Abstract: Apparatuses for cutting tissue include an oscillator assembly and a clamp. The oscillator assembly defines a resonance frequency and includes a frame, an excitation element, and a blade. The frame has an upper portion and a lower portion, and the lower portion is configured to oscillate relative to the upper portion. The excitation element is coupled with the lower portion of the frame, and the excitation element is selectively operable to provide an excitation signal to the oscillator assembly sufficient to cause the oscillator assembly to oscillate at the resonance frequency. The blade is coupled with the lower portion for sectioning tissue. The clamp is selectively moveable along the frame to alter the resonance frequency of the oscillator assembly.

Abstract: A cable status detection circuit comprises an on-chip termination resistor module, a termination discharge module, a status detection signal transmission module, and a status detection signal sampling and judgment module. Among them, the on-chip termination resistor module provides a termination resistor matching the transmission line; the termination discharge module discharges the high-speed interface of the chip to the ground before cable status detection; the status detection signal transmission module is responsible for sending detection signals during cable status detection; and the status detection signal sampling and judgment module samples the voltage status of the high-speed interface after the status detection signal transmission module sends the detection signals, judges the cable status based on the sampling data results, and locates the fault position.

Abstract: High speed laser scanning systems and methods are disclosed for imaging target samples. Embodiments of the laser scanning systems and methods include separating a laser beam into two or more different pathways and pulsing light along the two or more pathways. The different pathways intersect the surface of a moving mirror at different locations and light traveling in a pathway that is being approached by an edge of the moving reflective surface is turned off while light traveling in a different pathway that is farther from the edge of the moving reflective surface is turned on. Embodiments include reflective surfaces that form a rotating polygonal scanner. Further embodiments include recombining the two or more different pathways, focusing the laser light on a test sample, and imaging the light reflected from the test sample.

Abstract: A display apparatus includes a first pixel unit located at the center of a display region and at least one second pixel unit located at an edge of the display region. A first light-emitting element in the first pixel and a first light emission adjustment unit corresponding to the first light-emitting element are not shifted from each other. Along a direction in which the first pixel unit points to the second pixel unit, a second light adjustment center of a second light emission adjustment unit in the second pixel unit and a second light-emitting center of a second light-emitting element corresponding to the second light emission adjustment unit are shifted from each other with a shift. The display region includes a shift linear-variation region. In the shift linear-variation region, shifts vary linearly with image heights of pixel units.

Abstract: Provided are an active and passive integrated fireproof heat-insulating board and a preparation method thereof, including: n passive fireproof layers and n or n+1 active fireproof layers, the passive fireproof layers and the active fireproof layers are overlapped with each other into a whole. Each passive fireproof layer includes an inorganic fiber felt and an aerogel; the aerogel is obtained by curing an aerogel stock solution having adhesiveness, and the aerogel stock solution includes, in parts by mass, 1000 to 4000 parts of silica sol, 50 to 150 parts of soluble silicate, 10 to 50 parts of a phosphate adhesive, 5 to 20 parts of quicklime, 5 to 50 parts of titanium dioxide, 10 to 50 parts of calcium stearate, 5 to 50 parts of a hydrophobic modifier, 5 to 50 parts of an acid-base regulator, and 1000 to 4000 parts of a solvent.

Abstract: In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to scaffold molecules that exhibit potent antimalarial activity against multiple strains of Plasmodium spp. in the parasite's various stages, such as, for example, the erythrocytic and exoerythrocytic stages, and pharmaceutical compositions comprising same. In one aspect, the compounds are tetrahydroacridinones having the structure I described herein. In another aspect, the compounds described herein can be used to treat or prevent malaria in a subject.

Abstract: In one aspect, the disclosure relates to compounds that inhibit Plasmodium falciparum asexual blood stage parasites (PfABS) In one aspect, the compounds exhibit sub-millimolar potency against the intraerythrocytic stages of Plasmodium falciparum and other Plasmodium species. In another aspect, the compounds are soluble in aqueous solutions at pH 7.4, making them suitable for oral administration to patients. Also disclosed are methods of making the compounds, pharmaceutical compositions comprising the same, and methods of treating or preventing malaria using the same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: High speed laser scanning systems and methods are disclosed for imaging target samples. Embodiments of the laser scanning systems and methods include separating a laser beam into two or more different pathways and pulsing light along the two or more pathways. The different pathways intersect the surface of a moving mirror at different locations and light traveling in a pathway that is being approached by an edge of the moving reflective surface is turned off while light traveling in a different pathway that is farther from the edge of the moving reflective surface is turned on. Embodiments include reflective surfaces that form a rotating polygonal scanner. Further embodiments include recombining the two or more different pathways, focusing the laser light on a test sample, and imaging the light reflected from the test sample.

Abstract: Provided are a design method of a display device, a display device and a near-eye display apparatus. The display device includes a substrate, light-emitting elements and a light adjustment layer. The light-emitting elements are located on one side of the substrate and facing a light-emitting surface of the display device, and a pixel opening is configured in each light-emitting element. The light adjustment layer is located on one side of the light-emitting elements away from the substrate. The light adjustment layer includes at least one microlens array and a light-transmitting layer located on one side of the microlens array away from the substrate and covering the microlens array, the microlens array includes at least one microlens unit, and a refractive index of the at least one microlens unit is greater than a refractive index of the light-transmitting layer.

Abstract: Disclosed is a display apparatus. The display apparatus includes a display region. The display region includes a shift linear-variation region and a shift non-linear-variation region. In the shift linear-variation region, shifts vary linearly with image heights of pixel units along the first direction. In the shift non-linear-variation region, shifts vary non-linearly with image heights of pixel units along the first direction. Further disclosed is a near-eye display device.

Abstract: A compound according to Formula (I) or a pharmaceutically acceptable salt thereof: is provided. X1 is N or C—Y; Y is H, halogen, NH2, OH, SH, alkyl, aryl, alkoxy, or aryloxy; A is O, NH, S, Se, or CH2, B is X2 is N or CH; and Z is NH, CH2, S, O, or Se.

Abstract: A confocal microscope system includes a light source configured to form a light beam, a scanning unit, and an objective lens. The scanning unit is in the form of a mechanically driven scanning unit with a controllable scanning trajectory, and is configured to direct the light beam through the scanning trajectory. The objective lens defines a pupil plane and a focal plane. The light beam is directed from the scanning unit to the objective lens. The confocal microscope system is configured for multi-color line-scanning confocal microscopy, and implements multi-color fluorescence imaging without laser excitation crosstalk.

Abstract: The present disclosure discloses a horizontal well cuttings bed processing method and device. The method includes: based on drilling engineering information of a horizontal well, predicting a distribution pattern of a cuttings bed throughout a drilling process, determining a cuttings bed height risk level in each well section, and outputting a cuttings bed removal solution associated with the well section. According to the present disclosure, processing accuracy and processing efficiency of the cuttings bed in a horizontal well can be improved, and accumulation of the cuttings bed in the horizontal well can be effectively resolved.

Abstract: A data processing method and apparatus, a device, and a non-transitory computer-readable storage medium are provided. A target data table is obtained that includes at least two index keywords corresponding to a target object. Metadata information corresponding to the target data table is merged to obtain a metadata management table. Feature mapping is performed on data in the target data table according to the metadata management table in order to obtain data features corresponding to the at least two index keywords in the target data table and in order to generate data feature tables. The data feature tables are merged to obtain an index table. A metadata management table is constructed through the metadata information of the target data table. An index table corresponding to the target data table is generated according to the metadata management table to implement the inverted index of the data through the index table.

Abstract: A confocal microscope system includes a light source configured to form a light beam, a scanning unit, and an objective lens. The scanning unit is in the form of a mechanically driven scanning unit with a controllable scanning trajectory, and is configured to direct the light beam through the scanning trajectory. The objective lens defines a pupil plane and a focal plane. The light beam is directed from the scanning unit to the objective lens. The confocal microscope system is configured for multi-color line-scanning confocal microscopy, and implements multi-color fluorescence imaging without laser excitation crosstalk.

Abstract: A display apparatus includes a first pixel unit located at the center of a display region and at least one second pixel unit located at an edge of the display region. A first light-emitting element in the first pixel and a first light emission adjustment unit corresponding to the first light-emitting element are not shifted from each other. Along a direction in which the first pixel unit points to the second pixel unit, a second light adjustment center of a second light emission adjustment unit in the second pixel unit and a second light-emitting center of a second light-emitting element corresponding to the second light emission adjustment unit are shifted from each other with a shift. The display region includes a shift linear-variation region. In the shift linear-variation region, shifts vary linearly with image heights of pixel units.

Abstract: Disclosed is a display apparatus. The display apparatus includes a display region. The display region includes a shift linear-variation region and a shift non-linear-variation region. In the shift linear-variation region, shifts vary linearly with image heights of pixel units along the first direction. In the shift non-linear-variation region, shifts vary non-linearly with image heights of pixel units along the first direction. Further disclosed is a near-eye display device.

Abstract: Provided are a design method of a display device, a display device and a near-eye display apparatus. The display device includes a substrate, light-emitting elements and a light adjustment layer. The light-emitting elements are located on one side of the substrate and facing a light-emitting surface of the display device, and a pixel opening is configured in each light-emitting element. The light adjustment layer is located on one side of the light-emitting elements away from the substrate. The light adjustment layer includes at least one microlens array and a light-transmitting layer located on one side of the microlens array away from the substrate and covering the microlens array, the microlens array includes at least one microlens unit, and a refractive index of the at least one microlens unit is greater than a refractive index of the light-transmitting layer.

Abstract: A method for evaluating a downhole working condition of a PDC bit includes: performing an indoor test, including performing a drilling test in different full-sized cores by using the PDC bit with different degrees of abrasion and balling under condition of given WOB and rotational speed, to acquire change characteristics of a WOB, a rotational speed, a torque, a ROP and a bit vibration of the PDC bit in different time domains; improving and perfecting an existing prediction model and evaluation method for the downhole working condition through data obtained by the test to obtain the method; reading parameters of the WOB, the rotational speed, the torque and the ROP in real time during drilling; determining the downhole working condition of the PDC bit by using the method in the improving and perfecting.

Abstract: An apparatus for large-scale dynamic imaging of a sample is described. The apparatus includes an optical detector, a light guide, a dichroic beam splitter, and a light source. The light guide includes a first portion and a second portion. The second defines a tapered shape such that a first diameter defined by a distal end of the second portion is smaller than a second diameter defined by a proximal end of the second portion. The dichroic beam splitter is positioned between the first portion and the second portion of the light guide. The light source is configured to direct a light beam through an external surface of the dichroic beam splitter. The dichroic beam splitter is configured to direct the light beam toward the second open end of the light guide and transfer the return emitted signal through the light guide to the optical detector.