Abstract: The present disclosure is related to a printing driver unit, which discloses method and printer driver unit for performing a transaction by automatically transmitting data to an Electronic Data Capture (EDC) terminal. Method includes receiving, by printer driver unit associated with host computing device, first print request including first data related to purchase, from host computing device. Further, the printer driver unit extracts final transaction amount from first data and determines status of EDC terminal upon extracting final transaction amount. When EDC terminal is determined to be in first state, the printer driver unit generates a second print request including extracted final transaction amount and transmits the generated second print request to EDC terminal to facilitate automatic insertion of final transaction amount in EDC terminal to initiate payment transaction.

Abstract: Alternative splicing events in SCN1A gene can lead to non-productive mRNA transcripts which in turn can lead to aberrant protein expression, and therapeutic agents which can target the alternative splicing events in SCN1A gene can modulate the expression level of functional proteins in Dravet Syndrome patients and/or inhibit aberrant protein expression. Such therapeutic agents can be used to treat a condition caused by SCN1A, SCN8A or SCN5A protein deficiency.

Abstract: A method for managing a memory by an electronic device, and the electronic device, are provided. The method includes detecting a plurality of applications being executed and using the memory of the electronic device, determining a priority for each application of the plurality of applications, determining at least one page from a plurality of pages of at least one application from the plurality of applications to be dropped based on at least one priority associated with the at least one application, and dropping the at least one page from the plurality of pages of the at least one application.

Abstract: Systems and methods for digital identity verification are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for digital identify verification may include: (1) receiving, from a user electronic device or at a website, an image of an identity document for a user, the identity document comprising an image of the user; (2) processing the identity document with at least one business-specific rule; (3) extracting identity information from the identity document; (4) determining a match rate of the image of the user on the identity document to a captured image; (5) assigning a verification score to the user based on extracted identity information and the match rate; and (6) publishing the verification score to at least one system.

Abstract: A method is provided for converting a single database query into multiple database queries for multiple databases and aggregating the results of each of the queries. The method includes receiving, from a calling device, an input database query including a selection set defining an aggregation key, at least one first field to be queried in a first database, and at least one second field to be queried in a second database, generating a first database query representing a first request to retrieve the at least one first field from the first database, generating a second database query representing a second request to retrieve the at least one second field from the second database, aggregating the first response and a second response to the second database query from the first database to produce an aggregated response, and providing the aggregated response to the calling device.

Abstract: A method for automatically capturing and processing an image of a user is provided. The method includes determining a level of an emotion identified from a multimedia content; determining an adjusted emotion level by adjusting the level of the emotion based on user information; capturing a plurality of images of the user over a period of time, based on the adjusted emotion level being greater than a first threshold and a reaction of the user determined based on the plurality of images, being less than a second threshold; prioritizing the plurality of images based on at least one of a frame emotion level of the plurality of images, facial features of the user in the plurality of images, or a number of faces in the plurality of images; and processing the prioritized images to generate an output.

Abstract: Fascia activation and training devices having an adjustable length, collapsible, elongate device body having opposing ends to which open ended interchangeable cuffs are removably mounted. The end cuffs of the training devices provide for inward and/or outward compression forces to be applied by a user's body members engaging such end cuffs, thereby enhancing fascial activation and training, and providing users with proprioceptive feedback, making motor learning in biomechanical retraining through fascia remodeling possible. Methods of use of such training devices provide for the use of multiple types of training devices in combination, resulting in the enhanced training of biomechanical chains of muscles.

Abstract: Systems and methods for providing metric data for patterns in a modeling environment are disclosed. In some aspects, contexts for generating metric data for a pattern are constructed. The pattern represents one or more computations executable in the modeling environment and associated with operation or behavior of a real-world system. The contexts include information about the pattern. The metric data is associated with one or more objectives with which the use of the pattern is associated. Code for the pattern for each context is generated. Metric data is generated for the pattern and under each context. The metric data of the pattern under each context is associated with the objectives. The metric data and the association are stored for use in providing information about or based on the metric data when the pattern is to be or is used in a model representing the real-world system.

Abstract: Embodiments of the invention utilize an optimized key-value storage engine to strike the optimal balance between cloud-cost and performance and supports queries, including updates, lookups, range queries, inserts, and read-modify-writes. Cloud cost is manifested in purchasing both storage and processing resources. The improved approach has the ability to self-design and instantiate holistic configurations given a workload, a cloud budget, and optionally performance goals and a set of Service Level Agreement (SLA) specifications. A configuration reflects an optimized storage engine design in terms of, for example, the individual data structures design (in-memory and on-disk) in the engine as well as their algorithms and interactions, a cloud provider, and the exact virtual machines to be used.

Abstract: The invention relates to a system (300) and method for performing end-to-end simulation and testing of an IoT application (102). An IoT data simulator (310) is configured to simulate an IoT environment using data received from different components in the IoT environment, which include IoT messages/data from IoT devices (106), master data from different databases (108) and data from third-party web services (110). Device templates are created that are used as blueprint for defining a plurality of device instances which include simulated device instances and live device instances. An IoT application validator (326) is configured for testing and validating the IoT application (102) by transmitting a plurality of IoT messages to the IoT application (102) and validating the behavior of the IoT application (102) to the plurality of IoT messages for all layers including, but not limited to, a UI layer (112), a business logic (114) and a data layer (116), using one or more device instances.

Abstract: A method for generating a slow motion video. The method includes segmenting, by an electronic device, objects in the video. Further, the method includes determining, by the electronic device, an interaction between the segmented objects. Further, the method includes clustering, by the electronic device, the segmented objects in the video to generate object clusters based on the interaction. Further, the method includes determining, by the electronic device, a degree of slow motion effect to be applied to each of the object clusters in the video based on a significance score of each of the object clusters. Further, the method includes generating, by the electronic device, the slow motion video by applying the degree of slow motion effect to that has been determined to corresponding the object clusters.

Abstract: Systems and methods for digital identity verification are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for digital identify verification may include: (1) receiving, from a user electronic device or at a website, an image of an identity document for a user, the identity document comprising an image of the user; (2) processing the identity document with at least one business-specific rule; (3) extracting identity information from the identity document; (4) determining a match rate of the image of the user on the identity document to a captured image; (5) assigning a verification score to the user based on extracted identity information and the match rate; and (6) publishing the verification score to at least one system.

Abstract: The present disclosure relates to a series of tricyclic compounds, their tautomers, polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of treating conditions and diseases that are mediated by adenosine receptor (AR) activity. The disclosure also relates to process of preparation of these tricyclic compounds of Formula I. These compounds are useful in the treatment, prevention or suppression of diseases and disorders that may be susceptible to improvement by antagonism of the adenosine receptor. The disclosure also relates to the process of preparation of the tricyclic compounds, and to pharmaceutical compositions containing them.

Abstract: The invention relates to methods and reagents for analyzing samples for the presence of JC virus antibodies.

Abstract: The invention relates to a system (300) and method for performing end-to-end simulation and testing of an IoT application (102). An IoT data simulator (310) is configured to simulate an IoT environment using data received from different components in the IoT environment, which include IoT messages/data from IoT devices (106), master data from different databases (108) and data from third-party web services (110). Device templates are created that are used as blueprint for defining a plurality of device instances which include simulated device instances and live device instances. An IoT application validator (326) is configured for testing and validating the IoT application (102) by transmitting a plurality of IoT messages to the IoT application (102) and validating the behavior of the IoT application (102) to the plurality of IoT messages for all layers including, but not limited to, a UI layer (112), a business logic (114) and a data layer (116), using one or more device instances.

Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).

Abstract: The present invention provides methods to improve a cancer patient's response to immune checkpoint inhibitor (ICI) therapy, and functional test to predict likelihood of response. Specifically, the invention provides methods to improve patient's response to immune checkpoint inhibitors using modulators and to predict response to the combination of immune checkpoint inhibitors and modulators.

Abstract: This invention relates to methods of increasing the sensitivity of tumors to anti cancer therapies including antibody therapy, chemotherapy, radiotherapy, and therapies targeting cell signaling pathways such as the MAPK and PI3K pathways and receptor tyrosine kinases (e.g. EGFR). By increasing sensitivity of tumors to these agents, this invention will: (a)Prolong response in already responsive subjects; (b) Increase response rates by converting non-responsive patients into responsive patients; (c) Reverse treatment-induced resistance of tumors to anticancer therapy; and (d) Decrease treatment-associated toxicities by decreasing therapy dosages required for response. The invention also describes predictive tests, to identify patients most likely to respond to the combination treatments.

Abstract: A method is provided for converting a single database query into multiple database queries for multiple databases and aggregating the results of each of the queries. The method includes receiving, from a calling device, an input database query including a selection set defining an aggregation key, at least one first field to be queried in a first database, and at least one second field to be queried in a second database, generating a first database query representing a first request to retrieve the at least one first field from the first database, generating a second database query representing a second request to retrieve the at least one second field from the second database, aggregating the first response and a second response to the second database query from the first database to produce an aggregated response, and providing the aggregated response to the calling device.

Abstract: Fascia activation and training devices having an adjustable length, collapsible, elongate device body having opposing ends to which open ended interchangeable cuffs are removably mounted. The end cuffs of the training devices provide for inward and/or outward compression forces to be applied by a user's body members engaging such end cuffs, thereby enhancing fascial activation and training, and providing users with proprioceptive feedback, making motor learning in biomechanical retraining through fascia remodeling possible. Methods of use of such training devices provide for the use of multiple types of training devices in combination, resulting in the enhanced training of biomechanical chains of muscles.