Patents by Inventor Merl F. Hoekstra

Merl F. Hoekstra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tyrosine kinase
    Patent number: 5705377
    Abstract: Tyrosine kinase mutant and wild-type genes useful in screening compositions which may affect DNA double-strand break repair activity.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: January 6, 1998
    Assignee: The Salk Institute for Biological Studies
    Inventor: Merl F. Hoekstra
  • Protein kinases
    Patent number: 5686412
    Abstract: Protein kinase mutant and wild-type genes encoding polypeptides of the class heretofore designated "casein kinase I" and useful in screening compositions which may affect DNA double-strand break repair activity are disclosed. Also disclosed are methods using the polynucleotides in cell-proliferative disorders.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: November 11, 1997
    Assignee: Salk Institute for Biological Studies
    Inventor: Merl F. Hoekstra
  • Protein kinases
    Patent number: 5627064
    Abstract: Protein kinase mutant and wild-type genes encoding polypeptides of the class heretofore designated "casein kinase I" and useful in screening compositions which may affect DNA double-strand break repair activity are disclosed. Also disclosed are methods using the polynucleotides in cell-proliferative disorders.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: May 6, 1997
    Assignee: The Salk Institute For Biological Studies
    Inventor: Merl F. Hoekstra
  • G protein-coupled receptor kinase GRK6
    Patent number: 5591618
    Abstract: The present invention provides purified and isolated polynucleotide sequences encoding the novel G protein-coupled receptor kinase designated GRK6. Also provided by the invention are methods and materials for the recombinant production of GRK6 enzyme and methods for identifying compounds which modulate the protein kinase activity of GRK6.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: January 7, 1997
    Assignee: ICOS Corporation
    Inventors: David Chantry, Patrick W. Gray, Merl F. Hoekstra
  • G protein-coupled receptor kinase GRK6
    Patent number: 5532151
    Abstract: The present invention provides purified and isolated polynucleotide sequences encoding the novel G protein-coupled receptor kinase designated GRK6. Also provided by the invention are methods and materials for the recombinant production of GRK6 enzyme and methods for identifying compounds which modulate the protein kinase activity of GRK6.
    Type: Grant
    Filed: March 31, 1994
    Date of Patent: July 2, 1996
    Assignee: ICOS Corporation
    Inventors: David Chantry, Patrick W. Gray, Merl F. Hoekstra