Patents by Inventor Menotti Calvani

Menotti Calvani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040142879
    Abstract: The invention relates to the use of the acetyl L-carnitine in association with the biotin for the treatment of patients, with type 2 insulin-resistant diabetes mellitus.
    Type: Application
    Filed: November 21, 2003
    Publication date: July 22, 2004
    Inventor: Menotti Calvani
  • Publication number: 20040120967
    Abstract: The present invention relates to the technical field of stabilizing proteins, in particular to the therapeutic aspects of protein stabilization. L-carnitine is a useful agent for stabilizing proteins, and in a particularly favourable aspect in proteins used in the medical field. In a preferred aspect, L-carnitine is used for protecting chaperone activity, and in the medical field for preserving the activity of altered chaperone proteins. In connection with this invention L-carnitine is used for the preparation of a medicament for the treatment of diseases due to altered chaperone proteins, such as eye diseases, in particular cataract.
    Type: Application
    Filed: December 1, 2003
    Publication date: June 24, 2004
    Inventor: Menotti Calvani
  • Publication number: 20030220363
    Abstract: The present invention relates to the use of propionyl L-carnitine and the pharmaceutically acceptable salts thereof for the preparation of medicaments useful in the treatment of pathologies whose treatment gains a benefit from inducement of apoptosis, in particular blood vessels, such as restenosis after angioplasty or coronary stenting, or in particular tumors.
    Type: Application
    Filed: February 3, 2003
    Publication date: November 27, 2003
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.p.A.
    Inventors: Menotti Calvani, Claudio Pisano
  • Publication number: 20020091092
    Abstract: The present invention relates to the use of propionyl L-carnitine and the pharmaceutically acceptable salts thereof for the preparation of medicaments useful in the treatment of pathologies whose treatment gains a benefit from inducement of apoptosis, in particular blood vessels, such as restenosis after angioplasty or coronary stenting, or in particular tumors.
    Type: Application
    Filed: May 7, 2001
    Publication date: July 11, 2002
    Inventors: Menotti Calvani, Claudio Pisano
  • Patent number: 6214884
    Abstract: This invention relates to L-carnitine and lower alkanoyl L-carnitines in combination with ketanserin, for the therapeutic treatment of Chronic Regional Pain Syndrome (CRPS).
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: April 10, 2001
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Claudio Cavazza, Menotti Calvani
  • Patent number: 5958941
    Abstract: The use of L-carnitine or of an alkanoyl L-carnitine or their pharmacologically acceptable salts is described for producing a medicament for inhibiting nephrotoxicity and vasculotoxicity resulting from the administration of an immunosuppressant drug such as cyclosporin-A, tacrolimus, rapamicine and deoxyspergualine.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: September 28, 1999
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Menotti Calvani, Luigi Mosconi
  • Patent number: 5955424
    Abstract: The use of L-carnitine or of an alkanoyl L-carnitine or their pharmacologically acceptable salts is described for producing a medicament for inhibiting nephrotoxicity and vasculotoxicity resulting from the administration of an immunosuppressant drug such as cyclosporin-A, tacrolimus, rapamicine and deoxyspergualine.
    Type: Grant
    Filed: January 3, 1996
    Date of Patent: September 21, 1999
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Menotti Calvani, Luigi Mosconi
  • Patent number: 5753703
    Abstract: A novel therapeutic use of L-carnitine or alkanoyl L-carnitine is disclosed in combination with a polyunsaturated fatty acid of the omega-3 series, for the prevention and the treatment of lipid metabolism disorders and cardiovascular disorders.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: May 19, 1998
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Claudio Cavazza, Menotti Calvani
  • Patent number: 4751242
    Abstract: Oral or parenteral administration of 1,000-2,000 mg/day of acetyl L-carnitine or an equivalent amount of a pharmacologically acceptable salt thereof to patients affected by acute or chronic peripheral neuropathy dramatically improves their symptomatological pattern.
    Type: Grant
    Filed: July 27, 1987
    Date of Patent: June 14, 1988
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Menotti Calvani, Luigi Mosconi
  • Patent number: 4346107
    Abstract: A pharmaceutical composition administerable either orally or parenterally, comprising a therapeutically effective amount of an acyl-carnitine, or a pharmaceutically acceptable salt, ester or amide thereof, wherein the acyl radical is selected from the group formed by acetyl, propionyl, butyryl, hydroxybutyryl and acetoacetyl is useful in the therapeutical treatment of patients with impaired cerebral metabolism, as for instance in the states of senile and presenile psychomotor involution and in senile and presenile dementia.
    Type: Grant
    Filed: February 5, 1980
    Date of Patent: August 24, 1982
    Assignee: Claudio Cavazza
    Inventors: Claudio Cavazza, Menotti Calvani