Patents by Inventor MEILING ZHANG

MEILING ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11952582
    Abstract: Provided are a mutant HPPD polypeptide having high resistance to a herbicide and an encoding gene thereof, and an application thereof in an improved plant. The amino acid at position 282 of the mutant HPPD polypeptide is mutated from arginine to serine at a wild-type HPPD polypeptide. In addition, the mutant HPPD polypeptide further comprises an amino acid at position 349 that is mutated from glutamic acid to lysine, and/or an amino acid at position 156 that is mutated from alanine to valine. The mutated HPPD polypeptide can be used for cultivating plants having resistance to a herbicide having HPPD inhibition.
    Type: Grant
    Filed: November 23, 2018
    Date of Patent: April 9, 2024
    Assignee: CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES
    Inventors: Jiankang Zhu, Vipasha Verma, Feng Li, Meiling Zhang, Ming Li, Mei Chen
  • Publication number: 20230320332
    Abstract: Provided are genetically modified non-human animals that express a human or chimeric (e.g., humanized) CCR8, and methods of use thereof.
    Type: Application
    Filed: September 10, 2021
    Publication date: October 12, 2023
    Inventors: Yuelei SHEN, Yang BAI, Chaoshe GUO, Meiling ZHANG, Rui HUANG, Chengzhang SHANG
  • Publication number: 20230172171
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD94 and/or NKG2A, and methods of use thereof.
    Type: Application
    Filed: May 21, 2021
    Publication date: June 8, 2023
    Inventors: Yuelei Shen, Yang Bai, Chaoshe Guo, Meiling Zhang, Rui Huang, Chengzhang Shang
  • Publication number: 20230148575
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) IL1B and/or IL1A, and methods of use thereof.
    Type: Application
    Filed: April 7, 2021
    Publication date: May 18, 2023
    Inventors: Yuelei Shen, Meiling Zhang, Rui Huang, Yang Bai, Chaoshe Guo, Xiaofei Zhou
  • Publication number: 20230072216
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) major histocompatibility complex (MHC) protein complex, and methods of use thereof.
    Type: Application
    Filed: January 8, 2021
    Publication date: March 9, 2023
    Inventors: Yuelei Shen, Chaoshe Guo, Meiling Zhang, Rui Huang, Yanan Guo, Yang Bai, Jiawei Yao, Chengzhang Shang
  • Publication number: 20230058049
    Abstract: This disclosure relates to genetically modified immunodeficient animals which express a human or chimeric (e.g., humanized) SIRP? and/or human or chimeric (e.g., humanized) CD47, and methods of use thereof.
    Type: Application
    Filed: December 31, 2020
    Publication date: February 23, 2023
    Inventors: Yuelei Shen, Yang Bai, Jiawei Yao, Chaoshe Guo, Meiling Zhang, Rui Huang, Yanan Guo, Chengzhang Shang
  • Publication number: 20230043907
    Abstract: Provided are a humanized transgenic non-human animal, especially a rodent, in particular a transgenic mouse containing a human interleukin 17A (IL-17A) gene, a human gene 17RA (IL-17RA) and/or a human TNF-alpha gene, and a preparation method therefor and the use thereof.
    Type: Application
    Filed: August 1, 2022
    Publication date: February 9, 2023
    Inventors: Yuelei Shen, Chaoshe Guo, Yanan Guo, Yang Bai, Rui Huang, Lei Zhao, Xiaofei Zhou, Meiling Zhang, Jiawei Yao
  • Patent number: 11564381
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) LAG3, and methods of use thereof.
    Type: Grant
    Filed: September 1, 2020
    Date of Patent: January 31, 2023
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Jiawei Yao, Chaoshe Guo, Yanan Guo, Yang Bai, Rui Huang, Lei Zhao, Meiling Zhang
  • Publication number: 20220408704
    Abstract: The present disclosure relates to genetically modified non-human animals expressing human or chimeric (e.g., humanized) Thrombopoietin (THPO), and methods of use thereof.
    Type: Application
    Filed: October 30, 2020
    Publication date: December 29, 2022
    Inventors: Yuelei Shen, Rui Huang, Yanan Guo, Yang Bai, Jiawei Yao, Chaoshe Guo, Meiling Zhang
  • Patent number: 11534502
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric TIGIT (e.g., humanized TIGIT), and methods of use thereof.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: December 27, 2022
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Yang Bai, Rui Huang, Yanan Guo, Xiaofei Zhou, Meiling Zhang
  • Publication number: 20220378025
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) IL10R and/or a human or chimeric (e.g., humanized) IL10, and methods of use thereof.
    Type: Application
    Filed: November 11, 2020
    Publication date: December 1, 2022
    Inventors: Yuelei Shen, Yanan Guo, Yang Bai, Jiawei Yao, Chaoshe Guo, Meiling Zhang, Rui Huang, Lei Zhao, Xiaofei Zhou
  • Patent number: 11505806
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric OX40, and methods of use thereof.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: November 22, 2022
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Chaoshe Guo, Yang Bai, Jiawei Yao, Meiling Zhang, Xiaofei Zhou
  • Patent number: 11497198
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD40, and methods of use thereof.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: November 15, 2022
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Chaoshe Guo, Rui Huang, Lei Zhao, Yanan Guo, Yang Bai, Meiling Zhang, Jiawei Yao
  • Publication number: 20220346357
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) TNFR2, and methods of use thereof.
    Type: Application
    Filed: September 4, 2020
    Publication date: November 3, 2022
    Inventors: Yuelei Shen, Rui Huang, Yanan Guo, Yang Bai, Lei Zhao, Jiawei Yao, Chaoshe Guo, Meiling Zhang
  • Patent number: 11464876
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric TIGIT (e.g., humanized TIGIT), and methods of use thereof.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: October 11, 2022
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Yang Bai, Rui Huang, Yanan Guo, Xiaofei Zhou, Meiling Zhang
  • Publication number: 20220312749
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) IL2RA, and methods of use thereof.
    Type: Application
    Filed: August 7, 2020
    Publication date: October 6, 2022
    Inventors: Yuelei Shen, Yang Bai, Chengzhang Shang, Rui Huang, Meiling Zhang, Jiawei Yao, Chaoshe Guo, Yanan Guo
  • Patent number: 11439132
    Abstract: Provided are a humanized transgenic non-human animal, especially a rodent, in particular a transgenic mouse containing a human interleukin 17A (IL-17A) gene, a human gene 17RA (IL-17RA) and/or a human TNF-alpha gene, and a preparation method therefor and the use thereof.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: September 13, 2022
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Chaoshe Guo, Yanan Guo, Yang Bai, Rui Huang, Lei Zhao, Xiaofei Zhou, Meiling Zhang, Jiawei Yao
  • Patent number: 11438027
    Abstract: A base station antenna and a base station including the base station antenna are provided. A base station antenna includes a transceiver array configured to output M signals, wherein M is an integer greater than 1; an antenna array including N antenna units, wherein N is an integer greater than M; a first-level signal allocating network configured to allocate first power to the M signals, and output P signals, wherein P is an integer greater than M; a signal synthesizing network including multiple signal synthesizers, wherein each of the multiple signal synthesizers utilizes two signals of the P signals to synthesize two output signals; and a second-level signal allocating network configured to allocate second power to signals output by the multiple signal synthesizers, and output N signals to the N antenna units.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: September 6, 2022
    Inventors: Lin Chen, Meiling Zhang, Qin Li, Wei Jiang, Jia Yan, Shaomin Zhang
  • Patent number: D968331
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: November 1, 2022
    Assignee: SHENZHEN YIGOOD TECHNOLOGY CO., LTD.
    Inventor: Meiling Zhang
  • Patent number: D1052532
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: November 26, 2024
    Assignee: SHENZHEN YIGOOD TECHNOLOGY CO., LTD.
    Inventors: Meiling Zhang, Deyong Zhang