Patents by Inventor MEILING ZHANG

MEILING ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GENES
    Publication number: 20210045367
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) IL4R and/or IL4, and methods of use thereof.
    Type: Application
    Filed: September 2, 2020
    Publication date: February 18, 2021
    Inventors: Yuelei Shen, Yanan Guo, Yang Bai, Rui Huang, Xiaofei Zhou, Chengzhang Shang, Meiling Zhang, Jiawei Yao, Chaoshe Guo
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC LAG3
    Publication number: 20210045366
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) LAG3, and methods of use thereof.
    Type: Application
    Filed: September 1, 2020
    Publication date: February 18, 2021
    Inventors: Yuelei Shen, Jiawei Yao, Chaoshe Guo, Yanan Guo, Yang Bai, Rui Huang, Lei Zhao, Meiling Zhang
  • Immunodeficient non-human animal
    Patent number: 10820580
    Abstract: The present disclosure relates to the genetically modified non-human animals that have a disruption at the endogenous CD132 gene (e.g., CD132 knockout), and methods of use thereof.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: November 3, 2020
    Assignee: Beijing Biocytogen Co., Ltd
    Inventors: Yuelei Shen, Yang Bai, Meiling Zhang, Jiawei Yao, Rui Huang, Yanan Guo
  • Genetically Modified Non-Human Animal With Human Or Chimeric OX40
    Publication number: 20190373866
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric OX40, and methods of use thereof.
    Type: Application
    Filed: May 31, 2019
    Publication date: December 12, 2019
    Inventors: Yuelei Shen, Chaoshe Guo, Yang Bai, Jiawei Yao, Meiling Zhang, Xiaofei Zhou
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC PD-1
    Publication number: 20190373868
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) programmed cell death protein 1 (PD-1), and methods of use thereof.
    Type: Application
    Filed: June 10, 2019
    Publication date: December 12, 2019
    Inventors: Yuelei Shen, Yanan Guo, Yang Bai, Rui Huang, Xiaofei Zhou, Meiling Zhang, Jiawei Yao, Chaoshe Guo
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC SIRPa
    Publication number: 20190373867
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) SIRP?, and methods of use thereof.
    Type: Application
    Filed: June 10, 2019
    Publication date: December 12, 2019
    Inventors: Yuelei Shen, Yang Bai, Meiling Zhang, Rui Huang, Chengzhang Shang, Yanan Guo
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GITR
    Publication number: 20190364861
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) glucocorticoid-induced TNFR-related protein (GITR), and methods of use thereof.
    Type: Application
    Filed: June 7, 2019
    Publication date: December 5, 2019
    Inventors: Yuelei Shen, Yanan Guo, Yang Bai, Jiawei Yao, Rui Huang, Lei Zhao, Meiling Zhang
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC TIM-3
    Publication number: 20190357506
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric (e.g., humanized) T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), and methods of use thereof.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 28, 2019
    Inventors: Yuelei Shen, Jian Ni, Yanan Guo, Rui Huang, Meiling Zhang, Lei Zhao, Yang Bai
  • Genetically Modified Non-Human Animal With Human Or Chimeric TIGIT
    Publication number: 20190351075
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric TIGIT (e.g., humanized TIGIT), and methods of use thereof.
    Type: Application
    Filed: May 31, 2019
    Publication date: November 21, 2019
    Inventors: Yuelei Shen, Yang Bai, Rui Huang, Yanan Guo, Xiaofei Zhou, Meiling Zhang
  • Genetically Modified Non-Human Animal With Human Or Chimeric OX40
    Publication number: 20190352666
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric OX40, and methods of use thereof.
    Type: Application
    Filed: August 30, 2017
    Publication date: November 21, 2019
    Inventors: Yuelei Shen, Chaoshe Guo, Yang Bai, Jiawei Yao, Meiling Zhang, Xiaofei Zhou
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD137
    Publication number: 20190343095
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD137, and methods of use thereof.
    Type: Application
    Filed: June 7, 2019
    Publication date: November 14, 2019
    Inventors: Yuelei Shen, Yanan Guo, Yang Bai, Lei Zhao, Rui Huang, Jiawei Yao, Meiling Zhang
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD27
    Publication number: 20190343096
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD27, and methods of use thereof.
    Type: Application
    Filed: June 7, 2019
    Publication date: November 14, 2019
    Inventors: Yuelei Shen, Yang Bai, Rui Huang, Chengzhang Shang, Yanan Guo, Meiling Zhang
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD40
    Publication number: 20190343098
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD40, and methods of use thereof.
    Type: Application
    Filed: June 7, 2019
    Publication date: November 14, 2019
    Inventors: Yuelei Shen, Chaoshe Guo, Rui Huang, Lei Zhao, Yanan Guo, Yang Bai, Meiling Zhang, Jiawei Yao
  • GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD28
    Publication number: 20190335728
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD28, and methods of use thereof.
    Type: Application
    Filed: June 7, 2019
    Publication date: November 7, 2019
    Inventors: Yuelei Shen, Yang Bai, Yanan Guo, Meiling Zhang, Rui Huang, Chengzhang Shang, Jiawei Yao
  • Genetically Modified Non-Human Animal With Human Or Chimeric TIGIT
    Publication number: 20190328907
    Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric TIGIT (e.g., humanized TIGIT), and methods of use thereof.
    Type: Application
    Filed: August 30, 2017
    Publication date: October 31, 2019
    Inventors: Yuelei Shen, Yang Bai, Rui Huang, Yanan Guo, Xiaofei Zhou, Meiling Zhang
  • IMMUNODEFICIENT NON-HUMAN ANIMAL
    Publication number: 20190320631
    Abstract: The present disclosure relates to the genetically modified non-human animals that have a disruption at the endogenous CD132 gene (e.g., CD132 knockout), and methods of use thereof.
    Type: Application
    Filed: June 7, 2019
    Publication date: October 24, 2019
    Inventors: Yuelei Shen, Yang Bai, Meiling Zhang, Jiawei Yao, Rui Huang, Yanan Guo
  • Fast startup control circuit for switch mode power supply
    Patent number: 9991787
    Abstract: A control circuit for a switch mode power supply (SMPS) includes a power switch for coupling to a primary winding of the power supply and a startup resistor coupled to an external input voltage and to a control terminal of the power switch. The control circuit also includes a controller. During startup, the controller is configured to cause the power switch to amplify a startup current from an external input voltage through the startup resistor and provide a startup power to the controller. During normal operation, the controller is configured to provide a power switch control signal to turn on and off the power switch for controlling a current flow in the primary winding and regulating an output of the power supply. The controller is configured to provide a current signal for driving an NPN power switch and to provide a voltage signal for driving an NMOS power switch.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: June 5, 2018
    Assignee: SHANGHAI SIM-BCD SEMICONDUCTOR MANUFACTURING CO., Ltd.
    Inventors: Meiling Zhang, Xiaoru Gao, Chao Chen, Yajiang Zhu
  • FAST STARTUP CONTROL CIRCUIT FOR SWITCH MODE POWER SUPPLY
    Publication number: 20170317577
    Abstract: A control circuit for a switch mode power supply (SMPS) includes a power switch for coupling to a primary winding of the power supply and a startup resistor coupled to an external input voltage and to a control terminal of the power switch. The control circuit also includes a controller. During startup, the controller is configured to cause the power switch to amplify a startup current from an external input voltage through the startup resistor and provide a startup power to the controller. During normal operation, the controller is configured to provide a power switch control signal to turn on and off the power switch for controlling a current flow in the primary winding and regulating an output of the power supply. The controller is configured to provide a current signal for driving an NPN power switch and to provide a voltage signal for driving an NMOS power switch.
    Type: Application
    Filed: July 17, 2017
    Publication date: November 2, 2017
    Inventors: MEILING ZHANG, XIAORU GAO, CHAO CHEN, YAJIANG ZHU
  • Speaker
    Patent number: D830329
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: October 9, 2018
    Assignee: Dolby Laboratories Licensing Corporation
    Inventors: George Trasmonte, Meiling Zhang, Kelvin Francis Griffiths
  • Speaker
    Patent number: D888007
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: June 23, 2020
    Assignee: Dolby Laboratories Licensing Corporation
    Inventors: George Trasmonte, Meiling Zhang, Kelvin Francis Griffiths