Abstract: A vascular access system can include a port configured to be implanted outside of a target body lumen, at least one conduit fluidly connected to the port, and at least one one-way valve proximate the distal end of the conduit and within the fluid pathway of the sidewall of the conduit. The system can also include a gateway element comprising a through lumen operably connected to an outer diameter of the conduit, the gateway element comprising a first radially compressed configuration in which the gateway element causes occlusion within the through lumen, and a second radially expanded configuration in which the gateway element permits passage of fluids within the through lumen.

Abstract: The present invention describes a non-invasive assay based on a key biomarkers that can be used to create a Radiation Response Index indicative of the tumor's response to radiation therapy prior to, during, and post-radiation therapy. The invention stratifies the subjects into clinically relevant categories, Radiation Resistant and Radiation Sensitive.

Abstract: Systems and methods for providing metric data for patterns in a modeling environment are disclosed. In some aspects, contexts for generating metric data for a pattern are constructed. The pattern represents one or more computations executable in the modeling environment and associated with operation or behavior of a real-world system. The contexts include information about the pattern. The metric data is associated with one or more objectives with which the use of the pattern is associated. Code for the pattern for each context is generated. Metric data is generated for the pattern and under each context. The metric data of the pattern under each context is associated with the objectives. The metric data and the association are stored for use in providing information about or based on the metric data when the pattern is to be or is used in a model representing the real-world system.

Abstract: Systems and methods for uniquely identifying and regularly authenticating users at login are disclosed. A method may include an authentication computer program receiving a user identifier for a user as part of a login attempt from a workstation computer program; communicating a multifactor authentication request to an authenticator application executed on a user mobile electronic device; receiving a response to the multifactor authentication request from the authenticator application; verifying that the response to the multifactor authentication request matches an expected value; and saving user activity data associated with the login attempt, and a user trust computer program calculating a user trust score based on the user activity data; determining that the user trust score is above a threshold; and authorizing the login attempt to the workstation and a user session on the workstation.

Abstract: A method (500) for managing nausea includes receiving, from one or more monitoring devices (200), patient parameter data (212) of a patient (10). The patient parameter data is collected by the one or more monitoring devices. The method also includes determining, based on the patient parameter data of the patient, whether the patient is experiencing or about to experience an episode of nausea. When the patient is experiencing or about to experience an episode of nausea, the method also includes communicating one or more therapy signals (302, 304, 306, 308) to a receiver device (12, 21, 400) in communication with the computing device.

Abstract: A process for document processing (e.g., automated package splitting) may involve producing, for each document page of an ordered plurality of document pages, an image of the document page and a representation of text from the document page; generating, for each document page of the ordered plurality, and based on the image of the document page and the representation of text from the document page, an embedding of the document page; and generating, for each document page among a subset of the ordered plurality, a label for the document page that indicates whether the document page is a document first page, based on the embedding of the document page, the embedding of each of at least one document page that precedes the document page in the ordered plurality, and the embedding of each of at least one document page that follows the document page in the ordered plurality.

Abstract: A method of image quality assessment, performed by one or more processors in an image capture device, is disclosed. The method comprising receiving notification of capture of an image and in response, initiating an image assessment task to assess the quality of the image. The assessment task comprises determining suitability of the image for image quality assessment, running an image quality assessment model on the image to generate image quality assessment results, collecting data related to the capture of the image, and transmitting the results to an image quality assessment repository. The image assessment task may be a lower priority asynchronous task.

Abstract: A process for document processing (e.g., automated package splitting) may involve producing, for each document page of an ordered plurality of document pages, an image of the document page and a representation of text from the document page; generating, for each document page of the ordered plurality, and based on the image of the document page and the representation of text from the document page, an embedding of the document page; and generating, for each document page among a subset of the ordered plurality, a label for the document page that indicates whether the document page is a document first page, based on the embedding of the document page, the embedding of each of at least one document page that precedes the document page in the ordered plurality, and the embedding of each of at least one document page that follows the document page in the ordered plurality.

Abstract: Systems and methods for providing metric data for patterns in a modeling environment are disclosed. In some aspects, contexts for generating metric data for a pattern are constructed. The pattern represents one or more computations executable in the modeling environment and associated with operation or behavior of a real-world system. The contexts include information about the pattern. The metric data is associated with one or more objectives with which the use of the pattern is associated. Code for the pattern for each context is generated. Metric data is generated for the pattern and under each context. The metric data of the pattern under each context is associated with the objectives. The metric data and the association are stored for use in providing information about or based on the metric data when the pattern is to be or is used in a model representing the real-world system.

Abstract: In some embodiments, techniques for self-labeling to extract a representative set of samples from a large-scale set of unlabeled documents (e.g., a set that represents a distribution of the large-scale set) are provided. The samples of the representative set may then be used to classify the documents of the large-scale set.

Abstract: State of the art systems used for airport automation and data processing may be prone to data security related issues, as unauthorized personal may gain entry to sensitive data. The disclosure herein generally relates to airport management, and, more particularly, to a method and system for service authentication in an airport management network. The system uses a neural network to process a received service request and decides whether the service request is to be allowed or denied, based on a determined validity of the service request, role based access defined for a user requesting the service, a feature map data generated.

Abstract: This disclosure relates to field of cryptography and digital signatures. The constant theft of cryptocurrencies is due to compromise of the secret signing key inherently stored in a single location. Also, one of challenges in the existing ECDSA signature is single point failure, wherein the signing key (private key) is prone to theft. The disclosed technique overcomes the challenging in the existing techniques by party distributed signature that ensures the safety of the private key. The disclosed techniques slits the key in two parts and saves at two different locations/machines. Further based on a ECDSA based technique, the digital signature is obtained securely using several steps that includes generation of first two parts of digital signature at one party, generation of the second two parts of digital signature at second party, finally decrypting a complete digital signature at the first party.

Abstract: Techniques disclosed herein provide a method of informing blood product administration to a perioperative patient. Some patients may be at risk of perioperative bleeding following a surgery, such as a cardiac surgery. As discussed herein, coagulation status of a patient is monitored perioperatively and at least one value indicative of the coagulation status may be used to determine the patient’s risk of perioperative bleeding. Should the patient’s risk of perioperative bleeding be determined to be sufficiently high, such as when the value(s) are below one or more thresholds, techniques disclosed herein may also in some embodiments aid in titration of a blood product to be administered to the perioperative patient to adjust the patient’s risk of bleeding.

Abstract: A method for updating a localization of an autonomous vehicle includes receiving perception input data from a sensor of the autonomous vehicle and receiving map data including road lane information in a vicinity of the autonomous vehicle. The method includes processing the perception input data to extract perceived road lane information including a perceived x position, a perceived y position, a perceived z position, a perceived lane type, a perceived lane color, and a perceived lane curvature and processing the map data to extract map road lane information including a map x position, a map y position, a map z position, a map lane type, a map lane color, and a map lane curvature. The method includes calculating a transformation matrix from the perceived road lane information and the map road lane information and updating the map data and a localization of the vehicle based on the transformation matrix.

Abstract: Transaction executions/commits in a blockchain network need to be fast, robust and secure and thus calls for minimal latency in transaction commits. In an execute-order-commit blockchain network, latency is high due to smart contracts been executed at every endorsing node of the blockchain network. A method and system for processing transactions in the blockchain network is disclosed. The system discloses a veriblock architecture, which enables processing a transaction request by executing an associated smart contract along with a proof of correctness of execution of smart contract using only one endorser. Further, enables verifying the smart contract by multiple endorsers. The smart contract associated with the proof, referred herein as a vericontract, is executed to generate an output and the proof using one of a) Verifiable Computing (VC) approach, b) a TEE approach and c) a hybrid approach (combination of VC and TEE).

Abstract: A method for using encryption and tokenization to protect confidential data that is stored in a public cloud database is provided. The method includes: receiving a first data set; tokenizing the first data set; obtaining a first token for at least one attribute of the first data set; encrypting an original value of the attribute and the first data set; storing each of the original value of the at least one attribute, the encrypted value of the at least one attribute, and the first token in a first memory; storing each of the first token and the encrypted first data set in a second memory; and storing the tokenized first data set in a third memory that is hosted on a public cloud server.

Abstract: The invention relates to methods and products for the identification of a clinically significant immune response in subjects treated with a therapeutic protein. Aspects of the invention relate to methods and compositions for identifying a clinically significant immune response in patients treated with therapeutic amounts of a VLA4 binding antibody (e.g., natalizumab).

Abstract: Examples provide on-time delivery prediction generation using a machine learning element for orders obtained from an order management component. The obtained order is analyzed to identify a plurality of order attributes. An initial value for each order attribute in the plurality of order attributes is calculated based on sensor data and telemetry data. An initial order-score for the obtained order is determined based on the initial values for each order attribute in the plurality of order attributes. An alternative order-score for the order is calculated after identifying an order attribute variable for the order and calculating updated values for each order attributes in the plurality of order attributes. After outputting the initial order-score and the alternative order-score for the order, with an indication of the order attribute variable associated with the alternative order-score, feedback for the order is received.

Abstract: An electronic stethoscope uses a contact sensor to confirm continuous contact with a patient. A recording of body sounds is begun while a timer is initiated. Upon a signal from the timer, recording is terminated. The duration of the timer may be set remotely by a practitioner. Additionally, the contact sensor may require a minimum level of force as an implicit indication that the stethoscope is firmly stationary. Once a valid measurement is recorded, it is analyzed in comparison to a baseline. Artificial intelligence is used to select the appropriate from a database of sampled data. Bootstrapping is used to develop additional data sets and Random Forest algorithm is used to select the appropriate baseline from the data. The current recording is analyzed with respect to the AI selected baseline. A display on the electronic stethoscope displays analyzed results as well as providing the visual aspect of a user interface.

Abstract: The present invention relates to chirally controlled oligonucleotides, chirally controlled oligonucleotide compositions, and the method of making and using the same. The invention specifically encompasses the identification of the source of certain problems with prior methodologies for preparing chiral oligonucleotides, including problems that prohibit preparation of fully chirally controlled compositions, particularly compositions comprising a plurality of oligonucleotide types. In some embodiments, the present invention provides chirally controlled oligonucleotide compositions. In some embodiments, the present invention provides methods of making chirally controlled oligonucleotides and chirally controlled oligonucleotide compositions.