Patents by Inventor Melanie Yorke

Melanie Yorke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • vWFA and/or ANTIG domain containing proteins
    Patent number: 8222371
    Abstract: Proteins (INSP141, INSP142, INSP143, and INSP144) identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease are described.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: July 17, 2012
    Assignee: Ares Trading S.A.
    Inventors: Mark Douglas Davies, David Michalovich, Melanie Yorke, Christine Power
  • Cell surface glycoprotein
    Patent number: 8124748
    Abstract: This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: February 28, 2012
    Assignee: Ares Trading S.A.
    Inventors: Stephen Fitzgerald, Richard Fagan, Jadwiga Bienkowska, Christine Power, Melanie Yorke-Smith
  • CSF3R polypeptides and uses thereof
    Patent number: 7871979
    Abstract: The present invention relates to CSF3R polypeptide variants and their uses, particularly for therapeutic or prophylactic treatment in human subjects. The invention also relates to nucleic acids encoding said polypeptides, vectors comprising such nucleic acids and recombinant cells containing the same. The invention further discloses methods of producing such polypeptides, as well as methods and tools for detecting or dosing these polypeptides in any sample.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: January 18, 2011
    Assignee: Merck Serono SA
    Inventors: Melanie Yorke-Smith, Andreas Pigni
  • TREATMENT AND/OR PREVENTION OF CANCER AND/OR ARTHRITIS
    Publication number: 20100303760
    Abstract: The invention relates to the use of INSP163 for treatment and/or prevention of cancer and/or musculoskeletal/connective tissue disorder, in particular of lung cancer and/or osteoarthritis. Combinations of INSP163 with an interferon, a TNF antagonist or a further anti-cancer or anti-arthritis agent are also within the present invention.
    Type: Application
    Filed: April 20, 2006
    Publication date: December 2, 2010
    Applicant: Laboratoires Serono SA
    Inventors: Christine Power, Melanie Yorke-Smith
  • REELER DOMAIN CONTAINING PROTEIN
    Publication number: 20100196349
    Abstract: This invention relates to protein INSP 171, herein identified as containing a Reeler domain, and to the use of this protein and the nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: December 4, 2006
    Publication date: August 5, 2010
    Applicant: ARES TRADING S.A.
    Inventors: Christine Power, Melanie Yorke-Smith, Richard Fagan, Tania Rodrigues, Dave Michalovich
  • Isolated INSP 163 protein
    Patent number: 7700724
    Abstract: This invention relates to the novel protein, termed INSP163, herein identified as a secreted protein containing a jelly-roll fold, in particular, as a member of the TNF (tumor necrosis factor)-like family of cytokines, specifically as a C1q-like protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: April 20, 2010
    Assignee: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke, Jadwiga Bienkowska
  • Cystine-Knot Fold Cytokine
    Publication number: 20100048467
    Abstract: This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: January 12, 2006
    Publication date: February 25, 2010
    Applicant: ARES TRADING S.A.
    Inventors: Mark Douglas Davies, Christopher Benjamin Phelps, Richard Joseph Fagan, Christine Power, Melanie Yorke, Mark Ibberson, Yan Lavrovsky
  • CSF3R POLYPEPTIDES AND USES THEREOF
    Publication number: 20100004167
    Abstract: The present invention relates to CSF3R polypeptide variants and their uses, particularly for therapeutic or prophylactic treatment in human subjects. The invention also relates to nucleic acids encoding said polypeptides, vectors comprising such nucleic acids and recombinant cells containing the same. The invention further discloses methods of producing such polypeptides, as well as methods and tools for detecting or dosing these polypeptides in any sample.
    Type: Application
    Filed: July 5, 2007
    Publication date: January 7, 2010
    Applicant: Laboratoires Serono SA
    Inventors: Melanie Yorke-Smith, Andreas Pigni
  • Defensin Proteins
    Publication number: 20090324562
    Abstract: This invention relates to the novel proteins, termed INSP108 and INSP109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: June 30, 2009
    Publication date: December 31, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • Cystine-knot fold protein
    Patent number: 7619065
    Abstract: This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: November 17, 2009
    Assignee: Ares Trading S.A.
    Inventors: Mark Douglas Davies, Christopher Benjamin Phelps, Richard Joseph Fagan, Christine Power, Melanie Yorke, Mark Ibberson
  • Beta defensin proteins
    Patent number: 7563767
    Abstract: This invention relates to novel proteins, termed INSP 108 and INSP 109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: January 13, 2004
    Date of Patent: July 21, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • Splice variant of the human pituitary growth hormone
    Patent number: 7531508
    Abstract: This invention relates to a novel protein, termed INSP101, herein identified as a novel splice variant of human pituitary growth hormone and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention, and treatment of disease.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: May 12, 2009
    Assignee: Ares Trading S.A.
    Inventors: Richard Joseph Fagan, Christopher Benjamin Phelps, Tania Maria Rodrigues, Melanie Yorke, Mariastella De Tiani
  • vWFA and/or ANT_IG Domain Containing Proteins
    Publication number: 20090104197
    Abstract: This invention relates to novel proteins (herein termed INSP141, INSP142, INSP143, and INSP144), herein identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: October 28, 2005
    Publication date: April 23, 2009
    Applicant: Ares Trading S.A.
    Inventors: Mark Douglas Davies, David Michalovich, Melanie Yorke, Christine Power
  • TNF-like secreted protein
    Patent number: 7514533
    Abstract: This invention relates to novel protein INSP058, herein identified as TNF-like secreted protein, and to the use of this protein and the nucleic acid sequence from the encoding gene in the diagnosis, prevention, and treatment of disease.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: April 7, 2009
    Assignee: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Mark Ibberson, Melanie Yorke
  • Defensin Proteins
    Publication number: 20090042775
    Abstract: This invention relates to novel proteins, termed INSP 108 and INSP 109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: January 13, 2004
    Publication date: February 12, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • TREATMENT AND/OR PREVENTION OF CANCER AND/OR ARTHRITIS
    Publication number: 20090035274
    Abstract: The invention relates to the use of INSP163 for treatment and/or prevention of cancer and/or musculoskeletal/connective tissue disorder, in particular of lung cancer and/or osteoarthritis. Combinations of INSP163 with an interferon, a TNF antagonist or a further anti-cancer or anti-arthritis agent are also within the present invention.
    Type: Application
    Filed: April 20, 2006
    Publication date: February 5, 2009
    Applicant: Laboratoires Serono SA
    Inventors: Christine Power, Melanie Yorke-Smith
  • Lipocalin Protein
    Publication number: 20080254035
    Abstract: The invention is based on the discovery that the human protein referred to herein as INSP181 protein is a lipocalin.
    Type: Application
    Filed: March 8, 2006
    Publication date: October 16, 2008
    Applicant: Ares Trading S.A.
    Inventors: Melanie Yorke-Smith, Christine Power, Ursula Boschert
  • Mam Domain Containing Protein
    Publication number: 20080213286
    Abstract: This invention relates to a novel protein, termed INSP152, herein identified as a secreted protein, in particular, as a MAM domain containing protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment.
    Type: Application
    Filed: October 18, 2005
    Publication date: September 4, 2008
    Applicant: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke
  • Lipocalin Protein
    Publication number: 20080196113
    Abstract: The invention is based on the discovery that the human protein referred to herein as INSP153 protein is a lipocalin.
    Type: Application
    Filed: October 14, 2005
    Publication date: August 14, 2008
    Applicant: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke
  • Cell Surface Glycoprotein
    Publication number: 20080124309
    Abstract: This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: August 11, 2005
    Publication date: May 29, 2008
    Applicant: Ares Trading S.A.
    Inventors: Stephen Fitzgerald, Richard Fagan, Jadwiga Bienkowska, Christine Power, Melanie Yorke-Smith