Patents by Inventor Menashe Yacoby

Menashe Yacoby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10478594
    Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium, and apparatus for delivery the device, are provided. The delivery apparatus may include one or more latching legs, a release ring, a pull chord, and a catheter wherein the latching legs are configured to engage the device for delivery. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: November 19, 2019
    Assignee: V-Wave Ltd.
    Inventors: Menashe Yacoby, Boaz Harari, Yaacov Nitzan
  • Publication number: 20190254814
    Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum, and a drug-eluting biodegradable material that biodegrades over time to release a drug that limits tissue overgrowth. The inventive device also may include a biodegradable material that biodegrades to offset flow changes caused by tissue overgrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits.
    Type: Application
    Filed: April 25, 2019
    Publication date: August 22, 2019
    Applicant: V-Wave Ltd.
    Inventors: Yaacov NITZAN, Menashe Yacoby, Neal Eigler, James Whiting, Erez Rozenfeld
  • Patent number: 10369033
    Abstract: A delivery system that includes a catheter, a balloon, a self-expanding prosthesis, and a sheath. The sheath including an opening in a wall of the sheath that initiates rupturing of the sheath so that the self-expanding prosthesis may move from its compressed state to its expanded state. Additionally, a distal end portion of the balloon that is distal to a distal end of the sheath includes an enlarged diameter portion, the enlarged diameter portion having approximately the same outer diameter as an outer diameter of the sheath when the self-expanding prosthesis is in its compressed state, and the enlarged diameter portion being the maximum outer diameter of the balloon when the self-expanding prosthesis is in its compressed state.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: August 6, 2019
    Assignee: MERIT MEDICAL IRELAND LIMITED
    Inventors: Menashe Yacoby, Ascher Shmulewitz, Raz Bar-On, Gil Naor, Damian Kelly, Michael Gilmore, Mark Steckel
  • Patent number: 10368981
    Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive device may include a biodegradable material that biodegrades to offset flow changes caused by tissue ingrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: August 6, 2019
    Assignee: V-Wave Ltd.
    Inventors: Yaacov Nitzan, Menashe Yacoby
  • Publication number: 20190223877
    Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. In one embodiment, an indwelling catheter can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter can include first and second restrictors each configured to at least partially occlude the vein within which the catheter is implanted and thus to restrict fluid flow within the vein when the restrictors are activated. The restrictors can each be configured to move between an activated configuration, in which the restrictor occludes the vein, and a relaxed configuration, in which the restrictor does not occlude the vein. The catheter can include a pump, such as an axial motor pump, configured to pump fluid through the catheter.
    Type: Application
    Filed: April 2, 2019
    Publication date: July 25, 2019
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Publication number: 20190183629
    Abstract: Apparatus and methods are described including inserting an implantable device (20) into a blood vessel of a subject while the implantable device is disposed inside a delivery device and is constrained in a constrained configuration by the delivery device. The implantable device is released from the delivery device into the blood vessel, thereby causing the implantable device to assume a non-constrained configuration by an upstream end of the implantable device radially expanding (120), a central portion (122) of the implantable device radially expanding such that along the central portion of the implantable device the inner surface (24) of the implantable device defines a diverging portion (25) of a conduit (26), and the implantable device forming a folded portion (128) between the upstream end of the implantable device and the central portion of the implantable device. Other applications are also described.
    Type: Application
    Filed: August 10, 2017
    Publication date: June 20, 2019
    Inventors: Sagy Karavany, Tanhum Feld, Boaz Nishri, Menashe Yacoby
  • Patent number: 10300254
    Abstract: Various systems and methods are provided for treating pulmonary edema. In general, a pump can be configured to be implanted within a patient at risk of developing edema. The pump can be configured to pump fluid out of the patient's lungs, e.g., out of the patient's interstitial and alveolar spaces. The pump can be configured to be fully implanted within the patient's body. The pump can be configured to continuously pump fluid, or the pump can be configured to be selectively actuatable in response to a trigger event. In an exemplary embodiment, the pump can include an inflow port coupled to an inflow tube in fluid communication with a lymphatic vessel of the patient, and can include an outflow port coupled to an outflow tube in fluid communication with a vein of the patient.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: May 28, 2019
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 10285708
    Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. In one embodiment, an indwelling catheter can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter can include first and second restrictors each configured to at least partially occlude the vein within which the catheter is implanted and thus to restrict fluid flow within the vein when the restrictors are activated. The restrictors can each be configured to move between an activated configuration, in which the restrictor occludes the vein, and a relaxed configuration, in which the restrictor does not occlude the vein. The catheter can include a pump, such as an axial motor pump, configured to pump fluid through the catheter.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: May 14, 2019
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Publication number: 20190117943
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Application
    Filed: December 19, 2018
    Publication date: April 25, 2019
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Publication number: 20190117944
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Application
    Filed: December 19, 2018
    Publication date: April 25, 2019
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 10251740
    Abstract: A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: April 9, 2019
    Assignee: V-Wave Ltd.
    Inventors: Neal Eigler, Lior Rosen, Werner Hafelfinger, Erez Rozenfeld, Tamir Ben-David, Nir Nae, Menashe Yacoby, Yaacov Nitzan
  • Publication number: 20190083761
    Abstract: Various systems and methods are provided for treating pulmonary edema. In general, a pump can be configured to be implanted within a patient at risk of developing edema. The pump can be configured to pump fluid out of the patient's lungs, e.g., out of the patient's interstitial and alveolar spaces. The pump can be configured to be fully implanted within the patient's body. The pump can be configured to continuously pump fluid, or the pump can be configured to be selectively actuatable in response to a trigger event. In an exemplary embodiment, the pump can include an inflow port coupled to an inflow tube in fluid communication with a lymphatic vessel of the patient, and can include an outflow port coupled to an outflow tube in fluid communication with a vein of the patient.
    Type: Application
    Filed: November 21, 2018
    Publication date: March 21, 2019
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 10207086
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: February 19, 2019
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 10195405
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: February 5, 2019
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Publication number: 20190015188
    Abstract: A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism.
    Type: Application
    Filed: September 13, 2018
    Publication date: January 17, 2019
    Applicant: V-Wave Ltd.
    Inventors: Neal EIGLER, Lior ROSEN, Werner HAFELFINGER, Erez ROZENFELD, Tamir BEN-DAVID, Nir NAE, Menashe YACOBY, Yaacov NITZAN
  • Publication number: 20190008628
    Abstract: A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism.
    Type: Application
    Filed: September 13, 2018
    Publication date: January 10, 2019
    Inventors: Neal EIGLER, Lior ROSEN, Werner HAFELFINGER, Erez ROZENFELD, Tamir BEN-DAVID, Nir NAE, Menashe YACOBY, Yaacov NITZAN
  • Patent number: 10154846
    Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. In one embodiment, an indwelling catheter can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter can include first and second restrictors each configured to at least partially occlude the vein within which the catheter is implanted and thus to restrict fluid flow within the vein when the restrictors are activated. The restrictors can each be configured to move between an activated configuration, in which the restrictor occludes the vein, and a relaxed configuration, in which the restrictor does not occlude the vein. The catheter can include a pump, such as an axial motor pump, configured to pump fluid through the catheter.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: December 18, 2018
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 10149684
    Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. In one embodiment, an indwelling catheter can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter can include first and second restrictors each configured to at least partially occlude the vein within which the catheter is implanted and thus to restrict fluid flow within the vein when the restrictors are activated. The restrictors can each be configured to move between an activated configuration, in which the restrictor occludes the vein, and a relaxed configuration, in which the restrictor does not occlude the vein. The catheter can include a pump, such as an axial motor pump, configured to pump fluid through the catheter.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: December 11, 2018
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Publication number: 20180263766
    Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.
    Type: Application
    Filed: May 24, 2018
    Publication date: September 20, 2018
    Applicant: V-Wave Ltd.
    Inventors: Yaacov NITZAN, Menashe YACOBY
  • Patent number: 10076403
    Abstract: A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: September 18, 2018
    Assignee: V-Wave Ltd.
    Inventors: Neal Eigler, Lior Rosen, Werner Hafelfinger, Erez Rozenfeld, Tamir Ben-David, Nir Nae, Menashe Yacoby, Yaacov Nitzan