazotriazinones and the use thereof
    Patent number: 7098207
    Abstract: Novel imidazotriazinones of general formula a method for the production and the pharmaceutical use thereof are disclosed.
    Type: Grant
    Filed: January 5, 2005
    Date of Patent: August 29, 2006
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Maria Niewohner, legal representative, Mazen Es-Sayed, Thomas Lampe, Helmut Haning, Gunter Schmidt, Karl-Heinz Schlemmer, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn, Ulrich Niewohner, deceased
  • 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Publication number: 20060189615
    Abstract: The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Application
    Filed: April 21, 2006
    Publication date: August 24, 2006
    Applicant: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewohner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jorg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski
  • Imidazo[1,3,5]triazinones and their use
    Patent number: 7091203
    Abstract: The invention relates to imidazo[1,3,5]triazinones, a method for their production and methods of use, in particular as inhibitors of cyclic GMP metabolizing phosphodiesterases.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: August 15, 2006
    Assignee: Bayer Healthcare AG
    Inventors: Ulrich Niewöhner, Helmut Haning, Thomas Lampe, Mazen Es-Sayed, Gunter Schmidt, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Pyrazolyl pyrimidines
    Patent number: 7087616
    Abstract: This invention relates to novel pyrazolylpyrimidines of the formula in which R1, R2, X, n, Y, Z and R have the meanings given in the disclosure, to a plurality of processes for preparing these substances, and to their use for controlling pests.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: August 8, 2006
    Assignee: Bayer CropScience AG
    Inventors: Rüdiger Fischer, Bernd Alig, Thomas Bretschneider, Mazen Es-Sayed, Christoph Erdelen, Peter Lösel, Udo Reckmann
  • Novel imidazotriazinones and the use thereof
    Publication number: 20050267112
    Abstract: Novel imidazotriazinones of general formula a method for the production and the pharmaceutical use thereof are disclosed.
    Type: Application
    Filed: January 5, 2005
    Publication date: December 1, 2005
    Applicant: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewohner, Mazen Es-Sayed, Thomas Lampe, Helmut Haning, Gunter Schmidt, Karl-Heinz Schlemmer, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn, Maria Niewohner
  • 7-Alkyl and cycloalkyl-substituted imidazotriazinones
    Patent number: 6943163
    Abstract: The present invention relates to 7-alkyl- and cycloalkyl-substituted imidazotriazinones, to processes for their preparation and to their use as medicaments, in particular as inhibitors of cGMP-metabolizing phosphodiesterases.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: September 13, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewöhner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Gunter Schmidt, Karl-Heinz Schlemmer, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn
  • 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Patent number: 6890922
    Abstract: The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: May 10, 2005
    Assignee: Bayer Healthcare AG
    Inventors: Maria Niewohner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jörg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski, Ulrich Niewöhner
  • Triazolotriazinones and the use thereof
    Publication number: 20050096320
    Abstract: The invention relates to novel triazolotriazinones of the general formula and to a method for their production and pharmaceutical use thereof.
    Type: Application
    Filed: December 4, 2003
    Publication date: May 5, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Ulrich Niewohner, Helmut Haning, Thomas Lampe, Mazen Es-Sayed, Gunter Schmidt, Erwin Bischoff, Klaus Dembowsby, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Imidazotriazinones and the use thereof
    Patent number: 6878708
    Abstract: Novel imidazotriazinones of general formula (I), a method for the production and the pharmaceutical use thereof are disclosed.
    Type: Grant
    Filed: February 20, 2001
    Date of Patent: April 12, 2005
    Assignee: Bayer Aktiengesellschaft
    Inventors: Maria Niewöhner, Mazen Es-Sayed, Thomas Lampe, Helmut Haning, Gunter Schmidt, Karl-Heinz Schlemmer, Erwin Bischoff, Klaus Dembowsky, Elisabeth Perzborn, Ulrich Niewöhner