Patents by Inventor Menashe Yacoby
Menashe Yacoby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11224503Abstract: Apparatus and methods are described including inserting an implantable device (20) into a blood vessel of a subject while the implantable device is disposed inside a delivery device and is constrained in a constrained configuration by the delivery device. The implantable device is released from the delivery device into the blood vessel, thereby causing the implantable device to assume a non-constrained configuration by an upstream end of the implantable device radially expanding (120), a central portion (122) of the implantable device radially expanding such that along the central portion of the implantable device the inner surface (24) of the implantable device defines a diverging portion (25) of a conduit (26), and the implantable device forming a folded portion (128) between the upstream end of the implantable device and the central portion of the implantable device. Other applications are also described.Type: GrantFiled: August 10, 2017Date of Patent: January 18, 2022Assignee: Hemodynamx-Techologies Ltd.Inventors: Sagy Karavany, Tanhum Feld, Boaz Nishri, Menashe Yacoby
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Patent number: 11207200Abstract: Apparatus and methods are described including implanting an aortic pressure-loss-reduction device (20) in a subject's ascending aorta. While the device is inside a catheter (42), a distal end of the catheter is placed within the ascending aorta. A proximal covering sheath (44) of the catheter is retracted such as to uncover at least a portion of a downstream anchor (31), such that the uncovered portion of the downstream anchor includes a portion of the frame that does not have material coupled thereto. Subsequently, a distal covering sheath (45) of the catheter is advanced, such as to cause an upstream anchor (33) to anchor an upstream end device (20) to the subject's ascending aorta, by the upstream anchor radially expending against an inner wall of the ascending aorta. Other applications are also described.Type: GrantFiled: November 14, 2018Date of Patent: December 28, 2021Assignee: HEMODYNAMX-TECHNOLOGIES LTD.Inventors: Sagy Karavany, Menashe Yacoby, Tanhum Feld
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Patent number: 11179552Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.Type: GrantFiled: April 9, 2020Date of Patent: November 23, 2021Assignee: White Swell Medical LtdInventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
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Patent number: 11179551Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.Type: GrantFiled: April 9, 2020Date of Patent: November 23, 2021Assignee: White Swell Medical LtdInventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
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Patent number: 11179550Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.Type: GrantFiled: December 19, 2018Date of Patent: November 23, 2021Assignee: White Swell Medical LtdInventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
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Patent number: 11166730Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. In one embodiment, an indwelling catheter can be configured to be at least partially implanted within a vein of a patient in the vicinity of an outflow port of a duct of the lymphatic system. The catheter can include first and second restrictors each configured to at least partially occlude the vein within which the catheter is implanted and thus to restrict fluid flow within the vein when the restrictors are activated. The restrictors can each be configured to move between an activated configuration, in which the restrictor occludes the vein, and a relaxed configuration, in which the restrictor does not occlude the vein. The catheter can include a pump, such as an axial motor pump, configured to pump fluid through the catheter.Type: GrantFiled: April 2, 2019Date of Patent: November 9, 2021Assignee: White Swell Medical LtdInventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
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Patent number: 11135054Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum, and a drug-eluting biodegradable material that biodegrades over time to release a drug that limits tissue overgrowth. The inventive device also may include a biodegradable material that biodegrades to offset flow changes caused by tissue overgrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits.Type: GrantFiled: April 25, 2019Date of Patent: October 5, 2021Assignee: V-Wave Ltd.Inventors: Yaacov Nitzan, Menashe Yacoby, Neal Eigler, James Whiting, Erez Rozenfeld
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Publication number: 20210169634Abstract: Apparatus and methods are described including implanting an aortic pressure-loss-reduction device (20) in a subject's ascending aorta. While the device is inside a catheter (42), a distal end of the catheter is placed within the ascending aorta. A proximal covering sheath (44) of the catheter is retracted such as to uncover at least a portion of a downstream anchor (31), such that the uncovered portion of the downstream anchor includes a portion of the frame that does not have material coupled thereto. Subsequently, a distal covering sheath (45) of the catheter is advanced, such as to cause an upstream anchor (33) to anchor an upstream end device (20) to the subject's ascending aorta, by the upstream anchor radially expending against an inner wall of the ascending aorta. Other applications are also described.Type: ApplicationFiled: November 14, 2018Publication date: June 10, 2021Inventors: Sagy Karavany, Menashe Yacoby, Tanhum Feld
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Publication number: 20210161637Abstract: Systems and methods for implanting a shunt for regulating blood pressure between a patient's left and right atria are provided. The shunt comprises an anchor having a neck region, first and second end regions, and a conduit affixed with the anchor formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism. The shunt may be advanced through the sheath until the first region protrudes from the sheath and self-expands within the left atrium. The shunt and the sheath may then be retracted until the first region contacts the left side of the atrial septum. The sheath may further be retracted until the counterforce exerted by shunt tension on the atrial septum overcomes the friction of the retained portions of the shunt such that the second region is exposed from the sheath and self-expands within the second atrium.Type: ApplicationFiled: February 12, 2021Publication date: June 3, 2021Applicant: V-Wave Ltd.Inventors: Neal EIGLER, Nir NAE, Lior ROSEN, Werner HAFELFINGER, Erez ROZENFELD, James S. WHITING, Menashe YACOBY, Yaacov NITZAN
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Publication number: 20210121678Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. A catheter system can include a catheter shaft configured to be at least partially implantable within a patient's vein, a flexible membrane attached to the catheter shaft, the flexible membrane being a collapsible, tube-like member having a lumen extending therethrough, and a single selectively deployable restriction member formed over a portion of the flexible membrane at substantially a midpoint between a proximal end of the flexible membrane and a distal end of the flexible membrane, the restriction member being configured to control a size of the lumen so as to direct a controlled volume of fluid from an upstream side of the restriction member to a downstream side the restriction member.Type: ApplicationFiled: January 5, 2021Publication date: April 29, 2021Inventors: Yaacov Nitzan, Menashe Yacoby, Sagi Raz, Shani Chen, Or Inbar
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Publication number: 20210052378Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.Type: ApplicationFiled: November 6, 2020Publication date: February 25, 2021Applicant: V-Wave Ltd.Inventors: Yaacov NITZAN, Menashe YACOBY
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Patent number: 10926069Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.Type: GrantFiled: May 5, 2020Date of Patent: February 23, 2021Assignee: White Swell Medical LtdInventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
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Patent number: 10925706Abstract: A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism.Type: GrantFiled: September 13, 2018Date of Patent: February 23, 2021Assignee: V-Wave Ltd.Inventors: Neal Eigler, Lior Rosen, Werner Hafelfinger, Erez Rozenfeld, Tamir Ben-David, Nir Nae, Menashe Yacoby, Yaacov Nitzan
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Patent number: 10912873Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. A catheter system can include a catheter shaft configured to be at least partially implantable within a patient's vein, a flexible membrane attached to the catheter shaft, the flexible membrane being a collapsible, tube-like member having a lumen extending therethrough, and a single selectively deployable restriction member formed over a portion of the flexible membrane at substantially a midpoint between a proximal end of the flexible membrane and a distal end of the flexible membrane, the restriction member being configured to control a size of the lumen so as to direct a controlled volume of fluid from an upstream side of the restriction member to a downstream side the restriction member.Type: GrantFiled: March 1, 2018Date of Patent: February 9, 2021Assignee: White Swell Medical LtdInventors: Yaacov Nitzan, Menashe Yacoby, Sagi Raz, Shani Chen, Or Inbar
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Publication number: 20210000581Abstract: A shunt for regulating blood pressure between a patient's left atrium and right atrium comprises an anchor comprising a neck region, first and second end regions, and a conduit affixed with the anchor that formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism.Type: ApplicationFiled: September 13, 2018Publication date: January 7, 2021Applicant: V-Wave Ltd.Inventors: Neal EIGLER, Lior ROSEN, Werner HAFELFINGER, Erez ROZENFELD, Tamir BEN-DAVID, Nir NAE, Menashe YACOBY, Yaacov NITZAN
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Patent number: 10828151Abstract: A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.Type: GrantFiled: May 24, 2018Date of Patent: November 10, 2020Assignee: V-Wave Ltd.Inventors: Yaacov Nitzan, Menashe Yacoby
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Publication number: 20200261706Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.Type: ApplicationFiled: May 5, 2020Publication date: August 20, 2020Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
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Publication number: 20200230380Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.Type: ApplicationFiled: April 9, 2020Publication date: July 23, 2020Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
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Publication number: 20200230381Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.Type: ApplicationFiled: April 9, 2020Publication date: July 23, 2020Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
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Patent number: 10709878Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.Type: GrantFiled: December 19, 2018Date of Patent: July 14, 2020Assignee: White Swell Medical LtdInventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld