Patents by Inventor Menotti Calvani

Menotti Calvani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acetyl L-carnitine for the preparation of a medicament for the prevention of painful peripheral neuropathy in patients with type 2 diabetes
    Patent number: 8952059
    Abstract: Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: February 10, 2015
    Assignee: Sigma-Tau Industrie Faramceutiche Riunite S.p.A.
    Inventors: Antonino Amato, Menotti Calvani
  • ACETYL L-CARNITINE FOR THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION OF PAINFUL PERIPHERAL NEUROPATHY IN PATIENTS WITH TYPE 2 DIABETES
    Publication number: 20140024712
    Abstract: Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 23, 2014
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Antonino AMATO, Menotti CALVANI
  • Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes
    Patent number: 8569366
    Abstract: Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: October 29, 2013
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Antonino Amato, Menotti Calvani
  • Compounds having antitumor activity
    Patent number: 8314144
    Abstract: Disclosed is the use of compounds of formula (I) wherein X, Y and Z are as defined in the description of the invention, for the preparation of an antitumor medicament, optionally in combination with different biologically active substances.
    Type: Grant
    Filed: January 7, 2010
    Date of Patent: November 20, 2012
    Assignee: Defiante Farmaceutica, S.A.
    Inventors: Gianfranco Peluso, Menotti Calvani
  • Use of the acetyl L-carnitine in association with the biotin for the treatment of patients with type 2 insulin-resistant diabetes mellitus
    Patent number: 8053472
    Abstract: The invention relates to the use of the acetyl L-carnitine in association with the biotin for the treatment of patients with Type 2 insulin-resistant diabetes mellitus.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: November 8, 2011
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Menotti Calvani
  • COMPOSITION USEFUL FOR THE PREVENTION OF ADVERSE EFFECT DUE TO THE USE OF PPAR-GAMMA AGONISTS
    Publication number: 20100305204
    Abstract: The present invention relates to the use of acetyl L-carnitine, or a pharmaceutically acceptable salt thereof, for the prevention of the adverse effects, such as osteoporosis, weight gain and edema, due to the use of PPAR-gamma agonists selected from the group consisting of spirolaxine or a glitazonederivative selected from the group consisting of roglitazone, pioglitazone androsiglitazone.
    Type: Application
    Filed: April 28, 2008
    Publication date: December 2, 2010
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Menotti Calvani, Stefania D'Iddio, Paola Benatti
  • Use of L-Carnitine as stabilizing agent of proteins
    Patent number: 7833977
    Abstract: The present invention relates to the technical field of stabilizing proteins, in particular to the therapeutic aspects of protein stabilization. L-carnitine is a useful agent for stabilizing proteins, and in a particularly favourable aspect in proteins used in the medical field. In a preferred aspect, L-carnitine is used for protecting chaperone activity, and in the medical field for preserving the activity of altered chaperone proteins. In connection with this invention L-carnitine is used for the preparation of a medicament for the treatment of diseases due to altered chaperone proteins, such as eye diseases, in particular cataract.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: November 16, 2010
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Menotti Calvani
  • Compounds Having Antitumor Activity
    Publication number: 20100227791
    Abstract: Disclosed is the use of compounds of formula (I) wherein X, Y and Z are as defined in the description of the invention, for the preparation of an antitumor medicament, optionally in combination with different biologically active substances.
    Type: Application
    Filed: January 7, 2010
    Publication date: September 9, 2010
    Inventors: Gianfranco Peluso, Menotti Calvani
  • Compounds having antitumor activity
    Patent number: 7652066
    Abstract: Disclosed is the use of compounds of formula (I) wherein X, Y and Z are as defined in the description of the invention, for the preparation of an antitumor medicament, optionally in combination with different biologically active substances.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: January 26, 2010
    Assignee: Defiante Farmaceutica Lda.
    Inventors: Gianfranco Peluso, Menotti Calvani
  • Use of acetyl L-carnitine for the preparation of a medication for the preventive therapy for pain
    Publication number: 20090062388
    Abstract: The invention relates to the use of the acetyl L-carnitine, or a pharmaceutically acceptable salt thereof for the preparation of a medication for the preventive therapy for pain.
    Type: Application
    Filed: September 26, 2008
    Publication date: March 5, 2009
    Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Menotti Calvani, Luigi Mosconi
  • Use of the acetyl L-carnitine in association with the biotin for the treatment of patients with type 2 insulin-resistant diabetes mellitus
    Publication number: 20080269307
    Abstract: The invention relates to the use of the acetyl L-carnitine in association with the biotin for the treatment of patients with Type 2 insulin-resistant diabetes mellitus.
    Type: Application
    Filed: July 2, 2008
    Publication date: October 30, 2008
    Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Menotti Calvani
  • Compounds Having Antitumor Activity
    Publication number: 20080227683
    Abstract: Disclosed is the use of compounds of formula (I) wherein X, Y and Z are as defined in the description of the invention, for the preparation of an antitumor medicament, optionally in combination with different biologically active substances.
    Type: Application
    Filed: February 8, 2005
    Publication date: September 18, 2008
    Applicant: DEFIANTE FARMACEUTICA LDA
    Inventors: Gianfranco Peluso, Menotti Calvani
  • Acetyl L-Carnitine For Preventing Painful Peripheral Diabetic Neuropathy
    Publication number: 20080161604
    Abstract: The use of acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is described for the preparation of a medicament useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which said symptoms are selected from the group consisting of pain, paraesthesia and hyperaesthesia, in which the acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Application
    Filed: April 18, 2006
    Publication date: July 3, 2008
    Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
    Inventors: Menotti Calvani, Antonino Amato
  • Use of Acetyl L-Carnitine for the Preparation of a Medicine for the Treatment of Neuropathic Pain in Diabetic Patients
    Publication number: 20070213408
    Abstract: The use of acetyl L-carnitine, or one of its pharmaceutically acceptable salts, is described for the treatment of neu-ropathic pain in patients with type 2 diabetes not treated with insulin.
    Type: Application
    Filed: April 5, 2005
    Publication date: September 13, 2007
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Menotti Calvani, Antonino Amato
  • Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes
    Publication number: 20060241058
    Abstract: Acetyl L-carnitine, or of one of its pharmaceutically acceptable salts, is useful for the prevention of painful peripheral neuropathy in patients suffering from type 2 diabetes, in which symptoms are pain, paraesthesia or hyperaesthesia. The acetyl L-carnitine is administered orally at a dose of at least 3 grams/day.
    Type: Application
    Filed: April 26, 2005
    Publication date: October 26, 2006
    Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Antonino Amato, Menotti Calvani
  • Use of an alkanoyl L-carnitine for the preparation of a medication to treat anhedonia
    Publication number: 20060148896
    Abstract: The present invention relates to the use of an alkanoyl L-carnitine, or pharmaceutically acceptable salt thereof, for the preparation of a medicament for the treatment of anhedonia.
    Type: Application
    Filed: December 20, 2005
    Publication date: July 6, 2006
    Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Menotti Calvani, Luigi Mosconi
  • Use of acetyl L-carnitine for the preparation of a medicine for the treatment of neuropathic pain in diabetic patients
    Publication number: 20060004095
    Abstract: Acetyl L-carnitine is used to treat neuropathic pain in patients with type 2 diabetes who are not treated with insulin.
    Type: Application
    Filed: October 21, 2004
    Publication date: January 5, 2006
    Inventors: Menotti Calvani, Antonino Amato
  • Composition comprising ketanserin AND AN ALKANOYL L-CARNITINE FOR THE TREATMENT OF CRPS
    Publication number: 20040209906
    Abstract: The use of ketanserin in combination with L-carnitine, some alkanoyl L-carnitines and the pharmacologically acceptable salts thereof is disclosed for the treatment of CRPS.
    Type: Application
    Filed: April 28, 2003
    Publication date: October 21, 2004
    Applicant: Sigma-Tau industrie Farmaceutiche Riunite S.p.A.
    Inventors: Claudio Cavazza, Menotti Calvani
  • Use of an alkanoyl l-carnitine for the preparation of a medication to treat anhedonia
    Publication number: 20040171685
    Abstract: The present invention relates to the use of an alkanoyl L-carnitine, or a pharmaceutically acceptable salt thereof, for the preparation of a medicament for the treatment of anhedonia.
    Type: Application
    Filed: November 26, 2003
    Publication date: September 2, 2004
    Inventors: Menotti Calvani, Luigi Mosconi
  • Use of acetyl l-carnitine for the prepartion of a medication for the preventive therapy for pain
    Publication number: 20040152781
    Abstract: The invention relates to the use of the acetyl L-carnitine, or a pharmaceutically acceptable salt thereof for the preparation of a medication for the preventive therapy for pain.
    Type: Application
    Filed: March 4, 2004
    Publication date: August 5, 2004
    Inventors: Menotti Calvani, Luigi Mosconi